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Volume 30 (1978)
- Issue 6 Pages 533-
- Issue 5 Pages 417-
- Issue 4 Pages 297-
- Issue 3 Pages 201-
- Issue 2 Pages 93-
- Issue 1 Pages 1-
Volume 30, Issue 3
Displaying 1-8 of 8 articles from this issue
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Masafumi SHINTANI1978 Volume 30 Issue 3 Pages 201-210
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIn an attempt to clarify the uteroplacental blood flow (UPBF) and its regulation system in normal and abnormal pregnancies, we studied UPBF in SD strain rats by using the double tracer microspheres method free of anesthesia and restraint, and we proposed the significance of “shunt flow” in myometrium which was considered to be a regulator in UPBF.
Pregnancy with hypertension was produced by intramuscular injection of methylprednisolone (20 mg/rat). Spontaneous hypertensive rats (SHR) were also used. Prolonged pregnancy was produced by consecutive intramuscular injection of progesterone (5mg/rat) from the 18th day of gestation. Pregnancy with diabetes mellitus (DM) was produced by single intravenous injection of streptozotocin(65 mg/kg) at the 11th day. The blood pressure in normal and abnormal rats was measured by programmed electrosphygmomanometer PE-300 (Narco Bio-System Inc. ).
The UPBF, only 0.5% in nonpregnant rats, tended to increase with pregnant days. In normal pregnancy the observed rate of UPBF was 11%(peak) on the 18th and 10% on the 20th day. The UPBF in the pregnancy with MP-induced hypertension was 5.9%, the shunt rate was 0%, and fetal mortality rate increased on the 20th day of gestation. In the pregnancy of SHR, the UPBF was 8.9%, its shunt rate was 20%, and fetal mortality rate was lower than that of MP-hypertensive group. These results indicated the reason why the SHR could continue to survive as a strain. The UPBF in DM pregnancy was only 2.7%, its shunt rate was 3.4%, and fetal mortality rate was very high (30%). The UPBF in the prolonged pregnancy group showed a value of 6.6% and its shunt rate was 1.5% on the 23rd day. The blood pressure in normal rats did not change remarkably, but the blood pressure in SHR tended to decrease significantly with pregnancy.
The microangiographic study revealed the existence of the shunt system in the uteroplacental circulation system.
In conclusion, we emphasize the importance of the “shunt flow” as a regulator of the UPBF and fetal development.View full abstractDownload PDF (3714K) -
Shumpei MATSUURA, Yoshio SANDAL, Norimasa SAGAWA, Motoyasu NARIMATSU, ...1978 Volume 30 Issue 3 Pages 211-218
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESS1) The effects of hemorrhage on the maternal uterine and renal artery blood flow were studied in near-term pregnant rabbits. The renal and uterine artery blood flows were measured by square-wave electromagnetic flowmeters and the arterial blood pressure was measured by pressure trnasducer. These flow signals and pressures were electronically integrated and displayed simultaneously on a pen recorder.
2) Before blood removal, the average value of total blood volume measured by the dye dilution method was 271.0ml in the near-term pregnant rabbits, and was significantly larger than that of the 210.0ml in the nonpregnant rabbits. The increase came to 29.0 per cent. The average value of uterine artery blood flow (UABF) and renal artery blood flow (RABF) in pregnant rabbits before blood removal were 14.5ml/mil, 26.0ml/min respectively, and the UABF in the same rabbits was 70.6% greater and the RABF was 9.2% greater than in that of the nonpregnant rabbits.
3) The removal of blood was performed for 60 minutes at the rate of 1ml per minute. After the first 10 minutes of bleeding, RABF and UABF in the nonpregnant rabbits decreased at approximately the same rate. The RABF fell to 41.6% and the UABF to 27.1% of each pre-hemorrhage level after 60ml bleeding was completed.
4) In the near-term pregnant rabbits, the change rates of RABF and UABF during bleeding were somewhat different from those of the nonpregnant rabbits. The decreaserate of the RABF in pregnant rabbits was slower than in the nonpregnant rabbits, while there was a remarkable decrease of UABF compared with the non-pregnant ones. After 60 minutes of hemorrhaging, the former decrease fell to 57.3% of its pre-hemorrhage level, and the latter decrease to 20.0% of its pre-hemorrhage level.
5) The renal and uterine vascular resistances were calculated from the external iliac artery pressure and the artery blood flow of each organ. The renal vascular resistance of pregnant rabbits stayed always below that of the nonpregnant ones, but the uterine vascular resistance increased over that of the nonpregnant ones, reaching a level of 3.39 times that of pre-bloodremoval.
6) According to the results of this study, it has been observed that the RABF during hemorrhage in pregnancy was reratively unchanged, and it is believed this was due to the lending and borrowing phenomenon between RABF and UABF. In this way, the efficient operation of renal autoregulation and uterine vascular resistance in pregnant women may be facilitated.View full abstractDownload PDF (968K) -
Part II Sexual LifeMasayoshi OSHIMA, Hideki AOCHI, Kanji KASAI1978 Volume 30 Issue 3 Pages 219-225
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIn order to investigate the sexual life of the women in so-called cancer age, we collected 889 women. They were random cases sampled among women who received mass population screening for uterine cancer organized by the Seijin-byo Center (Medical Center for Adult Diseases, Shiga), Shiga prefecture.
The study was done by presenting a representative questionare to 1, 000 women to which we could get satisfactory answers to learn the outline of their sexual life.
Sex decreased in frequency according to the advance of age though still 7.3% of women older than 55 yrs. had sex at least once a week. Sex was usually initiated by husbands and in accordance with the advance of age, the rate of the initiation by the women inclined to increase to the maximum in the age 50- 54 yrs. The women who were younger than 39 yrs, wanted less frequent sex and those older than 45 yrs. more frequent sex.
Most of the women responded to the satisfaction in the actual sexual life. According to the general viewpoints in this study, the women in the age of 40-44 yrs. were most active and, revearsely stated, hungry in the sexual behaviors.View full abstractDownload PDF (1012K) -
Hiroyuki MANDAI, Hideyoshi THUBOUCHI, Nobuyuki FUKADA1978 Volume 30 Issue 3 Pages 227-230
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSThe method of supposed birth weight of newborn infant has been many studied from before. Recently there is report such as ultrasonic studies, but none of the exact and simple method has appeared as yet. We think of height of uterine fundus, abdominal circumference that take in periodically check test of pregnant woman as variable number, used a computer and look for the multiple regression line and made the simple chart of supposed weight of newborn infant.
As the result, if the weight of newborn infant is Y, the height of uterine fundus is X1, and the abdominal circumference is X2.
1) In Y correlated with X1, the correlation coefficient is 0.51, the regression line is calculated as Y=95.201X1+75.485. 2) In Y correlated with X2, the correlation coefficient is 0.46, the regression line is calculated as Y=36.116X2-80.356. 3) In Y correlated with X1 and X2, the multiple correlation coefficient is 0.58, the multiple regression line is calculated as Y=-1370.8+71.488X1+24.258X2. 4) The maternal body weight increase in 10 kg in proportion to 225g of the weight of newborn infant. 5) The mean of weight of newborn infant is 3250±415g (M±SD), the mean of height of uterine fundus is 33.3±2.2cm (M±SD), and the mean of abdominal circumference is 92.2±5.2cm (M±SD), in the weight of newborn infant M±3/2SD is ranged from 2628 to 3873g, in the height of uterine fundus M± 3/2SD is ranged from 30.0 to 36.6 cm, in the abdominal circumference M±3/2SD is ranged from 84.4 to 100.0cm, therefore we think that within the limits of M±3/2SD means AFD. 6) When an error of the supposed weight and the birth weight of newborn infant is±100g, precise ratio is 26%, ±200g is 50%, ±300g is 69%, ±400g is 80%, }500g is 90%.View full abstractDownload PDF (594K) -
Takahisa FUJIKI, Teruhiko TAMAYA, Norio FURUTA, Hiroji OKADA1978 Volume 30 Issue 3 Pages 231-233
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSWe had recentlyo bservedo ne caseo f 13-trisomys yndrome. The mother of the baby was 26 years old, gravida2 para 2 and her familiala nd pasth istoriesw ere not remarkable. Her last menstrualp eriod was on Sept. 5th in 1975. Her prenatal course had been uneventful, and she took neither X-ray nor drugs duringh er pregnancy. On 40 weekso f gestationaal ge, she delivereda femaleb aby (3, 160g)w ith multiple anomalies. The baby died 34 hours after birth. The autopsy revealed hypoplastic mid brain, wideningo f sagitals uture, c leftp alate, harelip, hyperc onvexf inger, p olydactylyfe et, ASD, P DA, accessory pleen, large gallbladder, p olycystick idneya nd horseshoek idney. The chromosomasl tudy revealed4 7, XX, +13. These clinical results indicate 13 trisomy syndrome (Patau's).View full abstractDownload PDF (2178K) -
Seiki KOU, Kenichiro IKUMA, Kazushi TODA, Tadashl TAKEMURA, Shinzo ISO ...1978 Volume 30 Issue 3 Pages 235-237
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSA 28 y. o. woman of 8 weeks gestation had the abdominal surgery due to her repeated severe hypogastralgia under the diagnosis of ectopie pregnancy. On laparotomy, it was found that r-fallopian tube with primary tubal nidation was torn off at the isthmic portion and the distal portion of the tube including fetus migrated in the abdominal cavity and implanted on the omentum below stomach. The end of uterine side of torn off tube was completely healed and formed the scar like narrow band. It seemed to be the small normal tube by looking. The histology of the implant on the omentum showed the typical trophoblast inside of the implanted tube and on the place of implanted omentum.View full abstractDownload PDF (2836K) -
—Endocrinological and Histological Studies on Two Cases—Hayato SHIMADA, Masaaki MAN-I, Hitoshi OKAMURA, Takeshi ASO, Masateru ...1978 Volume 30 Issue 3 Pages 239-246
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSIt has been indicated that certain kinds of non-functioning ovarian tumors show hormonal activity. Two postmenopausal cases, (75 and 71 year-old) who had clinical signs of hyperestrinism, were subjected to the present investigation for the origin of steroid production using hormonal and enzyme-histochemical methods.
Serial determinations of plasma levels of estradiol, androstenedione, progesterone, 17α-hydroxyprogesterone, 20α-dihydroprogesterone, LH, and FSH throughout the pre- and post-operative periods were performed. The pre-operative values of all steroids were higher than those of healthy normalcases in the corresponding age. Conversely, LH and FSH levels were lower. Plasma levels of these steroids were decreased and those of LH and FSH elevated significantly in the post-operative periods.
Histological examinations revealed left ovarian mucinous adenocarcinoma in one case and left ovarian mucinous adenoma combined with right ovarian serous cystadenoma in another case.
3β-hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase activities were demonstrated histochemically in the ovarian stroma of both cases.
It is concluded that the steroid hormone production sites of two postmenopausal cases who had hyperestrinism were the stromal regions of mucinous adenocarcinoma and serous cystadenoma of ovaries.View full abstractDownload PDF (3801K) -
Norlo HIMENO, Shumpei MATSUURA, Masayoshi MURATA1978 Volume 30 Issue 3 Pages 247-253
Published: May 01, 1978
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSA successful pregnancy occurring in a woman after the insertion of two Starr-Edwards prosthetic heart valves is described.
A 28 year old primipara had had a history of rheumatic fever and prolonged valvular disease. In 1971, Starr-Edwards prosthetic heart valves were inserted in each mitral and aortic annul. Atrial fibrillation persisted, though her symptoms improved after the operation. Following a miscarriage in 1976, she became pregnant again in the same year. Although she showed an increase in hepatomegaly and developed a slight cough and palpitation during pregnancy, she was never decompensated, due to full medical supervision based on the evaluation of cardiac function by means of venous pressure measurement and other clinical findings.
Cesarean section was performed in the 41st week because of uterine inertia, and a normal healthy infant was delivered. Her vital signs remained stable during the operation, though her ECG showed steady atrial fibrillation. The infant, a female, had a birth weight of 2, 95Og.
One episode of congestive heart failure in early puerperium was treated successfully with O2 administration and increase dosage of deslanoside and furosemide;subsequent puerperal course was uneventful.
Oral anticoagulants and antibiotics were started after delivery for the prophylaxis of thromboembolism.
Only three successful cases were found in ten foreign reported cases with multiple prosthetic heart valves. It appears, however, that pregnancy in such circumstances is not an unacceptable risk for those under careful medical supervision.
The literature on pregnancy with multiple prosthetic heart valves is reviewed.View full abstractDownload PDF (3064K)
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