ADVANCES IN OBSTETRICS AND GYNECOLOGY
Online ISSN : 1347-6742
Print ISSN : 0370-8446
ISSN-L : 0370-8446
Volume 30, Issue 6
Displaying 1-5 of 5 articles from this issue
  • Shunsuke OHTSU
    1978 Volume 30 Issue 6 Pages 533-543
    Published: November 01, 1978
    Released on J-STAGE: October 11, 2011
    JOURNAL FREE ACCESS
    Various biochemical parameters, namely, urinary estriol as a parameter of function of the feto-placental unit; human placental lactogen (HPL), heat stable alkaline phosphatase (HSAP), leucine aminopeptidase (LAP), lactic dehydrogenase (LDH), β-glucuronidase (β-G) and copper as parameters of metabolic activity of the placenta;and α-fetoprotein (α-FP) as a parameter of function of the fetus were measured simultaneously, continuously with the progress of pregnancy and systematically in normal pregnant women and in patients with toxemia of pregnancy expecially at the later stage of pregnancy, and the dynamic state of each parameter was studied.
    According to the classification by the Japan Society of Obstetrics and Gynecology, the diseases of these patients were divided into severe and mild ones. Further, mild toxemia was classified into 4 types, namely, hypertension type, edema-proteinuria type, edema type and proteinuria type.
    The measured results of these parameters in edema or proteinuria type did not differ from those of normal pregnant women, but the measured values of estriol and hPL in hypertension type and in severe toxemia showed remarkable differences from those of normal pregnant women, and further the values of both parameters in hypertension type and in severe toxemia were evidently lower (P<0.05). Besides, the pattern of slow increase of the height of fundus of uterus measured at the same time, was extremely similar to the changing patterns of estriol and hPL in these disease types. In addition, the body weight of the fetus had a tendency to remain at a lower level and it was remarkable, especially in severe toxemia (P<0.05).
    As the result, estriol, hPL and the height of uterine fundus were found extremely useful as parameters of function of the feto-placental unit in the clinical practice. Besides, a high-degree similarity among changing patterns of measured values of these 3 parameters and low values of the body weight of the fetus in hypertension type and in severe toxemia, suggested presence of a relationship between hypertension and toxemia of pregnancy, namely, a possibility of occurrence of angiospastic or angiosclerotic changes in utero-placental circulatory state in the above disease.
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  • Toshio FUJIWARA, Wakako YOMURA, Kunihiko TAUCHI
    1978 Volume 30 Issue 6 Pages 545-547
    Published: November 01, 1978
    Released on J-STAGE: October 11, 2011
    JOURNAL FREE ACCESS
    In the radical hysterectomy, the lateral base of the cardinal ligament should be well understood topographically. In this paper, the branches of A. iliaca int, and V. iliaca int, especially the common trunk “gemeinsame Truncus, Adachi” were made clear. At the same time, the Mibayashi's method of extirpation of the cardinal ligament was compared with that of Kobayashi.
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  • Michio KINOSHITA, Ikuo YOGO, Isamu SAWARAGI
    1978 Volume 30 Issue 6 Pages 549-559
    Published: November 01, 1978
    Released on J-STAGE: October 11, 2011
    JOURNAL FREE ACCESS
    Diabetes insipidus in association with pregnancy is extremely rare, and has been reported only about 100 cases in foreign literatures and 26 cases in Japan.
    In this paper, one case of diabetes insipidus with pregnancy we have experienced lately is reported. Furthermore, literatures in Japan are reviewed and concomitant influences of pregnancy and diabetes insipidus are discussed.
    Case report:
    H. I., a 23-year-old Japanese female, gravida 1, para 0-0-0-0, who was diagnosed diabetes insipidus at 3 years old, visited our hospital at the 12th week of pregnancy. There were no abnormal findings except for slight aggravation of polyuria and polydipsia until the 38th week of pregnancy when preeclamptic signs appeared. At 39th week pregnancy, she had abruptly eclamptic attack during oxytocin infusion for premature rupture of the membranes. Thereafter, a mature female infant (3480g, Apgar's score 9) was immediately delivered by abdominal cesarean section under the general anesthesia (GOF) without further disturbances. In puerperium, polyuria with polydipsia soon returned to the state at early pregnancy, and toxemic signs disappeared within one week after delivery.
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  • Eise TAKASHIMA
    1978 Volume 30 Issue 6 Pages 561-574
    Published: November 01, 1978
    Released on J-STAGE: October 11, 2011
    JOURNAL FREE ACCESS
    Hysteroscope was used for the detection of cancer in the cervical canal which was undetectable colposcopically. The location and extent of cancerous lesions were investigated and biopsies were performed in the cervical canal with a long and slender forceps under direct vision. Characteristic appearances of cancerous lesions of endocervix were whiteness, opacity, coarseness, unevenness of surface contour with tortuous and engorged irregular vascularity. As invasions progressed, the appearances above mentioned increased their grades, making the most remarkable changes in the vascular features. In the early stage of cancer in the cervical canal, white epithelium, mosaic or punctation were observed hysteroscopically after application of acetic acid. As a result, hysteroscopy was useful to detect cancer strictly located in the cervical canal, to examine discrepancy between cytological and histological diagnoses and to decide suitability for conization.
    Moreover, hysteroscopic observation of the ectccervix applied with acetic acid revealed almost the same findings as with colposcopy. Consequently sequential use of a hysteroscope for the observation of the ectocervix and the endocervix was easily performed. This prccedure was named COLPO-CERVICOSCOPY.
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  • Kiyoji OKUDA, Mitsuaki YAMADA, Itsuo KIKUYAMA, Yoshihito IKEDA, Akira ...
    1978 Volume 30 Issue 6 Pages 575-580
    Published: November 01, 1978
    Released on J-STAGE: October 11, 2011
    JOURNAL FREE ACCESS
    The patient with congenital adrenal hyperplasia (salt-losing form) was reported only in sixty cases in Japan. Recently we encountered a newborn female infant with salt-losing form of congenital adrenal hyperplasia. She had congenital abnormality of the external genitalia, and in the course of the postnatal period she showed poor suckling, vomiting and abdominal distention. Laboratory findings were as follows: low serum sodium(111mEq/ml), low serum choloride(84 mEq/ml) and hyperpotasemia(8.2 mEq/ml).
    Because of pecuriality of these clinical findings and elevation of plasma progesterone(44ng/ml), 17ahydroxyprogesterone (233ng/ml), androstenedione(20ng/ml), testosterone(4.3ng/ml), estradiol(672pg/ml) and ACTH(780pg/ml), we diagnosed this patient as congenital adrenal hyperplasia with salt-losing form by 21-hydroxylase dificiency.
    Administration of sodium chloride, hydrocortisone and DOCA made the clinical symptoms remission, enlarged clitoris reduce, pigmentation of the labia majora fade away, and also serum electrolytes and plasma hormones normalize.
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