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Volume 37 (1985)
- Issue 5-6 Pages 383-
- Issue 4 Pages 243-
- Issue 2-3 Pages 71-
- Issue 1 Pages 1-
Volume 37, Issue 5-6
Displaying 1-8 of 8 articles from this issue
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Masataka OKU, Etsuo USHIODA, Katsutada HIRAOKA, Hideaki IIOKA, Ikuko M ...1985 Volume 37 Issue 5-6 Pages 383-387
Published: November 01, 1985
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSA total of 1026 cases of toxemia of pregnancy were chosen from some 1500 cases collected in cooperation with many hospital and medical facilities in Japan, and examined for the purpose of devising an appropriate scoring system for toxemia of pregnancy.
The toxemia of pregnancy was evaluated by two prognosis ; the maternal prognosis being the incidence of persistent hypertension (PHT) at one month after delivery, the other, the fetal prognosis, being the incidence of IUGR.
In order to research the reciprocal correlations among the factors, cluster analysis, principal component analysis and multiple regression analysis, that is, multivariable analysis, were carried out.
1) The single linkage method was used for cluster analysis. This analysis indicates that edema and edema duration exist in a cluster which is quite different from the other clusters.
2) To adjust the space relation among the factors, principal component analysis was carried out.
3) In multiple regression analysis, fetal body weight, fetal height and persistent hypertension were studied. When parameters were chosen from the view point of the contribution rate, diastolic pressure found to have the highest effect on fetal body weight, followed by proteinuria and diastolic hypertension duration, respectively. The factors having the most effect upon fetal height were diastolic pressure, systolic pressure, diastolic hypertension duration and proteinuria, in order of importance. In the case of persistent hypertension, the order of contribution was seen to be systolic pressure, systolic hypertension duration and diastolic hypertension duration. However, edema was found to contribute little to IUGR and PHT.
4) The correlations between the incidence of IUGR and S-Du, D-Du or P-Du were significant. However, there was no significant correlation between the incidence of IUGR and E-Du.
The incidence of PHT correlated significantly to S-Du and D-Du, but not to P-Du and E-Du.View full abstractDownload PDF (451K) -
Kohei SHIROSHITA, Takara YAMAMOTO, Junko YAMAKI, Hiroji OKADA1985 Volume 37 Issue 5-6 Pages 389-392
Published: November 01, 1985
Released on J-STAGE: December 02, 2011
JOURNAL FREE ACCESSThe activity of androstenedione aromatase (estrogen biosynthetase) was measured in Fallopian tubes from 31 women. Homogenates of the specimens (500 mg w. w. in 2ml of 1/15 M-bisodium phosphate buffer, pH7.4) were incubated with [19-3H, 4-14C]-androstenedione (3H, 1×106 dpm, 14C, 5×103dpm) and 1mg of NADPH at 37°C for 1 h in the air. Using Amberlite XAD-2 resin-charcoal column chromatography, we assayed the activity of aromatizing enzyme for androstenedione by the amount of 3H2O released. In 9 of the 20 pairs of Fallopian tubes from women in the reproductive age, aromatase activity was present; the range was 2 to 19 fmol/h/500 mg w. w., and the difference between the follicular and the luteal phases was not significant. In the specimens from 11 post menopausal women, aromatase activity was not detected (under 10 fmol/h/500 mg w. w.). Thus, there is some androstenedione aromatase activity in human Fallopian tubes, but the level of activity is significantly less than in the myometrium and endometrium. It should be physiologically clarified why the Fallopian tube has aromatase activity.View full abstractDownload PDF (320K) -
Jinsuke YASUDA, Jiro OKUMURA, Gen YAMASHITA, Yoshiro HANADA, Keiko YAM ...1985 Volume 37 Issue 5-6 Pages 393-402
Published: November 01, 1985
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSMeasurements of tumor markers have important implications for monitoring the response to treatment and early diagnosis of the recurrense in patients with ovarian cancer. Serum levels of CA-125, CEA, α-FP, LDH and TAP were measured during the course of therapy for ovarian cancer. The results were as follows:
1) Alterations in CA-125 levels correlated with the disease progression or regression, and CA-125 had the highest usefulness in monitoring the course of therapy.
2) The measurement of α-FP proved superior to measurement of any other markers in patients with α-FP producing from germ cell tumor.
3) The value of CEA had little usefulness for early diagnosis of the recurrence and monitoring tumor in regression or progression.
4) The measurement of LDH and IAP alone had the lowest usefulness because of their minute degree of specificity to ovarian cancer.
But their measurements were convenient and TAP was of use in evaluating patients' immune index during the course of therapy.View full abstractDownload PDF (921K) -
Shinsuke OKAMURA, Yoshiaki OKAMOTO1985 Volume 37 Issue 5-6 Pages 403-419
Published: November 01, 1985
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSInjury during normal coitus is unusual. Since 1920 in Japan 148 cases have been reported. We recently treated a patient with laceration of the vaginal fornix penetrating the peritoneum. The patient was a 41-year-old woman who had had two Caesarian sections. Following sexual intercourse in the usual way, she started bleeding and complained of mild pain. It was considered that the injury was the result of one of three possible causes: postoperative adhesions, cervical deviation to the left, vaginal wall atrophy. Therapy was conservative: the wound was left open, and the patient was treated with bed rest and antibiotics. The 149 cases reported in Japan are reviewed and compared with those reported by Neugebauer and Wenzkowsky.View full abstractDownload PDF (2049K) -
Takao FUNATO, Mlchio HARUTA, Toshinobu SUMIDA, Yoshiaki NAKA, Noriatu ...1985 Volume 37 Issue 5-6 Pages 421-424
Published: November 01, 1985
Released on J-STAGE: December 02, 2011
JOURNAL FREE ACCESSMalignant change arising in benign cystic teratoma (BCT) of the ovary are rare. This phenomenon is seen to occur in 1.8% of BCTs according to Peterson.
Malignant transformation (squamous cell carcinoma) in a BCT was found in a 45-years-old woman. She was admitted mainly because of lumbago. Metastases to lymph nodes and dissemination of the pelvic peritoneum were found at laparotomy. She developed obstruction of the urinary tract soon after operation and survived for 2 years and 9 months with nephrostomy, lineac and Bleomycin-Mitomycin therapies.View full abstractDownload PDF (2751K) -
Kazume OKADA, Yoshinori SUZUKI, Takashi KITANAKA, Atsuo HIDAKA, Tadash ...1985 Volume 37 Issue 5-6 Pages 425-430
Published: November 01, 1985
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSThe case is a 24-year-old woman who often discharge urinary stones and her laboratory data showed mild decrease of renal function at 24 gestational weeks. Being suspected of primary hyperparathyroidism, we measured her serum level of PTH, calcium and phosphate. Her laboratory data showed high concentrations of serum parathyroid hormone (1.3ng/ml), serum calcium and low concentration of serum phosphate.
So she was diagnosed as primary hyperparathyroidism during pregnancy.
During pregnancy, hypertension was appeared. But her parathyroid function was not so significantly increased that we followed up only under low calcium diet.
At 34 gestational weeks, her parathyroid function was increased and she delivered 1, 900g male baby. In order to prevent from dehydration and calcium crisis, she was given 1, 000ml of physiological saline a day. On the postpartum 37th day, subtotal parathyroidectomy was performed (its histologic type was adenoma). After operation, her serum PTH, calcium and phosphate was nomalized.
Meanwhile, serum calcium concentration of newborn was low level and neonatal tetany was appeared, so he was given gluconate calciuml, calcium lactate, 12-OH-D3, and low phosphorus high calcium milk for about 50 days.
Because of this therapy, neonatal tetany was disappeared and his serum calcium and phosphate level was normalized.View full abstractDownload PDF (599K) -
1985 Volume 37 Issue 5-6 Pages 541-561
Published: November 01, 1985
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSDownload PDF (2059K) -
1985 Volume 37 Issue 5-6 Pages 563-641
Published: November 01, 1985
Released on J-STAGE: October 11, 2011
JOURNAL FREE ACCESSDownload PDF (31639K)
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