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Volume 42 (1990)
- Issue 6 Pages 683-
- Issue 5 Pages 575-
- Issue 4 Pages 467-
- Issue 3 Pages 289-
- Issue 2 Pages 171-
- Issue 1 Pages 1-
Volume 42, Issue 4
Displaying 1-10 of 10 articles from this issue
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Tomoko OKA1990 Volume 42 Issue 4 Pages 467-477
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESS5 K Dalton apoprotein in the amniotic fluid was measured with a method of ELISA using the rabbit antibody against 5 K Dalton apoprotein prepared from bovine lung.
As a result, the immunologically cross-reactive substance was found in the amniotic fluid, which showed a exponential increase after around 28 weeks of gestation. Six out of 96 infants born after 28 weeks of gestation suffered from RDS. The levels of 5 K Dalton apoprotein of these infants with RDS were all less than 50 ng/ml, while such pulmonary maturation indicators as L/S ratio, phosphatidyl glycerol and foam stability index test failed to predict RDS.
Further study was performed to clearify the physiological significance of measuring this substance in the amniotic fluid. It was proved that 5 K Dalton apoprotein in the amniotic fluid originated from the fetal lung, and also it was found that a method of determining the concentration of 5 K Dalton apoprotein was a reliable and sensitive procedure for prediction of RDS even with a sample contaminated by blood and/or meconium.View full abstractDownload PDF (1603K) -
Eisaku OKAMOTO, Nagatoshi SUGITA, Tetsu TAKAGI, Itsuko IWATA, Eriko NI ...1990 Volume 42 Issue 4 Pages 479-484
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSImmunoreactive corticotropin-releasing hormone (IR-CRH) in maternal plasma increases progressively during pregnancy and decreases rapidly after delivery, suggesting that IR-CRH is produced in the placenta. We studied immunohistochemical localization of CRH in developing human placenta, decidua, the amniotic membrane and a fresh surgical specimen of hydatidiform mole by Avidin-Biotin Complex staining. Our results were as follows :
(1) IR-CRH was localized in cytotrophoblasts of the placenta, and decidua in the first trimester and in the amniotic membrane at term.
(2) Immunohistochemical localization of CRH was not detected in trophoblasts of a hydatidiform mole.
These results suggest that the sources of the increased level of IR-CRH in human plasma and amniotic fluid during pregnancy are the placenta, decidua and amniotic membrane. The production of IR-CRH in trophoblast of hydatidiform mole may be supressed because of the characteristic change of trophoblast.View full abstractDownload PDF (7828K) -
Eisaku OKAMOTO, Yoshiro OTSUKI, Tetsu TAKAGI, Nagatoshi SUGITA, Osamu ...1990 Volume 42 Issue 4 Pages 485-490
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSChanges in plasma concentration of immunoreactive (IR) 8-arginine vasopressin (AVP) during pregnancy and at delivery were examined by using a highly sensitive radioimmunoassay (RIA). The following results were obtained :
(1) The maternal plasma concentrations of IR-AVP decreased gradually during pregnancy and reached a plateau level after week 28 till delivery. From week 28, the plasma concentrations of IR -AVP were significantly lower than those before week 15 (2.4±0.36 pg/ml). Maternal plasma IR-AVP levels at normal vaginal delivery did not differ from those at delivery by elective cesarean section.
(2) The umbilical arterial plasma concentrations of IR-AVP at vaginal delivery (390±60.6 pg/ ml) which were significantly higher than those of umbilical venous plasma (224±34.1 pg/ml) were remarkably higher than at delivery by cesarean section (14.1±9.1 pg/ml).
(3) The fact that that the concentrations of IR-AVP in the umbilical arterial plasma at delivery in cases of asphyxia (505±74.1 pg/ml) were significantly higher than those at normal delivery (300± 13.3 pg/ml) is noteworthy.
These results suggest that :
(1) In mother, AVP acts as an antidiuretic hormone to maintain the homeostasis of physiologically increased total body water and decreased body tonicity associated with pregnancy.
(2) In fetus, AVP acts as a stress hormone to maintain the homeostasis of cardiovascular and metabolic systems which are subjected to the influence of labour.View full abstractDownload PDF (926K) -
Umio MIYAMOTO1990 Volume 42 Issue 4 Pages 491-492
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSLH, hCG, β-hCG, testosterone (T), total estriol (tE3) and free estriol (fE3) in cord blood were assayed by radioimmunoassay and the levels in males and females were compared.
There were no significant differences between male and female infant samples of cord blood LH, hCG, tE3 and fE3.
But mean cord serum T concentration of male neonates was significantly higher than that of female neonates and mean cord serum, β-hCG concentration of female neonates was significantly higher than that of male neonates.
These data confirm the sex difference in cord serum, β-hCG and T concentrations.View full abstractDownload PDF (290K) -
Kazunori TANAKA, JO KITAWAKI, Jinsuke YASUDA, Yoshiko KATOH, Hideo HON ...1990 Volume 42 Issue 4 Pages 493-498
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSCongenital defect of the vagina is estimated to occur once in every 4, 000-5, 000 female births, and about 5% of those women have a funcitioning uterus. We present a case of congenital defect of the vagina with functioning uterus. The patient was a 15-year-old girl, who had had cyclic lower abdominal cramping since 12 years of age. Her height was 155 cm and her weight 55 Kg. Her vital sings were normal, and her secondary sexual characteristics were adequate. The basal body temperature was biphasic. On pelvic examination, the external genitalia were normal. The vagina terminated blindly 1 cm inside the introitus. Rectal examination revealed that the uterus was normal in size and shape. Chromosome study showed a 46XX karyotype. Intravenous pyelography revealed no urinary tract anomalies. We selected simple surgical reconstruction of the vagina with uterine conservation. The uterine body was incised vertically to reveal a bicornate uterine cavity which ended blindly above the hypoplastic and non-canalized cervix. The blind termination of the vagina was incised and elongated, and.the potential vaginal cavity was canalized and dilated. Stenosis of the neovagina was prevented by the insertion of a Hegar's cervical dilator (no. 18) for ten minutes every night and sanitary tampons during the daytime. Cyclic and painless menstruations now occur without any stenosis or consequent infection.
Other reports of congenital defect of the vagina with functioning uterus are summarized and discussed.View full abstractDownload PDF (4439K) -
Yoshiaki YAMAMOTO, Sakae INABA, Akiko YAMAMOTO, Yoshiki TAKAHASHI, Tat ...1990 Volume 42 Issue 4 Pages 499-505
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSUsing an immunoadsorbent column (IM-P), we have found an effective treatment of blood group incompatible pregnancy (anti Diego b) with minimum side effects. The patient had a history of blood transfusion given at 12 years of age, and her first child had required exchange transfusion. She had a high titer of IgG anti-Dib before this pregnancy. Because the ΔOD 450 values of the amniotic fluid were elevated to zone 2 A of Liley's graph at 32 weeks of gestation, we performed plasma cleaning with IM-P. After the first treatment, the ΔOD 450 value fell to zone 3 of Liley's graph, and the anti-Dib titer in the maternal blood was kept at low levels by three more plasma cleanings until delivery. A viable mature but anemic newborn was delivered at 38 weeks of gestation and required exchange transfusion.
The immunoadsorbent column (IM-P) is a muliporous polyvinyl alcohol gel, on which surface phenylalanine is immobilized as a ligand. This column has been used for systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) patients. As plasma protein did not decrease after plasma cleaning with this column, neither fresh frozen plasma nor plasma protein fraction was required for this procedure. They are required for plasmapheresis and sometimes cause hepatitis. Plasma IgG and IgA values fell sligtly with this treatment, but no other abnormal values were noted.This immunoadsorbent column may be applicable for the management of other blood type incompatible pregnancies.View full abstractDownload PDF (1198K) -
Kazuhiro IWASAKU, Mamoru TOSAKI, Itsuo OHTANI, Kazuyosi HATSUDA, Jinsu ...1990 Volume 42 Issue 4 Pages 507-513
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSWe investigated Chlamydia Trachomatis (CT) infection by the Chlamydiazyme or Micro TrakTMmethods in outpatients of 3 hospitals in Kyoto Prefecture : Kyoto Prefectural Hospital (in the city), Yamashiro Public Hospital (southern district) and Fukuchiyama National Hospital (northern district). The positive rate of CT infection in the respective hospitals was 4.6%, 2.2% and 6.4% (mean 3.9%) for all outpatients, and 4.2%, 1.5% and 6.1% (mean 3.2%) for pregnant women. All 36 pregnant women with CT infection who had been treated for two weeks and became negative for CT had normal deliveries and their babies demonstrated no signs of infection during the neonatal period. The positive rate of CT infection was 12.8% and 6.5% in the case of abortion and sterility, respectively. Among general outpatients in the 3 respective hospitals, the positive rete of CT infection was 4.0%, 4.75 (including Cutis-Fitz-Hugh syndrome) and 8.2% (including one case of tonsillitis).This study revealed a high rate of CT infection in the northern district, indicating that counter measures should be established for CT infection.View full abstractDownload PDF (2210K) -
Masaki MANDAI, Hiroaki ITO, Shozo TANADA, Hayato NIWA, Yoshiyuki IHARA ...1990 Volume 42 Issue 4 Pages 515-520
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSTwo cases of fetal cystic hygroma were presented. In the first case, at 17 weeks' of gestation, ultrasonographic examination showed a large cystic multiseptated mass in the nuchal region of the fetus, whose mother was a 41-year-old woman of gravida 3, para 2. Since no defects of the fetal skull or spine were found, a diagnosis of fetal cystic hygroma was made. Generalized hydrops developed and resulted in intrauterine fetal death at 21 weeks' of gestation.
In the second case, fetal cystic hygroma was diagnosed in a 21-year-old primigravida at 18 weeks' of gestation. Amniocentesis at 19 weeks' of gestation revealed a 45 XO karyotype (Turner's syndrome). The pregnancy was terminated at 20 weeks' of gestation at the parents' request.
When a fetus is diagnosed as having fetal cystic hygroma, genetic amniocentesis should be performed to supplement the decision for the management of the pregnancy.View full abstractDownload PDF (3944K) -
Seiji HAYASHI, Yoshimitsu KOHLITA, Isao FUJII1990 Volume 42 Issue 4 Pages 521-526
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSTranscatheter arterial chemoembolization (TACE) is one of the established therapeutic modalities for treatment of metastatic liver cancer originating in the gastrointestinal tract. However, TACE is seldomly applied to metastatic liver cancer from gynecological regions. We present two cases of multiple liver metastases of uterine cervical cancer, treated with TACE using cisplatin 60 mg/m2, etoposide 200mg/m2 and lipiodol. In both cases, hepatomegaly was markedly reduced, tumor-markers dropped to within or close to the normal range, and subjective symptoms disappeared. No serious complications occurred, and symptomatic side effects and laboratory abnormalities were all transient and curable by conservative therapies. Under adequate medical care, TACE can safely be applied, although there are some reports about fatal complications. The present cases encourage us to actively treat liver metastases of gynecologic neoplasms by TACE as we do those of gastrointestinal neoplasms.View full abstractDownload PDF (4835K) -
Takuzi KANEKO, Yasuhiko YANAGAWA, Hideki KAMEGAI, Yoshihiko FUKUDA, Yo ...1990 Volume 42 Issue 4 Pages 527-530
Published: 1990
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSTubal interstitial pregnancy comprises about 2 % of all ectopic pregnancies, and the diagnosis is rather difficult by conventional methods. Recently we treated a patient with tubal interstitial pregnancy. A combination of ultrasound, hysteroscopy and laparoscopy was useful in the diagnosis.
The patient was a 45-year-old housewife. A ultrasound examination was performed in the ninth week, but no gestational sac was seen in the uterine cavity. A hysteroscopic examination revealed a dilated left ostium and a degenerated tissue in the dilated tube. Left tubal interstitial pregnancy was suspected and laparoscopy was performed. A dark red hemisphere-shaped tumor, 3 cm in diameter, was found in the left interstitial portion of the fallopian tube, and total abdominal hysterectomy with left adnexectomy was performed. A hystological examination confirmed left tubal interstitial pregnancy.View full abstractDownload PDF (5107K)
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