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Volume 43 (1991)
- Issue 6 Pages 591-
- Issue 5 Pages 513-
- Issue 4 Pages 347-
- Issue 3 Pages 191-
- Issue 2 Pages 117-
- Issue 1 Pages 1-
Volume 43, Issue 2
Displaying 1-6 of 6 articles from this issue
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Kensuke SAITO1991 Volume 43 Issue 2 Pages 117-127
Published: 1991
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSDetailed analysis of the familial mode of infection of human T lymphotropic virus type-1 (HTLV-I) by studies of many family trees suggests that the virus is transmitted from mother to child and from husband to wife.
Breast-feeding is a major factor in HTLV-I mother to child infection. HTLV-I infection was detected by both HTLV-I antigen and antibody tests. A follow-up study performed 12 months after birth revealed that 45% of breast-fed babies tested positive for HTLV-I antigen compared to only 2% of bottle-fed babies. Similar follow-up study performed 24 months after birth revealed that 77% of breast-fed babies tested positive for HTLV-I antigen compared to 5% of bottle-fed babies. The HTLV-I infection rate was much lower in bottle-fed babies than in breast-fed babies.
The rate of infection of children born to HTLV-I seropositive mothers did not correlate with the mother's HTLV-I antibody titer, breast feeding period, and breast feeding within transitional antibody persisting period.
Original mother's lymphocyte count in peripheral lymphocytes of breast-fed babies was only 2 to 105. Experimental oral administration of milk lymphocytes to new-born rats revealed that the lymphocytes existed in the submucosa of the intestine.
These results suggest that HTLV-I mother to child infection is attributable to breast feeding and can be prevented by bottle-feeding.View full abstractDownload PDF (4341K) -
Partial isolation of Anemia-inducing substance (AIS) and basic study on removal of AIS by plasmapheresisMasaaki DEGUCHI, Osamu ISHIKO, Kozo HIRAI, Keizo NAKA, Ichiro TATSUTA, ...1991 Volume 43 Issue 2 Pages 128-137
Published: 1991
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSAnemia-inducing substance (AIS) appears in plasma with cancer progress. As reported by us previously, AIS binds to red blood cells (RBC) and immunologically competent cells to induce cancer anemia and immunodeficiency eventually. The rationale of plasmapheresis using normal RBC is based on this character of AIS. In this study, we first clarified the properties of AIS isolated from cancer tissue by affinity chromatography and used a non-coating charcoal column to remove AIS from the cachectic plasma. The following results were obtained.
1) Isolated AIS was heat-sensitive and alkali-resistant.
2) It showed a specific peak at about 100, 000 MW by gel filtration.
3) AIS could be completely removed by 6 rounds of adsorption using a non-coating charcoal column.
4) Similar data were obtained in the experiment using VX-2 transplanted rabbits.
These observations raised the possibility of plasmapheresis with a non-coating charcoal column as a new means of immunotherapy for advanced cancer.View full abstractDownload PDF (3118K) -
Tetsuro HONDA, Yoshiyuki IHARA, Ken HAYASHI, Masumi YOSHIDA, Ikuo KONI ...1991 Volume 43 Issue 2 Pages 138-144
Published: 1991
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSWe present a case of pregnancy complicated by idiopathic hypoparathyroidism. The patient was a 27-year-old primipara. At age 25, she was diagnosed as having idiopathic hypoparathyroidism. Since then she had been given a daily dose of 9g of calcium lactate and 4μg of lα (OH) vitamin D to prevent hypocalcemia. She later became pregnant and was referred to our clinic because of severe nausea and vomiting at 17 weeks' gestation. Laboratory findings revealed hypercalcemia. Supplementation with calcium was discontinued, and only vitamin D was administered. At 40 weeks' gestation she was delivered of a 2, 638g healthy female infant by caesarean section. Although the reason why she needed no calcium during pregnancy remains unknown, serum calcium level should be checked frequently in a pregnancy complicated by hypoparathyroidism.View full abstractDownload PDF (1133K) -
Umio MIYAMOTO, Michio TAKAKI, Hiroshi KATSURAGAWA, Masumi YOSHIDA1991 Volume 43 Issue 2 Pages 145-146
Published: 1991
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESS -
Hiroyuki NAKATANI, Yoshiharu SARUWATARI, Yoshihide OKUMURA, Shigeki UE ...1991 Volume 43 Issue 2 Pages 147-152
Published: 1991
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSRecently, a great deal of attention has been paid to HELLP symdrome (severe toxemia with elevated liver enzymes, low platelet count). Two patients who had been diagnosed as having HELLP syndrome, went through a period of satisfactorily recovery following cesarean section. The authors also examind PIH (pregnancy-induced hypertension) treated hospital and report on liver function in light of their previous studies.View full abstractDownload PDF (834K) -
Masahide SHIOTANI, Yoichi NODA, Katsuhiko NARIMOTO, Takahide MORI, Mik ...1991 Volume 43 Issue 2 Pages 153-160
Published: 1991
Released on J-STAGE: July 05, 2011
JOURNAL FREE ACCESSDeep colorectal endometriosis is not a frequent disorder, and only 56 cases have been reported in Japan. It is very difficult to make its preoperative diagnosis, because the patients primarily suffer from bowel disturbances. In this paper we reported 3 cases of deep colorectal endometriosis, which had been diagnosed preoperatively as a colorectal cancer associated with bowel symptoms.
Cases 1, 2 and 3 were aged in 45, 32 and 44 years old, respectively, and had no gynecological symptom. They were admitted to the hospital with bowel symptoms such as constipation, nausea, vomiting, diarrhea or melena. Objective findings by barium enema and endoscopy revealed the elevated lesions and narrowings in the rectum in Cases 1 and 2, and in the sigmoid colon in Case3. Pathological findings of the specimens biopsied under a endoscopy showed chronic inflammation with fibrosis, and no evidence of endometriosis and malignancy in all cases.
The patients were laparotomized as a colorectal cancer, as clinically suspected of malignancy. Laparotomic findings showed a firm tumor in the rectum in Cases 1 and 2, and in the sigmoid colon in case 3. Pathological diagnoses were rectal endometriosis in Cases 1 and 2, and endometriosis in sigmaid colon in Case 3, containing endometrial glands and stromal tissues in all 3 cases.
Deep colorectal endometriosis is often diagnosed clinically as a colorectal cancer. To avoid a overtreatment, it is important to make its precise diagnosis preoperatively. Characteristically, bowel symptoms were reported to augment in deep colorectal endometriosis in the menstrual phase. Actually, retrospective data showed that melena had begun just prior to the menstruation in Case 2. This report suggests that the biopsy under a endoscopy should be carried out in the menstrual phase to make a precise diagnosis of deep colorectal endometriosis.View full abstractDownload PDF (11262K)
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