産婦人科の進歩

Meigs症候群を呈した卵巣線維腫の1症例

塩谷朋弘, 伊熊健一郎, 柴原浩章, 岡田幾久子, 竹村正

1993 年 45 巻 4 号 p. 465-472
発行日: 1993年
公開日: 2011/07/05

DOIhttps://doi.org/10.11437/sanpunosinpo1949.45.465

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Recently, the definition of Meigs' syndrome was extended from ovarian tumor to various lower abdominal tumors complicated with ascites and hydrothorax.
In one of our patient's Meigs' 'syndrome resulted from fibroma of the right ovary. She was a50 year-old woman, married, gravida 2, para 2, who complained of swelling of the lower abdomen.
Examination disclosed bilateral pleural effusion and ascites.
Her abdomen was diffusely distended, and a rigid mass was palpable from the pelvis to the umbilicus. Abdominal total hysterectomy with bilateral salpingo-oophorectomy was carried out.
A right ovarian mass (weighing 800g) was proved histologically to be a fibroma.
Removal of the mass was followed by subsidence of the pleural effusion and the ascites. The serum levels of CAl25 and SLX were elevated preoperatively, but they returned to normal range after surgery. [Adv Obstet Gynecol 45 (4); 465-472, 1993 (H5.7)]

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子宮頸部ぶどう状肉腫 (胎児型横紋筋肉腫) の1例

高原得栄, 清木康雄, 山田隆司, 植木實, 杉本修, 吉田貞一

1993 年 45 巻 4 号 p. 473-478
発行日: 1993年
公開日: 2011/07/05

DOIhttps://doi.org/10.11437/sanpunosinpo1949.45.473

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Sarcoma botryoides of the uterine cervix was diagnosed in an 18-year-old female. In March, 1991, she had intermenstrual vaginal bleeding, and on July 4 examination in a local clinic revealed a cervical polyp. On the following day she was referred to our department. A polypoid pale yellow edematous tumor protruded from the uterus through the cervix into the vagina. The tumor was removed and examined immediately. The histological diagnosis was sarcoma botryoides, so she was admitted for further examinations and treatment. Special stains of the tissue showed no striated muscle, but myoglobin and desmin were demonstrated, confirming the diagnosis of sarcoma botryoides. On July 18 a modified radical hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphnode resection was performed. The grade of malignancy was reported as Group I (The International Rhabdomyosarcoma Study classification). The patient received three courses of VAC (vincristine, actinomycin-D, cyclophosphamide) as postoperative chemotherapy. She was discharged from the hospital on October 24, 1991. During the 18 months since then there has been no sign of recurrence. [Adv Obstet Gynecol 45 (4); 473-478, 1993 (H5.7)]

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血中SCC抗原が異常高値を示した卵巣成熟嚢胞性奇形腫の2例

多養哲治, 小笠原利忠, 辺見貴至, 子安保喜, 辻芳之, 竹村正, 礒島晋三

1993 年 45 巻 4 号 p. 479-484
発行日: 1993年
公開日: 2011/07/05

DOIhttps://doi.org/10.11437/sanpunosinpo1949.45.479

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Mature cystic teratoma of the ovary (dermoid cyst) is the most common benign germ cell tumor of its kind. In the rare case of malignant transformation of dermoid cyst, the squamous cell carcinoma type is most common.
In recent years, some reports say that a high level of squamous cell carcinoma associated antigen (SCC Ag) in the sera is useful in diagnosing the malignant transformation of mature cystic teratoma. In this paper, two cases of a dermoid cyst were reported to elevate SCC Ag in the sera, nevertheless no malignant transformation was found in the tumor.
Case 1 is 24 years old, had an over new born head size tumor on left ovary, and her preoperative serum SCC Ag level was 9. 0ng/ml. Case 2 is 28 years old, had a over new born head size tumor on right ovary, and serum SCC Ag was 3.8ng/ml. The histological examination showed the typical mature cystic teratoma. The serum SCC Ag level of both cases rapidly decreased after surgical removal of the tumors. The ABC immunostaining demonstrated the definitive staining of SCC Ag on squamous cell epitherium in the tumor by and SCC Ag monoclonal antibody.
These results suggest that a high level of SCC Ag in sera of patient with dermoid cyst is not necessarily the malignant transformation of these tumors. [Adv Obstet Gynecol 45 (4); 479-484, 1993 (H5.7)]

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第61回腫瘍研究部会記録

山片重房, 吉村誠之, 田村明敏, 椹木晋, 谷口定之, 池内正憲, 池田正典, 別府謙一, 松井義明, 中田好則, 尾 ...

1993 年 45 巻 4 号 p. 485-537
発行日: 1993年
公開日: 2011/07/05

DOIhttps://doi.org/10.11437/sanpunosinpo1949.45.485

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平成4年度第2回内分泌研究部会記録

都竹理, 森本義晴, 池田義和, 大野洋介, 高倉賢二, 田坂慶一, 奥田喜代司, 片山和明, 本田徹郎

1993 年 45 巻 4 号 p. 538-572
発行日: 1993年
公開日: 2011/07/05

DOIhttps://doi.org/10.11437/sanpunosinpo1949.45.538

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