ADVANCES IN OBSTETRICS AND GYNECOLOGY
Online ISSN : 1347-6742
Print ISSN : 0370-8446
ISSN-L : 0370-8446
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Volume 47, Issue 6
Displaying 1-5 of 5 articles from this issue
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  • Changes in calcium metabolism from late pregnancy to puerperium and vertebral bone mineral density in early puerperium
    Satoshi YANO, Noriyuki OHARA, Matsuto MOCHIZUKI, Hajime MORIKAWA
    1995 Volume 47 Issue 6 Pages 789-795
    Published: November 01, 1995
    Released on J-STAGE: July 05, 2011
    DOIhttps://doi.org/10.11437/sanpunosinpo1949.47.789
    JOURNAL FREE ACCESS
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    Maternal calcium metabolism during pregnancy and puerperium was investigated by measuring serum calcium-associated factors and calcium-regulating hormones in 23 lactating women. Vertebral bone mineral density was also measured on the tenth day of lactation.
    1) Serum levels of total calcium before delivery were significantly lower than nonpregnant levels but recovered to the nonpregnant level by the 30th day of puerperium. Serum ionized calcium and urinary calcium/creatinine ratio did not change during pregnancy and puerperium, while serum inorganic phosphorus increased during puerperium.
    2) Serum PTH-M, calcitonin and 1α, 25 (OH) 2D3 increased before delivery compared to the nonpregnant levels and decreased during puerperium. Serum osteocalcin was significantly lower before delivery but increased gradually soon after delivery.
    3) Vertebral bone mineral density measured on the 10th day of puerperium did not differ from that of non-pregnant women. These results suggest that maternal calcium metabolism is enhanced in response to increased fetal demand for calcium. However, this accelerated calcium metabolism turned to the nonpregnant state by the 30th day of puerperium.The changes in calcium metabolism during pregnancy and early puerperium did not affect maternal bone mineral density. [Adv Obstet Gynecol 47 (6); 789-795, 1995 (H7.11)]
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  • Increase in serum levels of type IV collagen and laminin in a patient with a retroperitoneal schwannoma
    Masaaki IWAHASHI, Mareo YAMOTO, Makotom IKOMA, Ryosuke NAKANO
    1995 Volume 47 Issue 6 Pages 796-800
    Published: November 01, 1995
    Released on J-STAGE: July 05, 2011
    DOIhttps://doi.org/10.11437/sanpunosinpo1949.47.796
    JOURNAL FREE ACCESS
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    A schwannoma is rare in the retroperitoneal space. Schwann cells produce components of the basement membrane, such as type IV collagen and laminin. We attempted to evaluate possible use of components of the basement membrane as tumor markers for the retroperitoneal schwannoma, using indirect immunofluorescence method and specific radioimmunoassays (RIA) for type IV collagen and laminin.
    A 63-year-old woman presented with a giant abdominal tumor. Ultrasonography, computed tomography (CT), and drop-infusion pyelography revealed a suspected retroperitoneal tumor. The tumor, weighing 2800g, was removed surgically. The tumor was identified pathologically as a schwannoma.
    Strong immunohistochemical staining for type IV collagen and laminin was observed on sections of the tumor, and these components were localized in the pericellular regions of Schwann cells. Radioimmunoassays revealed that serum levels of these antigens were markedly elevated before surgery and then decreased rapidly after the operation.
    The present findings suggest that schwannomas produce large amounts of type IV collagen and laminin and that these components of the basement membrane might be useful as tumor markers for the diagnosis of schwannomas and the monitoring of subsequent treatment.
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  • A case of mixed germ cell tumor of the ovary composed mainly of choriocarcinoma
    Naoko UEMURA, Fuminori KOBAYASHI, Daizo KOHRITA, Yukiyoshi ISHIKAWA, S ...
    1995 Volume 47 Issue 6 Pages 801-807
    Published: November 01, 1995
    Released on J-STAGE: July 05, 2011
    DOIhttps://doi.org/10.11437/sanpunosinpo1949.47.801
    JOURNAL FREE ACCESS
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    We report a case of malignant mixed germ cell tumor of the ovary, which was composed of choriocarcinoma, embryonal carcinoma, and mature teratoma. A 24-year-old, gravida 4 para 1 woman was found to have a left adnexal mass. Since serum tumor markers, hCG, AFP, and CA19-9 were elevated, the tumor was suspected to be an ovarian mixed germ cell tumor. Exploratory laparotomy revealed a solid tumor of the left ovary with no apparent sign of peritoneal dissemination, and left salpingo-oophorectomy was performed. After the surgery, she received 6 courses of MAC combination chemotherapy, and is well without recurrence. Histopathological examination showed that the main component of the tumor was choriocarcinoma, being associated with embryonal carcinoma and mature teratoma. Immunohistochemically, hCG was localized in choriocarcinoma cells, and AFP was expressed in embryonal carcinoma cells. Clinical management of mixed germ cell tumors of the ovary is discussed. [Adv Obstet Gynecol 47 (6); 801-807, 1995 (H7.11)]
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  • [title in Japanese]
    1995 Volume 47 Issue 6 Pages 808-834
    Published: November 01, 1995
    Released on J-STAGE: July 05, 2011
    DOIhttps://doi.org/10.11437/sanpunosinpo1949.47.808
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  • [title in Japanese]
    1995 Volume 47 Issue 6 Pages 835-868
    Published: November 01, 1995
    Released on J-STAGE: July 05, 2011
    DOIhttps://doi.org/10.11437/sanpunosinpo1949.47.835
    JOURNAL FREE ACCESS
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