ADVANCES IN OBSTETRICS AND GYNECOLOGY
Online ISSN : 1347-6742
Print ISSN : 0370-8446
ISSN-L : 0370-8446
Volume 51, Issue 4
Displaying 1-7 of 7 articles from this issue
  • Masafumi SHINTANI, Ken-ichi BEPPU, Yuko HARA
    1999 Volume 51 Issue 4 Pages 325-332
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    A retrospective study was conducted to find out why among women who received hormone replacement therapy (HRT) at a dose of CEE 0.625mg dialy (207 women for 1 year or more, 104 women for 2 years or more), some of them did not respond to HRT, and to determine the percentage of non-responders to HRT based on lumbar bone mineral density (LBMD) measure, using the DXA method (DPX-L). Non-responders were defined as those women in whom bone loss was higher than the CV of the DXA equipment (0.82 %). The percentage of non-responders was 28.0 % after lyear, and 13.5 % after 2 years. As for the effect of concomitant use of 2.5mg MPA, both the rate of LBMD increase and percentage of responders after 1 year were slightly higher than those observed in the group taking CEE alone, but there was no difference after 2 years. It was observed that the proportion of non-responders was small in the patients with higher age, lower levels of LBMD and higher levels of serum ALP at the start of HRT administration. [Adv Obstet Gynecol 51 (4); 325- 332, 1999 (H11.7)]
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  • Miyo KIYOMIZU, Tomonari UENO, Hiroshi KANNO, Masaaki FUKUOKA, Katumi T ...
    1999 Volume 51 Issue 4 Pages 333-336
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    The VATER association is a complex of multiple malformations, which may be an alteration in the mesodermal differentiation, rarely complicated with 18-trisomy. The patient (a 28-year-old Japanese female, nullipara, 31 weeks of gestation) was referred to our hospital due to premature labor, intrauterine growth retardation and hydroamnios. We suspected the VATER association from the findings of esophageal atresia, radial dysplasia, oligodactyly, single umbilical artery and univentricular heart by amniofetography and ultrasonography. The diagnosis of trisomy-18 was comfirmed by amniotic chromosomal examination. She was delivered vaginaly of a child in the 35 weeks of gestation. The apgar score of the 1372g female newborn at 1 and 5 min. were 1 and 2, respectively. After the birth, the diagnosis of truncs arteriosus was added. The infant died the next day. [Adv Obstet Gynecol 51 (4); 333 - 336, 1999 (H11.7)]
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  • Takashi KANO
    1999 Volume 51 Issue 4 Pages 337-343
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    The efficacy of treatment with Sairei-To (Shosaiko-To-go-Gorei-San) for allogeneic immunoabnormal habitual abortion in which lymphocyte transplantation from husband was either ineffective or contraindicated because of autoimmunoabnormal habitual abortion or because the husband was pathogenic virus carrier was examined. The subjects were 352 patients aged 23 to 44 years with primary recurrent (habitual) abortion (twice 231cases, at least three times [ 12 times at maximum] 121 cases), who had a history of at least 2 early abortions and who did not have uterine myoma, congenital uterine anomalies, cervical incompetence or thyroid dysfunction. HLA class I and II antigens of the couples were typed and the diagnosis of allogeneic immunoabnormal habitual abortion was made for patients with less than two husband-specific class II antigens. Antinuclear a ntibody (ANA)and anti-phospholipid antibodies (IgG anti-cardiolipin [IgG aCL], IgM anti-cardiolipin (IgM aCL), anticardiolipin02 glycoprotein I -complex antibody) were also examined in the wives. The therapeutic results in 119 cases in which lymphocyte transplantation from husbands was indicated were as follows; birth of a live child in 67 cases (56.3 %), and the rate of prevention of abortion was 77.9 %. The rates of prevention of abortion in the patients with ineffective lymphocyte transplantation from the husband, those whose husbands carried pathogenic virus (2 cases), and patients had complicated autoimmnoabnormalities (69 cases; 36.3 °C of the patients with allogeneic immunoabnormal habitual abortion) were 77.7 %, 100.0 %, 64.3 %(ANA), 60.0 % (IgG aCL) and 70.0 % (IgM aCL), respectively, exceeding the reported rate of successive spontaneous abortions. These findings demonstrated that Sairei-To therapy was effective not only for autoimmunoabnormal habitual abortion but also for allogeneic immunoabnormal habitual abortion in which lymphocyte transplantation from the husband was either ineffective or contraindicated. The mechanism of action of Sairei-To was assumed to be biological response modification by Shosaiko-To, its active constituent. [Adv Obstet Gynecol 51(4); 337 343, 1999 (H11.7)]
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  • Hayato NIWA, Daizo KORITA, Naoko HIRANO, Emi KITSUKI, Tsuyoshi NISHIKA ...
    1999 Volume 51 Issue 4 Pages 344-347
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    To study human papilloma virus (HPV) infection in the uterine cervix of patients with cancer or autoimmune disease and normal women, we performed cervical or vaginal smear tests and detected the virus using the polymerase chain reaction (PCR) method. The subjects consisted of 100 women aged 20-86 years, who were classified into four groups based on their past history; a cervical cancer group (n = 6), a group with other cancer (n = 36), an autoimmune disease group (n = 9), and a control group (n = 49). The mean age of the patients with other cancers (50.3±11.3 years) was significantly higher than that of control group (42.0±13.5 years; P < 0.01). Only one of the 42 patients with HPV infection had a cervical smear above class III and all 53 patients in the HPV-negative group were below class II. The rate of HPV infection was not significantly associated with the degree of uterine cervical smear findings. The HPV positive rates in each group were 66.7 %, 44.4 %, 55.6 %, and 34.7 %, respectively. The present findings suggested that careful follow up of HPV infection in patients with autoimmune disease or cancer may be helpful in screening for uterine cervical cancer. [Adv Obstet Gynecol 51(4); 344 - 347, 1999 (H11.7)]
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  • 1999 Volume 51 Issue 4 Pages 348-411
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
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  • 1999 Volume 51 Issue 4 Pages 412-466
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    1999 Volume 51 Issue 4 Pages 467-469
    Published: July 01, 1999
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
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