ADVANCES IN OBSTETRICS AND GYNECOLOGY
Online ISSN : 1347-6742
Print ISSN : 0370-8446
ISSN-L : 0370-8446
Volume 52, Issue 1
Displaying 1-5 of 5 articles from this issue
  • Sakae GOTO, Takako YOKOI, Kenji TAKAKURA, Masaya HIROSE, Toshio KIMURA ...
    2000 Volume 52 Issue 1 Pages 1-5
    Published: January 01, 2000
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    Objective: The efficacy of ovulation induction was investigated in women with infertility despite normal ovulation. Patients: One hundred thirty-one normally ovulatory women received treatment for infertility at the Department of obstetrics and Gynecology of Shiga University of Medical Science from January to December 1998. Women with bilateral tubal occlusion and those whose husbands had azoospermia were excluded. Methods: Patients who did not become pregnant during an observation period of 3months after the first visit received ovulation induction using clomiphene citrate(CC), cyclofenil, or human menopausal gonadotropins(hMG) alone or in combination. The pregnancy rate per cycle of ovulation induction was compared to the spontaneous rate retrospectively. Results: Pregnancy was confirmed in 33 cycles during the pcriod of investigation, including 23 cycles with ovulation induction and 10 spontaneous cycles. Among the 10 spontaneous cycles, 7 occurred with in 3 months after the first visit. After the observation period(3months), the pregnancy rate was significantly higher with ovulation induction than with spontaneous cycles (16 / 374 (4.3%) and 3 /284 (1.1%) respectively). The pregnancy rates for cycles with hMG (4 / 60, 6.7%) and cycles with cyclofenil (5 / 114, 4.4%) were significantly higher than for spontaneous cycles. However, the pregnancy rate for cycles with CC (7 / 209, 3.3%) was not significantly different from that for spontaneous cycles. Conclusion: Ovulation induction with hMG or cyclofenil is effective in increasing the pregnancy rate, while CC is not beneficial for normally ovulatory women. [Adv Obstet Gynecol 52 (1); 1 -- 5, 2000 (H.12.1)]
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  • Hideaki SAWAI, Akinori IDA, Junko MURANAKA, Susumu ADACHI, Eiko WAKIMO ...
    2000 Volume 52 Issue 1 Pages 6-13
    Published: January 01, 2000
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    Inhibin is produced by the syncytiotrophoblast of human placenta during pregnancy and is composed of one a -subunit and one of two related 13 -subunits (inhibin A: a - /3 A or inhibin B: a l3 B). Several foreign studies have shown that maternal serum inhibin A levels are raised on average in second trimester pregnancies affected with Down's syndrome. The purpose of this study was to investigate dimeric inhibin A concentration in the second trimester for normal Japanese pregnancies. Additionally we examined the distribution of inhibin A concentration in Down's syndrome pregnancies. The results indicated almost no variation of the median value across the 146 to 16th week of pregnancy. As negative correlation was observed between concentration of inhibin A and maternal weight, the median MoM should be corrected by the weight of each pregnant woman. Significant correlation was observed between inhibin A and hCG concentration. The increase in the serum concentration of inhibin A from women with affected by Down's syndrome was observed, although the number of pregnancies affected was limited. [Adv Obstet Gynecol 52 (1); 6 13, 2000 (H.12.1)]
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  • Toshihiro HIGASHIYAMA, Takahisa UHSIROYAMA, Naoko OGASAWARA, Minoru UE ...
    2000 Volume 52 Issue 1 Pages 14-18
    Published: January 01, 2000
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
    We report a case of cervical intramural pregnancy at the lower incision line of a previous cesarean section. A 21 year-old multigravida consulted our hospital because of amenorrhea and genital bleeding. Transvaginal ultrasonic imaging revealed that the gestational sac existed in a position away from the endometrium, and a fetus-like shadow was observed in the myometrium. In the operation, we recognized a hen's egg-sized mass at the anterior wall of the uterine body. Although excision of the lesion was attempted in order to preserve the uterus, hemostasis became difficult and hysterectomy was performed. Histologically, the part in which the tunica muscularis was perpendicularly thin from the cervix of the uterus to the conversion division (near the histological internal os of the uterus)existed. The gestational sac was recognized to be located within the tunica muscularis. Pregnancy developing in a previous cesarean section scar is the rarest kind of all ectopic pregnancies. It seems to be important to accurately comfirm the implantation position in the diagnosis in the early stage of pregnancy. [Adv Obstet Gynecol 52 (1); 14 18, 2000 (H.12.1)]
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  • 2000 Volume 52 Issue 1 Pages 19-39
    Published: January 01, 2000
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
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  • 2000 Volume 52 Issue 1 Pages 58-97
    Published: January 01, 2000
    Released on J-STAGE: September 27, 2010
    JOURNAL FREE ACCESS
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