We investigated the development of technique to cope with middle age body odor (ABO) by two suggested ways, 1) intercept the key component of ABO that is nonenal on the way of generation; 2) using ABO masking-able or variation-able fragrance, match to the character of ABO. In the first way, we developed
in vitro ABO generation system by coexistence of palmitoleic acid and squalenemonohydroperoxide. Thiotaurine, a prominent biomedical antioxidant, was selected by this
in vitro system for the ingredient to cut off the generation of nonenal. The using test of protocol product including thiotaurine was down the skin nonenal level and had an effect on suppression of ABO generation. Next, we developed the model-ABO that general people considered the middle age body odor. We use the model-ABO to test the fragrance efficacy of masking or variation. Based on this screening test, some effective fragrance was developed, and protocol product fragrant with that effective fragrance had the ability to prevent the odor of ABO in the using test. The application of technique we investigated shown the way for the product of cope with ABO.
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