We investigated a novel artificial membrane to be utilized in the
in vitro method for evaluating the photoprotective efficacy of sunscreens. Although other types of membrane have been developed, for example, Transpore
TM surgical tape (3M Health Care), problems have been experienced, such as 1) membranes absorb or adsorb UV filters, and 2) the characteristics of their surfaces are far from that of the human skin. We overcame these problems with the development of a new membrane. UV light is highly transparent through our membrane and there is minimal absorption of UV filters. Furthermore, its surface mimics that of the surface of human skin. We can evaluate the efficacy of sunscreens more precisely, and can see the population of UV filters on the membrane surface using luminescence. Thus, our new artificial membrane will make it possible to investigate more effective sunscreen formulations.
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