New nursesʼ turnover in Japan was 8．6% in 2020.　While there are various reasons for turnover, one of the main ones is interpersonal relationships in the workplace, and an improvement of new nursesʼ communication skills are important.　This study aims to clarify what kinds of communication skills are required by new nurses, according to nurses in charge of newcomer education.　A semi-structured interview was conducted involving nurses who have experienced at two acute care hospitals for 3-5 years.　The interview content was analyzed using a qualitative inductive method.　Participants were also asked to confirm that there were no discrepancies in the content.　Ethical approval was obtained from the Ethics Committee of Tokushima University （3610-1） and A Hospital （21-2） in Tokushima, Japan.　The average age of eleven participants （1 man and 10 women） was 25．0 years.　The interview time was 22 to 39 （Mean ± SD ; 28．72± 6．05） minutes.　As a result, the following 4 categories were extracted as communication skills required by new nurses : ［Behavior that prioritizes patient safety and comfort］, ［ability to behave close to other personʼs heart］, ［Behave like a new nurse］ and ［Ability to accept the opinions of others］.　In acute phase medical settings, even new nurses require the ［Behavior that prioritizes patient safety and comfort］, including patients.　The educators sought for the new nurses to have the ability to actively express themselves to protect patient safety, and the ability to promote interactions with others within the medical team.　To clarify the communication skills, which are deemed necessary by nurses in charge of newcomer education, it is useful for building interpersonal relationships and developing newcomer education contents in medical settings because to be based on their own experience of newcomer days.

　The purpose of this study was to clarify the current status of oncology certified nurse specialist （OCNS） involvement in cancer genome medicine.　A survey of 235 OCNSs who consented to participate in the study revealed that those involved in cancer genome medicine had a better understanding of hereditary tumors.　Through descriptive content analysis, 8 learning needs were identified in relation to cancer genome medicine.　Among these needs, ［basic knowledge of hereditary tumors and cancer genome medicine］, ［regular acquisition of up-to-date information on genetic medicine］, and ［genetic counseling in actual clinical settings］ revealed no differences between OCNSs involved and not involved in genetic medicine.　On the other hand, ［role of an OCNS in genetic medicine］, ［nursing care for patients and families with hereditary diseases］, ［systems and collaboration to incorporate genetic medicine into organizations］, ［information on genetic medicine for facilities other than urban/designated hospitals］, and ［programmed learning as a systematic approach to genetic medicine provided by academic societies］ differed between the groups in terms of descriptive contents.

　Patients with higher brain dysfunction without motor paralysis are often judged to have no problems with physical function and may have no significant difficulties in daily life during hospitalisation.　Problems may become apparent after discharge from hospital or return to work, especially poor applied activities such as driving a car.　However, the motor characteristics of people with higher brain dysfunction during movement tasks have not been fully clarified, and it is important to assess both the quantitative and the qualitative aspects of movement for work, applied movement and driving.　The purpose of this study was to analyze the relationship between reaction time variability and attention function.　In addition, we analyzed the motion of the lower limb reaction during measurement for examine the motion characteristics.　We enrolled 23 individuals with cognitive dysfunction （CD group） and 56 healthy volunteers （control group）.　Using the reaction measuring device, the time required to lift the right lower limb in response to a light stimulus was measured 20 times in a row.　Therefore, we analyzed the height and acceleration in the vertical direction using a three-dimensional motion analysis system for the reaction of the right lower limb during measurement, as well as the relationship between the reaction time and the Trail Making Test （TMT）.　There was a significant difference in mean reaction time between the two groups, and the CD group showed lower consistency.　The mean reaction time and TMT showed significantly positive correlation.　These results suggest that the reaction time continuously could be one of the tools to evaluate the attention function necessary for the activities of daily living using the lower limbs.　The motion analyses showed their inefficient motion and lower learning effect.　Further studies are necessary to develop accurate criteria using a simple evaluation battery for resuming rehabilitation in individuals with cognitive dysfunction.

　In June 2021, 177Lu-oxodotreotide, a PRRT, was approved by insurance for unresectable or recurrent NETs.　We investigated the efficacy and safety of PRRT in four patients with P-NETs at our hospital.　All patients were confirmed to be positive for somatostatin receptors by using octreoscan.　PRRT treatment was then performed and retrospectively evaluated for efficacy and safety.　PRRT was administered as lutetium oxodotreotide （177Lu） at 7．4 GBq per dose over 30-minutes for up to 1-4 doses at 8-week intervals.　Efficacy was evaluated using RECIST v1. 1. Adverse effects were evaluated by CTCAE （v5．0 JCOG）.

　The mean patient age was 60±12．0 years, and all patients were male.　Three patients had a PS of 0, and one patient had a PS of 1 or higher.　Metastatic organs were the liver in four patients and intra-abdominal lymph nodes in one patient, all of whom were Stage IV.　Three patients underwent transarterial embolization.　177Lu-DOTATOC PRRT was administered every 8 weeks, and a total of four courses were administered in two patients, three courses in one patient, and one course in one patient.　One patient had grade 2 thrombocytopenia after one course, and the second course was administered at a half dose （3．7 GBq）.　The overall response rate （ORR） was 25%, with one PR and two SD.　The median PFS was 9 months （95% Cl, 8-NA）, and the median overall survival from diagnosis was 119 months （95%Cl, 31-NA）.　Adverse events during PRRT included leukopenia in two patients （one G3, one G2）, lymphopenia in one patient （one G3）, thrombocytopenia in two patients （two G2, one G3）, creatinine increase in one patient （one G2）, and skin rash in one patient.

　In conclusion, PRRT is expected to be highly effective and safe compared with conventional therapy for neuroendocrine tumors with unresectable or distant metastases.

　This is, to the best of our knowledge, the first reported case in Japan using eltrombopag for ITP that developed during palliative care for multiple bone metastases of renal cancer.　Platelets decreased to 30，000 while tramadol and etodolac were prescribed as palliative care for multiple bone metastases.　PSL 0．5 mg/kg was started, but no improvement was observed, and eltrombopag 12．5 mg/day was started, and platelets normalized.　During the 8 months when the patientʼs condition deteriorated and oral administration was not possible, there were no noteworthy side effects, and the drug was able to be continued.

　This study aims to identify research trends relationship between nursing and technology.　Original papers titles were searched on the bibliographic database “Igaku Chuo Zasshi （ICHUSHI）” using search keywords “nursing” and “technology” for the past five years.　All analyzes were conducted using the text-mining analysis software KH Coder version 3.　The four top high frequency words were nursing （259）, education （83）, video （66）, and effect （54）.　The overall co-occurrence network showed, technology was associated with simulation education in nursing, online training, audiovisual materials, and robot-assisted communication for older adults with dementia.　In the co-occurrence network with patients, technology was associated with medical safety, transferring bedridden patients, teaching postoperative patients, improving care, risk assessment, and rehabilitation.　In the co-occurrence network with care, technology was associated with the use of equipment in critical care, procedures using audiovisual aids, nursing skills, change in patient perception, training for new employed nurses, and communication with older patients.　These results suggest that in Japan, research is currently being conducted in relation to nursing and technology in nursing education, support for learning nursing skills, medical safety, and nursing aids using robots, etc., to provide high quality care to patients.