The detection rates for colorectal cancers were investigated in 4,127 first-time visits and a total of 2,293 revisits at the Nagano Cancer Center over the last 20 years.
The detection rate for colorectal cancers among first-time visits (7.0%) was significantly higher than those among total revisits (1.2%).
The proportion of colorectal cancers was seen to rise with increasing age, especially over 60 years.
The detection rate for colorectal cancers in the group with subjective symptoms or hereditary relationship among first-timers was higher than that in the group without these factors.
Over half of detected colorectal cancers were early cancers. The proportion of early colorectal cancers increased when examinees underwent endoscopic examination.
It is desirable that people at risk have an examination of the large intestine and that a good system of for endoscopic examination of the large intestine be set up to heighten the detection rate for early colorectal cancers.

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For empiric therapy against bacterial infections, it is most important to select antibiotics on the basis of statistical analyses of drug-resistance of the bacteria isolated in a hospital or a region. In this study, we examined the drug-resistance of Staphylococcus species isolated at Shinshu University Hospital during the 4-year period from 2001 through 2004. Methicillin-resistant strains comprised 37.3% of the total number of Stapylococcus aureus, 73.5% of Stapylococcus epidermidis, 80.9% of Stapylococcus haemolyticus, 41.8% of Stapylococcus capitis, 45.7% of Stapylococcus hominis, 87.9% of Stapylococcus saprophyticus, 40.3% of Stapylococcus lugdunensis, 32.4% of Stapylococcus warneri, and 63.6% of Stapylococcus simulans. Methicillin resistance differed among the departments or the wards, but there was no distinct trend for resistance to increase among each Staphylococcus species. All Staphylococci were susceptible to vancomycine, and almost all were to arbekacin surfate. 65.7% of methicillin-susceptible Stapylococcus aureus and 62.4% of methicillin-susceptible Stapylococcus epidermidis were resistant to penicillin G. The methicillin-resistance rate may be important in selecting antibiotics for the treatment of patients infected with any Staphylococcus species.

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[in Japanese]

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