Sjöogren's syndrome (SS) is thought to be uncommon in children. We have experienced two pediatric cases of SS in the last two years. Case 1 was an 11-year-old boy, and case 2 was an 8-year-old girl. They both had parotid enlargement and arthralgia. Neither was conscious of xerostomia, but case 1 had many caricus teeth and dry lips. The diagnosis of SS was based on histopathological changes in the minor salivary glands. The sialogram of case 2 was compatible with typical SS. In the laboratory studies of these cases, antinuclear antibodies, antiDNA antibodies, rheumatoid factor, anti-SS-A antibodies and hypergammaglobulinemia were observed. Case 2 was positive for anti-SS-B antibodies.
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