Shimane Journal of Medical Science
Online ISSN : 2433-2410
Print ISSN : 0386-5959
Original Article
  • Rina TSUCHIE, Satoko AIKA, Seiji FUKUDA
    2021 年 38 巻 4 号 p. 111-118
    発行日: 2021年
    公開日: 2022/03/11
    ジャーナル フリー HTML
    School non-attendance is often accompanied by declines in self-esteem. The present study investigated factors associated with self-esteem in junior high school students. Self-esteem, “willingness to attend school”, "school life competency" and "consistent lifestyle practice" were evaluated using anonymous questionnaire surveys in 892 students. Self-esteem was quantitated using the scale created by Rosenberg (1965). Association between self-esteem and other variables were analyzed using Spearman’s correlation coefficient. Self-esteem was significantly associated with school life competency (r = 0.501) and consistent lifestyle practices (r = 0.352). Moreover, self-esteem was significantly correlated with willingness to attend school (r = 0.449). Willingness to attend school was also correlated with school life competency (r = 0.476) and consistent lifestyle practices (r = 0.41). These findings imply that improving the consistency of lifestyle practices and enhancing school life competency may increase self-esteem in the students, which will be beneficial to increase students’ willingness to attend school.
  • Yukari TSUBATA, Tomomi AKITA, Ryosuke TANINO, Takamasa HOTTA, Ayano TE ...
    2021 年 38 巻 4 号 p. 119-125
    発行日: 2021年
    公開日: 2022/03/11
    ジャーナル フリー HTML
    The NAD+–sirtuin 1 (SIRT1) pathway is essential for neutrophil differentiation induced by the granulocyte-colony stimulating factor, and thus may contribute to neutropenia observed after cancer chemotherapies. This study aimed to investigate the relationship between neutropenia and indices for the activity of the NAD-SIRT1 pathway, i.e., nicotinamide phosphoribosyltransferase (NAMPT) activity and SIRT1 expression in patients receiving chemotherapy for lung cancer. Blood samples were collected from sixteen patients at the start of chemotherapy, at the nadir, and before the start of the second chemotherapy course. Neutrophil counts, NAMPT activity and SIRT1 expression level were measured. There were no differences observed either in NAMPT activity or in SIRT1 expression level between the cases of grade 3–4 neutropenia and those of grade 0–2 neutropenia though the SIRT1 expression level tended to decrease at the nadir. Further studies are required to elucidate this relationship between post-chemotherapy neutropenia and SIRT1 expression.
Case Report