Journal of The Society of Japanese Women Scientists
Online ISSN : 2186-3776
Print ISSN : 1349-4449
ISSN-L : 1349-4449
Volume 8, Issue 1
Displaying 1-7 of 7 articles from this issue
Review
  • Yoshida Eri
    Article type: Review
    2007 Volume 8 Issue 1 Pages 1-12
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    Micelle formation was studied for “nonamphiphilic” diblock copolymers consisting entirely of solvophilic polymer blocks. Poly(vinylphenol)-block-polystyrene (PVPh-b-PSt) showed no self-assembly in 1,4-dioxane, a nonselective solvent. This nonamphiphilic diblock copolymer formed spherical micelles in the nonselective solvent in the presence of α,ω-diamine such as 1,4-butanediamine, hexamethylenediamine, and ethylenediamine. Steric hindrance at the amino groups and too long chains between the amino groups prevented the copolymer from aggregating. 1H NMR revealed that the micellization occurred by hydrogen bond cross-linking between the PVPh blocks via α,ω-diamine. The critical micelle concentration was determined by the diamine concentration, rather than by the copolymer concentration. The micelles were thermally unstable and dissociated into unimers by increasing the temperature, however, the micelles were completely reconstructed by decreasing the temperature. This dissociation-reconstruction of the micelles was perfectly controlled by the variation in temperature. The self-assembly of the nonamphiphilic copolymers by the α,ω-diamine created a great variety of micelles. The syntheses of crew-cut micelles, random block copolymer micelles, and the micelles with dyes and/or UV absorbents at their cores and/or coronas from the nonamphiphilic copolymers are also described.
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  • ~What Can We Learn from Corneal Transplantation?~
    Junko Hori
    Article type: Review
    2007 Volume 8 Issue 1 Pages 13-18
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    The normal eye possesses immune privilege. When grafted orthotopically to the eye of experimental animals, allogeneic corneas enjoy a relatively high level of acceptance, compared to orthotopic grafts of other types of solid tissue. Each layer of the cornea displays different potentials of alloimmunogenicity or immune privilege. Immunogenicity of the cornea as an allograft resides within its epithelium and stroma, whereas immune privilege arises from endothelium. Corneal endothelium confers immune privilege on the corneal allografts through constitutive expression of CD95L and B7-H1. These molecules induce apoptosis of effector T cells by binding to CD95 and PD-1 expressed on T cells. These two key molecules play a role on peripheral deletion of allo-reactive effector T cells within corneas to maintain immune privilege of corneal allografts. To reduce allogeneic donor epithelium-derived immunogenicity in transplantation, a reconstituted corneal tissue, eliminating the risk of immune rejection, was created. Replacement of donor epithelium with syngeneneic epithelium protects orthotopic corneal allografts from allo-sensitization and rejection even in high risk recipients.
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  • Reiko Fujita
    Article type: Review
    2007 Volume 8 Issue 1 Pages 19-25
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    In the metathesis reaction, the carbon-carbon double or triple bonds are cleaved and the new double or triple bonds are formed again. Since Mo- and Ru-carbene complexes were discovered by Schrock and Grubbs, metathesis reaction have been a useful method in organic syntheses. As the metathesis reaction, 1:ring closing metathesis, 2:cross metathesis, 3:ring opening metathesis, 4:enynemetathesis, 5:diyne metathesis are known.
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Original Paper
  • Sachiko Matsushita, Nobuhito Kurono, Masatsugu Shimomura
    Article type: Original Paper
    2007 Volume 8 Issue 1 Pages 26-32
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    A dissipative process enabled us to prepare hierarchical structures by one-step fabrication. A variety of periodic structures arose spontaneously from volatile oil droplets (organic solvent with amphiphilic polymer) and water droplets (particle water suspension) under high humidity. The resulting material had a honeycomb-like structure (the pore size was 1 mm), packed with functional fine particles, fluorescent polystyrene or titanium dioxide. This process suggested to us that many materials suspended in water, such as viruses (10 -200 nm diameter) and liposomes (20 -50 nm), could self-organize into periodic structures.
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Case Report
  • Yuki Higashi, Hideaki Ohmatsu, Shino Nehashi, Risa Hasegawa, Suguru Yo ...
    Article type: Original Paper
    2007 Volume 8 Issue 1 Pages 33-36
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    A 31 year old woman suffered sudden hemiplegia and headache during the 17th week of her pregnancy. Her diagnosis was cerebral arteriovenous malformation, ruptured in left putamen and into lateral ventricle. Her neurosurgical operation was performed in the 19th week of her pregnancy. Anesthesia was induced using propofol and vecuronium, and maintained with sevoflurane (0.5-1.0%) and nitrous oxide (<50%) in oxygen. During surgery, fetal heart rate was monitored continuously.
    Intense hypotension was not chosen because it may have placed the fetus at risk of intrauterine asphyxia. Ventilation was controlled to maintain PaCO2 between 27 and 35mmHg. Her neurological symptom improved and her baby was delivered vaginally in the 40th gestational week.
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Report
  • - The Result of the Pre-quetionnaire and Interview for Personnnel Supervisor.
    Kaori Sobue
    Article type: Report
    2007 Volume 8 Issue 1 Pages 37-42
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    In this paper, a questionnaire was designed regarding the organization climate for the promotion of balance between work autonomy and work-life obligations. In addition, a preliminary investigation focusing on the persons in charge of personnel affairs was carried out in order to verify the reliability of the questionnaire.
    Organizations targeted by the preliminary investigation were an information systems Company ‘X’ and an autonomous body ‘Y’ As a result of the preliminary investigation a coefficient of reliability of 1 was obtained.
    The organization climate was studied because, although there has been an increase in the introduction rate of flexible work styles, one has not yet been fully applied.
    Changing to a workplace that regards as standard both the acquisition of a flexible work style and a work allocation scheme is thought to contribute to the continued employment of women.
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Report
  • Michi Aratani
    Article type: Report
    2007 Volume 8 Issue 1 Pages 43-55
    Published: 2007
    Released on J-STAGE: October 13, 2011
    JOURNAL FREE ACCESS
    The Society of Japanese Women Scientists (SJWS) has long discussed, since its initial proposal by Prof. M. Suziki (President 1999-2003) and continued by Prof. M. Sasaki (President 2003-2007), introducing a position of Science Communicator, who could play a role in communicating the science world to the public, and how they should be selected and registered.
    Some universities have opened master and doctor courses for science communication under the name of science interpreter and science mediator. The targets of these courses are mainly the young. However, the targets of SJWS discussion are generally of retirement age over sixty years old.
    Culminating from these long and sincere discussions, a new system of SJWS Science Communicator has been created and I was registered as the first SJWS Science Communicator by Prof. N. Oshima (President 2007- ) in June, 2007.
    A case report will be made here on science communication, as a regional collaboration, at a nuclear energy site (Rokkasho, Aomori). This will especially focus on methodology for the purpose of coexistence between the public and scientists in the regional society.
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