Skin Cancer
Online ISSN : 1884-3549
Print ISSN : 0915-3535
ISSN-L : 0915-3535
15 巻 , 1 号
選択された号の論文の18件中1~18を表示しています
  • 石原 和之, 斎田 俊明, 山本 明史
    2000 年 15 巻 1 号 p. 7-14
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    Malignant melanoma even now remains the most fatal type of tumor and number of patient is still increasing year by year. The Prognosis and Statistical Investigation Committee of the Japanese Society for Skin Cancer has periodically conducted a nationwide survey of skin malignancies. We investigated 4, 495 cases of malignant melanoma from 431 fascilities from 1992 to 1998 this time.
    This report was finally summarized in December 1999. It demonstrates the number of the patients by each year and gender.
    It shows that number of patient is actually increasing, and this is more significant in female patients. [Skin Cancer (Japan) 2000; 15: 7-14]
  • 木下 久美, 伴野 純代, 新田 悠紀子, 原 一夫
    2000 年 15 巻 1 号 p. 15-18
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    A Mucoepidermoid Carcinoma is one of salivary glands tumors. A lot of them apear on glandula parotidea. Primary cutaneous Mucoepidermoid Carcinoma is not seen in Japan as far as we can investigate. As a pathological feature, tumor cells are composed of the goblet-like-cell with mucin-containing and squamoid cells. We reported a case of the tumor which was thought with primary cutaneous Mucoepidermoid Carcinoma which had originated in a sweat gland from whole body retrieral and pathology organization study examination. [Skin Cancer (Japan) 2000; 15: 15-18]
  • 岩澤 うつぎ, 神田 弘貴, 大西 泰彦, 大原 國章, 岡崎 篤, 岡本 竹春
    2000 年 15 巻 1 号 p. 19-22
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    Surgical reconstruction of facial squamous cell carcinoma (SCC) is sometimes very difficult depending on the location of the lesion.
    For that reason, non-surgical treatment is preferable in consideration of the quality of life of such patient. We report here a case of SCC on the right naris with 18 months duration, who had been treated with intra-arterial infusion of peplomycin in combination with irradiation. The patient is free of the disease for 14 months after the treatment without any deformity of the nasal contour. [Skin Cancer (Japan) 2000; 15: 19-22]
  • 青木 恵理, 青木 見佳子, 池村 暁子, 五十嵐 司, 鈴木 かやの, 川名 誠司
    2000 年 15 巻 1 号 p. 23-26
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We reported a case who developed three different types of skin cancers: SCC, BCC, and Bowen's disease, on the chronic radiation dermatitis. He had been treated for his tinea pedis et palmaris with radiotherapy in 1940's. It is very ratre that three different types of skin cancers arise in the same patient. This is a second case reported in Japan. [Skin Cancer (Japan) 2000; 15: 23-26]
  • 大井戸 有紀, 嵯峨 賢次, 神保 孝一, 佐々木 公男, 奥村 一彦
    2000 年 15 巻 1 号 p. 27-30
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We reported a case of basal cell nevus syndrome (BCNS) . A 12-year old boy visited us for the examination of numerous skin pits on the palms. He showed hypertelorism, mandibular cyst, calcification of the falx, and mental retardation. Clinical diagnosis of BCNS was made by these findings. Examination of other family members did not reveal palmar pits or any other signs of BCNS. Skin biopsy from the palmar pits showed reduced thickness of the stratum corneum and the presence of basal cell carcinoma in the dermis.
    Chromosome-analysis of peripheral leukocytes revealed the deletion of 9q21.3-22.1. His parents did not show any abnormalities in chromosome-analysis. Very few cases of BCNS have been reported that have basal cell carcinoma on the palms. [Skin Cancer (Japan) 2000; 15: 27-30]
  • 平井 行一郎, 労 力民, 澤井 孝宏, 井戸 敏子, 清原 隆宏, 竹内 章晃, 桑原 広昌, 熊切 正信, 上田 恵一
    2000 年 15 巻 1 号 p. 31-34
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    A case of eccrine epithelioma is reported. A 82-year-old woman had a blackish ulcerated nodule of 5mm×10mm in size on her right lower eyelid. The nodule had increased in size for these three years. She visited our office on March 24, 1998. Since clinical diagnosis was basal cell epithelioma, the lesion was totally excised with more than 5mm margin including orbicularis oculi muscle. Histopathological findings were similar to solid type basal cell epithelioma. But there were some difference; tumor cells connected directly with eccrine glands and were composed of two cell types; dark elongated nuclei with condensed cytoplasm and large clear round uuclei with abundant cytoplasm. Thus our case was suggested to be eccrine epithelioma. [Skin Cancer (Japan) 2000 ;15: 31-34]
  • 天野 正宏, 佐藤 浩信, 長嶺 英宏, 川名 修徳
    2000 年 15 巻 1 号 p. 35-38
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    Dermatofibrosarcoma protuberans (DFSP) tends to relapse locally if the tumor had not be removed totally.
    We report a 57-year-old male with a DFSP on the left inguinal lesion. At 48 years the tumor was removed marginally and misdiagnosed as keoid by histological examinations. 9 years later it recurred under the surgical scar on the same lesion. He had a mental retardation and didn't notice it. Wide excision of the lesion including fascia and skin grafting were perfomed. Histopathologicaly the tumor was composed of uniform spindle-shaped fibroblast-like cells with mild atypia and arranged in a storiform pattern. No recurrece or distant metastasis was seen under the follow up period of 2 years. [Skin Cancer (Japan) 2000; 15: 35-38]
  • 野柳 俊明, 佐藤 俊宏, 高安 進, 浅田 裕司, 倉田 荘太郎, 中城 正夫, 三浦 隆, 吉田 盛治, 横山 繁生
    2000 年 15 巻 1 号 p. 39-43
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    An 84-year-old woman presented with two large tumors on her chest and back, which had been operated twice. The tumor at the first operation was mainly composed of loosely arranged spindle cells with little atypicality and necrosis, mostly in myxomatous ground substance. At the later stage, the tumor cells showed obvious atypicality, including multinucleated giant cells, and were partly arranged in a storiform pattern. Mitotic figures were rarelly observed. Our tentative diagnosis was malignant peripheral nerve sheath tumor. However, neither S-100 protein nor NSE was positive throughout the course. Therefore, we finally diagnosed her condition as myxoid variant of malignant fibrous histiocytoma. She died of local recurrence and distant metastasis to muscle, lung and liver. [Skin Cancer (Japan) 2000; 15: 39-43]
  • 帆足 俊彦, 門野 岳史, 川端 康浩, 菊池 かな子, 玉置 邦彦
    2000 年 15 巻 1 号 p. 45-48
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We have experienced thirty-nine cases of cutaneous malignant melanoma for twelve years from 1987 to 1998 at the Department of Dermatology, University of Tokyo. The number of patients is increasing but this phenomenon is mostly due to increase of in situ patients. We assume that because of the prevalence of knowledge on pigmented lesions, those patients consult us in early stage. [Skin Cancer (Japan) 2000; 15: 45-48]
  • 野本 真由美, 野本 重敏, 伊藤 雅章, 竹之内 辰也, 兼子 泰行
    2000 年 15 巻 1 号 p. 49-52
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We report a case of pedunculated malignant melanoma arising in a medium-sized congenital melanocytic nevus. A 31-year old woman had a rapidly growing pedunculated tumor at the edge of a hairy black macule on her left thigh. The macule was 50×15mm in size at the initial presentation. Pelvic CT scan showed multiple regional node metastases. Wide local excision, therapeutic groin dissection, neo-adjuvant and adjuvant DAV-IFNβ therapy (DTIC, ACNU, VCR, IFNβ) were performed. Histological examination showed congenital melanocytic nevus coexisting with malignant melanoma of pT4aN1M0 stage III, thickness 9mm, level IV. After two courses of adjuvant therapy, multiple liver, brain, and lung metastases were recognized. She died of the disease 3 months after the operation. The present case indicated that even a medium-sized congential melanocytic nevus had a risk for malignant melanoma. [Skin Cancer (Japan) 2000; 15: 49-52]
  • 竹内 章晃, 若原 真美, 豊丸 歩, 平井 行一郎, 清原 隆宏, 桑原 広昌, 労 力民, 熊切 正信
    2000 年 15 巻 1 号 p. 53-56
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We report a case of amelanotic melanoma. A 56-year-old man had noticed a small nodule on his right medial plantar aspect of the foot about one year previously. Although he had tried to remove the nodule by pricking with a pin, it had continued to grow.
    When he visited our hospital an September 2, 1998, the dome-shaped nodule measured 20×18mm. On closer examination, a small pigmented macule was observed in the periphery of the nodule. The right inguinal lymph nodes were swollen.
    We excised the tumor with the presumptive diagnosis of squamous cell carcinoma or eccrine porocarcinoma, since the pigmented macule was faint that the diagnosis of melanoma could not be considered. Wide local excision (2cm margin) and inguinal lymph node biopsy were performed. However, the histopathological diagnosis was malignant melanoma, and lymph node biopsy revealed metastasis of melanoma (pT4aN1M0, Breslow's thickness 4.6mm, Clark level V, Stage III) . Right inguinal lymph node dissection and chemotherapy were added. Electronmicroscopic study revealed many melanosomes in the melanoma cells and confirmed the diagnosis. Amelanotic melanoma should be considered when a red nodule on the foot is examined. [Skin Cancer (Japan) 2000; 15: 53-56]
  • 若杉 正司, 影下 登志郎, 水足 久美子, 小野 友道
    2000 年 15 巻 1 号 p. 57-60
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    Metastasis to the oral cavity from cutaneous melanoma is rare. Fewer than 30 cases of metastatic melanoma to the palatine tonsil have been reported in the literature, and only one of them was from Japan. Metastasis to the tonsil, without afferent lymphatics, suggests hematogenous dissemination and a poor prognosis.
    We present a case of metastatic melanoma restricted to the palatine tonsil. However, in this case, further metastasis has not been recognized in the one and a half years since the tonsillectomy of the metastasic tonsil. We discuss the favorable prognosis from the view point of the antigenic profile of the malenoma cells. [Skin Cancer (Japan) 2000; 15: 57-60]
  • 飛澤 慎一, 和田 隆, 浅野 一弘, 山本 明美, 橋本 博, 飯塚 一
    2000 年 15 巻 1 号 p. 61-65
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We report a case of penile carcinoma of a 67 years old man. A 2cm-sized gradually enlarging penile ulcerative tumor was observed, that was accompanied by scrotal swelling. Histopathology revealed well differentiated squamous cell carcinoma with focal detection of human papilloma virus antigen. The patient was assessed to be clinical stage IV of UICC-TNM classification. Following chemotherapy (BLM 30mg, MTX 70mg, CDDP 50mg), total penectomy was performed and tissue defect was covered with scrotal skin. Bilateral regional lymphadenectomy disclosed two metastatic left inguinal lymph nodes. The patient showed no evidence for local recurrence, but died for lung metastasis. [Skin Cancer (Japan) 2000; 15: 61-65]
  • 杉浦 啓二, 有馬 豪, 牧浦 宗彦, 安達 順子, 清水 善徳, 上田 宏
    2000 年 15 巻 1 号 p. 67-70
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    A 94-year-old man had noticed a swelling on his chest since July 1998. The size of the swelling had increased quickly from February 1999. He had experienced bleeding from the swelling frequently, he had falt difficulty in daily life. He consulted his doctor. His doctor suspected his swelling as a malignant tumor and presented us on July 7, 1999. We excised his swelling completely and examined it by histopathology under an optical and an electron microscope. We diagnosed this case as “Merkel cell carcinoma”. There were no findings of metastasis detected by his whole body. This case is the first report of merkel cell carcinoma developed on the chest of a great aged man. [Skin Cancer (Japan) 2000; 15: 67-70]
  • 南 仁子, 加藤 直樹, 浅野 一弘, 高橋 英俊, 山本 明美, 橋本 喜夫, 吉田 弘, 飯塚 一
    2000 年 15 巻 1 号 p. 71-74
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    A case of cutaneous B cell lymphoma is reported. The patient was a 82-year-old female, who developed multiple indurated plaques and subcutaneous nodules on her trunk during past 6 months. Histopathology of the skin lesion showed diffuse infiltrate of atypical mononuclear cells, that were positive for CD19, CD20, CD10, CD79a, and HLA-DR. Surface immunoglobulin was negative. Gene analyses disclosed that the tumor cells were positive for immunoglobulin gene and T cell receptor δ1 gene rearrangements. We tried total skin electron beam therapy, that resulted in a complete remission of the skin lesion. [Skin Cancer (Japan) 2000; 15: 71-74]
  • 兼森 良和, 野瀬 謙介, 元村 尚嗣
    2000 年 15 巻 1 号 p. 75-78
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    Cutaneous metastasis from the esophagus is relatively rare. A case of 58-year-old male esophageal squamous cell carcinoma with skin metastasis is reported.
    In this case, cutaneous metastasis appeared on the forehead 3 month after resection of stagel esophageal carcinoma. We performed pre-operation punch biopsy, but the origin of squamous cell carcinoma was obscure. After wide resection, we diagnosed it as metastatic skin cancer from its incontinuity to neighboring normal epithelium.
    We suggest that excisional biopsy would be helpful for the differential diagnosis of metastatic skin cancer. [Skin Cancer (Japan) 2000; 15: 75-78]
  • 渡辺 朋美, 小金平 容子, 宇原 久, 河内 繁雄, 斎田 俊明, 小口 正彦
    2000 年 15 巻 1 号 p. 79-84
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We describe a 66-year-old woman with a 3-week history of erythema and bulla on her soles. She had received MACOP-B (methotrexate, doxorubicin, cyclophosphamide, vincristine, predonisolone, bleomycin) therapy for non-Hodgikin's lymphoma. The skin lesion improved after three weeks without stopping the chemotherapy. Histological examination showed many necrotic keratinocytes, irregularly elongated rete ridges, vacuolar alteration in the basal layer, and perivasucular neutrophilic and lymphocytic infiltration in upper demis. These findings suggested a toxic reaction to epidemis induced by MACOP-B therapy. [Skin Cancer (Japan) 2000; 15: 79-84]
  • 橋本 任, 伊藤 文彦, 山内 利浩, 柏木 孝之, 眞鍋 公, 浅野 一弘, 山本 明美, 飯塚 一
    2000 年 15 巻 1 号 p. 85-87
    発行日: 2000/05/10
    公開日: 2010/08/05
    ジャーナル フリー
    We present a case of basal cell carcinoma on the buttock. The patient was a 30-year-old man who noticed a gradually enlarging asymptomatic dark reddish nodule of one year duration on his right buttock.
    Histopathology showed solid type basal cell carcinoma with markedly pigmentladen tumor cells. Surveillance of the literature disclosed 25 Japanese basal cell carcinoma cases of gluteal - perianal location, among which our case was the youngest one. [Skin Cancer (Japan) 2000; 15: 85-87]
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