Histological studies were made on 41 cases of syringoma using hematoxylin-eosin, PAS, silver-impregnation and elastica-van Gieson stained 6-9μ serial sections. Plasticreconstruction models were made from 6 cases.
1. A syringomatous papule consisted of interwining and interconnecting nestsand cysts of epithelial cells surrounded by myoepithelial-like cell
2. A solid epithelial cord was found to traverse between the syringoma and theoverlying epidermis.
3. No direct connections were observed between the syingoma and thepilosebaceous units or the patent eccrine sweat ducts.
4. Intercellular and intracellular secretory canaliculi were found in the wall ofsyringomatous cysts.
5. Syringoma was considerd to represent an eccrine sweat gland hamartoma. The epithelial nests and cysts corresponded with the secretory portion, and the solidcord with the ductal portion of the eccrine sweat gland.
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