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Volume 36, Issue 2
Displaying 1-7 of 7 articles from this issue
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Narimichi TAKEI, Kazuomi UNOSAWA, Shirou MATSUMOTO1999 Volume 36 Issue 2 Pages 98-105
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSPreliminary study for preparation of controlled release particles was carried out by using a fluidized bed coater with a rotary disk. Two types of controlled release particles, particles coated by ethylcellulose film and particles consisting of drug-wax mixture layer, were prepared. Physical properties of controlled release particles prepared by both powder spray method and suspension spray method were measured.
The release rate of drug from the coated particles decreased with increasing thickness of coated film. It was necessary to heat the particles for production of controlled release particles consisting of drug-wax mixture layer. The release behavior of drug was almost similar for those prepared by powder spray method and suspension spray method. Suspension spray method is advantageous in increasing loading volume and drying capacity.View full abstractDownload PDF (2575K) -
Narimichi TAKEI, Kazuomi UNOSAWA, Shirou MATSUMOTO1999 Volume 36 Issue 2 Pages 106-111
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSInfluence of spray and drying process of coating liquid onto the properties of coated films were investigated by using three types of fluidized bed coaters. Top spray method with the conventional fluidized bed coater was ineffective to produce small amounts of coated particles for controlled release of drug. Both smooth surface of coated particles and high adhesion efficiency were obtained by using side spray method in fluidized bed coater with a rotary disk. It is concluded that the concentration of coating materials in the liquid layer on coated particles plays an important role in determining physical properties of the coating film.View full abstractDownload PDF (2304K) -
Hiroyuki IWATA, Hitoshi OHYA, Kaoru MASUDA, Shigehisa ENDOH, Shigeki K ...1999 Volume 36 Issue 2 Pages 112-120
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSWe have recently developed an apparatus for particle shape separation by gyratory motion. In order to study the seperation characteristics, it has been applied to:
1. distinction of particles having relatively small shape difference.
2. preparation of artificial diamond particles as a powdered abrasive according to its crystal morphology.
It has become clear that the efficiency of apparatus for separating spherical particles from non-spherical ones is influenced mainly by the mixed ratio of non-spherical particles in the feed whereas the separation of non-spherical particles could be assessed by making frequency recovery diagrams of desired shape as well as those of undesired one for the gyration radius to be applied.
The apparatus was also successfully applied for the shape classification of powdered abrasives, concentrating crystallized particles in highly nonspherical fractions.View full abstractDownload PDF (4802K) -
Kouichi MIZUKAMI, Kenji YAJIMA, Momoji KUBO, Akira MIYAMOTO1999 Volume 36 Issue 2 Pages 121-129
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSDownload PDF (1133K) -
Masafumi ARAKAWA1999 Volume 36 Issue 2 Pages 130-136
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSDownload PDF (3695K) -
Hiroyasu KOKUBO1999 Volume 36 Issue 2 Pages 149-151
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSDownload PDF (343K) -
Kenji SUZUKI1999 Volume 36 Issue 2 Pages 152-154
Published: February 10, 1999
Released on J-STAGE: April 30, 2010
JOURNAL FREE ACCESSDownload PDF (3763K)
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