粉体工学会誌
Online ISSN : 1883-7239
Print ISSN : 0386-6157
ISSN-L : 0386-6157
57 巻, 11 号
選択された号の論文の3件中1~3を表示しています
論文
  • 紙本 小夏, 中野 裕美
    原稿種別: 論文
    2020 年 57 巻 11 号 p. 572-576
    発行日: 2020/11/10
    公開日: 2020/12/19
    ジャーナル フリー

    In this work, we investigated the crystal structure and photoluminescence (PL) property of Ca2(Si,P)O4:Eu2+ phosphor doped with Al3+ ions. Changes in the crystal structure were evaluated via X-ray diffraction and X-ray absorption fine structure measurements. With increasing concentrations of Al and P ions, the crystal structure transforms from β to α’L phase. The emission color of phosphor changes from green to blue. However, Al ions exerted only a modest effect on the crystal structure and PL property of the material compared with the absence of Al ions.

  • 水永 大輔, 古関 美香, 綿野 哲
    原稿種別: 論文
    2020 年 57 巻 11 号 p. 577-587
    発行日: 2020/11/10
    公開日: 2020/12/19
    ジャーナル フリー

    The purpose of this study is to evaluate the effect of tableting speed on the compression behavior of pharmaceutical powders using an R&D rotary tablet press. Cilostazol, probucol and ibuprofen were selected as model drugs, and they were mixed at a mass concentration of 20% into two base formulations composed of different excipients. The tablets were prepared at two levels of turret rotation speeds of 20 rpm and 60 rpm, and the physical properties of the tablets were evaluated. As a result, placebo tablets and cilostazol tablets had no effect on the tableting speed. However, the compressibility of probucol and ibuprofen tablets decreased and the capping tendency was observed, although the compactibility was not affected. The strain rate sensitivity (SRS) index was obtained from an out-of-die Heckel analysis, which was used to quantitatively evaluate the effect of tableting speed on the compressibility. It was found that the R&D rotary tablet press was possible to evaluate the compressibility and capping tendency by the SRS index.

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  • 田中 智彦, 藤澤 瑛梨, 吉原 章仙, 小西 康裕, 野村 俊之, 近藤 光, 内藤 牧男
    原稿種別: 論文
    2020 年 57 巻 11 号 p. 588-592
    発行日: 2020/11/10
    公開日: 2020/12/19
    ジャーナル フリー

    In this study, we attempted to control the adhesion of lactic acid bacteria by coating hydrophilic titania nanoparticles on a stainless steel substrate to investigate the adhesion of microbial cells to the solid surface in the initial stage of biofilm formation. As a result, it was found that by coating titania nanoparticles on the surface of SUS304, the number of adhered lactic acid bacteria was reduced by about 97%. This is in good agreement with the thermodynamic prediction based on the change in Gibbs free energy when lactic acid bacteria adhered to the SUS substrate. In addition, a single cell probe with a single living lactic acid bacterium was prepared, and direct measurement by atomic force microscopy using the single cell probe revealed that the adhesion force hardly acted between the cell and the SUS substrate modified with titania nanoparticles.

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