日本口腔科学会雑誌
Online ISSN : 2185-0461
Print ISSN : 0029-0297
ISSN-L : 0029-0297
39 巻, 2 号
選択された号の論文の26件中1~26を表示しています
  • Bromodeoxyuridineとその単クローン抗体を用いた算定法
    川辺 良一, 伊藤 健, 海野 智, 藤田 浄秀, 井上 達, 蟹沢 成好
    1990 年 39 巻 2 号 p. 259-266
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    S-phase cells of sarcoma in the maxilla region were detected by means of bromodeoxyuridine and its monoclonal antibody. The labeling index (LI) of malignant fibroushistiocytoma was 13.0% and that of fibrosarcoma was 0.9%, although both tumors were composed of spindle shaped cells. This result revealed a heterogeneity of the growth fraction in sarcomas. Comparing LIs of sarcoma with those of oral squamous cell carcinoma, there was no remarkable difference between them.
  • 有地 淑子, 有地 栄一郎, 森口 信二, 神田 重信
    1990 年 39 巻 2 号 p. 267-277
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Twenty patients with tumorous lesions extending in and into the infratemporal fossa were examined by CT at the Department of Dental Radiology, Kyusyu University Dental Hospital during the period from March, 1985 to September, 1988. They ranged in age from 6 to 75 years (mean, 52.7 years). Eleven were males.
    CT images of these patients were analyzed in detail and the results include:
    1. CT appearances of extension in and into the infratemporal fossa were classified into four types according to the primary site. Further, in cases of tumors originating in the oral cavity the appearances were subclassified into three types.
    2. In 17 of 20 patients (85%), bone involvement adjacent to the infratemporal fossa was detected by CT.
    3. The changes on CT images were considered to reflect clinical signs, such as trismus and sensory changes involving the the fifth nerve (the second and the third division) and others.
  • 手術所見との比較検討
    村上 賢一郎, 瀬上 夏樹, 宮木 克明, 藤村 和磨, 野瀬 将洋, 森家 祥行, 塚本 行雄, 飯塚 忠彦
    1990 年 39 巻 2 号 p. 278-286
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The reliablity and clinical diagnostic value of MR (Magnetic resonance) imaging were evaluated on the basis of the analytical results on surgical findings obtained from temporomandibular joints (TMJ) that had been studied preoperatively with MR imagings.
    In the past 16 months, 14 patients of 17 joints recieved a conventional open surgery or arthroscopic surgery. Preopereative MR imagings were obtained in all joints. 14 out of 17 joints showed a good agreement of predictive positive and negative findings with anterior disk displacement ; six of the 17 joints had disk abnormal morphology ; the remaining 11 joints showed negative findings of perforation. Disagreement of comparative findings was, however, found in four of the 17 joints in both disk morphology and perforation. Neither adhesive and inflammatory findings were predicted using MR imagings.
    Our findings suggest that MR imaging is useful for detection and evaluation of TMJ disk derangements, particularly in disk anterior displacement. Because of its non-irradiative diagnostic capacity, MR imaging has a superior value for diagnosis of uncomplicated internal dernagement of the TMJ. On the contrary, conventional arthrography was thought as an important procedure to detect a finding of intra-articular adhesion or perforation.
  • 第2報 顎関節硬組織の変化について
    杉崎 正志, 鈴木 公仁子, 伊介 昭弘, 田辺 晴康, 加藤 征
    1990 年 39 巻 2 号 p. 287-301
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The greatest care must be paid in discussing a possible cause of temporomandibular joint disorders because there were sexal difference and changes with aging in the masticatory structure as described in Part 1. The purpose of this part is to clarify the sexal difference and changes with aging of the temporomandibular bone surface and to elucidate the effect of masitication on the temporomandibular bone changes.
    Results: Bone changes frequently occured at the lateral side of the condyle, lateral and central sides of the eminence and in a central part of the anterior slope of the eminence. Old females showed a higher score of changing than males with a significant difference between them. Molar or posterior tooth defect had an influence on the condyle and temporal component changes in the young. Progressed attrition with aging influenced on the changes of the temporal component bone surface in males. The temporomandibular joint in males showed a relative stability from the end of growth period to 30 years of age, but females showed no stability throughout the life including growth period. Edentulous changes were caused by aging and loss of teeth so long as this study concened.
  • 第1報 線的計測
    杉崎 正志, 伊介 昭弘, 田辺 晴康, 加藤 征
    1990 年 39 巻 2 号 p. 302-315
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    96 mandibular fossae of Japanese dry skulls were investigated with a threedimensional measuring apparatus. The results were as follows:
    1. On the average, the deepest point of the fossa was 0.921 mm superior to Frankfurt horizontal plane, 12.989 mm anterior to the point from Porion and 48.856 mm exterior to the mid sagital plane.
    2. Similarly the articular tubercle was 7.779 mm inferior, 22.142 mm anterior and 58.643 mm exterior respectively.
    3. The medial glenoid tubercle was 7.799 mm inferior, 13.191 mm anterior and 38.103 mm exterior respectively.
    4. The post glenoid tubercle was 5.289 mm inferior, 6.676 mm anterior and 52.694 mm exterior respectively.
    5. The fossa was an isosceles triangle in shape from the cranial basal view.
    6. The side lengths of the triangle (the fossa) differed significantly between males and females except the lateral side length.
    7. According to Angle's classification, a significant difference in value was observed among the three points, i. e. the deepest, the articular tubercle, and the medial glenoid tubercle points.
    8. The deepest and eminence area were classified to three types from anterior and cranial basal views: angled type, concave type and flat type. According to this findings, the ratio of angled to concave to flat types in the deepest area was 2: 3: 7. The ratio of three types in eminence form was almost equal. From frontal view, the form of the deepest area was almost concave type, concave type accounted for 70 percent of all.
  • 古木 良彦, 谷本 啓二, 和田 卓郎
    1990 年 39 巻 2 号 p. 316-323
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The aim of this study was to elucidate the changes of swallowing behavior in a patient treated with partial maxillectomy before and after operation. Cineradiographic examination was carried out before and 9 months (with no obtulator for palatal defect), 10 months (with an obtulator for 2 weeks) and 15 months after operation (with an obtulator for 6 months). The swallowing transit time and the movement of oral structure during the oral and pharyngeal stages were analyzed.
    The results were as follows ;
    1. Without an obtulator:
    The squeezing movement of the tongue disappeared and the dorsum of tongue became flattened and declined posteriorly. As a result, the contrast medium seemed to fall down along the tongue slope by the aid of gravity. In the posterior wall of oropharynx, the Passavant's ridge which was not observed before operation appeared and the soft palate movement was reduced slightly.
    2. After using an obutulator:
    The squeezing movement of the tongue was observed again and the flattening of the tongue disappeared. With the obtulator for 2 weeks, the swallowing pattern became similar to that of before operation. Six months later, the movement of soft palate increased nearly the same as that of before operation. The Passavant's ridge still remained.
  • 上皮細胞の分化と基底膜形成機序について
    中井 康寿, 上田 実, 金田 敏郎
    1990 年 39 巻 2 号 p. 324-335
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    A mucosal tissue model was prepared in vitro by using epithelial cells and fibroblasts from rabbit and human oral mucosa and collagen gel. The differentiation process of epithelial cells and formation of basement membrane in this rabbit mucosal model were observed by light and electron microscopes. Also, the forming process of basement membrane was immunohistochemically observed by staining of laminin in the human mucosal model.
    1. The mucosal tissue model was prepared by culturing epithelial cells on the surface of submucosal tissue model, which had been made of fibroblasts and hydrated collagen.
    2. By light and electron microscopical examinations, a monolayer of epithelial cells was seen on the submucosal tissue model on the 7 th day of culture. Three epithelial cell layers were seen on the 14 th day of culture. And the first stage of epithelial differentiation was observed in these cells. A formation of hemidesmosome at the border of epithelial layer and submucosal tissue model was observed on the 21 th day of culture. The multilayered epithelial cells resembled the normal epithelium, in which complete differentiation of epithelial cells was found ultrastructurally on the 28 th day of culture. At the basement membrane region, hemidesmosome, lamina lucida, lamina densa and anchoring fibrils were seen.
    3. By immunohistochemical examinations, laminin was not observed in the boundary region between epithelium and connective tissue on the 7 th day of culture. However, laminin was linearly observed at the border of them on the 28 th day of culture.
    4. In conclusion, the mucosal tissue model achieved a complete differentiation of epithelial cells and simulated a structure of basement membrane on the 28 th day of culture.
  • 佐藤 方信, 佐島 三重子, 畠山 節子, 大津 匡志, 鈴木 鍾美
    1990 年 39 巻 2 号 p. 336-342
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The tissues from the anterior, middle and posterior regions of the tongue obtained from autopsy cases were examined histologically. The incidence of abnormal epithelial changes in these regions was evaluated in relation to the patient's age. Several keratin proteins were immunohistochemically demonstrated in the epithelium showing some histological anomalies.
    The following results were obtained:
    1. Atrophy of the mucosal epithelium was seen in the posterior region in most cases. Such cases tended to increase with the advanced patient's age.
    2. Elongation of the epithelial ridge and epithelial hyperplasia were more frequently observed on the left and right lateral portions of the middle region of the tongue. The elongated epithelial ridge was mostly found in the cases of 50 years old or more.
    3. Disorderly arranged basal cells generally existed together with the epithelial hyperplasia or the elongated epithelial ridge. If classified by age, the incidence was high in the thirties and the fourties.
    4. Abnormal localization of keratin proteins was seen in the atrophic epithelium, elongated epithelial ridge, hyperplastic and dysplastic epithelium. This suggests an abnormal change in the differentiation mechanism of epithelial cells.
    5. Since the left and right lateral portions of the middle region of the tongue proved to show a higher incidence of tongue cancer, it appears that such abnormal epithelial changes may be closely related to the histogenesis of tongue cancer.
  • 桜井 一成
    1990 年 39 巻 2 号 p. 343-365
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Some types of leukoplakia in the oral mucosa have a malignant disposition. However, the carcinogenetic process is not clearly understood and the histopathological criteria used for their assessement vary.
    A hundred fifteen cases of leukoplakia and their related white lesions in human oral mucosa were histocytochemically examined by a biotinyl lectin and avidin-horseradish peroxidase (HRP)-labeling method to determine whether the lectin-binding capacity would serve as an index for the malignant transformation of these lesions.
    Eight biotinyl lectins including, PNA, GS-I, DBA, BPA, W GA, ConA, UEA-I and LPA were used to examine the binding pattern in cells and tissues in individual lesions.
    Mucosal lesions were histologically divided according to the developmental stages such as normal, dysplasia (mild, moderate, severe), early invasive carcinoma and invasive carcinoma, based on the severity of the lesions. Each lectin showed a distinct binding pattern at various sites in the epithelial layer and cells with advanced stages as the lesions proceeded from benign to malignant. For example, severe dysplasia and early invasive ;squamous cell carcinoma could be differentiated when the binding patterns of three lectins, PNA, GS-I and LPA, were combined.
    It thus appears reasonable to conclude that lectins may not only serve as a good marker of the malignant transformation of white lesions but also reflect the actual state of neoplastic and malignant transformations of the lesions. Lectins may also be used for the histopathological diagnosis of white lesions, and thus of use in the clinical practice such as the determination of surgical margins in operation.
  • 菊地 白, 安蒜 昌宏, 児野 喜穂
    1990 年 39 巻 2 号 p. 366-376
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Immunotherapy with Sizofilan has been used for treating oral cancers in our department since 1987. Eight cases were observed in this study. Immunological investigations revealed the following findings: 1) Lymphocytes decreased after operation plus radioand chemotherapy, but the return to the pretreatment level could been achieved 2-3 months after operation. 2) The values of OKT 3 and 4 well corresponded to the lymphocyte count at each stage. 3) The values of OKT 8 indicated low level in controlled cases, on the other side comparatively high level in un-controlled cases at each stage. For the reasons stated abve, Sizofilan contributes to promote active immunological mechanisms of patients concerning therapeutic procedure against cancer.
  • 第2報 顎運動時について
    高木 律男
    1990 年 39 巻 2 号 p. 377-388
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The microvascular architecture in the retrodiscal region of the TMJ was examinedat the opening, protrusive and lateral jaw positions and compared with the resting position in adult rabbits using a vascular casting/scanning electron microscopic method.
    The retrodiscal region includes two distinct vascular networks, one lies mainly posterior to the superior articular space and is cap-shaped at rest, the other lies posterior and superior to the inferior articular space and is plate-shaped at rest. With the anterior-inferior movement of the condyle and articular disc at the opening, protrusive and non-worked lateral jaw positions, the blood vessels in the retrodiscal region were dilated and the cap-shaped and plateshaped vascular networks were stretched. The dilated vessels are thought attributable to the negative pressure generated by mandibular movements.
    The blood vessels in the plate-shaped network were occluded when the jaw was opened, closed and protruded. In the lateral jaw position, the plate-shaped network was occluded by the posterior-superior movement of the condyle on the working side but remained unoccluded on the non-working side. Occlusion of blood vessels in the cap-shaped network was found on the working side of the lateral jaw position. It is suggested that the blood vessels in the plate-shaped and cap-shaped networks play a role in absorbing the pressure caused by the condylar movement.
  • 小野 和宏
    1990 年 39 巻 2 号 p. 389-404
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Effects of non-painful and painful mechanical stimulations of tooth and gingiva on the gingival blood flow were studied by using a laser Doppler flowmeter in ten healthy subjects.
    The findings obtained were as follows:
    1. Repetitive mechanical stimulation of tooth and gingiva produced an increase in the gingival blood flow. Painful stimulation elicited a marked flow increase. Sub-painful stimulation also induced a less marked but constant increase in the blood flow. The response was abolished after local anaesthesia at the stimulated site.
    2. The threshold of stimulation for the upper central incisor was 0.3-1.8 kg. The corresponding values for the labial gingiva and palatal mucosa were 100-370 g/cm2 and 220-410g/cm2, respectively.
    3. The increase in the gingival blood flow elicited by the ipsilateral stimulation was greater than that elicited by the contralateral stimulation. Contrary to painful stimulation, non-painful stimulation of tooth and gingiva induced no increase in the cutaneous blood flow of the cheek and hand.
    4. Gingival blood flow increased following voluntary rhythmic biting of an acrylic resin block and chewing of a dried cuttlefish.
    These results suggest that a mechanical stimulation of tooth and gingiva during oral functions such as mastication may induce an increase in the gingival blood flow.
  • 大澤 毅晃
    1990 年 39 巻 2 号 p. 405-424
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    This study was carried out to evaluate the speech intelligibility following prosthetic or surgical obturation of surgically acquired maxillary defects in thirteen patients. Defects were restored with placement of maxillary obturator prosthesis in eleven of these patients; in three cases of them, prosthesis was applied in combination with a speech appliance. In two cases, maxillary defects were immediately reconstructed with free forearm flap surgery and speech appliances were applied postoperatively.
    Speech intelligibility was measured by a standardized Japanese speech intelligibility test, and oral-nasal separation and velopharyngeal function were evaluated by use of a specially designed spirometer and endoscope and of cephalometric radiography with contrast media, respectively.
    The following results were obtained:
    1. The patients with stable prosthesis, and with the resected portions of the maxilla confined to the bony palate, achieved sufficient restoration in speech intelligibility similar to their preoperative levels.
    2. The patients in whom the resected portions extended into the anterior portion of the soft palate achieved adequate improvement in speech following placement of a speech appliance in combination with maxillary obturator prostheses.
    3. Of the patients with resected portions extending into the posterior end of the soft palate, those who had received an immediate reconstruction achieved high intelligibility scores while those without surgical reconstruction scored less well.
  • 杉本 裕史
    1990 年 39 巻 2 号 p. 425-437
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    To determine the occlusal pressure bearing capacity of Apatite 2-Piece Implant, an implant of this type was invested into the jaw of monkeys and biting raise was attempted so that excessive occlusal pressure might be loaed along the longitudinal direction. At 1 week, 2 weeks and 1 month after biting raise, changes which occured in tissues surrounding the implant of M2 were studied histopathologically with following results.
    1) In the alveolar wall of a tooth adjacent to the A2P-Implant and in the area near the cortex of the buccal side and the lingual side, much new bone was observed. However, in the area remote to the A2P-Implant less new bone was formed.
    2) In the area around A2P-Implant where much new bone was observed, lamellated bone was rich in the surface of bony tissues. The area in which formation of lamellated bone was observed was narrow in width at 1 week and 2 weeks after biting raise, but the width of this area became greater at 1 month.
    3) Osteoblastocytes and osteoid seem in the trabecular surface were observed in the deeper layer and the base at 1 week after biting raise and in almost whole area at 2 weeks. However, at 1 month after biting raise, the area which showed osteoblastocytes and osteoid became smaller and changes in response to biting raise almost disappeared with only dynamically acquired trabecula left.
    4) No necrosis or bone resorption of surrounding tissues caused by excessive occlusal pressure due to the biting raise was observed.
    5) From these findings it was indicated that the A2P-Implant and its surrounding bony tissues can sufficiently tolerate even in the presence of excessive occlusal pressure.
  • 特に, 球状上顎嚢胞と鼻口蓋嚢胞について
    鈴木 貢, 白戸 真実, 下舘 洋美, 三尾 和久, 小林 恒
    1990 年 39 巻 2 号 p. 438-449
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    This investigation included 17 cases of globulomaxillary cyst and nasopalatine cyst. By their clinical findings and examinations, the pathogenic factor was examined. The following results were obtained;
    1) It was found by MRI that globulomaxillary cysts appeared in the incisive suture region of the maxilla and nasopalatine cysts appered in the center of the incisive canal.
    2) It was presumed that globulomaxillary cysts may originate in the aberrant epithelial tissue to the bone incisive suture region of the maxilla and that the primordium of nasopalatine cyst is an epithelial tissue during the developmental period of incisive canal.
    3) In the infected fluid of developmental cyst, it was found that the value of Pco2decreased, the concentration of LOO-radical measured at g=2.005 increased and lipid peroxidation occurred. Accordingly, it was proved that an inflammatory process is one of the pathogenic factors.
  • 実験的担癌体末梢血リンパ球による検討
    坂井 広也
    1990 年 39 巻 2 号 p. 450-458
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The incidence of spontaneous and mitomycin C (MMC)-induced sister chromatid exchange (SCE) was investigated in peripheral lymphocytes of 7 male golden hamsters bearing transplanted squamous cell carcinoma in the cheek pouch and 7 normal controls. The results are summarized as follows.
    1. Both tumor bearing and control groups were sensitive to SCE induction by MMC.
    2. The mean incidence of spontaneous SCE in the tumor bearing group (7.65±0.78) was significantly higher (Wilcoxon, P<0.005) than that in the control group (5.72±0.41).
    3. The mean incidence of SCE induction by 5 ng/ml of MMC was 16.0 ±1.73 in the tumor bearing group and 12.29±1.38 in the controls. The corresponding values at a dose of 10 ng/ml of MMC were 20.39±1.38 and 17.36±1.14, respectively. The incidence of SCE in the tumor bearing group was significantly higher (P<0.005) than that in the control group at either dose of MMC.
    The results suggest that peripheral lymphocytes of the golden hamster are useful for investigating SCE, and that SCE could be used as a preclinical parameter to predict the presence of malignant tumor.
  • 特にLarge granular lymphocyteについて
    篠田 鉄郎, 藤内 祝, 金田 敏郎
    1990 年 39 巻 2 号 p. 459-465
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The distribution and ultrastructure of cells defined by MRC OX8 monoclonal antibodies was immunocytochemically investigated in rat submandibular lymph nodes (LN) after stimulation of natural killer (NK) activity by OK-432, a biological response modifier (BRM). In the non-stimulated LN, OX8+ cells were present in the paracortex and virtually absent in the cortical area. We observed OX8+ cells in the cortical area in the stimulated LN clustered within the germinal center. These OX8+ cells consisted of both MRC OX19+ and OX19-phenotypes. Immunoelectron microscopically, some of these OX8+ cells had intracytoplasmic granules characterized by large granular lymphocytes (LGL). Furthermore, various types of granules arising from multivesicular bodies were found. Since it has been reported that NK activity is closely associated with LGL and OX8 reacts with the majority of rat NK cells, the present results suggest that NK cells may be differentiated or matured in the germinal center of LN.
  • 第1報 リンパ節病変について
    野谷 健一, 牧野 修治郎, 福田 博
    1990 年 39 巻 2 号 p. 466-475
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    We reviewed 355 cases of cervical lymphadenopathy diagnosed during the period from 1967 to 1987. When these cases were divided into two groups, reactive lymphadenopathy and tumorous lymphadenopathy, the former was encountered in 296 cases and the latter in 32 cases.
    The primary disease of reactive lymphadenopathy included: 128 odontogenic infections, 114 unknown origin, 19 tubercloses, 13 pharyngitises, 6 mucositises, 7 infectious mononucleosises, 3 hyperplasias, and 1 each of toxoplasmosis, drug allergy and others.
    Tumorous lymphadenopathy was the cause of 17 malignant lymphomas (contained 6 Hodgikin's diseases) and 15 metastatic diseases. The primary site of metastasis was the oral cavity in 4 cases, oropharynx in 3, and lip and others in 1 each. The pathological diagnosis was squamous cell carcinoma in 9, malignant melanoma in 2 and others.
    Clinical appearance of the enlarged lymph node due to various diseases was investigated.
  • 金田 敏郎, 成瀬 文和, 沢木 佳弘, 藤内 祝, 上田 実, 水谷 英樹
    1990 年 39 巻 2 号 p. 476-486
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Both analysis and examination were made on 95 cases of traumatic mid-third facial fracture hospitalized in the Department of Oral Surgery, Nagoya University Hospital during the past 20 years from 1967 to 1987.
    Sex ratio of the fracture was 5: 1 with a higher incidence in males ; by age distribution, the twenties, thirties and even the forties showed a high incidence. The cause of injury was a traffic accident in most cases according to the reports already published. Computed tomogram (CT) proved to be useful for diagnosis of the fracture site ; it enabled us to make an easy and positive diagnosis of the fracture site which could not be detected by conventional radiographic findings. Recent complicated and strong external forces led to splintered fractures in all cases in discordance with the classification of fractures by Le Fort. We believe that an open reduction should be performed in these patients and especially those who have a fracture of the orbital floor complicated with diplopia need an early operation. Screw fixation by interosseous wiring and/or titan metal plate is effective for bone fixation, and more, its combination with Meidai external pin fixation system proved to be more useful.
  • 丹 千昭, 三宮 慶邦, 丸岡 靖史, 安藤 智博, 扇内 秀樹, 安彦 善裕, 下野 正基
    1990 年 39 巻 2 号 p. 487-493
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Malignant odontogenic tumor is an extremely rare lesion. In particular, ameloblastic carcinoma which has recently been proposed is regarded as an ameloblastoma exhibiting cytological and histophathological malignancies without metastases. We describe a case of ameloblastic carcinoma appearing in the left mandible of a 52-year-old woman. The classification of malignant odontogenic tumors and the importance of differential diagnosis for this lesion are discussed.
  • 小野 繁, 石井 多加代, 青木 紀昭, 青木 伸二郎, 川辺 良一
    1990 年 39 巻 2 号 p. 494-498
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    We experienced a rare case of metastatic skin cancer of unknown origin, which appeared in the right neck and cheek. This case manifested sudden edema and redness, as if an inflammatory process was present. An inflammatory metastatic growth was seen. Because of these clinical manifestaitions, a correct diagnosis could not be made until biopsy was attempted.
    The most common clinical presentation of cutaneous metastasis is multiple nodules that appear suddenly in one area of the body. An inflammatory carcinoma usually implicates an advanced stage of malignant disease. Also in this case, the patient survived only two months after appearance of the skin tumors.
    In this paper we reviewed several reports on this subject, and presented our experience with this rare case.
  • 島原 政司, 小野 克己, 豊島 敦哉, 紺田 敏之, 寺井 陽彦, 岸本 幸彦, 橋口 範弘, 南 理代
    1990 年 39 巻 2 号 p. 499-511
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    A combination therapy of tolperisone-HCL, a hypomyotonic agent, with SSP was performed in 49 patients with temporomandibular arthrosis excluding those who were caused by overt organic lesion, abnormal occlusion, or prosthesis. This conservative treatment consisted of medication and physiotherapy for relieving pain and myotony, was adopted as a treatment method of our first choice.
    Results:
    (1) A high improvement rate was obtained in the following symptoms: arthralgia during exercise, autochthonous arthralgia, tenderness in the joint and muscles, trismus and unpleasantness.
    (2) The effect was not favorable in patients with simple articular noise.
    (3) The treatment was effective on type I arthrosis according to the classification of the Japanese Society for Temporomandibular Joint.
    (4) The overall rating of effectiveness was: markedly effective in 16.3 %, effective in 40.8 %, slightly effective in 28.6 %, and no effect in 14.3 %.
    (5) Adverse side-effects probably related to the agent adminstered were observed in 6 out of 49 cases (12.2 %). however, these manifestations were all slight in degree, requiring no withdrawal of the drug in all cases.
    (6) No side effects probably due to SSP therapy were found. On the basis of these findings, it is considered that the combined administration of tolperisone-HCl as medication and SSP as physiotherapy was effective and highly safe for relieving the symptoms of temporomandibular arthrosis caused by myotony.
  • 廣瀬 孝基, 江幡 晃治, 粕谷 幸生, 林 康司, 宇佐美 雄司, 金田 敏郎
    1990 年 39 巻 2 号 p. 512-516
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The odontogenic keratocyst is well known its recurrent tendency caused by a keratinized epithelial lining. A 10 year-old boy with two gigantic odontogenic keratocysts in the mandible (from 6 mesial to 4 mesial, from 6 to left ramus) was admitted in our department. The cysts were opened under general anesthesia but were not extirpated, considering a risk of suppressed growth and development of the mandibular bone. Pathological diagnosis was odontogenic keratocyst, and the postoperative course was entirely good without recurrence.
  • 山口 透, 藤崎 誠, 大久保 章朗, 田畑 雅士, 石沢 新, 山下 佐英
    1990 年 39 巻 2 号 p. 517-526
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The incidence of sialolithiasis in the parotid gland is usually lower than that of the submandibular salivary gland. We have recently encountered two cases of parotid sialolithiasis.
    Case 1 (a 47-year-old man); Three calculi were located in the right intermediate region. Surgical operation was performed through extraoral approach.
    Case 2 (a 48-year-old man); Twenty calculi located in the right extraglandular duct were removed through intraoral approach.
    A statistical analysis on 97 cases reported in the Japanese literature was attempted and the results were discussed briefly.
  • 大沢 幸世, 早津 良和, 篠崎 文彦
    1990 年 39 巻 2 号 p. 527-531
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Hemangiomas are often congenitally formed and do not tend to increase in size very much. They are not true tumors, but vascular malformation or “hamartoma” is found in the head or neck region. Recently we treated a hemangioma which had many phlebolithiasis suspected salivary calculi in the left submandibular gland.
    A 17-year-old boy was referred to our clinic. He had mild diffuse painless swelling' in the left submandibular region. Swelling appeared after eating and disappeared in a few hours in a repeated manner. In pantomography three circular shadows were found in the left submandibular region, ranged from millet to bean in size. Sialography suggested calcification in the gland. We suspected sialolithiasis of the left submandibular gland. Under general anesthesia the region was opened. A dark red hemangioma as big as a walnut was found behind the submandibular gland and then removed. The histopathological diagnosis was venous hemangioma with five phleboliths of which sizes ranged from 3 to 7 mm in diameter. Seven months after there was no recurrence.
  • 自験例と文献的考察
    宇佐美 雄司, 田口 望, 上田 実, 藤内 祝, 水谷 英樹, 金田 敏郎
    1990 年 39 巻 2 号 p. 532-538
    発行日: 1990/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Parosteal osteosarcoma is a rarely encountered variety of osteosarcoma which is differentiated from a common intramedullary osteosarcoma. The clinical appearance and pathological observations often indicate a benign tumor. We reported on a case of mandibular parosteal osteosarcoma and reviewed the literature concerned in this article. A 61-year-old woman was affected by painless swelling of the alveolar bone adjacent to a left lower molar. The first and second biopsies indicated osteoma and reactive bone formation respectively. As the tumor enlarged rapidly, marginal resection of the mandible was performed. Tumor recurred on the left mandibular condyle in the 9 th month following surgery. She then underwent hemimandiblectomy and reconstruction with an alumina ceramic jaw. The tumor was finaly diagnosed as a parosteal osteosarcoma by its appearance and radiographic findings. Her postoperative course has been uneventful to date. It is concluded that wide excision is recommended for such cases.
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