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Volume 39, Issue 3
Displaying 1-25 of 25 articles from this issue
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Part 3: Shape of Condylar HeadMasashi SUGISAKI, Kuniko SUZUKI, Akihiro IKAI, Haruyasu TANABE, Susumu ...1990 Volume 39 Issue 3 Pages 539-550
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSVariation in condylar shape has been noted, but the diagnostic importance of specific condylar shapes in remodeling and arthrosis and clinical meanings of condylar shapes needs to be clarified. We investigated 908 condyle of 454 Japanese dry skulls, temporomandibular joint bone surface change and masticatry system. Convex type displayed high incidence in all age-classes, high incidence of symmetrical shape and lowest surface changes scores. These data mean that convex type is best suited for the human masticatory system. Flat type condyle indicated powerful bite force and major scores of condyle changes. This may be showed that flat type are resulted by remodeling with some part. Round type were seen frequently in Angle's class DI more than in the other four shapes. This type had weak bite force, lower incidence of symmetrical shape and high surface changes scores. They had significant difference on Chi-square distribution with aging and had not stability of condylar shape in a life. Angled type indicated powerful bite force but minor condyle change scores. This may mean that angled type had very stable shape. Other types showed lower incidence of symmetrical shape, invasive remodeling or arthrosis and significant difference on Chi-square distribution with aging. The causes on bone surface changes were differed with each shapes. We decided that some causes of flat and round forming were remolding, because flat type and round type showed singularity of appearance of bone surface changes area. But we could not decide its distribution.View full abstractDownload PDF (1271K) -
Part II, Differential of Subset with T LymphocyteRyuzo KATO, Etsuhide YAMAMOTO, Eisuke FUJIMOTO1990 Volume 39 Issue 3 Pages 551-556
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSAntitumor activity of Propionibacterium acnes strain KT-28, an isolate from oral cavity, was examined by using mice inoculated with Meth A cells. Immunological examination revealed that Lyt2+T cells increased significantly but L3T4+T cells did not, when the protease-treated ultrasonic sediment preparation was injected into mice with the solid type tumor of Meth A cells. Furthermore, it was suggested that the antitumor activity might be related to immune system.View full abstractDownload PDF (712K) -
Yoshihiro SAWAKI, Fumikazu NARUSE, Minoru UEDA, Iwai TOHNAI, Hideki MI ...1990 Volume 39 Issue 3 Pages 557-566
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe purpose of this study is to investigate the features of maxillofacial bone fractures due to sports accidents, because few detailed cases in the literature could be found.
Sixty patients hospitalized for treatment in the department of oral surgery, Nagoya University Hospital in the period 1967-1988, were analysed.
The incidence of this group among all facial bone fractures was 14.7 %, and sex ratio ofonset was 14: 1 with male predominance. By age distribution, the highest occurence was in the 20-29 age group. The incidences of soft tissue traumas complicated with fractures and multiple fractures by sports accidents were less than by other causes.
In conclusion it appears that sports-related maxillofacial fractures are less serious than the injuries due to other causes.
For prevention of sports injuries it is necessary to investigate the individual factors of every fractures and the concept of “Sports Dentistry” must be established.View full abstractDownload PDF (1004K) -
Kiyoshi YOSHIDA, Junichi TANAKA, Mitsugu SUZUKI1990 Volume 39 Issue 3 Pages 567-573
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSSome prostaglandins are known to accelerate tumor growth by means of weakening the immunity of the host but others are known to suppress the tumor. In oral cancer cases, tumor-infiltration into the bone is an important factor in progress and therapy of the cancer because oral mucosa is close to bones such as mandible and maxilla. Not enough reserch has been done with regard to relation between arachidonic metabolites and tumorinfiltration into the bone.
In this research paper we analyse 10 oral cancer tissues and 5 tumor-infiltrated bones to find what metabolites accelerate or suppress tumor growth and what metabolites accelerate tumor-infiltration into the bone or osteo-absorpsion. W e use high performance liquid chromatography systems to analyse tumors, and infrared spectroscopic analysis systems with Fourier transformation for tumor-infiltrated bone, to get some knowledge as below. Possibly tissue γ-GTP has metabolized them before experiment, so LTC4 and E4 are seldom calculated. 15-HETE and PGD2 tend to highly calculated in metastatic or low differentiated carcinoma. In IR spectrum of tumor-infiltrated bone, peaks ν4 and ν'4 are flattened, which reflect osteoabsorption, and the difference between spectrum of tumor-infiltrated bone and that of contrasted normal bone shows 1719 cm-1 peak and 975 cm-1 peak. The former may reflect PGA1, and the latter PGB1 ejects or PGD. As the tumor which the most remarkable osteoabsorption contains much 6-keto PGF1α, PGI2 may be one of the elements of osteo-absorption produced in cancer.View full abstractDownload PDF (675K) -
Simultaneous Analysis of Linguapalatal Contact Patterns and Jaw MovementsChiharu MATSUDA1990 Volume 39 Issue 3 Pages 574-604
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThis study was carried out to clarify the relationship between articulation and patterns of tongue and jaw movement in mandibulectomy patients.
Articulatory movement was synchronously analysed using high-speed 16 mm cinematography and dynamic palatography in twenty mandibulectomy patients and five normal adults. The relationship between articulatory movement analysed and the scores of auditory tests was investigated.
The results obtained were as follows: As could be expected, patients with slight tongue resections and who exhibited slight mandibular displacements at rest and during vertical jaw movement showed near normal linguapalatal contact and only minor distortions in articulation, while those with extensive tongue resections showed severely abnormal linguapalatal contact patterns and severe distortions in articulation. However, patients exhibiting abnormal mandibular movement, even though tongue resection may have been slight, also showed abnormal linguapalatal contact patterns and severe distortions in articulation. The types of abnormal mandibular movement in which these results occurred were: an abnormally large deviation of the mandible at the highest position, abnormally large horizontal deviation of the mandible during articulation, abnormally long distance or fast peak velocity of mandibular movement, and unusual horizontal deviation of the mandible at rest associated with oblique motion during linguapalatal contact. These results suggest that abnormal mandibular movement is one of the causes of articulation disorders follwing mandibulectomy and therefore preserving musculature and minimizing the formation of the scar tissue surrounding the remaining mandible may help to minimize acquired articulation disorders following mandibulectomy.View full abstractDownload PDF (2874K) -
Osamu MIYAMOTO1990 Volume 39 Issue 3 Pages 605-631
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSArticulatory movement was synchronously analyzed using dynamic palatography and high speed 16 mm cinematography in twenty-four mandibular prognathism patients and six normal adults during production of /asa/, /ata/, /ara/ and /apa/.
The results obtained from the mandibular prognatism patients were as follows:
1. The most commonly distorted consonants were /s/ and /p/ followed by /t/ and /r/ sounds in that order. Some of the distorted /s/ consonants were perceived as interdental and some of the distorted /t/ consonants were perceived as either interdental or palatalized.
2. The grade of distortion of /s/ consonants perceived as interdental correlated with the severity of overj et and openbite.
3. Patients with minor speech distortions exhibited the following compensatory speech mechanisms:
(a) Near normal linguapalatal contact patterns for /s/ were obtained by moving the location of oral narrow groove backward as evidenced by posterior displacement of the mandible.
(b) Most patients with minor speech distortions achieved anterior linguapalatal contacts for the /t/ sound by posterior displacement of the mandible although some with macroglossia also elevated the tongue dorsum.
(c) To allow positioning of the tongue tip for the /r/ sound, patients lowered the mandibular position.
(d) The patients for the /p/ sound moved their lower lips in the vertical direction more than the normal.View full abstractDownload PDF (4023K) -
III. A Study of Recurrent Ameloblastoma After MandibulectomyKenichi KOZAKI, Minoru UEDA, Taketsugu NOMURA, Masao ITO, Iwai TOHNAI, ...1990 Volume 39 Issue 3 Pages 632-640
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSAmeloblastoma is pathologically described as a benign neoplasm. However, there are highly recurrent cases treated by conservative procedure. A few recurrent cases of ameloblastoma have been reported even after radical surgery.
We have treated four recurrent ameloblastoma cases after mandibular resection. Three cases were treated by peripheral osteotomy and one by segmental resection.
In this report four recurrent cases of ameloblastoma were analyzed in the points of surgical procedure and prognosis. The reuults were as follows:
1. The recurrence of ameloblastoma in all cases involved areas of the resected margin. Therefore, to prevent recurrence, wide resection of ameloblastoma to include surrounding normal bone, shoud be performed.
2. Reoperations in three recurrent cases were carried out with wide resection of mandible. In those cases, safety margins for resection of the tumor were established at 10 mm from tumor margin in medullary bone and at 5 mm in compact bone.
After long term follow up, there have been no recurrence clinically.View full abstractDownload PDF (10157K) -
Kazunori YONEDA, Noriko OKAZAKI, Tokio OSAKI1990 Volume 39 Issue 3 Pages 641-647
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSPlasmacytosis, a benign inflammatory disease rarely found in the oral cavity, is microscopically characterized with intensive subepithelial plasmacyte infiltrate and capillary formation and edema and necrosis of the epithelium. We experienced a case of plasmacytosis that occurred in the upper gum and cheek mucosa of a 75 year old woman. The gingiva central region was swollen, edematous, and ulcerated. The right side buccal mucosa was slightly reddish with crossed white lines forming a lace pattern. By clinical appearances, the gum lesion was suspected of denture fibromatosis with decbital ulcer, and the buccal condition was thought as lichen planus. Biopsied materials were taken from both lesions. Microscopically, sections from both lesions exhibited severe subepithelial infiltrate of polyclonal (positive for bothλandkchain) plasmacytes and showed characteristics of plasmacytosis circumorificialis. Laboratory examination of blood revealed no abnormality except for slightly elevated serum IgG level. The flappy, swollen gingiva was resected and a steroid ointment was topically applied to the gingiva and buccal mucosa. About 4 weeks after the treatment, the lesions completely disappeared and each region was covered with normal mucosa. From the above clinical and histopathologic findings, chronic mechanical irritation by the wearing denture was considered as the most causative factor for the disease.View full abstractDownload PDF (8472K) -
Takashi OKUDA, Makoto TOIDA, Hideki ICHIHARA, Tsutomu OHNOMA, Kinya KU ...1990 Volume 39 Issue 3 Pages 648-654
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe authors experienced and evaluated nine cases of non-Hodgkin's malignant lymphoma from 1981 to 1987. The results are as follows;
1) The percentage occupied in the oral cancers was 8.6%.
2) Seven patients were males and two were females. The age distribution showed biphasic pattern, two patients were under twenty and seven were above forty.
3) In all cases, the chief complaints were swelling or tumor formation at the involved lesion.
4) In six cases the lesion involved neck and/or submandibular lymphnodes and alveolar bone in four cases.
5) There was no specific symptom of malignant lymphoma.
6) In four cases the lesion was misdiagnosed as inflammatory diseases.
7) Histopathological classification was applied according to the LSG classification. Only one case was follicular lymphoma and the others were diffuse. In the cases of diffuse lymphoma, five cases were large cell type and three were medium cell sized type.
8) According to the Ann Arbor clinical staging, six cases were progressing stages.
9) Both radiation and chemotherapy were performed in six cases. Now the authors consider that even in stage I cases adjuvant chemotherapy after radiation is necessary for preventing relapses.
10) In the treatment procedure the most frequent complications were infectious diseases such as bronchitis and candidiasis.View full abstractDownload PDF (5667K) -
Report of One CaseYoshiyasu YOSHIKAWA, Yuji ASHIZAWA, Harunori NAGAI, Kohei MAEDA, Kohei ...1990 Volume 39 Issue 3 Pages 655-664
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of maxillofacial asymmetry involving (a) asymmerty of the mandibular bone, (b) lateral inclination of the occlusal plane of the maxilla, and (c) functional displacement of the mandible. The authors performed a sagittal splitting ramus osteotomy, to correct (a) and (c) and also the extrusion of maxillary buccal segments to correct (b).
The fixation was six weeks after the surgery released, and the maxillary occlusal plane was leveled to extrude the right maxillary buccal segments.
The treatment achievements were satisfactory.
The case maintained a stable occlusion without relapse.View full abstractDownload PDF (9365K) -
Report of Two CasesHideaki SAKASHITA, Masaru MIYATA, Morimoto HAYASHI, Hiroshi KURUMAYA1990 Volume 39 Issue 3 Pages 665-672
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSChronic osteomyelitis with focal proliferative periostitis resulting from mild irritation or infection is generally called Garré's osteomyelitis. Two cases of this disease that occurred in the mandible of an 11-year-old girl and a 13-year-old boy were reported and discussed with review of the literature.
The chief complaint was painless swelling at the mandibular region. The lesions were removed surgically and the pathological findings revealed features of chronic osteomyelitis compatible with Garré's osteomyelitis.View full abstractDownload PDF (10336K) -
Eisuke FUJIMOTO, Sigeyuki TAKATSUKA, Masaharu NAKAJIMA, Sinya KOJIMA, ...1990 Volume 39 Issue 3 Pages 673-682
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSClinico-statistical observation during the 5 years (1983-1987) was carried out on the in-patients at the Department of Oral Surgery, Kanazawa University Hospital. The results were as follows:
1. The total number of in-patients were 995 and that of out-patients were 10431 during the 5 years. The number of in-patients increased year by year.
2. The in-patients consisted of 528 males and 467 females. As to the age of in-patients, the 4 th decades were most frequently seen, followed by 5 th decades and by 3 rd decades.
3. Fourty one percent of in-patients were residents of Kanazawa City where our hospital is located and 10% were from outside Isikawa prefecture.
4. Twenty six percent of in-patients were referred from medical doctors, 33% from dentists.
5. The distribution of disease cases is as follows: cysts 290 (29%), inflammatory disorders 285 (29%), tumors 209 (21%), traumas 126 (13%), malformations and deformities 16 (2%), and others 69 (7%).
6. The admission periods varied from a day to 259 days and 63% of in-patients were discharged within 19 days.View full abstractDownload PDF (1086K) -
Kazuma FUJIMURA, Ken-ichiro MURAKAMI, Natsuki SEGAMI, Tadaaki YOKOYAMA ...1990 Volume 39 Issue 3 Pages 683-690
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESS246 joints in 200 consecutive cases of temporomandibular (TM) arthrosis were retrospectively studied. At the first presentation, classification of TM arthrosis was clinically attempted by means of the criteria proposed by Japanese Society for Temporomandibular Joint (1987). According to the criteria, these TM arthrosis patients were classified into five groups; type I characterized by myogenic problems, type II composed of chronic intra-capsular traumatic arthrosis, type III classified as internal derangements and subdivided to click and closed lock, type IV was featured as degenerative joint disease, and finally type V was judged as having psychiatric aspects.
200 patients were composed of 59 males and 141 females, ranging in age from 10 to 80 years with an average of 32.5 years. By classification, type III (70%) was the most common, followed by type II (12.5 %), type I (11 %), type IV (5 %), and type V (1.5 %). Type III was featured by younger patients around 20 years old, on the other hand, type IV was characterized by older patients with mean age of 60 years. Other I, II, V groups did not have any prediction of age decade. High intensity of pain and Jaw Dysfunction Score was revealed in types, II and III with closed lock, and high point of Activity Limitation Score was found in type V and III with closed lock. More limited opening mouth degree was depicted in type III with closed lock and type IV patient group. Although muscle tenderness or pain was positive in all type I patients, only 20-50 % of patients in another groups had positively tendered muscle.View full abstractDownload PDF (875K) -
Part 4: Epithelial Nests in the Fibrous Connective TissueYohko FUKUTA, Morio TOTSUKA, Yasunori TAKEDA1990 Volume 39 Issue 3 Pages 691-697
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA pahtological analysis of epithelial nests in the fibrous connective tissue of the epulis was made. Epihtelial nests were found in 13 of 174 cases, of which 5 were males and 8 females. These cases were classified by following 2 pathological types of epulis; 4 cases of the fibrous epulis and 9 cases of epulis with hard tissue formation. The histopathological natures of epithelial nests were classified into the following 3 types; 6 cases with cuboidal epithelial cell nests, 4 cases with both cuboidal and suquamous epihtelial cell nests, 2 cases with suquamous epithelial cell nests, and 1 case with columnar epithelial cell nests. These epithelial nests were suspected of odontogenic epithelium because of their histological characteristics. The epulis with epithelial nests presented here should be phathologically classified as non-neoplastic lesions, since these cases are reactive lesions without any evidence of the peripheral odontogenic fibroma.View full abstractDownload PDF (6128K) -
Sonou KOBAYASHI, Susumu OHMURA, Chika MIYAZAKI, Ken ITO, Ryoichi KAWAB ...1990 Volume 39 Issue 3 Pages 698-703
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSDermoid cysts and epidermoid cysts are of general occurrence, but occurrence in the oral region is relatively rare, and occurrence on one side of the sublingual region is extremely rare.
We report here the case of a 19-year-old female with an apparent plunging ranula on the left side of the sublingual region as diagnosed by clinical and photographic examination, but which proved, on histological examination, to be a true epidermoid cyst. W e discuss how to distinguish between an epidermoid cyst and a plunging ranula, especially on the basis of photographic diagnosis.View full abstractDownload PDF (8121K) -
Mari AKATANI, Yoshikuni SANGU, Tomohiro ANDO, Hiroyuki KANEKO, Kenji I ...1990 Volume 39 Issue 3 Pages 704-710
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSFour cases of fibro-osseous lesions were reported. The first was a case of fibrous dysplasia of bone that appeared at the left maxillary molar region of a 12 -year-old boy. The second and third cases were ossifying fibroma appearing at the right mandibular premolar region of a 28-year-old woman, and the left mandibular molar region of a 44 -year-old woman, respectively. The fourth was cementifying fibroma arising from the left mandibular molar region of a 25-year-old man. Differential diagnosis of these were discussed.View full abstractDownload PDF (11851K) -
Shinichiro SUZUKI, Shigeya WATANABE, Hiroshi KANEKO, Yuichiro KUWANA, ...1990 Volume 39 Issue 3 Pages 711-714
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe prevalence of asymptomatic oral lesions examined using rotational panoramic radiography (Panex-E) was studied. The subjects were 127 women and 473 men, students at Kanagawa Dental College in Yokosuka, Japan, with ages averaging 23.0 for women and 24.5 for men. The results revealed that the oral status of these subjects was very poor. Radiographic abnormalities were found in approximately 65 % of them. In particular, the prevalence of periapical radiolucency and stump tooth was about 4 times as high as reported in the United States. However, the potential incidence of true occult lesions which could not be detected by oral examinations was considered very low.View full abstractDownload PDF (435K) -
Masao ITO, Hitoshi OHARA, Kiyonobu SASAJIMA, Ryou FURUNE, Je Ryong KAN ...1990 Volume 39 Issue 3 Pages 715-723
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSPostoperative complications associated with oral surgical procedures were studied in 79 elderly patients. Circulatory and respiratory complications were most often found, therefore the risk factors influencing these main complications in the aged were additionally analyzed.
Basic systemic disease and surgical stress were statistically significant as influential risk factors in elderly patients following oral surgical procedures.
The most frequent postsurgical complications in the aged were circulatory diseases and second most frequent were respiratory diseases. This order was the same as that of the basic systemic diseases in the aged, so this result suggested strong influence of basic systemic disease.
Surgical stress, especially that due to extensive resection of malignant oral tumors, 8 hours or more long operating time, and 800 ml or more massive blood loss were the significant influential risk factors.View full abstractDownload PDF (966K) -
Special Reference to Oral LesionsMasaru SASAKI, Tsutomu OHKUBO, Ken ONODERA, Kiyoshi OOYA1990 Volume 39 Issue 3 Pages 724-728
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSMercury compounds have been used in antiseptics, diuretics and dental amalgam. An autopsy of acute poisoning of inorganic mercury is described.
Case report: A 59 year old Japanese male had taken up to about 5g of mixture of mercury chloride and mercury dichloride. Historically he complained of severe headaches since he had cerebral hemorrhage. On arrival at the hospital he was conscious with stridor and hemorrhagic sputum. After admission he was treated with oral intubation, gastro-intestinal lavage, fluid therapy, artificial respiration and forced diuresis. He died of circulatory and renal failures from treatments performed for about 8 hours. Post-mortem examination showed 1) multiple mucosal inflammatory erosions and coagulation necrosis of tongue, palate and other digestive organs, 2) periductal chronic inflammatory cell infiltration of salivary glands, 3) renal failure with severe coagulation necrosis of proximal tubules and 4) respiratory failure with purulental sputa in bronchioli and pulmonary edema.View full abstractDownload PDF (8218K) -
Report of a CaseAtsushi ASHIMOTO, Kazuo RYOKE, Shinzou ISHIKURA, Masaru KISHINO, Takaa ...1990 Volume 39 Issue 3 Pages 729-736
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA 47-year-old man was referred to our hospital whose chief complaint was gingival swelling of maxilla. Clinical findings were swelling of both sides of maxilla and submandibular lymphadenopathy. Surface of these swellings showed ulceration with necrosis. Biopsy was done from maxilla. He was admitted for examination and therapy. On admission other symptoms were fever, general fatigue and abnormal findings in chest X-ray at left lower field. Peripheral blood examinations revealed anemia and WBC, ESR elevated. And we found other lesion on head CT. After admission gingival swelling grew very fast. First we started Radiation therapy to control oral lesion and administered OK-432 (i.m.). Pathological findings suggested Histiocytosis-X and we performed Vincristine and steroid administration (i. v.). Temporary resolution of symptom could be seen in oral and submandibular region, but lymphadenopathy infiltrated whole bodies: axilla, femoral and abdomen etc.. Also head CT showed growing the lesion. It resulted poor response of thrapies (60Co total 30 Gy, VCR total 6 mg, Predonisolone 60 mg/day). Anemia gradually increased in spite of many transfusions. Disturbunce of liver and renal function and DIC followed. He died of breathing failure on 56th admission.
Autopsy showed that tumor cells infiltrated whole organs ; bone marrow, heart, hepar, spleen, lung and skin. Immuno-histochemical and ultrastructual studies suggested that cell orgin was not from so called T-zone-histiocytes and was from. reticulum cell. Final diagnosis was Malignant Histiocytosis (MH). Oral manifestations of MH is uncommon. But because of progressive and fatal disease, diagnosis and therapy should be done rapidly.View full abstractDownload PDF (11576K) -
Hiroyuki KUROKAWA, Eiro KUBOTA, Masaaki KOGA, Hirotoshi NAKAGAWA, Masa ...1990 Volume 39 Issue 3 Pages 737-743
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSSerum level of immunosuppressive substance (IS) was studied by single radial immunodiffusion method in 40 patients with primary oral cancer and 79 non-cancer patients in order to evaluate its usefulness as a parameter for monitoring therapy as well as recurrence of the tumor.
Mean values of serum IS in cancer patients and non-cancer patients were 687±284 μ/ml and 464±153 μ/ml, respectively. The mean IS value of normal healthy controls was 431±105 μ/ml, and the cut-off value was decided as 641 μ/ml, mean+2 SD. Positive rates of IS in cancer patient groups were 55 % in stages I and II, 40 % in stage III, and 68 % in stage IV. The mean values of serum IS level in cancer patients were significantly higher than that of the controls (p <0.01) and the positive rate of serum IS was found to be elevated as disease stage advanced. Histological analysis of tumor cells in the patients bearing squamous cell carcinoma (SCC) showed that the serum IS level of patients who had poorly differentiated SCC was much higher (mean ±SD ; 93±181 μ/ml) than that of patients who had the well differentiated (mean ±SD ; 616±159 μ/ml). The patients who had recurrent or metastatic cancer or died with cancer exhibited marked elevation of serum IS levels, whereas patients who had remained free of cancer in the follow-up period showed significantly lower serum IS levels. The rise and fall of serum IS level was closely correlated to the disease progression and/or remission. These data strongly suggest that serum IS is a useful parameter for monitoring the disease stage as well as therapeutic effect in oral cancer patients.View full abstractDownload PDF (760K) -
Kazuo YASUKAWA1990 Volume 39 Issue 3 Pages 744-764
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSTotal alveoloplasty of the mandible with split-skin graft was performed on 12 mandibular edentulous patients for whom ordinary prosthetic method had difficulties in improving masticatory function because of remarkable atrophy of the alveolar ridge. From the morphological and functional analysis made pre-and postoperatively, the following conclusions were obtained ;
1. All kept fairly good absolute height of the mandible, except 2 cases, which averaged 23.2, 21.3 and 19.8 mm at the anterior, premolar and molar regions, respectively.
2. From the morphological analysis of alveolar ridge, at the molar region, flat type (right: 5 sides left: 6 sides) improved to hillock type (right: 3 sides, left: 4 sides) or slope type (right: 2 sides, left: 2 sides), and all of slope type (right: 1 side, left: 1 side) improved to hillock type, postoperatively. On the other hand, at the anterior region, all of flat type (5 cases) improved to hillock type, postoperatively.
3. The denture base surface area was enlarged postoperatively in all cases, and magnification rate after operation ranged from 126 to 305 %, averaging 180 %.
4. From the results of masticatory function test using raw rice, average masticatory efficiency of 20 and 30 chews improved from 9.59% to 49.79% after operation.
5. The biting force at the molar region showed an increase postoperatively in all but 1 case. The increment of the biting force averaged 5.54 and 6.67 kg on the right and left sides, respectively.
6. The absolute height of mandible proved to be significantly correlated with postoperative surface area of denture base, postoperative masticatory efficiency and its increment. Those correlation coefficients were 0.7322 (p<0.01), 0.6446 (p<0.05) and 0.637 (p<0.05), respectively.
From the above it was suggested that masticatory function and stability denture wearing were more improved postoperatively for greater absolute height of the mandible. But it was impossible for the cases who have an absolute height of the mandible under 16 mm to be expected remarkable functional improvement after total alveoloplasty of the mandible.View full abstractDownload PDF (12159K) -
Kiyonobu SASAZIMA, Masao ITO, Je-Ryong KANG, Hideharu SUZUKI, Toshio K ...1990 Volume 39 Issue 3 Pages 765-771
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA tooth was extracted from each of three patients with idiopathic cardiomyopathy (ICM). Two of them had congestive cardiomyopathy (CCM) and the other hypertrophic obstructive cardiomyopathy (HOCM). HOCM sometimes results in sudden death due to increased heart rate and myocardial contractility. Consequently dental treatment of HOCM patients is high risk. In the present case, however, tooth extraction was performed without incident since local anesthetic without epinephrine was used and there was no physicomental stress. In one of the two CCM patients, there was the complication of serious hypertension noted prior to treatment. Consequently extraction could not be performed and the patient was treated by internal medicine so that the hypertension was controlled after four months medical treament. Tooth extraction was then successfully carried out. One of the two CCM patients showed bigeminy following administration of local anesthetic, but the other had no problems and thus tooth extraction was carried out successfully.View full abstractDownload PDF (2190K) -
Dental Infection Preventive ProcedureKenji MITSUDO, Yusuke TAKEUCHI, Iwai TOHNAI, Hideki MIZUTANI, Toshio K ...1990 Volume 39 Issue 3 Pages 772-777
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSApert syndrome is a craniosynostotic syndrome. With manifestations of oxycephaly, syndactyly, frontal bossing, and midfacial retrusion plus some intraoral minor anomalies.
We experienced a case of Apert's syndrome with dental infection. The case was a 35 year old unmarried female with chief complaint of spontaneous pain in the molar region of left mandibule. Treatment was antibiotic anti-inflammatory therapy, ferrotherapy for iron deficiency anemia, and tooth brushing instruction for her mother. General and oral conditions of this case is good at present.
It is necessary that all family should care in order for the patient to continue oral hygiene.View full abstractDownload PDF (5501K) -
Jun-ichi ASAUMI, Katsumi NISHIJIMA, Shin TAKAGI, Yutaka NISHIJIMA, Tos ...1990 Volume 39 Issue 3 Pages 778-786
Published: July 10, 1990
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSMTX·5-FU sequential administration (MF therapy) is one of biochemical modulation chemotherapy.
The effects and complications associated with MF therapy are evaluated in 14 head and neck cancer patients treated as follows: methotrexate (75 mg/body) administered by intravenous infusion for 1 hr, followed by 5-FU (500 mg/body) intravenous infusion for 2 hr on Day 1, MTX (75 mg/body) intravenous infusion for 1 hr on Day 4, and parenteral dose of Leucovorin on Day 2 and Day 5.
Complete response (CR) was attained in 1 patient and partial response (PR) in 9 patients. Complications observed were: increased serum transaminase levels (4), leucopenia (3), nausea or vomiting (3), and anemia (1).
It is concluded that MF therapy was effective and safe as neo-adjuvant chemotherapy for head and neck cancer patients.View full abstractDownload PDF (6132K)
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