日本口腔科学会雑誌
Online ISSN : 2185-0461
Print ISSN : 0029-0297
ISSN-L : 0029-0297
40 巻, 2 号
選択された号の論文の19件中1~19を表示しています
  • 藤田 雄敏, 田中 宏憲, 水谷 誠, 鈴木 純二, 前田 初彦, 亀山 洋一郎, 深谷 昌彦
    1991 年 40 巻 2 号 p. 321-327
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The present study was carried out to examine hyaline cells or plasmacytoid cells found in the pleomorphic adenoma of the palate histologically, immunohistochemically, and ultrastructurally. Furthermore, this study presented a review of 13 cases of pleomorphic adenomas with hyaline cells (including our case) in the literature. The round, firm and well-circumscribed tumor, measuring 2×2×2cm, was located in the hard palate of a 28-year old male. Histologically, the tumor consisted mainly of polyhedral or round cells arranged in sheets with the mesenchyma of a fibrous tissue containing hyaline-like component. A relatively large number of hyaline cells with a prominent eccentric nucleus and an eosinophilic cytoplasm were observed among the polyhedral or round cells. The tumor had a small cystic lumen in one area and was almost entirely surrounded with a fibrous capsule. Immunohistochemically, the cytoplasm of the hyaline cell was positive for S-100 protein, vimentin, keratin and GFAP. Ultrastructurally, the cytoplasm was almost filled with intermediate filaments. Clinicopathologically, of 13 previously reported cases of pleomorphic adenomas, 6 were males and 7 females. The ages of the patients ranged from 14 to 46 years with an average of 32.2 years. Of 13 cases, 7 were located in the palatal gland, 5 in the parotid gland and 1 in the submandibular gland.
  • 石田 雅栄, 神部 芳則, 赤坂 庸子, 保木 志朗, 小椋 秀亮, 浜本 洋子, 香川 靖雄
    1991 年 40 巻 2 号 p. 328-334
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    γ-carboxyglutamic acid containing protein (osteocalcin, bone Gla protein: BGP) which is one of non-cllagenous proteins in bone and has high affinity Ca2+ binding sites, is considered to play an important role in the process of bone calcification. However, the details of its physiological function have been unclear, and there have been very few reports about human bone and none about human dentin. In oredr to characterize BGP in dentin and human bone, we extracted BGP from human dentin and alveolar bone, and purified it by high performance liquid chromatography (HPLC). Then we determined the amino acid sequence of its N-terminus. Although the elution time of human BGP was slightly longer than that of bovine BGP by HPLC, the amino acid sequence agreed with that of bovine BGP and human BGP. Our results showed that human dentin and alveolar bone also contain BGP. The BGP level in human dentin (primary tooth) was 24.9±20.6μg/g, in human dentin (third molar) was 10.9±5.89, μg/g, and in human alveolar bone was 944±352 μg/g as determined by enzyme immuno assay using anti-bovine BGP serum.
  • 茂木 健司
    1991 年 40 巻 2 号 p. 335-348
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    A clinical and histopathological report was made on 5 cases of cementifying fibroma. The results were as follows:
    1. Clinical features;
    1 case was male and 4 were female.
    The age of the patients ranged from 23 to 57 years with a mean of 43.6 years.
    As for chief complaints, 3 cases were swelling, 1 case swelling and pus discharge, and 1 case nothing.
    The affected parts were the maxilla (2 cases) and the mandible (3 cases). The premolar and molar regions were affected in all 5 cases.
    In radiographs, they appeared as well-defined lesions with both radiolucent and radioopaque features.
    5 were operated on and no sign of recurrence has been found so far.
    2. Histopathological findings;
    Small, rounded cementicles were observed in most of these cases.
    Collagen fibers were observed around the calcified substance and in all 5 cases the amount differed.
    Microscopic preparations of the whole tumor in case 3 were made and revealed that lesion was sharply demarcated from adjacent bone and many cyst-like structures without any epithelial lining were found in the tumor.
    3. Immunohistochemical findings;
    The antibody to vimentin disclosed brown coloration within the fibrous stroma in all 5 cases.
    The SE antibody to keratin disclosed a positive reaction within the fibrous stroma in 3 of the cases.
  • 第3報: 顔面計測値 (点計測, 線的計測) との関係
    伊介 昭弘, 杉崎 正志, 田辺 晴康, 加藤 征
    1991 年 40 巻 2 号 p. 349-360
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    To examine relationships between measurements of mandibular fossa and facial morphology, we investigated measurements of anthropological facial points and mandibular fossa of 48 Japanese dry skulls with a three-dimenional measuring apparatus.
    The results were as follows.
    1. As to point and linear measurements, the value of facial measurements were correlated with the frontal (from articular tubercle to medial glenoid tubercle) and medial (from medial glenoid tubercle to post glenoid tubercle) length of the fossa.
    However, there as little correlation between the lateral side (from articular tubercle to post glenoid tubercle) length of the fossa and the facial measurement value.
    2. The angle of the line from the deepest point of the fossa to the articular tubercle correlated with the point of ANS, A, B, Pogonion, the distance of both fossa, the total mandibular length, and the length of mandibular corpus.
    3. The angle of the line from the deepest point of the fossa to the midpoint of the eminence was negatively correlated with the point of Nasion, ANS, A, upper first molar tooth, the distance of both Gonion, the distance of both fossa, the length of masseter attached and upper facial height.
    4. These findings suggested that the angle of the line from the deepest point of the fossa to articular tubercle was related to facial growth, and the angle of that to the midpoint of the eminence was related to the mid-facial growth and bite force.
  • 内崎 祐一, 池村 邦男, 藤原 利彦
    1991 年 40 巻 2 号 p. 361-367
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    In order to know if treatment using extracorporal shock weve lithotripsy (ESWL) is possible in sialolithiasis, we made a destruction experiment of salivary gland stones.
    In Each of 25 sialoliths, the weight was estimated and analyzed into structural elements. The examination of 25 sialoliths showed they were mainly composed of calcium phosphate, similar to hydroxyapatite. A soft X-ray film was taken in 5 sialoliths which were close in size and weight before sialolith disintegration. All sialoliths had a calcified core and shell.
    Each sialolith was first treated by 20 times, 18 KV shock wave and three of the 5 calculi were disintegrated leaving the core. Further shock wave (20 KV, 20 times) was added to the other two calculi and one was destroyed. Another one may be destroyed by more exposures. The hydroxyapatite (30% porous rate) as contuol also was fragmented by 20 times, 20 KV shock wave.
    The results indicate shock wave can destroy the sialolith, but prior to the clinical application, the influence on the surrouding tissue by the shock wave and the discharge method of the fragments should be investigated.
  • 富樫 洋介, 大橋 靖, 吉田 重光
    1991 年 40 巻 2 号 p. 368-376
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    In order to obtain an experimental model of cleft palate in growing rats, the midpalatal suture of the maxillary palate in 20 day old wistar rats was drilled with a #3 (1.2 mm) round bur and the histological healing process was studied chronologically.
    The results are summarized as follows:
    1.15 days after drilling, the entire circumference of the hole was covered by oral epithelium. No inflammatory cells were observed in the lamina propria and new bone formation was progressing on the bony edge of the operated field. As a result, the margin of the wound was considered to be healed completely within 15 days after drilling.
    2. The body weight of the rats was slightly lower than that of a control group shortly after drilling. No difference was observed between the two groups, however, 20 days after the operation.
    3. It is concluded that an experimental model of the cleft palate rats approximating the anatomical condition can be obtained by drilling the midpalatal suture of young rats.
  • 第1報: 臼歯喪失が迷路学習に及ぼす影響
    梅田 健吾, 沢木 佳弘, 伊藤 正夫, 増田 晃司, 竹原 公善, 上田 実, 金田 敏郎
    1991 年 40 巻 2 号 p. 377-383
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    The purpose of this study was to examine the effects of teeth loss on learning and memory ability in the radial maze task in adult rats.
    Twenty male Wistar rats (10-weeks-old) were divided into 2 groups. The molar teeth of ten rats were extrarted unilateraly under general anesthesia, and the remaining ten rats were anesthetized as control.
    Learning and memory abilities of both groups were tested and compared in the 8-arms radial maze task.
    There was a tenedency that tooth-loss rats had impaired learning and memory in the radial maze task ; these were demonstrated by a decrease in correct responses and an increase in total errors. These results suggest that tooth loss may affect the learinng and memory ability in adults.
  • 富樫 洋介
    1991 年 40 巻 2 号 p. 384-397
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Little is known about the healing process after palatoplasty. The aim of the present study is to clarify the course of maxillary growth after palatoplasty through histological and quantitative examination using experimental cleft palate rats which were produced before. Palatoplasty was performed on 60 experimental cleft palate rats aged 35 days (group A) and the healing process was examined histologically. The subsequent increase of the palatal width of the maxilla in this group was measured and compared with that of 20 experimental cleft palate rats not receiving palatoplasty (group B) and 10 normal rats (group C).
    The results are summarized as follows:
    1. In group A, the operated field was in the process of wound healing by 20 days. The bony edges were surrounded by thick and dense collagen fibers forming scar tissue at 60 days after the operation, which was believed to restrain the lateral growth of the maxilla.
    2. 20 days after the operation, new bone formation was progressing on the bony edge of the midpalate, however, it was not observed 60 days after the operation.
    3. Quantitatively, the lateral growth of the maxilla in group A was significantly lower than in groups B and C, while the growth of the palate not subjected to the operation was normal.
    4. It is concluded that poor bilateral growth of the palate in cleft palate patients may be assumed to result from palatoplasty at an early age.
  • 細野 隆也, 高橋 喜久雄, 佐藤 研一, 藤村 真示
    1991 年 40 巻 2 号 p. 398-405
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Bone resorption-inducing activity was detected in the conditioned medium of rat osteosarcoma MSK cultured cells, being characteristic of osteoblast-like cells. The inducing activity was greater in stationary phase than in the exponential phase of cell growth and was enhanced two-fold with addition of hPTH in the medium. The optimum concentration and the period for hPTH treatment were 10-8M and 2 hr, respectively. Maximum activity was observed between 10 and 24 hr in incubation of the assay. A factor about 500 to 3, 000 Da in molecular weight, other than hPTH, would be feasible for the bone-resorption inducing activity in the conditioned medium of MSK cultured cells.
  • 特にbleomycinを中心に
    関口 隆, 宮川 明, 平塚 博義, 野口 誠, 三又 康永, 山本 悦秀, 小浜 源郁, 山岸 雅彦, 森 雅樹
    1991 年 40 巻 2 号 p. 406-414
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Using computed tomography of the chest (chest CT) and pulmonary function test, lung injury caused by anti-cancer agents was studied in 27 patients with oral cavity malignant tumors.
    Seven of the 27 patients were preoperatively administered bleomycin (BLM) alone at 42.5-90mg, 10 were given BLM 15-135mg and methotrexate (MTX) 1000mg, and cisplatin (CDDP) at either 80 or 160mg, and then the tumor was removed surgically.
    Upon chest CT examination, one of the 7 patients treated with BLM alone and eight of the 20 patients treated with combination chemotherapy had lung injury which appeared as a curvilinear shadow of an interstitial pneumonia pattern in the bilateral dorsosubpleural area. In pulmonary function tests, abnormal values were not seen in those patients treated with BLM alone, while there was a decrease of DLco and DLco/VA in patients treated with combination chemotherapy. From these results, it is recommended that patients with malignant tumors of the oral cavity who are treated with combination chemotherapy be even more carefully evaluated for lung injury.
  • 平山 丈二, 早津 良和, 辻 龍雄, 福田 てる代, 伊田 正道, 田辺 均, 松富 貞男, 安山 泰吾, 中島 嘉助, 篠崎 文彦
    1991 年 40 巻 2 号 p. 415-422
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Clinico-statistical observations on 92 patients with malignant tumors in oral and maxillofacial regions treated at the Department of Oral and Maxillofacial Surgery, Yamaguchi University Hospital from January 1984 to December 1988 were presented.
    Of 92 patients, 52 were male and 40 were female (1.3: 1). The mean age was 61.8 years, 80.4 % of patients were over fifty. Of all cases, 62 (67.4%) were referred to private dental clinics and oral surgery clinics of city hospitals. The primary tumors sited on the tongue in 21 cases, mandibular gingiva 20 cases, mouth floor 14 cases, maxillary sinus 12 cases and so on. 79 cases (85.9%) were pathologically diagnosed as squamous cell carcinoma. The others were 4 cases of mucoepidermoid tumor, 3 cases of adenoid cystic carcinoma, 3 cases of malignant lymphoma and so on.
    According to the TNM classification by UICC (1978), 68 cases of primary squamous cell carcinoma were classified as 7 cases (10.3%) of T1, 30 cases (44.1%) of T2, 9 cases (13.2%) of T 3, 22 cases (32.4%) of T4, and further classified as 7 cases (10.3%) of stage I, 17 cases (25.0%) of stage II, 15 cases (22.1%) of stage III and 29 cases (42.6%) of stage IV. In the N classification, cervical lymph nodal metastasis was found in 40 cases (58.8%).
    The 5 year survival rate of 68 cases treated in our clinic was as follows: stage I: 71.4%, stage II: 63.0%, stage III: 52.4%, stage IV: 14.0% and total 68 cases: 39.1 %. The 5-year survival rate classified by location was as follows: buccal mucosa: 71.4%, tongue: 62.7%, mouth floor: 44.5%, gingiva: 38.0%.
  • 加藤 隆三, 川尻 秀一, 西出 雅博, 室木 俊美, 熊谷 茂宏, 中川 清昌, 山本 悦秀
    1991 年 40 巻 2 号 p. 423-431
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Epulis is a clinical term describing a localized swelling of the connective tissue of gingiva, a common gingival disease. Clinico-pathological analysis was made of 59 equlis cases examined in the Department of Oral Surgery, Kanazawa University Hospital, during the period from 1980 to 1989. The results were follows:
    1. They were classified histo-pathologically into 5 patterns, 31 cases of epulis granulomatosa (52.5%), 18 cases of epulis fiburosa (30.5 %), 5 cases of epulis fibromatosa (8.5 %), 3 cases of epulis osteoplastica (5.1%), 2 cases of epulis hemangiomatosa (3.4%), according to Ishikawa classification (1982). No case of giant cell epulis was found in the present series.
    2. Epulis was more evident in patients 30 to 50 years of age, and much more common in females than in males by a ratio of 1.7: 1.
    3. Epulis in the majority of 59 cases was located in the anterior segments of the jaws.
    4. Epulis in the majority of 59 cases was soybean-sized.
    5. Treatment was by surgical excision. In 26 cases, extraction and incision were performed. In 33 cases, incision was performed. 2 cases had recurrence and were reoperated. The prognosis is good and no evidence of recurrence has been observed to date.
  • 米田 和典, 尾崎 登喜雄, 松木 宏真, 山本 哲也, 植田 栄作
    1991 年 40 巻 2 号 p. 432-444
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Side effects and complications in cancer treatments were comparatively studied on 35 highly aged oral cancer patients (≥70 years, HA group) and 38 younger patients (40-60 years, MA group). The results are as follows.
    1) Serum albumin level in the HA group was originally lower than that in the MA group, and lowering of HA group's albumin level was allowed to persist for a longer time after induction therapy.
    2) Red and white blood cells decreased with cancer treatments in the groups. Both blood cells of MA group patients nearly increased to the original counts within a short time after therapies, but suppressed bone marrow condition continued even after remission in the HA group.
    3) BUN level in the HA group elevated markedly with therapies, and the elevation was statistically significant high magnitude when compared with that in the MA group.
    4) Distressed lung functions associated with therapies were found in both groups. In the tests examined, % DLco was most cleary decreased and seemed to be most useful for respiratory function monitoring.
    5) No difference in original composition of lymphocyte subsets could be found between two groups. CD4 cell decrease and contrary CD8 cell increase were observed during cancer treatments, but NK subsets were hardly affected. Lymphocyte blastogenesis and allo-antigeninduced CTL activity were in low levels while NK and LAK activity returned to their original levels within the discharge time.
    6) MA group patients originally had greater complications mainly in the circulatory system, but multiple complications resulted from cancer therapy of HA group patients. As complications induced by treatments, liver dysfunction was most frequent, and mental disturbance did not negligible.
    The above results supported that inductive chemo-radiotherapy-induced side effects such as myelosuppression, malnutrition, renal and liver dysfunction and immunosuppression, and systemic complications distress highly aged patients more severely, therefore, more cautious cancer therapy avoiding irreversal side effects should be more demanded for older patients.
  • 第1報 歯科疾患およびその治療状況
    吉田 雅司, 向井 洋, 山下 佐英, 石神 哲郎, 谷口 良昭
    1991 年 40 巻 2 号 p. 445-453
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Dental diseases of psychiatric hospital inpatients have not been studied sufficiently. They rarely received dental examination and treatment.
    Recently we surveyed the dental diseases of 310 patients of Taniguchi Hospital, which was established in 1961, and 327 inpatients treated at the Department of Psychiatry. The results obtained were as follows;
    1) Schizophrenia was the main mental disorder of the surveyed inpatients (53.5%).
    2) 203 inpatients were dentulous. Their caries positive rate was about 90%, and only 5 women were without caries teeth. The number of present teeth was 3669 which consisted of intact teeth (42.4%), treated teeth (25.3%), and untreated teeth (32.3%).
    3) Rate of the missing teeth was 94.2% and missing teeth totalled 5011, 56.0% of which had prosthetic appliance.
    4) Average number of present teeth, missing teeth and DMFT per person was 11.9, 16.1 and 22.3 respectively.
    5) The survival rate of the lower canine was highest (57.7%) and the lower molar was lowest (23.9%).
    Dental disease rate was higher in mentally handicapped adults, and their condition of treatment was worse than that of ordinary Japanese adults, which was compared to the dental disease survey report in 1981 by the Medical Affairs Bureau, Ministry of Health and Welfare, Japan.
  • 岩井 正行, 池田 寿人, 小竹 彌, 梶村 悦朗, 古田 勲, 岡田 英吉
    1991 年 40 巻 2 号 p. 454-459
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    A case of angiomyolipoma in the upper lip of a 66-year-old female was presented. Histologicl examination of this tumor revealed an intimate admixture of three mesenchymal components smooth muscle, blood vessel and mature fat cells. Only two cases of angiomyolipoma originating from the oral region had been repored in the lierature. Distinctions between angiomyolipoma and angiomyoma, mesenchymoma is discussed.
  • 坂下 英明, 宮田 勝, 宮本 日出, 車谷 宏, 林 守源
    1991 年 40 巻 2 号 p. 460-468
    発行日: 1991/04/10
    公開日: 2011/11/25
    ジャーナル フリー
    Benign lymphoepithelial lesion is a salivary gland enlargement characterized histologically by atrophy of glandular parenchyma and lymphocytic infiltration, with island of epithelial and myoepithelial cells replacing the intralobular ducts. Macrosropically, cyst formation occasionally occured, but the cysts remained small.
    A case of this disease resembling lymphoepithelial cyst in parotid gland was reported. A 60-year-old Japanese female complained of a painless mass in her right parotid region. After investigations, the mass was diagnosed as a benign parotid gland tumor with cyst formation.
    Under general anesthesia, the tumor was resected by superficial parotidectomy, and the exposed facial nerve was covered with a sternomastoid muscular flap to prevent Frey syndrome, which of the occurs after this kind of operation.
    On pathological examination, the lesion was found to be this disease. Cystic area lined by stratified squamous epithelium with abundant lymphoid tissue beneath the epithelium, resembled lymphoepithelial cyst in parotid gland. In the solid area, we found diffuse lymphoid infiltration and epimyoepithelial island formation. The cyst we diagnosed may have arose from the benign lymphoepithelial lesion.
  • 高森 康次, 海老原 務, 永井 哲夫, 田中 陽一
    1991 年 40 巻 2 号 p. 469-478
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Pigmented nevus is a proliferative hamartoma-like mole consisting of melanogenic cells. Compared with the incidence of pigmented nevus on the skin, its occurrence on the oral mucosa is rather rare. We experienced two pigmented nevus cases: a compound pigmented nevus on the gingiva of mandible (21-year-old female) and a junctional pigmented nevus on the palate (six-year-old female). We conducted immunohistochemical investigations in these cases and reported their results. Comparatively reviewing the reported cases in both Japanese and overseas literature, we obtained the following results.
    (a) Histologically, the intradermal type is the most common, compound and junctional types follow sequentially.
    (b) Intradermal and compound types usually develop on the gingiva of mandible, lip, and buccal mucosa. The junctional type often develops on the palate.
    (c) More women than men have pigmented nevi.
    (d) Pigmentation occurs in most cases.
    (e) Almost all intradermal and compound pigmented nevi are protuberant, whereas pigmented nevus of the junctional type is usually smooth.
  • 森家 祥行, 村上 賢一郎, 津田 圭紹, 藤村 和磨, 宮木 克明, 瀬上 夏樹, 小西 淳二, 飯塚 忠彦
    1991 年 40 巻 2 号 p. 479-488
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    It has already been recognized that MRI is very useful for description of clinical pathology in the temporomandibular joints (TMJ). But detailed reports on MRI findings after treatments for TMJ internal derangements were rare. We evaluated MRI findings in 45 closed lock cases (50 joints) after conservative/surgical treatments.
    For imaging of the temporomandibular joint disorders, 1.5 Tesla superconducting magnet system (GE, Signa) and Toshiba MRT-22 were applied. MR imaging for the cases with internal derangements without reduction before treatment was performed after treatments.
    Our study (45 cases, 50 joints) consisted of conservative treatments (22 cases, 23 joints) and surgical treatments (23 cases, 27 joints). Surgical treatments were all made arthroscopically. Those unlocked by conservative treatments (19 cases, 20 joints) consist of splint effective (10 cases, 10 joints), medication effective (2 cases, 2 joints), and manipulation effective (7 cases, 8 joints). In splint treatments, locking or unlocking the disk was clinically diagnosed two months after splint setting, and MR imaging was performed.
    Concerning MRI findings after treatment, disk reduction was not attained in ineffective cases of conservative treatment, and it also was not obtained, even if improvement in disk and condyle movability was observed, in most of the effective cases treated by conservative treatment or arthroscopic surgery. Pre/postoperative disk configuration was also evaluated.
  • 前田 寛治, 田辺 均, 鈴木 通彦, 辻 龍雄, 早津 良和, 中島 嘉助, 篠崎 文彦
    1991 年 40 巻 2 号 p. 489-498
    発行日: 1991/04/10
    公開日: 2011/09/07
    ジャーナル フリー
    Adenolymphoma, so called Warthin's tumor, is a relatively rare epithelial benign tumor of the salivary gland.
    In this paper, we described a rare case of Warthin's tumor in bilateral parotid glands in a 69-year-old woman.
    The mass on the right side was 50 mm in diameter and the one on the left side was 20 mm in diameter. Both masses were well-diefined, movable, elastic hard and painless tumors.
    CT, scintigram and echogram were done.
    Clinical diagnosis was benign tumor in bilateral parotid regions, suspision of Warthin's tumor.
    The tumors were surgically removed. The sizes of the right tumor was 48×34×25 mm and the left tumor was 27×20×14 mm respectively.
    Histopathologic diagnosis was Warthin's tumor (Adenolymphoma). The tumor consisted of epithelial and lymphoid tissues. The epithelial tissue had bilayer construction, the inner layer composed of tall columnar cells with acidphilic cytoplasma, and outer layer composed of cuboidal cells. The lymphoid tissue had germinal centers.
    Immunohistochemical study was done by using two monoclonal antibodies; KM-93 and KM-231. Histogenesis of epithelium of Warthin's tumor was discussed.
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