巻号一覧
41 巻 (1992)
- 4 号 p. 631-
- 3 号 p. 415-
- 2 号 p. 213-
- 1 号 p. 1-
41 巻, 4 号
選択された号の論文の15件中1～15を表示しています
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飯田 明彦, 島田 久八郎, 北村 昌夫1992 年 41 巻 4 号 p. 631-646
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーThe reflex control mechanism of the extrinsic tongue muscles initiated from the hard palate was investigated in decerebrated cats. Electromyograms of the genioglossal muscles (tongue protrusive muscles) and the styloglossal muscles (tongue retractive muscles) were recorded with bilateral stimuli to the hard palate at the level of incisal papilla, intermolar region or posterior part of the hard palate. The findings obtained were as follows:
1. The reflex threshold was below 10g. When 50g of stimulation was applied, the reflex response was complete.
2. Inhibitory responses in the genioglossal muscle and excitatory responses in the styloglossal muscle could be easily elicited contralaterally by unilateral stimuli of hard palate at the level of incisal papilla.
Excitatory responses in the genioglossal muscle and inhibitory responses in the styloglossal muscle could be easily elicited in the bilateral muscles by unilateral stimuli in the intermolar region. These responses were more predominant in the ipsilateral muscles.
These results showed that extrinsic tongue muscles related to back and forth tongue movement were controlled reciprocally by stimuli to the hard palate.
3. Only inhibitory responses were elicited both in the genioglossal and styloglossal muscles by stimuli to the posterior part of the hard palate.
4. Excitatory responses were amplified when muscle activity before stimuli (background activity: BGA) was low and inhibitory responses emphasized in high BGA.
It was suggested that the tongue movements during mastication and deglutition were controlled by these integrative reflex controls of the extrinsic tongue muscles. The mode of action of the palatal plate which improved the tongue function was also discussed.抄録全体を表示PDF形式でダウンロード (2301K) -
長門 俊一, 升野 博志, 松本 光治郎, 谷岡 博昭1992 年 41 巻 4 号 p. 647-654
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーTo elucidate the mechanisms of lipid droplet accumulation in the secretory cell cytoplasm of the salivary gland of newborn rats, triacylglycerol and cholesterol content and lipoprotein lipase activity in the submandibular-sublingual glands was measured. Triacylglycerol reached the maximum level on Day 1 after birth and then gradually decreased till Day 4. After Day 4, triacylglycerol did not change and was maintained at this level. On the other hand, cholesterol did not change during postnatal development. Lipase activity attained its maximum level in these glands obtained from rats immediately after birth and then decreased rapidly. Lipase activity in the glands of fasted 1 -day old rats was much higher than that in the gland of fed 1 -day old rats. Immunoinhibition study using antiserum against lipoprotein lipase showed that the antiserum inhibited lipoprotein lipase activity from the submandibular-sublingual gland, and lipase activity decreased to 30-40 % of the total lipase activity. On the other hand, nonimmune serum had little effect. These findings suggest the following.
1) The principal component of accumulated lipid droplets in the secretory cell cytoplasm of the salivary gland is triacylglycerol.
2) Sixty to seventy percent of the total lipase activity originate in lipoprotein lipase.
3) Lipoprotein lipase in the newborn rat salivary gland is a heart type.
4) An increase of lipoprotein lipase activity is recognized prior to accumulation of triacylglycerol.抄録全体を表示PDF形式でダウンロード (900K) -
秋月 一城, 翠川 鎮生, 高橋 喜久雄, 佐藤 研一, 藤村 真示1992 年 41 巻 4 号 p. 655-667
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーWe examined the osteoblastic and oncological properties of the established rat osteosarcoma cell line MSK with respect to 1) cyclic AMP (cAMP) production and alkaline phosphatase (ALPase) activity, and 2) the interaction of protein tyrosine kinase activity with parathyroid hormone (PTH)-response. The ALPase activity increased with time in culture medium and was reduced by PTH in a dose dependent manner. The content of cAMP in the cells was dose-dependently increased with the addition of PTH and conspicously enhanced to a maximum of 180 times at 5 min with 0.2 mM 3-isobutyl-1-methyl-xanthine. This response was suppressed by 6-hour pretreatment of the cells with 1, 25 dehydroxyvitamin D3. Responses to other bone metabolic hormones such as calcitonin and prostaglandin E2 were negligible compared to the controls.
MSK cells possessed significantly high protein tyrosine kinase (PTK) activity, which was inhibited dose-dependently by ST638 (ST), a PTK specific inhibitor, both in cells in vitro and in the membrane fraction component of the cells. PTH itself did not elevate the PTK activity.抄録全体を表示PDF形式でダウンロード (1767K) -
森 啓充1992 年 41 巻 4 号 p. 668-687
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーThe present study explores biological mechanisms for electric call us formation in terms of immunohistochemical assessment for glycosaminoglycans (chondroitin 4 sulfate, chondroitin 6 sulfate, dermatan sulfate, and keratan sulfate), and S-100 protein α and β during the process of electric callus formation.
On day one after electrical stimulation, the periosteum became considerably thickened and showed two layers. On day two, a sall amount of osteoid tissue was yielded between the electrically stimulated periosteum and the cortex. On day three, the newly formed osteoid tissue progressed to a considerable thickness.
On day five, the osteoid tissue continued to mature. On day seven, the osteid tissue began to calcify and finally formed bone tissue. During this stage, condroidal tissue appeared between the newly formed bone tissue and periosteum. On day nine, calcification of both osteoid and condroidal tissue progressed.
On days 11, 14, and21, this formed bone tissue showed considerable growth as a matured type, and changed to bone trabeculae. Both osteoblasts and osteoclasts existed around the bone tr abeculae.
In the initial stage, periosteum showed moderate staining for glycosaminoglycans, while osteoid tissue showed a strong one. In the stage of matrix calcification, periosteum was stained weakly for proteoglycans, and calcified osteoid tissue showed slight or negative staining for proteoglycans. Cartilage matrix was positive for proteoglycans. The condrochte was strongly stained for keratan sulfate, derumatan sulfate, and condroitin sulfate, and the nucleus was positive for S-100 protein and S-100α.
It is suggested that proliferated mesenchymal cells synthesized proteoglycans that were accum ulated in precalcified osteoid tissue as matrix components. When calcified, the matrix reduced staining intensity for proteoglycans. S-100 protein expression in chondroid tissue suggested that the protein was related to mechanisms of calcium signaling in mineralizing tissue and to calcium regulation for ossification.抄録全体を表示PDF形式でダウンロード (35305K) -
2. 腎・泌尿器系および血液・造血器系疾患についての臨床的検討栗田 浩, 岩原 謙三, 倉科 憲治, 腰原 高志, 荻場 明子, 小川 浩樹, 小木曽 暁, 田村 稔, 峯村 俊一, 田中 廣一, 小谷 ...1992 年 41 巻 4 号 p. 688-694
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーClinico-statistical analysis of patients with renal and urogenital disease and hematological disease who needed dental and oral surgical management was reported.
1) Among the 7988 outpatients who visited our hospital in the period of from July 1986 to June 1990, there were 100 patients with renal and urogenital disease, an incidence of 1.3%. Fifty seven patients had some other diseases, and this incidence was higher than that of all medically compromised patients. About 40% of the patients had a surgery. No complication associated with the treatment occurred.
2) There were 196 patients with hematological disease, an incidence of 2.5%. This group tended to consist of many young patients and those who were refferred to our department from other departments in our hospital. More than half of the patients suffered from malignant neoplasms. So there were many pediatric patients, caries treatment and extraction of diciduous predecessors were done more often. Four patients visited our department complaining of oral bleeding. Surgical treatment was done in 74 patients, and the treatment was not easy in 34 patients. Complications associated with tooth extraction occured in 5 patients. Two patients infected with HIV and one with HBV were observed.抄録全体を表示PDF形式でダウンロード (884K) -
長田 哲次, 大石 正道, 白土 雄司, 樋口 勝槻1992 年 41 巻 4 号 p. 695-707
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーClinical use of ceramic hydroxylapatite (HA) as a graft material in the oral and maxillofacial minor surgery was investigated. In this study, 31 patients (7 cases of cysts in the maxilla and mandible, 2 cases of chronic osteomyelitis, 10 cases of cleft lip and palate, 11 cases of chronic marginal periodontitis, and 2 cases of luxation of tooth) were treated with this material and followed up for 0.5 to 4.0 years. The results were as follows;
1. Post-operative discharge of HA granules were seen 11 of 31 cases. There were two types of discharge; one was the discharge from the operated wound within two weeks and the other was so-called “trans-epithelial elimination” in which HA fragments were released from non-inflammatory gingiva more than one month after operation.
2. Application of HA to the bone defect of a cyst of the maxilla or the mandible with stable teeth was of little use. However, in the case of radicular cyst, HA was efftctive for stabilization of apicectomized teeth.
3. Reconstruction of alveolar bone defects with HA showed good prognosis.抄録全体を表示PDF形式でダウンロード (22401K) -
特にアンケート調査による処置法の検討田中 信幸, 田代 貴之, 冨塚 謙一, 内出 尚里, 君島 裕, 吉増 秀實, 天笠 光雄, 塩谷 健一1992 年 41 巻 4 号 p. 708-713
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーWe performed clinico-statistic investigation of 695 maxillofacial fracture cases in our department, The First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tokyo Medical and Dental University, for a period of 13 years between 1977 and 1989. There were about three times as many male as female patients and the majority of the patients were between the ages of 10 and 30 years old. Almost half of all the cases had mandible fractures. And there were few severe cases such as the case of Le Fort II or III fracture and combined fracture of maxilla, mandible, and zygomatic bone. Many patients visited our hospital within 1 week after injury and the most common causes of fracture were traffic accident, fall, and sports.
Our hospital is not designated as an emergency hospital and so we do not have many open-reduction cases, but the results of our cases were satisfactory. The questionnaire survey results indicate that we should invent how to reduce the period of intermaxillary fixation.抄録全体を表示PDF形式でダウンロード (682K) -
田中 啓太, 池村 邦男, 大矢 亮一, 大田 俊行1992 年 41 巻 4 号 p. 714-720
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーIn patients with probable primary amyloidosis, multiple myeloma and rheumatoid arthritis, we studied whether lip biopsy was useful for definite diagnosis of amyloidosis, and whether there was a difference in the location and the degree of amyloid deposition between the minor salivary gland of the lip and the labial mucosa.
Amyloid deposition was seen in 20 (33, 3 %) of the examined 60 patients. In six of these 20 patients who were diagnosed as positive by lip biopsy, biopsy specimens were taken from other organs and they also showed amyloid deposition. In six of 40 cases having showed negative results by the lip biopsy, the biopsy of other organs was performed. Only one case that received stomach biopsy showed positive deposition.
In 25 cases, the biopsy specimens were simultaneously taken from the labial mucosa and the labial glands, and both tissues showed the same result about amyloid deposition. But, amyloid deposition in the labial gland was more apparent than that in the labial mucosa. In the labial gland, amloid depositi on was obvious in the periductal, periacinar and perivascular tissues, while in the labial mucosa it was recognized in the stroma and perivascular tissues.
The degree of amyloid deposition was compared among primary amyloidosis, multiple myeloma and rheumatoid arthritis, and in the patient with rheumatoid arthritis amyloid deposition was more apparent.
Lip biopsy provides reliable information on amyloid deposition. A biopsy procedure is simple and has no complications.
We think lip biopsy is the best examination choice for definite diagnosis of amyloidosis, and the minor salivary gland is more suitable for diagnosis.抄録全体を表示PDF形式でダウンロード (9227K) -
吉田 雅司, 杉原 一正, 水枝谷 渉, 山下 佐英1992 年 41 巻 4 号 p. 721-725
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーThe recovering process of the anemia following 400ml blood donation in healthy female volunteers was studied hematologically. The advanced erythropoietic ability was observed from the first day following the phlebotomy. On the 14th day, the rates of reticulocyte and the mean corpuscular hemoglobin concentration normalized and the serum erythropoietin level indicated a maximum in spite of the decreases of serum iron and ferritin.
There were no obvious side effects following a 400ml phlebotomy for healthy females. It was suggested that the 2 weeks after the 400m1 autologous blood donation would be a suitable period for orthognathic surgery.抄録全体を表示PDF形式でダウンロード (433K) -
舌骨との関係について山森 ゆか, 奥田 孝, 安岡 忠, 市原 秀記, 阿部 一雄, 立松 憲親, 岡 伸光1992 年 41 巻 4 号 p. 726-730
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーThyroglossal duct cyst is a rare lesion, and originates from the remaining epithelium of the thyroglossal duct. W e report a case of the thyroglossal duct cyst and discuss its relation to the hyoid bone.
A 13-year-old boy was referred to us because of a tumor at the submental region on April 19, 1989. An elastic hard mass with a slight mobility, about 40×40×30mm, was palpated at the region. Computed tomography revealed a cystic lesion adhering to the hyoid bone. A diagnosis of thyroglossal duct cyst was made, and extirpated with a fistula to the cecal foramen under general anesthesia on July 27, 1989. The hyoid was partially removed with the cyst because of a persistent adhesion. The cyst, 35×40×25mm, showed a multilocular appearance, and the content had a jelly-like viscosity with a foul odor. Histopathology revealed that the cyst was lined with stratified squamous epithelium, which was partially replaced by granulation tissue. Many small cystic lumens lined by ciliated columunar epithelium were noted on the periphery to the fistula. Many mucous glands were also seen adjacent to the microcysts.
High incidence of the cyst is noted in the subhyoid contrary to the low incidence in the suprahyoid region. Accessory thyroid glands often associate with the subhyoid type despite almost concomitant mucous glands in the suprahyoid type. We accordingly speculated a close relationship between the cyst and hyoid, because the invaginating route of the thyroglossal duct is thought to be distorted by the appearance of the anlage and subsequent rotation of the hyoid.抄録全体を表示PDF形式でダウンロード (8433K) -
丸茂 町子, 菅原 由美子, 大澤 篤子, 古内 寿, 阪本 真弥, 高橋 和裕, 三條 大助1992 年 41 巻 4 号 p. 731-738
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーA case of progressive facial hemiatrophy of the left side in a 60-year-old woman was reported, especially with regards to oral symptom and X-ray CT images.
1) The etiology of this atrophy is at present unknown but in this case the patient first noticed the erosion and pigmentation of the lip chin and palpebra of the left side after being hospitalized for tonsillectomy at 19 years of age.
2) Atrophy was noted on the left side of the face, neck, hand, and truncus including skin, subcutaneous tissues, salivary gland, muscles, and bones.
3) The teeth were normal.
The tongue was affected, and the atrophic half was reduced in size.
The gingiva (Γ2 3 4) was involuted.
The soft tissues of the soft palate and pharynx of the left side were lacking in depth and width.
4) The salivary flow rate and sour and bitter taste sensitivity on the tongue of the left side were decreased.抄録全体を表示PDF形式でダウンロード (12170K) -
第2報: 通常歯牙欠損症例における咀嚼能率の変化について田中 益子, 上田 実, 村上 斎, 久野 雅芳, 篠田 鉄郎, 各務 秀明, 川合 道夫, 新美 敦, 江幡 晃治, 金田 敏郎1992 年 41 巻 4 号 p. 739-742
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーMasticatory efficiency of twelve fully or partially edentulous patients who underwent occlusal reconstruction utilizing osseointegrated implants at the Department of Oral Surgery, Nagoya University Hospital was evaluated with ATP-absorbance grade. As a result, the following conclusion was reached:
1. In patients with the same type of opposing dentition, masticatory efficiency of the group with implant-supported bridges was much higher than that of the group with conventional removable dentures.
2. Masticatory efficiency of patients with implant-supported bridges, as in the case of patients with conventional dentures, varied according to the condition of the opposing dentition. It follows, therefore, future research regarding masticatory efficiency needs to be designed so that the patients are classified according to the condition of the opposing dentition.抄録全体を表示PDF形式でダウンロード (456K) -
症例報告ならびに電子顕微鏡学的観察石沢 新, 杉原 一正, 大久保 章朗, 田畑 雅士, 今村 晴幸, 山下 佐英, 仙波 伊知郎1992 年 41 巻 4 号 p. 743-748
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーOdontogenic fibroma is a rare benign tumor of the jaw. It may develop from the dental papilla, the dental follicle, or the periodontal ligament, but the histogenesis of the tumor is controversial. We experienced a case of odontogenic fibroma of the anterior region of the mandible in a 31-year-old male. The tumor was surgically removed under local anesthesia.
The light microscopic findings revealed that the lesion consisted of mature collagen fibers, interspersed with a few small epithelial nests and a few calcified materials resembling acellular cementum. Fibroblastic cells were seen among the complicated mature collagen fibers electron microscopically. The cells of epithelial nests resembled those of the epithelial debris of Malassez.
Histopathological diagnosis was odontogenic fibroma.
The patient had no evidence of recurrence two years after operation.抄録全体を表示PDF形式でダウンロード (13445K) -
道谷 弘之, 金澤 正昭, 谷内 健司, 川上 譲治, 武藤 寿孝, 村瀬 博文1992 年 41 巻 4 号 p. 749-754
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーOsteogenesis imperfecta (O. I.) is a generalized hereditary disease characterized by multiple fracture due to bone fragility, blue sclera, auditory disorder, and dentinogenesis imperfecta. In addition, this disease may show hypermobility of joints, scoliosis, and hemorrhagic diathesis.
W e experienced a rare case of O. I. with temporomandibular joint ankylosis recently. The patient was a 27-year-old male with the chief complaint of severe immobility of the mandible caused by a fracture of the right mandibular condyle in his infancy.
In this case, low position arthroplasty was carried out with an excellent result.抄録全体を表示PDF形式でダウンロード (5513K) -
角南 次郎, 田中 賢治, 谷川 雅洋1992 年 41 巻 4 号 p. 755-757
発行日: 1992/10/10
公開日: 2011/09/07
ジャーナル フリーThis is a report is presented on a case of trigeminal sensory neuropathy in pontine hemorrhage.
The patient was a 47-year-old male who had a chief complaint of left facial sensory neuropathy and visited our department for examination. As for his present illness, about 10 days prior to his initial examination sensory neuropathy developed in the central region of his tongue and as the area of sensory neuropathy gradually expanded to his left facial region, he visited our department. At the time of initial examination, his facial appearance was bilaterally symmetrical, but sensory neuropathy was observed in almost the entire distribution area of the second and third branches of the left trigeminal nerve. Inasmuch as the range of sensory neuropathy was extensive, lesions which might cause such neuropathy could not be radiologically observed in the maxillary and oral region, and the symptom progressively expanded, a diagnosis of central trigeminal sensory neuropathy was made and he was referred to the Department of Neurosurgery of our hospital for detailed examination. Conduct of MRI revealed the presence of hematoma in the left cerebellopontine angle, but cerebral arteriogram could not disclose the presence of any aneurysm or vascular malformation.
His course was thereafter followed at the outpatient clinic. Sensory neuropathy alleviated three months thereafter and MRI performed six months later showed reduction in the lesion size.
As contralateral hemiplegia was not observed in this case with the affected site not included in the pyramidal tract, it was considered to be dorsolateral tegmental hematoma.抄録全体を表示PDF形式でダウンロード (2829K)
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