巻号一覧
41 巻 (1992)
- 4 号 p. 631-
- 3 号 p. 415-
- 2 号 p. 213-
- 1 号 p. 1-
41 巻, 2 号
選択された号の論文の22件中1～22を表示しています
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安田 元昭1992 年 41 巻 2 号 p. 213-233
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーOral epithelial dysplasia is the premalignant change of the oral mucosa, which in some patients undergoes malignant change. But epithelial dysplasia is often present in inflammatory conditions. There is no distinct histological criteria to assess the possibility of malignant transformation.
Keratins make-up the epithelial specific intermediate filament, which has more than 20 subunits ranging in molecular weight between 40 kD and 68 kD and isoelectric values between pH5 and 8. Biochemical studies demonstrated that keratin expression patterns of squamous cell carcinoma are different from its normal counterparts, however keratin profiles of oral squamous epithelia are generally complex even in its normal state. It is necessary to pay attention to the regional difference.
In the present study, the correlations between histological changes, keratin profiles and proliferating activity in the early stages of experimental tongue carcinogenesis were investigated. There were different keratin expression patterns between precancerous epithelial dysplasia and reversible epithelial dysplasia.抄録全体を表示PDF形式でダウンロード (45146K) -
池田 久住1992 年 41 巻 2 号 p. 234-247
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーHematoporphyrin derivatives (HpD) has been utilized as a photosensitizer in photodynamic therapy (PDT). HpD is a mixture of different kinds of perphyrins and whose photoactive component seems to be a dimer or an oligomer.
In this study basic PDT experiments were carried out in vitro and in vivo using the hematoporphyrin oligomers (Hp oligomers) as photosensitizers and pulsed Nd-YAG dye laser as the light source.
In vitro, the Hp oligomers and HpD in 90% methanol solution were compared in their triplet-triplet (T-T) absorption spectra and the life duration of their triplet states. Fluorescence was detected from Raji cells which were coincubated with either Hp oligomers or HpD. Their cytotoxic effect in Raji cells were also compared after laser irradiation.
The intensity of fluorescence was detected in vivo, in normal and tumor bearing areas of C3H/He mouse injected with Hp oligomers 48 hours later. The photonecrotic effects on the tumor were investigated after PDT.
The results obtained are as follows:
1) T-T absorption spectra of the two photosensitizers showed nearly identical patterns. The life duration of the Hp oligomers' triplet state was 3 times longer than HpD.
2) The longer each of the photosensitizers was coincubated, the more it was accumulated in the Raji cells. The cytotoxic effect of Hp oligomers was higher than HpD.
3) Photonecrosis induced by PDT occurred in about 87% of the tumor mass. Histological findings suggested that tumor vasculature is affected by PDT.抄録全体を表示PDF形式でダウンロード (14324K) -
杉本 浩康1992 年 41 巻 2 号 p. 248-257
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーThe submandibular gland is innervated by postganglionic sympathetic, parasympathetic, and sensory nerve fibers.
Although acetylcholine and noradrenaline are well known as neurotransmitters in the autonomic nervous system, many neurotransmitters such as substance P (SP), calcitonin gene-related peptide (CGRP), vasoactive intestinal peptide (VIP) and others were recently discovered in submandibular gland. The role of these neurotransmitters in the salivation are not well known.
In the present study, the nerve fibers immunoreactive for SP and CGRP and their coexistence were observed in the rat submandibular gland. Furthermore, the effects of these neuropeptides on salivary flow, α-amylase release, blood flow in the submandibular gland and systemic mean arterial blood pressure were observed.
The nerve fibers immunoreactive for SP or CGRP were detected in the acini and were also detected in the interlobular connective tissue beside the large duct and the blood vessel. Almost all of these nerve fibers were immunoreactive for both SP and CGRP. Nerve fibers immunoreactive only for SP were detected to some extent but those only for CGRP were not.
SP increased salivary flow and blood flow in the submandibular gland, and this effect of SP on salivation was not inhibited by atropine or trimethaphan. SP did not increase α-amylase release. On the contrary, CGRP increased a-amylase release but did not increase salivary flow and blood flow. The increased α-amylase release by CGRP was inhibited by propranolol. Both SP and CGRP decreased the systemic mean arterial blood pressure.抄録全体を表示PDF形式でダウンロード (6240K) -
われわれが開発したHAP顆粒 (Kobeceram) と他のHAP顆粒との検討梅田 正博, 岩田 耕三, 栄田 和, 武 宣昭, 内藤 勲, 高橋 伸彰, 島田 勝弘, 栗岡 一人, 川本 博男, 寺延 治, 島田 桂 ...1992 年 41 巻 2 号 p. 258-267
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーThis paper describes the effects of chemical composition, shape, solubility behaviour on the osteoconduction and stability of hydroxyapatite (HAP) granules by the histological investigation for grafting four types of HAP granule (Apaceram®, Bonetite®, Actoceram® and Kobeceram which we have developed) into rabbit tibias. The following results were obtained.
1. X-ray diffraction showed that Apaceram® was the single phase of HAP. Bonetite® and Actoceram ® contained a small amount of free CaO. Kobeceram contained β-TCP.
2. Apaceram® and Actoceram® have many micropores smaller than 10 μm in diameter. Bonetite® has no pores on the surface. Kobeceram® has multinuclear granules with continuous pores ranged from 30 to 200 μm in diameter.
3. The solubility of Ca and P in isotonic NaCl solution was influenced by the relative surface area and the Ca/P molar ratio of HAP granules.
4. Each granule in particular Apaceram® and Kobeceram showed significant osteoconduction.
5. Histological examination of the 6-month specimens revealed bone resorption among HAP granules in the Apaceram® and Actoceram® groups although there was little resorption in the Kobeceram an Bonetite® groups.
6. The infiltration of imflammatory cells was observed in the 6-month specimens of the Actoceram® group.抄録全体を表示PDF形式でダウンロード (13504K) -
鈴木 浩之, 橋本 賢二1992 年 41 巻 2 号 p. 268-274
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーWe investigated calcification under the condition of long term culture of fibroblasts derived from gingiva. Human gingival fibloblasts (OK-F, SY-F) were cultured in a Dulbecco's Modification Eagle's Medium supplemented with 2 mM L-ascorbic acid 2-phosphate, 2 mM α-glycerophosphate, 100 U/ml penicillin, 100μg/ml streptomycin and 10% foetal bovine serum. The cell sheet consisted of epithelial- like and spindle cells, app. at 14 days cultivation.
These cells had similar characteristics to the osteoblastic cells (KY-20, SN-29, YT-28) that we previously reported. These gingival fibloblasts had the ability to calcify. Osteocalcin and alkaline phosphatase activities were also detected. But the initiation of calcification was later, the level of osteocalcin and alkaline phosphatase activities was lower than these of osteoblastic cells.
These data suggest the initiation time of calcification, Gla protein, and alkaline phosphatase activities were available to discriminate between fibroblasts and osteoblasts.抄録全体を表示PDF形式でダウンロード (8017K) -
角田 左武郎, 戸羽 一, 真鍋 真人, 南雲 正男1992 年 41 巻 2 号 p. 275-280
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーγ-carboxyglutamic acid-containing protein (bone gla protein: BGP or osteocalcin) was one of the major non-collagenous proteins in mineralized tissues. It has high affinity for calcium and is produced by osteoblasts. At present, however, the biological role of BGP in mineralized tissues is still obscure. The purpose of this study is to investigate BGP levels of various mineralized tissues obtained from human jaws and teeth. Then, the relation between BGP and calcification was estimated.
The results revealed that although BGP were detected in all mineralized tissues, the levels were different in each tissue. The highest level was observed in bone torus which was resected from torus palatinus or torus mandibularis. The levels of alveolar and cortical bones were relatively higher than that of cancellous bone. While BGP was also present in impacted wisdom teeth and odontoma, these levels were very low. Furthermore, investigating the relationship between BGP levels and calcium contents, or alkaline phosphatase activity using bone torus, positive correlation was found between BGP levels and calcium, but not between BGP levels and alkaline phosphatase. Considering the role of alkaline phosphatase which relates to the onset of calcification, these results suggested that BGP might be associated with the advancement of calcification.抄録全体を表示PDF形式でダウンロード (669K) -
骨および腫瘍シンチグラムの検討鄭 漢忠, 戸塚 靖則, 臼井 康裕, 喜田 正孝, 福田 博, 進藤 正信, 飯塚 正, 雨宮 璋, 滝波 修一, 山崎 岐男1992 年 41 巻 2 号 p. 281-289
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーW e investigated whether the bone and 67Ga scintigraphy could add any new information to radiographical findings in detecting mandibular involvement of squamous cell carcinoma of the lower alveolus. W e examined 14 primary cases who received a mandibulectomy.
In the present study, it was suggested that the bone scintigraphy could indicate the early stage of the bone involvement of the carcinoma, and that the presence of a third-degree hot spot of the bone scintigraphy likely indicates the infiltrative growth of the carcinoma. It was also suggested that it is difficult to diagnose the extent of the tumor invasion by radiography in patients who show the third-degree hot spot without central photondifficient area. These results suggest that the bone scintigraphy could give us additional informations to the radiographical findings for diagnosing the extent of bone involvement of carcinoma.
On the other hand, it was suggested that 67Ga scintigraphy could not give us any additional informations for diagnosing the extent of the mandibular involvement of the squamous cell carcinomas in the lower alveolus.抄録全体を表示PDF形式でダウンロード (11925K) -
中山 勝憲1992 年 41 巻 2 号 p. 290-300
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーIn order to clarify the relationship between palatal development and distribution and transition of cytokinetic activity in the palatal shelf during secondary palate formation, modulation of cytokinetic activity of epithelial and mesenchymal cells in the palatal shelf were studied at 14.5 to 18.5 gestation days in normal and vitamin A treated rat embryos by means of Bromodeoxyuridine (BrdU) labeling and immunohistochemical staining. The results were summarized as follows.
1. The palatal shelf reorientation from vertical to horizontal direction took place at 16.5 and 17.5 gestation days in normal and cleft embryos, respectively.
2. The rate of BrdU labeled cells was highest one day before the reorientation in both groups.
3. Before the onset of palatal shelf reorientation, an accumulation of BrdU labeled mesenchymal cells occurred in the nasomedial region in the palatal shelves in both groups.
4. During the process of medial extension of palatal shelves, the increase in the total width of the palatal base was larger in the cleft group than in the normal group.
Among other parameters, these data may suggest an intimate correlation between the cytokinetic activity and the vertical to horizontal reorientation of palatal shelves, and provide further support to the hypothesis that the palatal shelf reorientation is remodeling due to transformation rather than rotation of the palatal shelves. The discrepancy between the total width of palatal base at the time of palatal shelf reorientation and that of palatal shelves may be related to cleft palate generation.抄録全体を表示PDF形式でダウンロード (15575K) -
山口 万枝, 水野 明夫, 秋山 順史, 片山 貴之, 松下 文彦, 藤澤 孝司, 北川 善政, 式守 道夫, 橋本 賢二1992 年 41 巻 2 号 p. 301-307
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリー1 hree cases of “plunging ranula” are reported. In these cases treatment consisted of total removal of the sublingual gland and marsupialization of the cyst by an intra-oral approach. The common clinical findings in all three cases were as follows. Elastic soft and fluctuating swelling in the submandibular region was seen without pathologic findings in the floor of the mouth. But when the submandibular mass was squeezed, a slight shelling ballooned up in the floor of the mouth. On release, it returned to normal again. The cysts contained thick, viscid, stringy, straw-colored and semi-transparent mucous.
The above-mentioned operative procedure was thought to be a more reasonable treatment due to consideration of reported anatomical findings about mylohyoid herniation.抄録全体を表示PDF形式でダウンロード (12603K) -
木高 亘志, 佐野 和生, 井口 次夫, 藤田 修一, 岡邊 治男1992 年 41 巻 2 号 p. 308-315
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーWe reported a case of acinic cell, tumor arising from the soft palate in a 26-year-old woman. The lesion, an elastic soft mass, measured 2.0×2.0×1.5 cm and was excised under local anesthesia. Microscopic and ultrascopic examination revealed four cell types: serous acinic type, clear, vacuolated, and intercalated duct-like cells. And the margins of the tumor were free from neoplastic involvement, and atypism and mitotic activity were not observed. Regarding the histogenesis of the tumor, we support the hypothesis of multipotential duct cell histogenesis, because we identified intercalated duct-like cells and this tumor occurred in pure mucous glands. 36 months after the operation, the patient demonstrated no recurrence or metastasis.抄録全体を表示PDF形式でダウンロード (23628K) -
松井 義郎, 大野 康亮, 田代 恒久, 吉田 広, 山下 夕香里, 今井 智子, 道 健一, 大谷 俊一, 秦 博文, 積田 正和, 山縣 ...1992 年 41 巻 2 号 p. 316-321
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーIt is said that palatal lift prosthesis (PLP) is useful for activation of the velopharyngeal function. And it typically consists of a palatal portion with hooks that attach to the patient's teeth and a posterior extension that elevates the soft palate to the posterior pharyngeal wall, thereby producing a mechanical obstruction of nasopharynx. So the retention of PLP becomes difficult in edentulous patients.
We describe here the application of hydroxylapatite-coated implants (Integral®) with magnetic attachments for the retention of PLP in the management of two edentulous cleft palate patients.
After the operation speech function and velopharyngeal closure were satisfactory in both cases.抄録全体を表示PDF形式でダウンロード (7257K) -
1. 当科における臨床統計的検討栗田 浩, 腰原 高志, 倉科 憲治, 岩原 謙三, 荻場 明子, 小川 浩樹, 小木曽 暁, 田村 稔, 峯村 俊一, 小谷 朗1992 年 41 巻 2 号 p. 322-330
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーClinico-statistical analysis of medically compromised patients who had dental and oral surgical management was reported.
There were 1, 998 medically compromised patients among 7, 988 outpatients who visited our department in the period of July, 1986 to June, 1990, an incidence of 25.0 per cent. The mean age of the patients was 52.4 years, older than that of all outpatients.
Cardiovascular diseases were the most common (35.%). Other diseases consisted of digestive organs' disease (17.2%), hematological disease (9.8%), respiratory disease (9.6%), and others (27.8%). There were 258 patients who had a history of allergy for drugs, and 62 patients who were infected with HBV, and so on.
The most common disease in children was hematological and in the elderly was cardiovascular.
Seventy two point four per cent of the patients was refered to us from other departments of our hospital.
A variety of dental and oral surgical procedures were done on these patients. More than half of the patients had a dental anesthesia and underwent the treatments which might cause bleeding and/or infection.
Complications associated with our treatment occured in 26 patients (1.4%).抄録全体を表示PDF形式でダウンロード (1105K) -
安藤 博史, 日比 五郎, 木造 博貴, 杉浦 直樹, 奥井 寛三, 辻川 孝昭, 岡 達1992 年 41 巻 2 号 p. 331-342
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーW arthin's tumor is a relatively uncommon lesion predominantly found in or around the parotid gland. The distinctive character of this tumor is the unusual association of lymphoid and epithelial tissue that has a tendency for easy fromation of multiple cysts.
Three cases of Warthin's tumor are reported. They had been refered to our department because of rapid growth of the tumor, developing in 2 M, 5 M, and 12 M, respectively. Etiology of the rapid growth remained uncertain, although accelerated retention of the cystic contents was assumed to be one of the causes. The tumors were located within the gland, occupying most of the lower pole. Staining the glandular tissue with Indigocarmin®, adversely introduced via Stensen's duct, easily identified the capsule and surgical removal of the tumor was carried out uneventfully. Staining the glandular tissue thus proved extremely useful in avoiding damage to the VII cranial nerve and minimizing damage to the gland itself.
Among various kinds of preoperative examinations, CT scans as well as 99mTc scintigraphs have shown to be helpful for a tentative diagnosis. Clinical diagnosis would be possible preoperatively if lesions were thoroughly examined with aspiration biopsy supporting the findings of these two methods.抄録全体を表示PDF形式でダウンロード (25858K) -
末井 良和, 藤田 實, 田口 明, 山田 純, 和田 卓郎1992 年 41 巻 2 号 p. 343-350
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーOne hundread and fifty three mandibular fractures of youngsters below 15 years old were studied with respect to sites, frequencies, and involved tooth germs. An average of fracture lines was 1.7. The condylar process was the most frequent site, followed by the canine and incisor regions. In the body of the mandible, the frequency of each site varied in correlation to age: that is, fractures were focused upon the incisor and/or canine areas in those under 8 years old, and dispersed to the premolar and molar regions in the elders. Tooth germs of incisor and canine were most frequently involved in 1-7 year old patients. In elder patients, the frequency of involvement of these tooth germs decreased and that of the posterior tooth germs increased. From these findings, it was suggested that the alteration of predisposing sites of the mandibular fractures in youngsters might be attributed in some degree to the developmental stage of permanent tooth germs.抄録全体を表示PDF形式でダウンロード (997K) -
武藤 寿孝, 山田 雄, 小西 亮, 金澤 正昭, 麻生 智義, 中出 修, 大内 知之, 賀来 亨1992 年 41 巻 2 号 p. 351-356
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーWe experienced two cases of inflammatory papillary hyperplasia of the hard palate, which had been rarely reported in Japan. The first case was a 53-year-old women, the second a 49-year-old women. The clinical and pathological features were as follows:
1. The patients wore the dentured day and night.
2. Characteristics in the clinical picture were slightly raised, raspberry-like papillary or nodular lesion.
3. Histologically, the lesion showed numerous papillary growths that were covered by parakeratotic stratified squamous epithelium with an inflammatory infiltrate in the subjacent connective tissue.抄録全体を表示PDF形式でダウンロード (9874K) -
熊谷 正浩, 越後 成志, 五十嵐 隆1992 年 41 巻 2 号 p. 357-365
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーA case of Nevoid basal cell epithelioma syndrome is presented. The patient, 55-year-old male, who was treated in the mandibular region twenty years ago and became aware of the recurrence of the cyst, had many features of this syndrome. During follow-up, a thyroid gland malignant tumor was recognized. The reason the mandibular cyst recurred after a long period without symptoms is regarded an anatomical feature of the coronoid process of the mandible and infratemporal fossa where the cystic region can swell without attracting attention. Serial systemic tumor screening is necessary for patients diagnosed with this syndrome, for several kind of malignant tumors, not only the main feature, basal cell carcinoma, are likely to occur as seen in this case.抄録全体を表示PDF形式でダウンロード (14155K) -
石神 哲郎, 杉原 一正, 吉嶺 秀次, 今村 晴幸, 新屋 俊明, 有村 健二, 石沢 新, 藤村 卓生, 山下 佐英1992 年 41 巻 2 号 p. 366-372
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーThis article described a case of hypercementosis associated with acromegaly in a 56-yearold woman.
The patient was referred to us with a complaint of pain at the left upper first molar tooth. She exhibited acromegaly whose serum growth hormone level was extremely high. And, radiographically, bilateral upper molar teeth showed the thickening and a club-shaped from of the root. The tooth was extracted because of the apical lesion and mobility.
Histopathologically, the specimens of the tooth showed a typical advanced stage of hypercementosis.
A few reports described hypercementosis associated with acromegaly. We speculated that acromegaly had played a role in the pathogenesis of hypercementosis in this patient.抄録全体を表示PDF形式でダウンロード (12057K) -
後藤 圭也, 白土 雄司, 森藤 政代, 樋口 勝規, 後藤 多津子1992 年 41 巻 2 号 p. 373-380
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーA 27-year-old female was referred to our clinic complaining of enlargement of the left cheek and masticatory disturbance due to loss of left lower and right upper molars.
Clinical examination revealed a narrow vertical distance at the posterior molars bacause of maxillary excess on the left side and mandibular excess on the right side. As prosthetic appliance was inapplicable, surgical correction was adopted.
After pre-surgical orthodontic therapy, the unilateral maxillary posterior segmental osteotomy was performed on the left side, on the right side shaving of upper alveolar process was conducted.
On the left side, the dual approach from both the buccal and the palatal areas was carried out in one stage and the segment was fixed using two titanium mini-plates.
After operation, a temporary hypertrophy of maxillary sinus mucosa was observed. However, the usually reported postoperative complications such as relapse and disturbance of the segment or the teeth were not seen.抄録全体を表示PDF形式でダウンロード (15246K) -
村田 行秀, 平野 吉雄, 小林 知視, 大西 誠, 真田 浩一, 別所 和久, 田川 俊郎1992 年 41 巻 2 号 p. 381-388
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーWe reported a case of histiocytosis X which was diagnosed as having changed from Letterer-Siwe disease to Hand-Schuller-Christian disease.
The patient was a 4-year-old male and had some lesions of the left maxillary gingiva, skin, and right orbita. But he had no signs of diabetes insipidus and no lesions of the cranium.
He was treated with a combination of chemotherapy of VLB, CPM, VP-16 and DEX in the pediatrics department. Since the symptoms were worse after the 4 th course, the drugs were changed to CDDP, ACR, VLB, CPM and DEX. The symptoms stabilized.
In the electron micrograph of the lesions on the gingiva, “Birbeck granules” were observed in the cytoplasma of tumor cells.抄録全体を表示PDF形式でダウンロード (16384K) -
臨床および統計学的観察佐木 宏吉, 市原 秀記, 阿部 一雄, 西村 悟, 奥田 孝, 半田 祐二朗, 立松 憲親, 堀 悟, 岡 伸光1992 年 41 巻 2 号 p. 389-394
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーSupernumerary impacted teeth in the anterior region of the maxilla (SIT) found in 40 clinical cases in the 5-55 year old (average: 12.1 years old) age group were reviewed in this paper together with an analysis of clinical appearances. In this survey, it was disclosed that 62.5% of the cases were diagnosed to have only one SIT, whereas the rest of them was found to have two. Direction of the dental crown of the SIT was also examined and revealed to be inverted in 49% of the cases. Operation was carried out with palatal side approach in 82.5% of the cases. Sexual predilection of the occurrence was also indicated in this survey with a fact that 70% was occurred in males. Discussion was made particularly on the relationship between the origin and favorite site of SIT.抄録全体を表示PDF形式でダウンロード (3058K) -
角田 博之, 海老原 務, 永井 哲夫, 田中 陽一, 小川 哲平1992 年 41 巻 2 号 p. 395-400
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーWe report here a rare case. A 54-year-old female visited our department. Her chief complaint was multiple tumors on the dorsum of the tongue. This was diagnosed as a rare case of amyloidosis associated with plasma cell dyscrasia.
(1) Amyloid was disclosed by light and electron microscopy in biopsied tissues. The amyloid-fibril protein was thought to be amyloid light chain protein, and immunostained sections suggested amyloid A protein deposition.
(2) Clinical laboratory tests disclosed diminutions in total protein and gamma globulin. Kappa Bence-Jones protein was detected in the M-component from electrophoresis of concentrated urine and serum. No rheumatoid factor or antinuclear antibodies were detected.
(3) Inasmuch as the ratio of plasma cell in the bone marrow was 9.8 % and was below the criteria of Durie-Salomon for multiple myeloma, this was diagnosed as plasma cell dyscrasia.抄録全体を表示PDF形式でダウンロード (5248K) -
大野 康亮, 中村 篤, 山下 夕香里, 大沢 毅晃, 森 紀美江, 道脇 幸博, 秋月 弘道, 斎藤 健一, 吉田 広, 道 健一1992 年 41 巻 2 号 p. 401-413
発行日: 1992/04/10
公開日: 2011/09/07
ジャーナル フリーThree cases of reconstructed soft palate and oropharyngeal defects with free radial forearm flap are presented. Three male patients of forty-six (case 1) and fifty-one years (case 2, 3) of age had wide resection including radical neck dissection for advanced squamous cell carcinoma in the left retromolar trigone in case 1, in the right buccal mucosa in case 2 and in the oropharynx in case 3. All patients received surgical reconstruction using the forearm flap in the large defect of the oral mucosa and oropharynx. Postoperative speech function and velopharyngeal closure are satisfactory in all cases, using in combination with speech appliance. Consequently, the free radial forearm flap with speech appliance is considered to be suitable and functional for treating soft palatea nd oroph-aryngeal defects in which rehabilitation with conventional flaps or maxillofacial prosthesis is difficult.抄録全体を表示PDF形式でダウンロード (8779K)
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