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Volume 44, Issue 4
Displaying 1-19 of 19 articles from this issue
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Hironari KAWAGOE, Masahiro UMEDA, Toru NAKATANI, Naruki NISHIMATSU, Yo ...1995 Volume 44 Issue 4 Pages 563-568
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSFive oral squamous cell carcinomas, which have been maintained in the subcutaneous tissue of nude mouse, were transplanted orthotopically into the tongue of nude mouse. These tumors were transplanted successfully in 16 of 18 mice. In contrast to the expansive proliferation of the subcutaneously transplanted tumor, the tongue tumor showed invasive proliferation with no surrounding capsule. Lymph node metastasis was observed in six of 16 mice. These findings indicate that this experimental model is useful for studies of invasion and lymph node metastasis of oral cancer.View full abstractDownload PDF (15430K) -
Measurement of Strain Under Application of Bone Chisel-Shuuichi FUKUNAGA, Jun SHIMADA1995 Volume 44 Issue 4 Pages 569-583
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSExperimental studies using airdried human mandibule were performed to define the mechanism of the development of fractures of the mandibular angle region.
It can be concluded that, by removal of bone during the extraction of an impacted third molar, it is important to try not to expose the tooth crown or to preserve the external oblique region for the prevention of a mandibular fracture. If these things have been done, the subsequent procedure, that is, the application of elevator, must be done very carefully. Furthermore, in the case of the application of bone chisel in the direction of the lower mandibular border, this procedure needs to be performed carefully to avoid fracturing of the mandibular angle region, because the amount of bone to be removed is large in such a case.View full abstractDownload PDF (12088K) -
Toshiyuki KAWAKAMI, Noriyuki TAKEI, Motoyoshi ANTOH, Hiromasa HASEGAWA ...1995 Volume 44 Issue 4 Pages 584-588
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSAn embedding medium “Celloidin”, supplied by T. Co., was used for histological sections including hard tissues. In Japan, however, “Celloidin” was not obtainable from T. Co. because it is no longer produced. Therefore, it was decided to develop a new histological embedding medium replacing “Celloidin”. After trial and error, a new embedding medium “Shiojirin-E”, made chiefly of cellulose nitrate, was produced. The name of “Shiojirin” came from the address of Matsumoto Dental College. The composition is: cellulose nitrate 10.00 g, ethanol 42.85 g, diethyl ether 42.85 g, and others 4.30 g (Total 100.00 g). When the specimens are not so big, it is easy to obtain 3-5 micronthick-sections like paraffin sections. These results indicate that the new developed “Shiojirin -E” is a useful embedding medium for sections including hard tissuesView full abstractDownload PDF (5297K) -
Munetaka NAITOH, Masaru SHIOJIMA, Atsushi KIKUCHI1995 Volume 44 Issue 4 Pages 589-595
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSFindings of mandibular canal close to mandibular lesions (46 cases and 53 places in total), obtained by panoramic radiography and computed tomography, were examined. The mandibular lesions extended between premolar and mandibular ramus region and were well-defined by radiolucency in panoramic radiographic findings. The 46 lesions in this study were finally diagnosed as ameloblastoma in two cases, radicular cyst in nine cases, residual cyst in one case, primordial cyst in six cases, dentigerous cyst in 23 cases and simple bone cyst in five cases.
The results are as follows:
1. In panoramic radiographic findings, conditions of mandibular canal were classified as seven types according to the relation to the lesion and the displacement of the mandibular canal. In 16 of 53 places, mandibular canal was displaced and overlapped at the bottom of the radiolucency, whereas in 15 places mandibular canal did not appear.
2. In axial CT images based on 3-mm thick-slices, in 38 out of 46 cases mandibular canal was welldefined. In I6 of 38 cases mandibular canal was buccolingually displaced
3. In the MPR (multiplanar reformation) images reconstructed from axial CT, the positions of mandibular canal to the lesion were classified as six types. In 30 of 53 places, mandibular canal was positioned below the lesion.
4. In nine places, MPR images showed the mandibular canal below the radiolucency as panoramic radiographic images did.View full abstractDownload PDF (3791K) -
Hiromi KOYANO, Yoshinori JINBU, Tadahide NOGUCHI, Yoko AKASAKA, Hideo ...1995 Volume 44 Issue 4 Pages 596-602
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSTongue dorsal epithelia exhibit a highly specialized structure. In order to characterize biological features of tongue dorsal epithelia, expression pattern of cytokeratins and adhesion molecules in human normal tongue were analyzed. Positive reaction with monoclonal antibodies for cytokeratins AE 3, AE 5, No.5/6, and 903 was observed in the basal cell layer, the spinous cell layer and the keratinized layer, while CK 1 stained the basal cell layer and the spinous cell layer. Positive reaction with No.4 and No.13 was observed in the spinous cell layer of the interpapillal region, but no reaction was seen in the papillal region. The expression of integrin a2 was observed at the cell membrane of the basal cell layer and the spinous cell layer, and those of as and as were observed at the cell membrane of the basal cell layer in the interpapillal region. However, positive reaction with anti-a5 antibody was also seen in the spinous cell layer as well as basal cell layer in the interpapillal region. The localizations of as and 484 were demonstrated at the basal cell surface of the basal cell layer. The expressions of E-cadherin and desmoglein were observed at the cell membrane of the basal cell layer and the spinous cell layer, while that of P-cadherin in the basal cell layer only. Our results clearly demonstrated that there are significant differences in the expression patterns of cytokeratins and adhesion molecules between the region of papillae and interpapillal epithelia.View full abstractDownload PDF (7433K) -
Hypoglossal Nerve and Tongue Muscle in the Horse Musk Shrew (Suncus murinus) by Morphological StudiesKazutaka SUYAMA1995 Volume 44 Issue 4 Pages 603-612
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSSequential effect of nerve transection and regeneration on motoneuron (MN) and muscle fiber (MF) was examined in the present study, using an HRP method. The morphological changes of the hypoglossal MN and logitudinal tongue MF, after transection or excision of the right hypoglossal nerve in the Horse musk shrew (Suncus murinus) was observed. In the transection group, reinnervation to the muscle started about 1 week and finished about 10 weeks after surgery, and both MN and MF were considered to be regenerating since 4 weeks postoperatively. In the excision group, reinnervation hardly occurred and all of the experimental results showed degenerative tendencies. Though decrease of MN number in 2-4 weeks after excision indicated rapid deterioration of regenerative capacity of MN which lost its target, decrease of MF number appeared since 15 weeks post operatively. This matter suggested a possibility of muscle regeneration by the surgical technique (e. g. nerve anastomosis) even if muscle atrophy progresses after a long time of nerve injury.View full abstractDownload PDF (10673K) -
Kohjiroh MATSUMOTO, Toshikazu NAGATO, Hiroaki TANIOKA1995 Volume 44 Issue 4 Pages 613-621
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSTo elucidate the trophic function of neurons on redifferentiation of the denervated fungiform papillae, unilateral axonotmesis (nerve crush) of the chorda tympani-lingual nerve of the rat was performed at day 1 and weeks, 1, 2, 3, 4, 7 and 10 after birth by using watchmakers forceps. Specimens were obtained at weeks 6 and 8, and months 3 and 4 after nerve crush for examination with scanning electron microscope. As revealed by nerve transection experiment, process of morphological changes of the fungiform papilla consisted of degeneration and redifferentiation phase. Sequential alterations of the morphology of redifferentiating fungiform papillae were divided into 4 stages:(1) quasifiliform papillae indistinguishable from normal filiform papillae ;(2) filiform-like papillae similar to, but distinguishable from, the normal filiform papilla ;(3) undifferentiated fungiform papillae with small shape and no taste pore ;(4) redifferentiated fungiform papillae same as the normal fungiform papilla. Using these criteria, the number of each type of fungiform papillae was determined for a given sampling area, and compared with those of nerve transection experiment. Appearance of the redifferentiated fungiform papilla in axonotmesis (nerve crush) experiments was much earlier than in nerve transection experiments. All of fungiform papillae denervated at 1 day after birth changed to the quasi-filiform papilla and did not return to the normal fungiform papilla. Some of fungiform papillae denervated at weeks 1 and 2 after birth changed to the quasi-filiform papilla and remains changed to the filiform.-like papilla. According to extension of the period after nerve crush, redifferentiated fungiform papillae were increased and quasi-filiform papillae were decreased in number. Most fungiform papillae denervated at 3 or more weeks after birth changed to the filiform-like papilla and then returned to the normal fungiform papilla. These findings suggest that (1) axonotmesis is better than nerve transection in regard to regeneration of axon ;(2) there are two kinds of quasi-filiform papillae concerned with redifferentiation ability ;(3) ability to redifferentiate is determined by degree of maturation of the fungiform papilla at denervation and regeneration speed of the damaged axon.View full abstractDownload PDF (14567K) -
Yukihiko KINOSHITA, Naritaka MIZUTANI, Yuji YOKOMIZO, Shin-ichi FUKUOK ...1995 Volume 44 Issue 4 Pages 622-627
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of spindle cell carcinoma of the oral cavity in a 78-year-old woman is reported together with the immunohistochemical and electron microscopic findings. She had a peduculated tumor mass measuring 30 X 45 mm in the lingual mucosa on the right side of her mandible. The tumor was diagnosed as spindle cell carcinoma by histopathological examination of biopsy specimen, and a segmental resection of the mandible with the tumor mass was performed.
Histologically, the tumor contained two kinds of structural patterns: well-differentiated squamous cell carcinoma, and a sarcomatous appearance of diffusely proliferating spindle-shaped tumor cells with a high frequency of mitotic figures. The sarcomatous areas were closely associated with the areas of squamous cell carcimona. Immunohistochemically, the tumor cells of sarcomatous areas were positive for keratin, epithelial membrane antigen (EMA) and vimentin, and negative for desmin and actin. Electron microscopy revealed that some of the spindle-shaped tumor cells were connected with desmosomes and a few of them contained tonofilaments. Three months later, the patient had a local recurrence. Radiotherapy was performed, but it failed to control the malignant growth.
The patient's general condition deteriorated gradually, and she died seven months after surgery.View full abstractDownload PDF (9644K) -
Toshirou KONDOH, Kazutoshi KAMEI, Mari HAGA, Kaoru KOBAYASHI, Motohiro ...1995 Volume 44 Issue 4 Pages 628-638
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThis study was designed to investigate osteoarthritic changes (i. e., degenerative changes of the articular cartilage) associated with internal derangement of the temporomandibular joint. One hundred seventy-one joints in 129 patients who had a diagnosis of anterior disc displacement without reduction were studied by image analysis (tomography and MR imaging) and arthroscopy. The tomographic and MR findings were compared with the arthroscopic findings of the upper joint compartment to assess the degree of correspondence between these diagnostic techniques. The following results were obtained.
1) There was little correlation between the prevalence of sign of cartilage degeneration (fibrillation, ulceration, bony destruction) at the articular surface of the eminence and the presence or absence of whole bony deformation as evaluated by tomographic findings. There was also little correlation between the degree of disc displacement on MR and arthroscopic findings. There was significant correlation between the presence of disc deformation and arthroscopic findings which revealed the articular surface of the eminence (p<0.05, x2=5.119). Analysis of the relationship between the presence of disc deformation and arthroscopic findings revealed the articular surface of the eminence to be pathological in 29 % of cases without MR evidence of disc deformation. Cartilage degeneration was seen arthroscopically in 56 % of cases with disc deformation.
2) There was significant correlation between the presence of disc deformation and arthroscopic findings which revealed the disc surface (p<0.01, x2=12.855). Analysis of the relationship between the presence of disc deformation and arthroscopic findings revealed the surface of the disc to be pathological in only 7 % of cases without MR evidence of disc deformation. Disc degeneration was seen arthroscopically in 59 % of cases with disc deformation.
The above findings suggest that the frequency of osteoarthritic changes in the upper joint compartment is related to disc deformation.View full abstractDownload PDF (8099K) -
Itsu TADA, Takayoshi TSUBAI, Yoshikage HIGASHI, Masakazu ISHIKAWA, Yut ...1995 Volume 44 Issue 4 Pages 639-643
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSMost abnormal tubercles observed in the anterior portion generally occur in the lingual surface. Those tubercles, however, rarely appear in the labial surface.
Here is a case of a 15-year-old male with an abnormal tubercle in the labial surface of maxillary lateral incisor tooth.
His abnormal tubercle appearing at the left second lateral incisor tooth had a conic shape and it was 9.3 mm in length and 5.7 mm in width. As for the aspect of the proximal surface of the abnormal tubercle, the curvature of the labial surface was nearly constant from the cervical part to the top, which was about 2 mm from the labial surface of the tooth.
X-ray radiography revealed that the basement of the abnormal tubercle was positioned around the cervical neck of the lateral second incisor tooth. Further, a broad zone with an increased density, which indicated a composition of enamel, was noted around the abnormal tubercle. Although the morphology of the root canal of this case was similar to that of a normal one for the radicular pulp cavity, the coronal cavity was unclear because of the presence of an abnormal tubercle.
From these results, it was assumed that the occurrence of the abnormal tubercle might be caused by morphological alteration in the basel membrane, constructing a part of tooth germ which would form the border between the enamel and the dentin, in an early stage of the development of tooth germ.View full abstractDownload PDF (3400K) -
Yuka NOMURA, Kazunori YONEDA, Tetsuya YAMAMOTO, Eisaku UETA, Akihiko O ...1995 Volume 44 Issue 4 Pages 644-651
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSOral lichen planus (OLP) was clinically examined in 150 patients treated in our clinic during the last 10 years. The buccal mucosa was most predisposed to OLP, followed by the tongue, lip and palate. Erosive ulcerative type was most common (184 sites) being complicated with candidiasis in 19 patients, and reticular, leukoplakic and erythroplakic lesions were observed at 166, 28 and 14 sites, respectively. Considering the severity of the inflammation, topical prednisolone (PSL), which was ionophoresed in most cases, was primarily applied to 133 cases and oral administration of PSL was tried in 17 cases with widely distributed OLP. In cases complicated with candidiasis, an antifungal agent amphotericin B was prescirbed for gargling. In addition, an antiallergic drug azelastine hydrochrolide (Azeptin) was orally used in 8 patients who exhibited relatively severe contact pains. As the result, disappearance of the discomfort was obtained in 88.7% of locally treated cases within about 3 weeks after the start of treatment. No relationship between the clinical types and the therapeutic effects was observed, however, the response in leukoplakic lesions was weak; nevertheless, all Azeptin-prescribed cases became free from discomfort. Lesions in 12 cases, which were unsatisfactorily improved by topical PSL, were secondarily treated with oral PSL for about 1 month, and all of them were improved. Of 17 cases which received oral PSL originally, 2 cases did not show any improvement. Some lesions of originally severe cases became symptomatic again, but recurring OLP responded sufficiently to secondary treatment with PSL. These results indicate that ionophoresed topical PSL is very useful for OLP and oral PSL should be limited to severe cases and that treatment of OLP complicated with candidiasis and leukoplakic OLP should be revised.View full abstractDownload PDF (5816K) -
Bromodeoxyuridine and α-smooth Muscle Actin ImmunostainingYuji NARIMATSU, Kazuo SANO, Shinichi YOSHIDA, Narihiro KAMASAKI, Tsugi ...1995 Volume 44 Issue 4 Pages 652-657
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSA case of gingival hyperplasia induced by nicardipine (NIGH) was presented. The patient was a seventy-four-year-old Japanese woman. The swelling of the gingiva was reduced after changing the drug, tooth brushing instruction and scaling without gingivectomy.
The hyperplastic gingiva, as compared with phenytoin-induced gingival hyperplasia (PIGH) and normal gingiva (NG), was investigated histologically and immunohistochemically. By means of bromodeoxyuridine (BrdU) immunohistochemistry, synthetic phase cells were identified in the basal and suprabasal layers in the epithelium. However, BrdU labeling indices showed no remarkable difference between NG and hyperplastic gingiva. Therefore, it was suggested that proliferation of the connective tissue mainly results in gingival hyperplasia.
Several myofibroblasts, detected by a-smooth muscle actin (α-SMA) immunohistochemistry, were observed in the connective tissue of NIGH and one of PIGH. Number of the a-SMA positive vessels in the lamina propria of NIGH was higher than that in PIGH and NG. Diameter of arteries in the lamina propria of NIGH was bigger than that of the other cases. These findings suggested possible relation of the myofibroblasts to manifestation of NIGH and hypothesis whose effect of the calcium-channel blocker on the vessels in marginal gingiva might result in NIGH.View full abstractDownload PDF (12015K) -
Fumio KINOSHITA, Satoru OKAZAKI, Masahiro MICHIZAWA1995 Volume 44 Issue 4 Pages 658-661
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSIn a 56-year-old male with aplastic anemia of a 10-year history, a highly differentiated squamous cell carcinoma developed in the gingiva of the left mandibular molars (T3N0M0). Chemotherapy that causes marked bone marrow suppression was avoided; the surgery was limited to marginal resection of the mandible and dissection of the upper neck region to minimize the surgical damage, and radiation therapy (50 Gy) was performed postoperatively. The platelet level was maintained at 60, 000/μl or above for several days by preoperative platelet transfusion. It decreased to 10, 000/μl after the end of the radiation therapy but recovered gradually. The white blood cell count could be maintained at 3, 000/μl or above, and red blood cell count at 2.5 million/μl or above. The result was satisfactory.View full abstractDownload PDF (3632K) -
Norihiko TAKADA, Hisamichi GOHKE, Hideki SEKIYA, Eisaku IMAMURA1995 Volume 44 Issue 4 Pages 662-667
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThis report presents the epidemiological status of oral mucosal abnomalities and precancerous lesions in a selected population of 6.085 Japanese people (1, 822 women and 4, 663 men, 32-78 years old) from August 1990 to Feburary 1993.
1. Out of 77 cases on which biopsy had been performed, one case (0.02 %) was found to have carcinoma in situ, 37 cases (0.61 %) with leukoplakia, seven (0.12 %) with lichen planus, and 32 cases with other diseases.
2. For the patients with leukoplakia, the screening findings were as follows:
1) The clinical classification of incidences consisted of the simple type (67.6 %), verrucous type (18.9 %), and the nodular type (13.5 %).
2) The most common site of leukoplakia was gingiva (62.2 %), followed by the cheek (21.6 %) and the tongue (13.5 %).
3) Histological findings show that epithelial dysplasia was found in 21 cases (56.7 %) and was graded as mild, moderate, or severe.
4) The number of smokers was 2, 223, and nonsmokers was 3, 862. In the case of leukoplakia, the total of 26 patients were smokers and the rest were nonsmokers. Smoking brings about a statistically significant increase in the incidence of leukoplakia (P <0.001)
5) The number of denture-using examineers was 1, 438, and that of nondenture-using examineers was 4, 647. As for patients with leukoplakia, the number of denture-using examineers was 14 and that of nondenture-using examineers was 24. The difference between groups was not statistically significant.View full abstractDownload PDF (762K) -
Hiroaki KAYAHARA, Chizuru ITO, Hiroyuki HAMAKAWA, Hiroaki TANIOKA1995 Volume 44 Issue 4 Pages 668-673
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSCleidocranial dysplasia is a congenital anomaly that is clinically characterized by complete defect or hypoplasia of the clavicle and abnormal ossification of the skull. In the maxillofacial region, it has various abnormalities such as reversed occlusion with hypoplastic midface, persistence of deciduous teeth with delayed eruption of permanent teeth, supernumerary teeth and malalignment. Recently, a case of cleidocranial dysplasia in a 20-year-old female visited our clinic. Since 13 years-old, her remaining deciduous teeth and seven supernumerary teeth have been extracted, and she has undergone fenestraction of five permanent teeth, frontal traction and lateral expansion of the maxlilla in orthodontic therapy. After the preoperative orthodontic treatment, Le Fort I osteotomy for the hypogrowth of the maxilla was performed to advance it anteriorly. Her midface appearance and the occlusion were remarkably improved after the operation.View full abstractDownload PDF (10566K) -
Satoshi ASANO, Nobuo YOSHIZAWA1995 Volume 44 Issue 4 Pages 674-683
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSPostoperative maxillary cyst (POMC) has been studied extensively while little attention has been given to long-term follow up and healing evaluation.
Paying attention to this situation, the present study was conducted on 26 patients (31 sites) operated on more than 5 years ago for postoperative evaluation based on radiographic data including computed to-mography (CT). The postoperative course was assessed based on clinical scores.
Fiberscopic observation of the nasoantral window was made and the results were compared with CT findings.
The results of this study are as follows.
1. The postoperative maxillary sinus was of 4 types based on CT findings. There were 4 bony fill sinuses (type I), 10 air-containing residual cavities (type II), 13 soft tissue maxillary sinuses (type III), and 4 recurrent cases of cyst formation (type IV).
2. In 9 type III patients, the nasoantral window remained open (type III-1), but was closed in 4 patients (type III-2).
3. The nasoantral window was judged open or closed based on CT findings ; in 7 cases, this was not possible by nasopharyngeal fiberscopic observation.
4. Clinical scores based on 10 items (3 subjective symptoms and 7 objective symptoms) was very useful for making postoperative evaluation, because recurrent cases could be distinguished from the other types.
5. The bony fill maxillary sinus required more than 8 years to form.View full abstractDownload PDF (10981K) -
Etsuaki TASHIRO, Kenji HASHIMOTO, Yasuhiro NAKAMURA, Yoshimasa KITAGAW ...1995 Volume 44 Issue 4 Pages 684-687
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSInterteeth Bracket, a new type of direct bonding bracket, was devised for the fixation of subluxated, luxated and mobile teeth. The purposes of the present study were to introduce this fixation system and evaluate the clinical data.
Teeth fixation with Interteeth Bracket and 4-META adhesive resin was applied to 40 patients (28 males and 12 females). Thirty-five cases (87.5 %) with trauma were included. Twenty-six of 40 patients were able to be reexamined 4 weeks after teeth fixation. There were 6 patients whose brackets had been detached, including 2 cases with deciduous teeth, a case with multiple luxated teeth, acase with acute periodontal infection and 2 unknown cases.
The advantages of Interteeth Bracket are as follows:
1. Even in the case of limited opening of the mouth, this technique is available.
2. This bracket can be easily applied to and removed from teeth with little discomfort.
3. This bracket is matching in color with natural teeth.
The disadvantages are as follows.
The disadvantages are as follows:
1. Interteeth Bracket tends to be detached in cases of deciduous tooth and multiple luxated teeth.
2. There were some patients who did not revisit for removal of the brackets, because patients probably felt little discomfort while wearing the applicance.
It was concluded that Interteeth Bracket was valuable, esthetic and convenient dental material for teeth fixation.View full abstractDownload PDF (3494K) -
Hisao SHIGEMATSU, Munehisa OKADA, Seiji SUZUKI, Tsutomu OSUGA, Fumio K ...1995 Volume 44 Issue 4 Pages 688-692
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSBasal cell nevus syndrome (BCNS) is a complex disease characterized by multiple cysts of the jaws, multiple basal cell tumors of the skin, a high incidence of skeletal abnormalities, and neurological disorders. In this paper, 2 cases of BCNS are reported and the results of clinical investigation of them are discussed.
The first case was a 16-year-old boy who visited our clinic in 1985 with the chief complaint of swelling in the molar region of the left mandible. Clinically, multiple cysts of the jaws, a broad nasal root, malocclusion, mild mandibular prognathism, and palmar pits were observed. Jaw cysts were enucleated. In 1988, occurrences of multiple basal cell nevi of the skin were confirmed. Furthermore, in 1993, recurrence of odontogenic keratocysts in the right mandible and maxilla were confirmed.
The other case was a 6-year-old girl who was referred to our clinic in 1991 because of swelling of the right face with infection. Radiographic examination showed multiple jaw cysts. In addition, general examination revealed frontal bossing, a broad nasal root, ocular hypertelorism, and plantar pits. She had a positive family history. Jaw cysts were enucleated, and she had no recurrence. However, odontogenic keratocysts in the left maxilla and in the left mandible were confirmed about 1 year after surgery on the right jaw cysts ; and in 1993, glioma of the brain was confirmed.View full abstractDownload PDF (5387K) -
Evaluation by Using PeriotoronKazuhide SEKO, Toshio SIGETOMI, Hideaki KAGAMI, Hideki MIZUTANI, Minor ...1995 Volume 44 Issue 4 Pages 693-697
Published: October 10, 1995
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSWhen there is a reduction of salivary flow, it is appropriate to measure the flow rate of whole saliva. However, the flow rate of whole saliva occasionally has conflicted with a dry mouth feeling. The reason for conflict finding is considered to be that the flow rate of whole saliva can not be evaluated without examining the secretory function of minor salivary gland.
The purpose of this study is to evaluate the secretory function of minor salivary gland which correlates with the flow rate of whole saliva and pathological findings of the minor salivary gland in the lip and palate. The examined subjects were 20 female patients with oral dryness. The measurement of unstimulated whole saliva and lip biopsy were carried out on all patients, and the unstimulated salivary flow rate was under 1.0ml/10min. The secretory function of minor salivary gland was evaluated with Periotoron®.
Results suggested that the secretory function of minor salivary gland using periotoron® correlated with pathological findings of lip biopsy.View full abstractDownload PDF (574K)
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