巻号一覧
45 巻 (1996)
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45 巻, 4 号
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特に自律神経の分布とその由来について大須賀 敏1996 年 45 巻 4 号 p. 399-415
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーThe purpose of this study was to determine the origin and describe the location of the autonomic nerve fibers in the temporomandibular joint (TMJ) region of the rat by means of histochemistry and ganglionectomy.
The cells of origin of the autonomic innervation were studied by using wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) by the retrograde axonal transport method. The tracer was injected into the upper joint cavity of the TMJ unilaterally in adult rats. Labelled cells were observed ipsilaterally in the superior cervical ganglion (SCG), otic ganglion (OTG), and pterygopalatine ganglion (PPG); none were found contralaterally.
The glyoxylic acid method, which is the most sensitive amine fluorescence method, was used to identify the sympathetic nerve fibers, and enzyme histochemistry of acetylcholinesterase (AChE) was used to obtain indirect evidence of cholinergic nerve fibers.
Catecholamine fluorescence, which was completely lost on removal of the SCG, was detected along the blood vessels in the pericapsular connective tissue. The amine fluorescence was also seen in the articular disc, which started from the pericapsular fibrous tissue and reached the inmediate lower part of the synovial membrane, and the fluorescence was mainly shown in the upper anterior synovial recess. However, the center of the articular disc was devoid of fluorescence.
AChE-positive fibers, which were almost completely lost on removal of the OTG, slightly lost on removal of the PPG, and completely lost on removal of both ganglions, were observed eccentrically in the auriculotemporal nerve, throughout the masseter nerve, and along the blood vessels. AChE-positive fibers densely innervated the variously sized blood vessels in the pericapsular connective tissue, but were found in neither anterior and posterior bands of the articular disc nor in the center.
These results suggested that most of the sympathetic and parasympathetic nerve fibers are originated from SCG and OTG, respectively. Furthermore, it indicated that nerve fibers from PPG may also exist in the anterior upper portion of the TMJ. It is considered that both sympathetic and parasympathetic nerve fibers run along the internal carotid artery and innervate the TMJ.抄録全体を表示PDF形式でダウンロード (24864K) -
湯浅 秀道, 栗田 賢一, 永坂 佳規, 外山 正彦, 塩島 勝, 有地 榮一郎, 河合 幹1996 年 45 巻 4 号 p. 416-422
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーThe relation between maximal interincisal distance and body height was investigated in children and adolescents aged 9, 12, and 15 for 3 consecutive years. They were students in Okazaki City, Aichi Prefecture. The number of subjects was 249 males and 265 females aged 9 years, 317 males and 258 females aged 12 years, and 135 males and 177 females aged 15 years. The results were as follows:
1) The maximal interincisal distance was statistically significant in age and sex. (male: 9 years-48.4mm, 10years-49.5 mm, 11 years-50.6 mm, 12 years-51.5 mm, 13 years-52.0 mm, 14 years-53.6mm, 15 years-53.4 mm, 16 years-53.0 mm, and 17 years-55.2 mm; female: 9 years-46.4 mm, 10 years-46.4 mm, 11 years-48.1 mm, 12 years-48.8 mm, 13 years-47.4 mm, 14 years-48.8 mm, 15 years-47.6 mm, 16 years-47.1 mm, and 17 years-47.9 mm)
2) Longitudinal changing pattern of maximal interincisal distance showed significant difference between male and female.
3) Maximal interincisal distance and body height increased with age in male.抄録全体を表示PDF形式でダウンロード (695K) -
廣木 朗子, 篠原 正徳, 中村 誠司, 大山 順子, 毛利 武文, 佐々木 匡理, 白砂 兼光1996 年 45 巻 4 号 p. 423-431
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーThe major histocompatibility complex (MHC) class II antigens are well known to play an important role in antigen recognition by T cells and to influence the susceptibility to autoimmune diseases, including Sjögren's syndrome (SS). In this paper, an aberrant expression of HLA-DR antigen was examined immunohistochemically on acinar and ductal epithelial cells of labial salivary glands from 114 SS patients. Aberrant expression of HLA-DR antigens was frequently observed on acinar and ductal epithelial cells and differed markedly in different components of salivary gland tissue. Most acinar and intercalated ductal cells expressed HLA-DR antigen, while fewer intraloberlar ductal cells expressed the antigen. In contrast, most of the interloburlar ductal cells did not express HLA-DR antigen. The expression of HLA-DR antigen was closely associated with lymphocytic infiltration. The more extensive lymphocytic infiltration became, the more HLA-DR positive cells was observed. In some cases, the expression of HLA-DR antigens was observed not only in the areas with lymphocytic infiltration but also in areas where no infiltrating lymphocyte was observed.
Aberrantly expressed HLA-DR antigen enables acinar and ductal epithelial cells to play an antigenpresenting cell role for T cells, and thus might play an important role in precipitating an autoimmune response in SS.抄録全体を表示PDF形式でダウンロード (13772K) -
地挽 雅人, 下田 信治, 川崎 堅三, 豊田 長隆, 荒井 智彦, 佐々木 文彦, 浅田 洸一, 石橋 克禮1996 年 45 巻 4 号 p. 432-437
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーSince it is not well known how the symptoms of TMD are related to the fibrous adhesions in inferior articular cavities of temporomandibular joints (TMJ), fibrous adhesions were studied macroscopically and histologically. Fifty-four TMJs were obtained from 40 cadavers, 15 males, and 25 females aged 58-98 years. The inferior articular cavities were dissected carefully and the correlation between fibrous adhesions and the condition of condyle morphology, as classified by Yale, was studied.
Three types of fibrous adhesions observed in the inferior articular cavities were as follows:(a) fibrous band type, (b) pseudowall type, (c) fibrosis type.
The frequency of adhesions was not related to age. The fibrosis type was frequently seen especially in the posterio-lateral portion of condyles, though pseudowall and fibrous bands were rarely seen in inferior articular cavities. The fibrous adhesions were comparatively frequent in cases of flat type condyles and in cases that had lost the bite in bilateral molar regions. In all four cases with perforation of discs, adhesions were observed in several places around the lesion.
Histological examinations were performed, and the tissues of adhesions consisted of acellular fibrous connective tissues that seemed to be fragile.抄録全体を表示PDF形式でダウンロード (8813K) -
歯科技工士と他職種との比較西川 哲成, 大森 佐与子, 和唐 雅博, 田中 昭男1996 年 45 巻 4 号 p. 438-441
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーPeople who work as welders or in stainless steel production factories are known to be at high risk of lung cancer due to inhalation of airborne chromium which deposits in their lungs. In the present study, the risk of lung cancer in dental staff was assessed by measuring the amounts of various metals deposited in the lung tissue of a dental technician.
At the autopsy of a dental technician who died of cerebral metastasis of lung cancer, pulmonary, hepatic, and renal tissue samples were excised. The amounts of various metals deposited in these organs were determined by thermal neutron radioactive analysis. For two other patients who died of lung cancer, including a welder, and three patients who died of heart disease, various metals were quantitated in the same manner as mentioned above, and the results were compared with those of the dental technician.
The dental technician's lung tissue had a higher content of the metals Au, Ag, Co, Cr, and Cu in comparison with the other patients. The pulmonary deposits of Au, Co, and Cr in particular were higher in this patient than in the welder. These metals, which are present in dental alloys in considerable quantities, were found in the technician's lung tissue almost 10 years after his retirement from the job.
Au and Cr are considered to be allergenic, and Cr is also carcinogenic. The higher levels of pulmonary deposition of these metals in the dental worker, in comparison with other patients and the welder, suggest potential adverse pulmonary effects of these metals.抄録全体を表示PDF形式でダウンロード (447K) -
野口 忠秀, 神部 芳則, 古谷野 浩美, 赤坂 庸子, 矢尾板 英夫1996 年 45 巻 4 号 p. 442-447
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーIn order to clarify the molecular mechanism of cell adhesion between oral keratinocytes, expression pattern of adhesion molecules in human normal gingival epithelia and cultured gingival keratinocytes was analized. The expression pattern was examined immunohistochemically by using monoclonal antibodies for human integrins α2, α3, α5, α6, β1, β4, E-cadherin, P-cadherin, desmoglein, ICAM-1, and VCAM-1. The expression of integrins α2, α3, and β1 was observed as a linear pattern corresponding with the cell membrane in the basal and the spinous cell layers, and that of a6 and β4 was observed on basal cell surface of the basal cell layer.
E-cadherin and desmoglein was observed on the cell membrane of the basal cell layer and the spinous cell layer, while that of P-cadherin in the basal cell layer only. Integrins α2, α3, β1, and Ecadherin were also observed on cell membranes in cultured gingival keratinocytes. After treatment with cytochalasin-B, microfilaments were disrupted and the linear expression pattern of integrins α2, α3 and β1 was drastically changed to a dotted pattern. However, there were no such drastic changes in the expression pattern of E-cadherin even after treatment with cytochalasin-B.
These results demonstrated that integrins α2, α3, β1, and E-cadherin are expressed in cultured human gingival keratinocytes, and suggested that distribution of integrins is restricted by microfilaments but that of E-cadherin may not be restricted strongly by these filaments.抄録全体を表示PDF形式でダウンロード (6481K) -
鹿嶋 光司, 芝 良祐, 迫田 隅男1996 年 45 巻 4 号 p. 448-454
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーData of turns (changes of direction) and mean amplitude, collected by a quantitative electromyographic investigation of the right masseter muscle using surface electrodes, are presented. Such data have rarely been published before and constitute an important basis for future evaluation of masticatory muscle disturbances in temporomandibular disorders. Root mean square (RMS) values of the electrical activity were measured at various isometric contractions in 7 nonsymptomatic subjects. Turns and mean amplitude were calculated, mean frequency was also calculated, and these parameters were plotted for the RMS values. As a result, the number of turns increased gradually as the RMS values increased. However, as voluntary clenching force approached maximum, the increasing rate of turns dropped gradually. On the other hand, mean amplitude values increased proportionally to the RMS values, and their relationship was shown as y=ax+b (a=1.74 ± 0.05, b=88.53 ± 4.39), here “ y ” indicates mean amplitude values, and “ x ” indicates the RMS values, respectively. Frequency for the RMS values did not show a certain tendency.
In conclusion, it is considered that turns reflect firing rates of a motor unit, and mean amplitude values also reflect the size of the motor unit. Therefore, generation of force in the masseter muscle may be more dependent on recruitment of larger motor units than on increase of firing rate at high isometric contraction levels. The use of frequency is not appropriate for evaluation of muscle contraction levels.抄録全体を表示PDF形式でダウンロード (959K) -
小笠原 利行, 石井 保雄, 山本 祥子, 横浜 恵子, 山田 哲史, 林 解平, 北川 善政1996 年 45 巻 4 号 p. 455-461
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーThe purpose of this study was to investigate the initial change of EMG power spectral analysis of jaw closing muscle during maximum clenching in 5 patients with mandibular prognathism (P group: 5 males) and in 5 normal subjects (C group: 5 males). A change of EMG power spectral in the anterior temporal and masseter muscles by momentary maximum clenching in intercuspal position were analyzed for the initial 190 msec which is divided into 5 sections (1 section =38 msec).
The results were as follows:
1. An increasing ratio of the integration of EMG activity in the P group were significantly lower than in the C group, especially in the masseter muscle.
2. In the C group, the MPF (Median Power Frequency) of temporal and masseter muscle shifted lower from section 1 to 2 and such lower shifting became stable in section 5.
3. Temporal and masseter muscle EMG of the P group showed a wider spectrum than those of the C group. MPF was significantly higher in the P group than in the C group, and a change of MPF such as shifting to higher and lower was unstable in the P group.
A change of EMG power spectral analysis during initial maximum clenching was very useful to evaluate the stomatognathic function in mandibular prognathism.抄録全体を表示PDF形式でダウンロード (751K) -
五十嵐 千浪, 小林 馨, 今中 正浩, 山本 昭, 亀井 和利, 近藤 寿郎, 瀬戸 皖一, 石橋 克禮1996 年 45 巻 4 号 p. 462-469
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーEight cases of synovial chondromatosis of the temporomandibular joint were histopathologicaly diagnosed from 1989 to 1994. In our series, panoramic radiography (all cases), computed tomography (five cases), sagittal tomography, arthrotomography, and Magnetic Resonance Imaging (seven cases) were performed.
The image findings were as follows:
Panoramic radiography showed loose bodies in four of all cases.
Computed tomography showed loose bodies in three of five cases.
Sagittal tomography showed loose bodies and osseous change of condyle and temporal compartments in four of seven cases.
Arthrotomography showed loose bodies in the joint compartment of which outline was irregular in all seven cases.
Magnetic resonance imaging revealed marked expansion of the temporomandibular joint cavity of which area of low signal on T1-weighted images and high signal on T2-weighted in all seven cases.
Sixty-eight cases of synovial chondromatosis of the TMJ in the literature and our cases were reviewed. MR imaging proved to be the most useful method to establish a definitive diagnosis of synovial chondromatosis of the temporomandibular joint.抄録全体を表示PDF形式でダウンロード (8099K) -
Implant植立のための顎裂部骨架橋の評価高橋 哲, 福田 雅幸, 幸地 省子, 山口 泰, 永井 宏和, 高野 裕史, 松井 桂子, 越後 成志1996 年 45 巻 4 号 p. 470-478
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーSince 1993, osseointegrated implants have been applied to grafted region with autogenous particulate marrow and cancellous bone to the alveolar cleft at our clinic. In this study, the shortterm clinical outcome at one year and a half after the fixture insertion was evaluated. Furthermore, the grafted bone bridge, to which osseointegrated implants were applied, was retrospectively assessed. Using computer tomography and periapical radiographs, the optimal condition required for the placement of osseointegrated implants to the grafted alveoli was investigated. The results were as follows:
1. Sixteen implants were inserted into 15 grafted alveoli of 15 cleft lip and/or palate patients. All of the implants were osseointegrated and clinically uneventful.
2. The mean available vertical width of the bone bridge was 14.1mm. In 14 of 15 cases, over 13mm-long fixtures could be placed.
3. In 11 of 15 cases (73.3%), the bone quality was estimated as class 2 or class 3 by Lekholm and Zahb's classification, which was durable for the placement of osseointegrated implants.
4. In 7 of 15 cases, the interdental alveolar bone height was insufficient, which was evaluated as score 2. In 4 of 7 cases, chin bone onlay grafting was utilized simultaneously with fixture insertion. Consequently, the interdental bone height was increased.
In conclusion, the bone bridge, after autogenous particulate marrow and cancellous bone grafting, was suitable and durable for the placement of osseointegrated implants. However sometirr es, cases, in which the interdental alveolar bone height is not good enough for the application of osseointegrated implants are seen. Further clinical studies are needed to determine the optimal timing of the secondary bone grafting and the placement of osseointegrated implants.抄録全体を表示PDF形式でダウンロード (8006K) -
岡田 康男, 加藤 譲治, 片桐 正隆1996 年 45 巻 4 号 p. 479-485
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーSixteen autopsy cases of oral and maxillofacial squamous cell carcinoma were examined by the Nippon Dental University, School of Dentistry at Niigata, Department of Oral and Maxillofacial Surgery II from 1974 to 1992. The histological malignancy of initial biopsy specimens in the pretreatment period was evaluated by using the Anneroth classification (1987) and the relationship of the degree of histological malignancy with the distant organic metastases was examined. The following conclusions were reached. Autopsy was performed in 30 of 79 cases (38.0%). Sixteen squamous cell carcinomas were included in this study. Eleven (68.8 %) of these cases had distant metastasis. The most frequent distant metastasis site was the lung. The average of the Anneroth total scores of 16 squamous cell carcinomas was 15.8±2.2. Eight cases with a score of over 3 points for nuclear polymorphism, 3 cases with a score of 4 points for the number of mitoses, and 4 cases with a score of 4 points for the pattern of invasion had distant metastasis.抄録全体を表示PDF形式でダウンロード (813K) -
安原 豊人, 吉田 博昭, 横江 義彦, 藤田 茂之, 村上 賢一郎, 飯塚 忠彦1996 年 45 巻 4 号 p. 486-490
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーA case of metastatic adenocarcinoma of the mandible that originated from the prostate is reported. A 87-year-old male was referred to our hospital due to a complaint of swelling in the left mandible. Medical history revealed prostatic carcinoma. Histopathological biopsy showed that the mass contained adenocarcinoma morphologically similar to that of the prostate. Immunohistochemical staining was performed, and the tumor was stained positively by PSA (prostatic specific antigen) and PAP (prostatic acid phoshatase).
From these results, the mandibular metastatic tumor of prostatic carcinoma was diagnosed. In addition 12 cases of metastatic tumors in the mouth and jaws were consecutively examined in our clinic in the last 15 years. Histologically, they were all squamous cell carcinoma except two cases.抄録全体を表示PDF形式でダウンロード (7854K) -
富井 信之, 高居 欣治, 大内 岳彦, 長谷川 明, 鈴木 智子, 菅野 寿, 川寄 建治1996 年 45 巻 4 号 p. 491-496
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーThe purpose of this study was to evaluate the clinical effects of a new, l-tricalcium phosphate (β-TCP) grafting material on osseous defects in jaws.
Sixty-seven patients were treated by grafting with β-TCP which was blockshaped (1 cm3)
From among them, 4 patients could not be followed up. The followed up cases included 47 radicular cysts, 8 follicular cysts, 3 odontomas, 3 residual radicular cysts, 1 globulomaxillary cyst, and 1 periodontal cyst.
The results were classified according to criteria for evaluating efficacy: Very effective, Effective, Not effective, and Harmful.
Forty cases (63.5 %) were classified Very effective or Effective.
The largest defect was the radicular cyst which was grafted by the 4 blocks. This case was classified Very effective.
In all cases, a side effect due to the grafting material did not occur.
These results suggested that the jS-TCP block is a useful grafting material because of its potential for osseous repair, if the cases are as follows:
1. In infective cases, the source of infection must be removed, completely.
2. The osseous defect is no or small bony perforation.
3. The size of osseous defect is smaller than 4 cm3.抄録全体を表示PDF形式でダウンロード (6278K) -
田中 潤一, 伊藤 亜希, 中根 研, 林 尚徳, 木住野 義信, 松崎 英雄, 高野 伸夫, 高橋 庄二郎1996 年 45 巻 4 号 p. 497-503
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーIn 54 patients with rheumatoid arthriris (RA), radiographic findings of condyle were classified into 5 types (Type I-Type V) and were investigated in relation to RA-stage, interval of RA, temporomandibular joint (TMJ) pain and complications.
Onsets of RA at TMJs were late and mild as compared with other joints. Since many cases of TMJ pain were recognized in Type II, it is conjecturable that these cases included onset of RA in TMJs. Anterior open bite appeared from Type III in cases of bilateral molar supports, but from Type IV in cases of nonsupport; therefore, the frequency of anterior open bite was different in these two groups.
Conservative treatments by intermaxillary traction and adapting activator type occlusal appliance were selected in cases of anterior open bite and obstructive sleep apnea syndrome. It is considered that these treatments were one kind of rehabilitation for muscle function to maintain an adequate mandible position and to compensate resorption of condyle and disappearing external pterygoid muscle function.抄録全体を表示PDF形式でダウンロード (7630K) -
免疫組織化学的および電顕的観察栢原 浩彰, 馬渕 一郎, 浜川 裕之, 谷岡 博昭1996 年 45 巻 4 号 p. 504-508
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーEosinophilic granuloma is an idiopathic benign osteolytic disease characterized by proliferation and infiltration with histiocytic cells and eosinophils. Lichtenstein concluded that eosinophilic granuloma, Hand-Schiiller-Christian disease, and Letterer-Siwe disease were essentially based on the same pathogenesis and grouped these three lesions within the category of histiocytosis X. The concept of histiocytosis X is generally accepted, but several authors have criticized the grouping because the pathogenesis has not been completely resolved yet.
Recently, a case of eosinophilic granuloma arising multifocally in the bilateral mandible was examined at our clinic. Biopsy was performed, and the lesions were found to be composed of histiocytic cells and eosinophils. In the immunohistochemical study, histiocytic cells reacted positively with anti-S-100 protein antibody. Electron microscopy revealed a convoluted segmented nucleus and several long and narrow cytoplasmic processes in the histiocytic cells, including scattered rod-like Birbeck granules.
The histiocytic cells were thought to be Langerhans cells characterized by the presence of Birbeck granules. It was suggested that eosinophilic granuloma occurred with abnormal proliferation and infiltration of Langerhans cells.
The bilateral lesions were curetted under gentral anesthesia, and there has been no evidence of local recurrence for seventeen months since surgery.抄録全体を表示PDF形式でダウンロード (10948K) -
木村 幸紀, 花澤 智美, 岡野 友宏, 道脇 幸博, 道 健一, 南雲 正男1996 年 45 巻 4 号 p. 509-514
発行日: 1996/10/10
公開日: 2011/09/07
ジャーナル フリーTwo cases of the tumor-like necrotic lesions were shown on CT after the combined chemo-and radio-therapy for squamous cell carcinoma in the lower gingiva. The tumor-like mass lesions with the low density areas were found on CT in the parotid and the parapharyngeal space respectively after retrograde intra-arterial chemotherapy via the superficial temporal artery. Histological examination using the specimen obtained by fine-needle aspiration biopsy and extirpation specimens revealed necrosis. Necrosis of the artery peripheral to the catheter-tip might have induced the extravasation of the antineoplastic agent to the surrounding tissues. Although such complications are not often encountered, the lesion should be carefully differentiated from a tumor on CT imaging.抄録全体を表示PDF形式でダウンロード (9994K)
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