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Volume 51, Issue 6
Displaying 1-4 of 4 articles from this issue
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Wei Xiang LIU, Yoshiro MATSUI, Kei TAKAESU, Yuji SHIONOYA, Kohsuke OHN ...2002 Volume 51 Issue 6 Pages 359-365
Published: November 10, 2002
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThis study experimentally investigated the influences of implant therapy on the mandibular growth of young dogs, to obtain clinical suggestions for the treatment of adolescents.
Seven beagles, 12 weeks old and weighing approximately 3 kg, were used. Two weeks after extraction of the deciduous teeth (p1 and 2) and germs of permanent teeth (P1, 2, and 3) of the left mandible, two plasma-sprayed titanium cylindrical implants were placed into the region. One month after the implantation, three animals were given a fixed-type bridge as a superstructure (Connecting-Group). Three among the remaining animals were given two unconnected superstructures for each implant (Non-Connecting-Group). The last animal, which was randomly selected and had undergone only extraction and sham-operation, was served as a control for histological evaluation.
The animals were acrificed six months after the placement of the superstructures. Bone growth was evaluated morphometrically by measuring the distances between anatomical markers of each side of the mandible, respectively, and calculating suppression rates with the data. Bone reaction around implants was observed photomicroscopically with undecalcified sections. Bone formation and remodeling were also evaluated with a labeling technique.
The results obtained were as follows:
1) Implant placement suppressed bone growth around implants.
2) A connected superstructure suppressed bone growth more severely than a unconnected one.
3) Implant did not move with the bone growth by drift.
Implant therapy should be avoided in young patients who have other available options.View full abstractDownload PDF (3072K) -
Kazunari SAKURAI, Junko KURODA, Susumu HASHITANI, Norihiko NISHIMURA, ...2002 Volume 51 Issue 6 Pages 366-373
Published: November 10, 2002
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe role of cyclooxygenase (COX)-2 in metastasis of oral cancer is unclear. To determine whether COX-2 expression could serve as an indicator of metastasis in oral carcinoma, we examined the immunohistochemical expression of COX-2 protein in 30 pairs of primary and metastatic lesions in patients with oral squamous cell carcinoma (OSCC). Consequently, increased expression of COX-2 protein was found in 26 (87%) metastatic lesions of OSCC, as compared to primary lesions. In the localization of COX-2 expression in tumor tissue and cells, diffuse expression was observed in the tumor tissues of metastatic lesions, and tumor cells in them predominantly showed the expression not only in the cytoplasm but also in the nucleus and nuclear membrane. In addition, poorly differentiated OSCC tended to show higher COX-2 expression than well differentiated OSCC, in both primary and metastatic lesions. From these results, it was suggested that expression of COX-2 protein was closely related to metastasis formation in OSCC.View full abstractDownload PDF (3066K) -
Koichiro IHARA, Shigeo JINNOUCHI, Masahito SHTGEMATSU, Masaaki GOTO2002 Volume 51 Issue 6 Pages 374-381
Published: November 10, 2002
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSThe purpose of this study was i) to evaluate postoperative masticatory function in patients that underwent partial mandibulectomy followed by rehabilitation with dental implant-supported prosthodontic treatment, and ii) to determine the efficiency of the implant treatment in those patients.
Masticatory function was investigated in 18 patients who had part of their mandible excised in treatment for oral and maxillofacial disease in our department from 1989 to April 2001. The patients were classified into two groups: 11 malignant tumor cases and 7 non-malignant tumor cases. Controls were 18 volunteers with natural dentition and normal oral and maxillofacial function.
Masticatory function was assessed by a masticatory efficiency test and a questionnaire about the subject's dietary intake, developed by Hirai et al. No significant difference was identified in mastica-tory efficiency after wearing an implant denture between the non-malignant tumor group and the control group, but the malignant tumor group was significantly lower than either the non-malignant tumor group or the control group. In dietary intake questionnaires, both the nonmalignant
and malignant tumor groups showed higher masticatory scores after wearing an implant denture than before use of an implant denture. However, both groups were significantly lower in masticatory score compared with the control group.
The results indicate that an implant denture was effective in enhancing masticatory function in mandibulectomy patients, but its ability was not so improved as the healthy control group.View full abstractDownload PDF (1769K) -
Aki KITAJIMA, Katsuhiro ONIZAWA, Seiji ASODA, Souichirou ASANAMI2002 Volume 51 Issue 6 Pages 382-386
Published: November 10, 2002
Released on J-STAGE: September 07, 2011
JOURNAL FREE ACCESSvon Recklinghausen's disease is a syndrome defined by the presence of caf-au-lait spots and multiple benign neurofibroma. Oral involvement is relatively rare in von Recklinghausen's neurofibromatosis.
A case of von Recklinghausen's disease with an intra oral and lower lingal gingiva lesion is reported.
A 11-year-old boy was referred to our department with swelling of the mid of lower lingal gingiva. His mother, sister, and grandfather had von Recklinghau- sen's disease. The patient had many cafe-au-lait spots extending all over the body, and a mass in the lower gingiva, which was 25 X 10 mm in size. Extirpation of the tumor was carried out under general anesthesia. The histopathological diagnosis was a neurofibroma. The patient's postoperative course was uneventful.View full abstractDownload PDF (2525K)
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