日本口腔科学会雑誌
Online ISSN : 2185-0461
Print ISSN : 0029-0297
ISSN-L : 0029-0297
52 巻, 5 号
選択された号の論文の6件中1~6を表示しています
  • 笠原 和恵, 鄭 漢忠, 上野 尚雄, 泉山 ゆり, 前川 邦昭, 戸塚 靖則, 井上 農夫男
    2003 年 52 巻 5 号 p. 219-226
    発行日: 2003/09/10
    公開日: 2011/01/31
    ジャーナル フリー
    The aim of this study is to clarify the relationship among ingestion and swallowing disorder, life satis faction, and social activity of the independent-living elderly aged 65-85 with a high level of physical activity. Questions regarding social activity (IADL), life satisfaction (modified PGC Morale Scale), eating habits, masticatory ability, and ingestion and swal lowingdisorders were given to the following groups of 71 subjects:(1) 29 males and 26 females (mean age 72.3 years) who usually play volleyball in a public health center club and, (2) 16 males (mean age 75.6 years) who practice kendo (Japanese fencing). Oral examinations, evaluations for occlusal force by using “Dental PrescaleTM”, modified water swallowing test and food test were performed.
    The results were as follows.
    1) The factors indicating statistically significant data with regard to life satisfaction as a dependent variable using stepwise regression were swallowing disorder and masticatory ability.
    2) The factors indicating statistically significant data with regard to social activity as a dependent variable using stepwise regression was ingestion and swallowing disorder.
    3) The results of this study revealed close relation shipsamong ingestion and swallowing disorder, life satisfaction and social activity. Therefore, this study suggests the importance of oral function among the elderly who practice an independent life style.
  • 植田 栄作, 木村 剛, 谷田 豊宏, 岡本 哲郎, 岡本 敦子, 森 仁志, 山本 哲也, 尾崎 登喜雄
    2003 年 52 巻 5 号 p. 227-234
    発行日: 2003/09/10
    公開日: 2011/01/31
    ジャーナル フリー
    We investigated 211 patients with hyposalivation during the last 15 years to examine the cause, oral abnormalities, and effect of a salivation-stimulating drug, anethole trithione. Hyposalivation was caused by physiological (senile) hypofunction of the salivary gland, medical treatment (drug medication and cancer therapy), anemia and mental distress in 123, 72, 8, and 8 patients, respectively. As oral abnormalities, oral dryness, glossal pain, oral abnormal sensation/hyper-irritation (candidiasis), and taste abnormality were observed in 80, 63, 56, and 12 patients, respec tively.Before treatment, both non-stimulated sali varyflow rate (N-SFR) and stimulated SFR (S-SFR) in the patients were significantly lower than in age-matched healthy controls: N-SFR and S-SFR in the controls=4.30±1.45 and 12.45±4.82ml/10min, respectively, whereas N-SFR and S-SFR=0.71±0.49-5.25±4.92ml/10min in senile hypofunction, 1.03±0.65-2.88±1.98ml/10min in cancer therapy-induced, 0.83±0.67-8.75±8.03ml/10min in drug-induced, 0.78±0.70-5.36±4.15 ml/10min in anemia-induced and 0.95±0.81-9.86±2.68ml/10min in mental distress inducedhyposalivation. After administration of ane tholetrithione in 101 patients, N-SFR increased and improved or eliminated oral dryness, glossal pain and candidiasis in all patients. These results conclusively indicate that administration of an appropriate saliva tion-stimulating drug is recommended following accu rateidentification of the cause of hyposalivation.
  • 川上 哲司, 森杉 敏明, 大枝 直之, 藤田 宏人, 吉村 安郎, 桐田 忠昭
    2003 年 52 巻 5 号 p. 235-242
    発行日: 2003/09/10
    公開日: 2011/01/31
    ジャーナル フリー
    It is proposed that synovial inflammation mediated by induced cyclooxygenase-2 (COX-2) plays an impor tantrole in the onset of temporomandibular joint (TMJ) pain. However, we have little knowledge about the pathophysiology of TMJ pain. In this study, the expression of COX-2 in lapine synovial fibroblast cells (HIG-82) following mechanical stretch was investi gated. Western blot analyses indicated that the level of the expression of COX-2 protein in HIG-82 in creasedin response to mechanical stretch (140%). We also observed nuclear translocation of p65 which is one of the nuclear factor-κ B (NF-κ B) family members in response to stretching. To investigate whether the induction of COX-2 was under NF-κ B control, we measured luciferase activity in cells transfected with pNF-κ B-Luc. Compared with the control, mechanical stretch treatment significantly increased the promoter activity of the NF-κ B. These results showed that mechanical stress on synovial membrane induced COX-2 via activation of NF-κ B. The present study suggested that synovial inflammation due to repetitive motion, such as bruxism, might lead to TMJ pain.
  • 柴原 孝彦, 神尾 崇, 浜瀬 真紀, 武田 栄三, 高崎 義人, 野間 弘康
    2003 年 52 巻 5 号 p. 243-246
    発行日: 2003/09/10
    公開日: 2011/01/31
    ジャーナル フリー
    A method of autologous nerve grafting for repair of the inferior alveolar nerve after mandibular resec tionusing a forearm cutaneous nerve is described. The lateral cutaneous nerve of the forearm served as the donor nerve and the graft was inserted microsurgically using an epineurial nerve suture technique in five subjects. Return of sensation in a series of five patients was measured by the Semmes-Weinstein method. Sensitivity of the lower lip and chin was recovered after about ten months in all five subjects. The lateral branch of the forearm cutaneous nerve is a useful graft for repair of the inferior alveolar nerve following mandibular resection in which a forearm flap is used as part of the reconstrurtion.
  • 特に他覚的, 自覚的構音機能の変化について
    寺井 陽彦, 島原 政司
    2003 年 52 巻 5 号 p. 247-252
    発行日: 2003/09/10
    公開日: 2011/01/31
    ジャーナル フリー
    This study evaluated objective and subjective articulatory functions after secondary operation using artificial grafts for glossectomized patients with speech disorders, caused by cicatrix of the primary operation. The subjects consisted of 4 males and 3 females who were diagnosed as having a tongue cancer and underwent a glossectomy followed by direct suture without reconstruction. They received a secondary operation to mobilize the residual tongue using an artificial graft. Objective and subjective assessments of articulatory function were performed before, and 6 and 12 months after the secondary operation.
    Objective and subjective articulatory functions significantly improved after the secondary operation. The results suggested the possibility of improving speech disorders in glossectomized patients by the secondary operation using an artificial graft.
  • 飯野 光喜, 福田 雅幸, 永井 宏和, 大貫 敬嘉, 山岡 薫, 戸嶋 慎一
    2003 年 52 巻 5 号 p. 253-260
    発行日: 2003/09/10
    公開日: 2011/01/31
    ジャーナル フリー
    Iliac particulate cancellous bone and marrow (PCBM) grafts combined with titanium mesh have been one of the most common surgical procedures for the repair of large mandibular discontinuity. From the anterior ilium which is the most common donor site, however, harvesting a proper amount of PCBM for a large mandibular defect is sometimes difficult. On the other hand, it is well known that the poste riorilium is an excellent donor source for sufficient volume of PCBM.
    During the past three years, large discontinuity defects of the mandible were reconstructed in 7 patients with PCBM from the bilateral posterior hip combined with titanium mesh. The reconstruction surgeries were carried out immediately in one patient and secondarily in 6 patients. Causes of mandibular defects were malignant tumor in 5 patients, and trauma and osteomyelitis in one patient respectively. Four patients with malignant tumor underwent radiotherapy prior to the mandibular reconstruction.
    During the surgery, a sufficient amount of PCBM was easily and quickly harvested from the bilateral posterior ilium in all cases. There was no serious postoperative complication related to the surgery. Satisfactory mandibular forms were obtained in all 7 patients. Excellent dental rehabilitation was com pletedwith the use of endosseous implants into the reconstructed mandible in 4 patients.
    In conclusion, reconstruction of the large mandibular defects by using titanium mesh and PCBM from bilateral posterior iliac crests is considered to be a highly useful surgical management.
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