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Volume 53, Issue 4
Displaying 1-5 of 5 articles from this issue
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Narikazu UZAWA, Ryozo MIYAMOTO, Kunihiro MYO, Teruo AMAGASA2004 Volume 53 Issue 4 Pages 149-154
Published: September 10, 2004
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSAmplification of cyclin Dl (CCND1) has been frequently found in head and neck squamous cell carcinomas (SCCs) including oral cancer, suggesting that CCND1 amplification may play an important role in the tumorigenesis of oral SCCs and may serve as an independent prognostic indicator. In the present study, to investigate CCND1 amplification in 9 primary tumors (PTs) and matched lymph node metastases (LNMs), fluorescence in situ hybridization (FISH) on fine-needle aspiration biopsies (FNA) were performed. When CCND1 amplification was identified in PTs, this genetic alteration was always determined in the matched LNMs. On the other hand, when cancer cells in PTs did not show CCND1 amplifica tion, no tumor cells in matched LNMs exhibited amplification. From this study, it may be concluded that CCND1 amplification develops in carcinogenesis before lymph node metastases occur and is main tainedduring metastasis.View full abstractDownload PDF (1950K) -
Yasuo KOMORI, Hiroshige CHIBA, Kenichi MATSUDA, Tomoaki INO, Motoshi T ...2004 Volume 53 Issue 4 Pages 155-160
Published: September 10, 2004
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSA number of manifestations of systematic oppor tunisticinfections are found in patients infected with the human immunodeficiency virus (HIV). Further more, there are many symptoms involving the oral cavity. We examined the records of 200 HIV-infected patients who had been treated during the last 15 years in our department. We report the results of a clinical survey of HIV infected patients and the relationship between symptoms and CD4 lymphocyte counts.
Oral candidiasis is the most common oral manifes tationand was found in 93 cases (47%) and xerosto miain 43 cases (22%), recurrent aphthous stomatitis in 32 cases (16%), and oral hairy leukoplakia (OHL) in 23 cases (12%). There were also 10 cases with thrombocytopenic purpura, 9 with Kaposi's sarcoma, 8 with herpes simplex, each 6 with hyperpigmentation and linear gingival erythema, and 5 each with necrotizing ulcerative gingivitis and salivary gland enlargement, and 3 each with ulceration NOS (not otherwise specified), herpes-zoster and neurologic disturbances. Averege CD4 lymphocyte count in 67 asymptomatic cases was 426.4/μl, but in cases with 1 symptom the count decreased to 227.2/μl, then in those with 2 symptoms it was 165.1/μl, in those with 3 symptoms, it fell to 85.6/μl, in those with 4 symptoms to 74.7/μl, while in those with 5 or more symptoms to 15/μl. Thus, the more symptoms they had, the lower the average CD4 lymphocyte count became.View full abstractDownload PDF (826K) -
Especially on the importance of screening tests for the detection of the second primary carcinomasTetsuya YAMAMOTO, Keima KATAYAMA, Eisaku UETA, Takaaki KAMATANI, Yukih ...2004 Volume 53 Issue 4 Pages 161-166
Published: September 10, 2004
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSAmong 485 patients with primary oral carcinoma treated in the Department of Oral Oncology, Kochi Medical School during the past 22 years, 33 patients (6.8%) who revealed second primary carcinoma of other organs were clinically investigated, and the following results were obtained. 1) Among oral carcinomas, tongue carcinomas most frequently accompanied extra oralsecond primary carcinomas (8.8%), followed by gingival carcinomas (6.5%) and other side carcinomas (5.5%). 2) As to the sites of the second primary carcinoma, esophagus, stomach and intestine were most frequently involved (in 12 patients) and the lungs were involved to almost the same degree (in 10 patients). 3) Compared to the occurrence in females (4 of 184 patients, 2.2%), many males revealed double carcinomas (29 of 301 patients, 9.6%). 4) Of the recent 44 patients who underwent gastrointestinal fiberscopy, 5 patients (11.4%) revealed an early carcinoma in the examined organs. 5) The extra-oral carcinomas (the second primary carcinomas) which were detected by gastrointestinal fiberscopy and other screening exami nationsduring treatment of the oral carcinoma and just after (one month) the treatment were almost controlled but the lately detected second primary carcinomas were frequently uncontrolled. These results indicate that in patients with oral carcinoma, extra oralsecond primary carcinoma occurs unexpectedly frequently and that screening examinations for the early detection of the second primary carcinoma is impor tantfor the benefit of oral carcinoma patients.View full abstractDownload PDF (780K) -
Michio SHIKIMORI, Hideo TANAKA, Mutsuhiko MURAI, Hisako KOMATSU, Kenji ...2004 Volume 53 Issue 4 Pages 167-172
Published: September 10, 2004
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSClinical applications of transoral endoscopic sinus surgery (TESS) for odontogenic maxillary sinusitis are reported.
Patients and methods: These procedures were carried out for odontogenic maxillary sinusitis without another sinusitis, confirmed by image diagnosis. Two holes of 5 mm in diameter were made in the frontal wall of the maxillary sinus about 5 mm above the apex of the first premolar for installing the fiberscope and for inserting the instruments. When the infection was found, the inner surface of the sinus was rinsed. After cleaning the sinus, opening of its ostium was confirmed endoscopically. Fifteen procedures were carried out in 14 patients (average age of 44.1 years).
Results: The TESS was performed in 12 cases. Counter ostium opening was used together with TESS in one case and maxillary sinusotomy was used in two cases. The average operating time was 1.49 hours, and the average bleeding during surgery was 57.5 grams. Twelve cases were evaluated on the prognosis for an average of 13.3 months postoperatively, but the 3 cases followed for less than 6 months were excluded. Among the 12 cases followed-up, 8 cases showed no problems in image examination and clini calevaluations 4 cases with clinical problems or with some findings in image examinations were seen, but one case needed additional treatment for abscess.
Discussion: The TESS procedure proposed here simply involves: evaluating the sinus with endoscopy, rinsing it, and confirming the condition of the ostium by non-invasive methods.View full abstractDownload PDF (1416K) -
Erratum to : Hemostatic management of tooth extraction in patients undergoing antithrombotic therapy2004 Volume 53 Issue 4 Pages e1
Published: 2004
Released on J-STAGE: January 31, 2011
JOURNAL FREE ACCESSDownload PDF (21K)
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