巻号一覧
56 巻 (2007)
- 4 号 p. 341-
- 3 号 p. 263-
- 2 号 p. 215-
- 1 号 p. 1-
56 巻, 4 号
選択された号の論文の7件中1～7を表示しています
- |<
- <
- 1
- >
- >|
-
横手 優介, 伊東 博司, 山崎 章2007 年 56 巻 4 号 p. 341-349
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーThis study was undertaken to elucidate the tissue responses to pulsed carbon dioxide laser irradiation with special reference to its tissue ablation property and effect on tissue protection and repair.
Pulsed irradiation was performed on the posterior palatal mucosa and anterior palatal ruga of male Wistar rats, 7-9 weeks of age, with the parameters of 6W, 800μs pulse duration, and pulse repetition rates of 32.47 pps. At 30min, 6, 12, 24, 72 hrs after irradiation, the palatal mucosa was dissected and examined by immunohistochemistry.
In the area irradiated by the pulsed wave, a full thickness of palatal epithelium underwent coagulation necrosis but damages in the subjacent lamina propria were minimal or indiscernible. Re-epithelization took place throughout the wound surface by 24 hrs after irradiation. After 6 to 12 hrs, a strong transient expression of stress protein Hsp70 was observed in the epithelial cells facing the necrotic zone and connective tissue cells in the subjacent lamina propria. The cells expressing anti-macrophage antibody ED1 appeared in the lamina propria adjacent to the necrotic epithelium at 6 and 12 hrs after irradiation, but they were less prominent than in the scalpel incision group. First noted at 6 hrs, an uptake of bromodeoxyuridine, used as a marker for cell proliferation, increased with time and reached a maximum at 24 hrs. The number of labeled cells was significantly larger in the pulsed irradiation group than in the scalpel incision group.
The present results indicate that pulsed irradiation with the parameters in this study is feasible for selective ablation of superficial lesions in oral mucosa and suggest that the irradiation enhances the cell protection system and hence accelerates tissue healing.抄録全体を表示PDF形式でダウンロード (4488K) -
富田 美穂子, 中村 浩二, 福井 克仁2007 年 56 巻 4 号 p. 350-355
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーIt is known that mastication increases cerebral blood flow and neuronal activities in various regions of the human brain. One hundred and eleven subjects (aged 23-84 years) were divided into a control group and two testing groups, and were examined for the effect of 10 minutes of mastication on short-term memory by using two different memory tests (A and B). Subjects were told that each test consisted of 64 pictures to memorize and 64 pictures to recall. However, they were not informed that half of the pictures to recall were the same as the pictures to memorize. First, each subject was asked to memorize 64 pictures presented one by one. Then, for testing the effect of mastication on short-term memory, subjects were asked to identify those they had previously memorized from 64 pictures to recall. When these memory tests were done before (A) and after (B) mastication, the difference between the mean (±SD) test score of A (76.8±10.1) and B (82.2±8.7) was statistically significant (Paired Rest, p<0.05). In the control group without mastication, the mean test scores for A (75.7±8.0) and B (77.7±6.2) were not statisti cally different. These results indicate that mastication significantly improves short-term memory, particularly in subjects older than 60 years old.抄録全体を表示PDF形式でダウンロード (916K) -
矢郷 香, 朝波 惣一郎, 高田 聖子, 酒向 淳, 臼田 慎, 山田 学, 中川 種昭, 田中 陽一2007 年 56 巻 4 号 p. 356-366
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーFifty-six cases of salivary gland tumors histopathologically diagnosed at the Department of Dentistry and Oral Surgery, School of Medicine, Keio University from Janu ary 1998 to December 2005 were reviewed and clinically analyzed. The results were as follows:
1. They were composed of 67.9% benign tumors and 32.1% malignant tumors
2. They were 30 males (53.6%) and 26 females (46.4%), and the male to female ratio was 1. 2: 1.
3. Their mean age was 51.9 years old with a peak incidence in the fifth to sixth decade of life.
4. Swelling was the most common symptom presented. There was pain and ulcer in addition to swelling in malignant tumors.
5. Parotid gland tumors were most common in major salivary glands and palatal gland tumors were most common in minor salivary glands.
6. Pleomorphic adenoma was most common in benign tumors. Of malignant tumors, 8 were adenocystic carcinoma, 5 mucoepidermoid carcinoma, 3 adenocarcinoma, one carcinoma in pleomorphic adenoma and one acinic cell carcinoma.
7. Surgical treatment was performed for all benign tumors and 88.9% of malignant tumors. In malignant tumors radiotherapy and/or chemotherapy were used concomitantly.
8. Recurrence rate of benign tumors was 5.6% and that of malignant tumors was 27.8%. The cumulative survival rate for all malignant cases was 86.5% at 5 years and at 10 years.
9. We report rare cases of carcinoma in pleomorphic adenoma in the palate that developed from benign pleomorphic adenoma and familial pleomorphic adenoma.抄録全体を表示PDF形式でダウンロード (6355K) -
田坂 明子, 浅田 洸一, 臼井 弘幸, 中山 礼子, 山本 英雄, 石橋 克禮2007 年 56 巻 4 号 p. 367-373
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーNormative warm and cold thresholds were assessed at the trigeminal region in 44 healthy volunteers, 24 females and 20 males, aged from 24 to 41 years, using a thermostimulator based on heat flux, which indicates the movement of heat energy. The heat flux thresholds are useful for measuring thermal thresholds of the trigeminal region, characterized by observation of minute thermal changes. Women showed high sensitivity to small tem-perature changes, as reflected by their warm and cold perception threshold. No differences were found in thermal sensitivity between the infra orbital and mental regions of the skin. Sensitivity to cooling was significantly greater than the sensitivity to warming at two branches of the trigeminal nerve.抄録全体を表示PDF形式でダウンロード (1532K) -
南部 弘喜, 又賀 泉, 青木 茂治2007 年 56 巻 4 号 p. 374-384
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーFifty-three Candida albicans strains clinically isolated from 31 patients with oral candidosis were examined for the biochemical characteristics, molecular biological characteristics, and sensitivity to anti-fungal drugs. Biochemical characteristics were examined on production of chlamydospore at hyphal tip, carbohydrate assimilation pattern, extracellular proteinase activity and phospholipase. Molecular biological characteristics were assessed by means of the polymerase chain reaction (PCR) and random amplified polymorphic DNA (RAPD) method. The sensitivity to anti-fungal drugs was analyzed MIC for amphotericin B, flucytosine, fluconazole, itraconazole, and miconazole.
All 53 strains produced chlamydospore on corn meal agar. Carbohydrate assimilation pattern showed many different patterns, and 49 strains of 53 clinically isolated yeasts were identified as Candida albicans. A number of variations were found among proteinase and phospho-lipase production on the plate method. Four of the 53 strains had high proteinase activity and five of the 53 strains showed high phospholipase activity.
RAPD typing methods could reveal differences and detected many different band patterns among the 53 strains of Candida albicans. At the MIC examination for anti-fungal drugs, 17 strains showed high resistance to fluconazole and they showed cross-resistance to itraconazole.
These results indicate that molecular biotyping offers more advantages in terms of simplicity and rapidity than previously established methods and may prove useful for surveying large numbers of pathogens in molecular epidemiological studies.抄録全体を表示PDF形式でダウンロード (2652K) -
二次的インプラント埋入に対する増生骨の骨反応についての実験的研究栗原 淳, 勝部 朝之, 川村 仁2007 年 56 巻 4 号 p. 385-399
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーThe purpose of this study was to establish a vertical alveolar ridge augmentation using a distraction device composed of bioresorbable HA/PLLA composites, and to safely apply dental implants to a distraction area. The distraction device comprised titanium bone screws, HA/PLLA transport plates, and base plates. Six beagle dogs were used for the experiment. Both premolars of the mandible were extracted previously, and the distraction device was placed after 12 weeks. After a latency period of 7 days, the box-forming segment was raised vertically by 7mm at 1.0mm/day by rotating a screw. After distraction, two implants were placed into the left side of the mandible after a retention period of 6 weeks (group A) or into the right side after a retention period of 12 weeks (group B) to penetrate the transport segment and the distraction area. The beagles were killed after 3 months of implantation, and the distraction area, implant surround and HA/PLLA surround were estimated and studied clinically, radiologically and histologically. The bone-implant contact rate (BIC) was measured in both groups. During the experiment, infection and lack of the distraction device were not recognized. The transport segments rose with rotation of the bone screw and we observed that spaces were formed between the transport segment and basal bones. From long-term observation with X-ray, intraosseous spaces showed a gradual increase of impermeability, and bone regeneration was histologically recognized between the intraosseous spaces. The BIC of group B was higher than that of group A. Histologically, foreign-body reaction was not significant around HA/PLLA. These results showed that vertical alveolar distraction was possible by this distraction device. A suitable retention period was important for osseointegration of the implant in the distraction area. It is considered that tissue damage caused by HA/PLLA was extremely small.抄録全体を表示PDF形式でダウンロード (7919K) -
宮内 美和, 吉岡 幸男, 東川 晃一郎, 小泉 浩一, 太田 耕司, 谷 亮治, 林堂 安貴, 虎谷 茂昭, 杉山 勝, 鎌田 伸之, 岡 ...2007 年 56 巻 4 号 p. 400-404
発行日: 2007/09/10
公開日: 2011/01/31
ジャーナル フリーThe novel hydroxyapatite ceramics, NEOBONE®, has a unique porous structure with fully opened interpore connections. This structure has the advantage that host tissues promptly grow into the pores. Clinical usage of NEOBONE® has been reported in the orthopedic field, but not in the oral and maxillofacial field. Granulated powder of NEOBONE® was filled into bone defects in 16 cases consisting of 15 bone cysts and one benign tumor. We followed up all the cases for more than six months. Adverse events were not observed in any of the cases.X-ray findings revealed that the opacity between NEOBONE® and bone increased as a result of bone regeneration. NEOBONE® was shown to be easy to use and harmless for the surrounding tissue. In conclusion, NEOBONE® is a useful bone substitute to fill defects of bone in the oral area.抄録全体を表示PDF形式でダウンロード (2991K)
- |<
- <
- 1
- >
- >|