日本口腔科学会雑誌
Online ISSN : 2185-0461
Print ISSN : 0029-0297
ISSN-L : 0029-0297
60 巻, 3 号
選択された号の論文の9件中1~9を表示しています
原著
  • 佐野 直人, 山下 佳雄, 秋山 兼範, 宮本 比呂志, 後藤 昌昭
    2011 年 60 巻 3 号 p. 219-225
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    More than 700 bacterial species, of which over 50% have not been cultivated, have been detected in the oral cavity. Although research on organisms of caries or periodontosis is progressing, there are very few reports on studies of normal flora in the mouth. Therefore, we identified saliva flora including those that cannot be cultivated, using 16S ribosomal RNA gene which it has only bacteria.
    We used this method to analyze bacterial flora in saliva of patients with periodontal disease, and compared the results with healthy subjects. Consequently, bacterias such as Peptostreptococcus, Veillonella, Clostridium, porphyromonas, Capnocytophaga were detected, which are normally not seen in healthy subjects. This method could help clarify the symptoms of periodontal disease or odontogenic infection.
  • 山下 佳雄, 合島 怜央奈, 檀上 敦, 後藤 昌昭
    2011 年 60 巻 3 号 p. 226-231
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    Of all the bones in the maxillofacial area, the condylar process is one of the most susceptible to fracture. Correct anatomical reconstruction of the condylar process is an important prerequisite for re-establishing function. It is important to ensure that the operator is able to conduct anatomic reduction and rigid internal fixation under direct vision of the completely exposed fractured end. The retromandibular approach was first proposed by Hinds and Girotti in 1967. Compared with the submandibular approach, it is closer to the condylar process and offers better exposure to the fracture site. This report describes the retromandibular approach for reduction and fixation of mandibular condylar fractures. The study group included 6 patients who had undergone surgery for 8 condylar fractures. There was no permanent facial nerve damage, salivary fistula or ankylosis in any of the patients.
    We suggest that the retromandibular approach should be the technique of choice for condylar fracture management, because it seems to be a safe and efficient method for reduction and internal fixation of condylar fractures.
  • 村田 真穂, 梅田 正博, 竹内 純一郎, 鈴木 泰明, 渋谷 恭之, 重田 崇至, 長谷川 巧実, 李 進彰, 小林 正樹, 古森 孝英
    2011 年 60 巻 3 号 p. 232-239
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    Neoveil® is a biodegradable, mesh sheet composed of polyglycolic acid. It has been used for strengthening tissue defects or suturing together with fibrin glue in thoracic surgery and gastroenterological surgery, but its application to oral and maxillofacial surgery has not been reported. We used Neoveil® and Bolheal® for 94 patients (107 sites) who underwent oral and maxillofacial surgery, and the following results were obtained.
    1. Neoveil® and Bolheal® were applied most frequently to the raw surface after resection of mobile mucosa such as the tongue or buccal mucosa, but were also applied to the bone surface after mandibulectomy or maxillectomy, raw surface for alveolar augmentation, rupture of the mucosa of the maxillary sinus during sinus lift, or sites susceptible to bleeding.
    2. Neoveil® remained in the wound for 3-4 weeks in most cases, and was useful for prevention of postoperative bleeding, relief from postoperative pain, and reduction of postoperative scar contracture.
    3. Neoveil® sometimes detached soon from the wound when oral feeding started immediately after the surgery, suggesting that tube feeding is necessary for at least 2 days postoperatively.
  • 福島 洋介, 依田 哲也, 荒木 隆一郎, 中嶋 京一, 堀 直子, 中本 紀道, 佐藤 毅, 坂田 康彰
    2011 年 60 巻 3 号 p. 240-245
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    We examined the effect of 7-day application of the oral moisturizer Aqua Mucus® in patients with dry mouth. In these subjects, the resting salivary secretion, measured by the spitting method, was less than 1.5 ml/15 min or the stimulated salivary secretion, measured by the gum test, was less than 10.0 ml/10 min. We rated resting salivary secretion, stimulated salivary secretion, and extent of oral moisture, measured using an oral moisture checker; and 6 subjective symptoms of dry mouth (dry mouth, eagerness to drink, difficulty in taking food, sensation of saliva, difficulty in pronunciation, and abnormal taste sensation) using the visual analogue scale (VAS) at the start of the experiment, after 7 days of use, and after a 7-day period of non-use. We analyzed the variations with one-way repeated measures analysis of variance, Dunnett's multiple comparison test, Friedman's test, and Dunn's multiple comparison test.
    Results: The mean age of 15 subjects was 65.9 years. The average resting salivary secretion and average stimulated salivary secretion had significantly increased after using the oral moisturizer. The average extent of tongue and buccal mucosa moisture increased significantly from 26.3 ± 4.1 to 29.6 ± 1.7 and from 28.3 ± 2.4 to 30.4 ± 1.5, respectively. With respect to the subjective symptoms of dry mouth, the changes in the median VAS scores changed significantly for dry mouth, difficulty in taking food, sensation of saliva, and difficulty in pronunciation. Thus, we conclude that the oral moisturizer is easy to use and has very few side effects, and should be routinely used as an adjuvant treatment for dry mouth.
  • 森 紀美江, 山下 夕香里, 武井 良子, 綾野 理加, 高橋 浩二
    2011 年 60 巻 3 号 p. 246-253
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    This study was designed to investigate the articulatory movements of lateral articulation. Ultrasonography was used to examine the tongue at rest and tongue movement patterns in patients with lateral articulation and to compare with those of normal subjects.
    The subjects included 17 patients with lateral articulation (LA, 7-37 years old, 8 males and 9 females) and 12 normal speakers (NS, 21-48 years old, 6 males and 6 females). Symmetry of the tongue muscle echo area at rest was examined in coronal section, and tongue shape and movement patterns during vowel production were examined in coronal and sagittal sections. The vowel /i/ which is susceptible to lateral articulation and the vowel /a/ which is not susceptible were examined.
    The results were as follows.
    1. All LA showed an asymmetrical echo area in coronal section, while NS showed a symmetrical echo area. Anatomical asymmetry in the tongue muscle was suggested as one of the causes of lateral articulation.
    2. In coronal section, most subjects in both groups showed a flat or groove shape; a convex shape was seen only in LA. The movements of the tongue edge were asymmetrical in LA but not in NS.
    3. In sagittal section, LA showed different movement patterns from those of NS, suggesting that observation from sagittal section is needed.
    4. Compared to NS, LA showed different tongue movement patterns not only during production of susceptible /i/ but also not susceptible /a/, suggesting the need to investigate tongue movement patterns for other vowels as well.
症例
  • 石井 広太郎, 窪田 泰孝, 松浦 理城, 清水 真弓, 小林 家吉, 白砂 兼光
    2011 年 60 巻 3 号 p. 254-258
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    This report presents a case of adenoid cystic carcinoma (ACC), treated with concurrent combination therapy with 5-Fluorouracil, vitamin A, and radiation (FAR therapy). The case was a 61-year-old male with ACC of the left mandible and lung metastasis (T4N0M1). The tumor extended into the mandibular ramus and the pterygo-mandibular and parotid spaces with severe bone destruction. The patient underwent FAR treatment, resulting in a decrease in size of the primary tumor (56% reduction) and in an increase in formation of bone-like tissue. Successful pain control was acquired. However, the unirradiated metastatic lung lesions continued to progress and a metastatic brain lesion eventually appeared. The patient died 19 months after the initial presentation. This case suggests that FAR treatment is effective for improving the quality of life of patients with inoperable ACC.
  • 小堀 善則, 泉山 ゆり, 鈴木 豊典, 北村 哲也, 進藤 正信, 鄭 漢忠
    2011 年 60 巻 3 号 p. 259-263
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    Lingual osseous choristoma is a rare lesion. We report a case of lingual osseous choristoma on the radix of tongue, with a review of the literature.
    The patient was a 37-year-old female. She had no symptom and accidentally found the lesion herself. The lesion was a hard pedunculated mass measuring about 8 mm. The mass was excised under general anesthesia. Histopathological examination revealed the mass to be composed of dense lamellar bone surrounded by thin fibrous tissue. The pathological diagnosis was osseous choristoma. She remained free of recurrence in the excised area of the tongue for about 19 months.
    We analyzed this case along with 61 similar cases reported in the literature. The most common anatomic location is the posterior third of the tongue close to the foramen caecum.
  • 廣谷 拓章, 千葉 雅俊, 福井 功政, 越後 成志
    2011 年 60 巻 3 号 p. 264-270
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    We report two cases of symptomatic trigeminal neuralgia with intracranial tumor noticed by tooth extraction, which were diagnosed immediately by MRI. Case 1 was a 21-year-old male who had right facial sharp pain after removal of a right wisdom tooth in the mandible. He was suspected to be suffering from symptomatic trigeminal neuralgia because of his young age, no trigger zone, and pain while asleep. MRI revealed that an epidermoid tumor was compressing the right trigeminal nerve at the root entry zone. Near total excision of the tumor was performed and the pain disappeared. Case 2 was an 85-year-old female who had undergone extraction of stumps of right premolar and molar teeth in the mandible because of a throbbing intermittent pain in the right mandible. She was referred to our hospital because the pain was not relieved even though the wound was cured. The pain nearly disappeared by the administration of Neurotropin®. However, she was suspected to be suffering from symptomatic trigeminal neuralgia because of the long duration of pain, no trigger zone, and severe right hypoacusis. MRI revealed that an acoustic nerve tumor was compressing the right trigeminal nerve at the root entry zone. She was not operated on because of her age and the hypoacusis was considered to be irreversible, and so the pain was controlled. It is not always easy to distinguish between typical and symptomatic trigeminal neuralgia by means of only clinical findings. Therefore, it is useful to ascertain the presence of an intracranial process by MRI in order to make an accurate diagnosis of patients with trigeminal neuralgia or atypical facial pain.
  • 山崎 佐知子, 虎谷 茂昭, 神田 拓, 竹末 奈七子, 吉田 真希, 岡本 哲治
    2011 年 60 巻 3 号 p. 271-277
    発行日: 2010/06/10
    公開日: 2011/08/31
    ジャーナル 認証あり
    Monoclonal gammopathy of undetermined significance (MGUS) is a pre-malignant plasma cell proliferative disorder, characterized by the presence of a serum M-protein and low number of plasma cells in the bone marrow without any evidence of end-organ damage related to multiple myeloma. However, MGUS undergoes a transition to multiple myeloma, AL amyloidosis or another plasma cell dyscrasia at the rate of about 1% a year during follow-up.
    We encountered a case of MGUS associated with AL amyloidosis diagnosed by morphological and immunological examination. The patient was an 86-year-old woman who had multiple nodules corresponding to the lower lip, the buccal mucosa, the floor of mouth and the soft palate. Histopathologically, the nodules were diagnosed as AL amyloidosis because of positive reaction against IgG κ type antibodies. Furthermore, quantitative analysis of immunoglobulin and immunoelectrophoresis of the patient's urine revealed increased IgG κ type monoclonal protein. Therefore, we carried out bone marrow aspiration and finally diagnosed that this case was caused by ‘MGUS’.
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