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Volume 62, Issue 2
Displaying 1-3 of 3 articles from this issue
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ORIGINAL ARTICLE
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Yumiko OHBAYASHI, Minoru MIYAKE, Yuko MINAMI, Fumi SAWAI, Takehiro MIK ...2013 Volume 62 Issue 2 Pages 181-186
Published: 2013
Released on J-STAGE: October 10, 2013
JOURNAL RESTRICTED ACCESSBACKGROUND: Oral lichen planus (OLP) is a chronic inflammatory disease and morbidity is 1.2%. Irsogladine maleate (IM) is a drug used for the treatment of gastritis and peptic ulcers. Some reports have shown that IM has been useful for aphthous stomatitis and OLP. However, there are no reports on the clinical response of IM for OLP statistically. This study investigated statistically the therapeutic effect, relevant clinical factors and side effects to clarify the usefulness of IM against OLP.
METHODS: The study group consisted of 22 patients who had OLP from January 2007 to October 2010. Irsogladine 2mg × 2/day was administered orally. The end-point of the curative effect was assumed to be “pain”, “number of affected sites”, and “area”, and each of these was scored. Efficacy was evaluated statistically based on the total score pre- and post-administration.
RESULTS: The means of the pre-administration scores for “pain”, “number of affected sites” and “area” were statistically different from the post-administration scores. The total post-administration scores correlated with the total pre-administration scores (p = 0.003). The regression equation obtained in the study was (total post-administration score = 0.693×total pre-administration score−1.492). Side effects were not seen in any case.
CONCLUSION: IM was safe and effective for patients with OLP.View full abstractDownload PDF (449K)
CASE REPORTS
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Gentarou FUJITA, Masahiro MICHIZAWA, Tomoaki IMAI, Naonori YAMAMOTO, Y ...2013 Volume 62 Issue 2 Pages 187-191
Published: 2013
Released on J-STAGE: October 10, 2013
JOURNAL RESTRICTED ACCESSA case of peripheral ameloblastoma with massive bone resorption was reported. A 73-year-old woman presented with a swelling on the edentulous alveolus in the left premolar region of the lower jaw. It was a 20 × 15 mm, elastic hard mass with a smooth and reddish surface. An X-ray examination showed massive resorption of the underlying jaw bone. A tissue biopsy revealed the lesion was peripheral ameloblastoma. The tumor was excised. Because the tumor had a fibrous capsule, it was easily removed from the jaw bone. Thus only the superficial part of the bone was removed with a dental round bar. Histologically, the excised tumor was follicular and acanthomatous ameloblastoma largely surrounded by fibrous connective tissue. It was directly contiguous with the gingival epithelium. Peanut agglutinin reactivity and cytokeratin 19 immunoreactivity indicated the tumor was not central ameloblastoma or basal cell carcinoma, respectively. The tumor cells showed a Ki-67 labeling index (13.7%) similar to the previously-reported central-ameloblastoma cells, suggesting that the aggressive nature of the tumor led to the massive bone resorption. As of 2 years postoperatively, there is no evidence of recurrence and the patient's progress is good.View full abstractDownload PDF (789K) -
Akihiro DOHI, Kiyoshi HARADA, Masatoshi HIGUCHI, Yoshio NAKANO, Mikio ...2013 Volume 62 Issue 2 Pages 192-197
Published: 2013
Released on J-STAGE: October 10, 2013
JOURNAL RESTRICTED ACCESSA case of subcutaneous and mediastinal emphysema during extraction of an impacted lower third molar is reported. The patient was a 24-year-old woman, who underwent molar extraction under local anesthesia. During the procedure, the patient complained of a slight sore throat, but the extraction was finished with short breaks. After the extraction, the face towel was removed, and it was found that her left eyelid, left cheek, bilateral submandibular regions, and left supraclavicular fossa were red and swollen. A pleural friction rub could be felt in the supraclavicular fossa, and she complained of respiratory discomfort. A computed tomographic scan revealed aerodermectasia from the left temporal region to the bilateral cervical region, as well as mediastinal emphysema extending to the pericardium. The patient was hospitalized and given a drip intravenous infusion of antibiotics. She made satisfactory progress and recovered on day 11. It is very important to consider the possibility of emphysema in such cases and to know how to treat it appropriately.View full abstractDownload PDF (637K)
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