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Volume 63, Issue 3
Displaying 1-5 of 5 articles from this issue
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Takashi UESUGI, Tadaharu KOBAYASHI, Yoshiyuki TAKATA, Daichi HASEBE, T ...2014 Volume 63 Issue 3 Pages 251-259
Published: 2014
Released on J-STAGE: August 05, 2014
JOURNAL RESTRICTED ACCESSThe purpose of this study was to investigate patients with chief complaints of snoring and/or sleep apnea in our clinic for the past decade. The subjects were 881 patients (637 males and 244 females) with a mean age ± SD of 48 ± 15 years. Mean body mass index was 24.7 kg/m2. Overnight polysomnographic evaluation was performed in 563 subjects, and the mean value of apnea hypopnea index was 23.6 times/h. The proportion of males with moderate to severe obstructive sleep apnea syndrome (OSAS) was 69.9%, which was higher than that of females (47.6%), and the incidence of moderate to severe OSAS increased with age in both males and females. For treatment, an oral appliance (OA) was provided for 369 subjects (41.9%) and surgical treatment such as laser-assisted uvulopalatoplasty or orthognathic surgery was performed in 41 subjects (4.7%) in our clinic. Nasal continuous positive airway pressure was used to treat 154 subjects (17.5%), and 67 subjects (7.6%) were treated for nasal congestion and/or tonsillar hypertrophy by an otorhinolaryngologist. The remaining 250 subjects (28.4%) refused treatment for sleep disordered breathing. The efficacy rate in subjects treated with an OA was 60.5%, though the efficacy rate in severe OSAS subjects (47.2%) was lower than those in mild and moderate OSAS subjects (54.3% and 72.4%, respectively). OA treatment is highly effective for moderate OSAS subjects. Therefore, it is important to classify the severity.View full abstractDownload PDF (1061K) -
Kiyoshi NAGAI, Hiromasa YOSHIKAWA, Yoshinori HIGUCHI2014 Volume 63 Issue 3 Pages 260-268
Published: 2014
Released on J-STAGE: August 05, 2014
JOURNAL RESTRICTED ACCESSDysgeusia, xerostomia and stomatitis are oral diseases that may be caused by conventional treatment for chronic hepatitis C, which is a combination of peg-interferon and ribavirin. Recently, triple-drug therapy with telaprevir added as a protease inhibitor is used for treating chronic hepatitis C, but there is no report on oral diseases caused by this triple-drug therapy yet. This study evaluated the prevalence of oral diseases with this triple-drug therapy. Fifty patients completed the data collection survey. Prevalence of dysgeusia, xerostomia and stomatitis were 78.0% (32 out of 41 patients), 80.5% (33 out of 41) and 47.9% (23 out of 48) respectively, which were higher than with conventional treatment. It is suggested that telaprevir worsened oral diseases, because all oral symptoms recovered gradually after the therapy.
To estimate the cause of dysgeusia, we examined the relationship between dysgeusia and objective parameters such as salivary flow rate, serum iron level, serum zinc level and hemoglobin in 11 patients during 12 weeks of adding telaprevir. Ten patients reported dysgeusia symptoms. Dysgeusia and xerostomia worsened at 8 weeks and 12 weeks, respectively. Unstimulated whole salivary flow rate (UWS), serum zinc level and hemoglobin were reduced to less than the normal level. It is considered that reduction of UWS and serum zinc level caused subjective dysgeusia symptoms. It is also considered that reduction of serum zinc level resulted from anemia. Xerostomia is considered to result from reduction of UWS. It is suggested that oral symptoms as well as systemic symptoms should be monitored for evaluating this therapy.View full abstractDownload PDF (1225K) -
Takeshi WADA, Itaru TOJYO, Yukari SHINTANI, Masai YAMADA, Kenji NEGORO ...2014 Volume 63 Issue 3 Pages 269-274
Published: 2014
Released on J-STAGE: August 05, 2014
JOURNAL RESTRICTED ACCESSThe purpose of this study is to evaluate the usefulness of a protocol based on a surgical extraction procedure (removal of the sharp edge of the alveolar bone ridge and complete coverage of the extraction socket with the mucoperiosteal flap), and local and systemic infection control, in preventing the development of bisphosphonate-related osteonecrosis of the jaws after tooth extraction.
Fifty-one patients with nitrogen-containing bisphosphonates, including 33 high risk patients, underwent 106 tooth extractions according to our protocol. Routine follow-ups were made after the tooth extractions were performed, and the existence of inflammation, fistula and discharge of pus, and exposure of necrotic bone were inspected.
The average follow-up periods were 19 months (2∼58 months), and no cases of bisphosphonate-related osteonecrosis of the jaw were noted. It seemed that this protocol is useful to prevent bisphosphonate-related osteonecrosis of the jaws, even if it is a high risk group.View full abstractDownload PDF (574K)
CASE REPORTS
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Futoshi IWAKI, Masanobu OHNISHI2014 Volume 63 Issue 3 Pages 275-278
Published: 2014
Released on J-STAGE: August 05, 2014
JOURNAL RESTRICTED ACCESSA case of aneurysmal bone cyst of the mandible with mental neuropathy is reported. A 55-year-old woman complained of numbness in her right lower lip. MR imaging showed a well-defined mass lesion in the right mandible. Histopathological examination of the biopsy specimen suggested that the lesion was an aneurysmal bone cyst. Angiograms of the maxillary artery revealed a high-flow cystic lesion involving the right mandible supplied by the inferior alveolar artery. Superselective embolization of the feeding artery was performed before the operation. Surgical excision of the aneurysmal bone cyst was performed immediately after the embolization. The amount of bleeding during the operation was 25 ml. The patient has remained asymptomatic for 6 years after the procedures.View full abstractDownload PDF (595K) -
— Report of a case —Eriko SHIBAYAMA, Mitsuyoshi IINO, Hiroyuki YAMADA, Mami SUZUKI, Yoko Y ...2014 Volume 63 Issue 3 Pages 279-283
Published: 2014
Released on J-STAGE: August 05, 2014
JOURNAL RESTRICTED ACCESSTranscatheter arterial embolization (TAE) has been used with increasing frequency in oral and maxillofacial surgery to achieve hemostasis in patients with various lesions such as aneurysms, arteriovenous malformations and hemangiomas. In this paper, we report the successful use of TAE to control arterial bleeding that started during removal of an impacted mandibular third molar. A 32-year-old male underwent elective removal of bilateral impacted mandibular third molars. During removal of alveolar bone around the left third molar, arterial bleeding suddenly occurred and could not be controlled using oxidized cellulose gauze and electrocoagulation. The bleeding was mild after 1 hour of digital pressure with gauze packing, but did not stop. The next day, TAE of the left inferior alveolar artery was performed using the Seldinger technique. During the procedure, leakage of radiopaque dye from a branch of the inferior alveolar artery was observed, indicating that the bleeding was caused by injury to this arterial branch. The inferior alveolar artery and the bleeding arterial branch were embolized with gelatin sponge and microcoils. Forty-two days after TAE, the left mandibular third molar was removed without any further complications.View full abstractDownload PDF (615K)
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