Synthesiology
Online ISSN : 1882-7365
Print ISSN : 1882-6229
ISSN-L : 1882-6229
Volume 8, Issue 3
Displaying 1-8 of 8 articles from this issue
Highlights of the Papers in Synthesiology
Research papers
  • — Interdisciplinary research between semiconductor fabrication technology and biological electron microscopy —
    Toshihiko OGURA, Hidetoshi NISHIYAMA, Mitsuo SUGA, SATOU Chika ...
    2015 Volume 8 Issue 3 Pages 116-126
    Published: 2015
    Released on J-STAGE: September 04, 2015
    JOURNAL FREE ACCESS
    Protein complexes in cells and tissues play critical roles in various physiological functions, including embryogenesis and signal processing. To observe the dynamics of protein complexes, high resolution and high throughput electron microscopy (EM) in aqueous solution is required. However, standard EM requires the sample to be in a vacuum. With ASEM, an inverted scanning electron microscope (SEM) observes the wet sample from beneath an open dish while an optical microscope (OM) observes it from above. The disposable dish with a silicon nitride (SiN) film window can hold a few milliliters of culture medium, allowing various types of cells to be cultured in a stable environment. This system was used for the development of in situ correlative OM/SEM immuno-microscopy in liquid. We observed a dynamic string-like gathering of STIM1 on the endoplasmic reticulum in Jurkat T cells in response to Ca 2+ store depletion. We have also observed filamentous-actin (F-actin) and tubulin in the growth cones of primary-culture neurons as well as in synapses. We monitored in-situ electrochemical reactions in electrolytes, and melting and solidification of solder using ASEM.
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  • — Establishing metrological traceability system for AC voltage standard —
    Hiroyuki FUJIKI, Yasutaka AMAGAI, Hitoshi SASAKI
    2015 Volume 8 Issue 3 Pages 127-144
    Published: 2015
    Released on J-STAGE: September 04, 2015
    JOURNAL FREE ACCESS
    Thermal voltage converters have been widely used in the electric standard field as a major method to derive AC voltage standards from DC voltage standards. However, few organizations have skills for fabricating thermal voltage converters. Furthermore, establishing AC-DC voltage standards has been constrained by the lack of high-quality thermal converters. High-quality thermal converters are used only by national metrology institutes (NMIs), because conventional thermal converters are too fragile for many calibration service providers. The National Institute of Advanced Industrial Science and Technology (AIST) has developed new thin film multijunction thermal converters(TFMJTCs) to realize a reliable high-performance thermal converter. Development of a durable TFMJTC with a heater on an aluminum nitride (AlN) chip would be a significant contribution to Japanese calibration service providers.
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  • — Photonics contributes to a sustainable society in the “photon century” —
    Hiroyuki NIINO
    2015 Volume 8 Issue 3 Pages 145-157
    Published: 2015
    Released on J-STAGE: September 04, 2015
    JOURNAL FREE ACCESS
    Green Photonics is expected to reduce energy consumption and pollution associated with a broad range of manufacturing processes. The paper is a study on the development of laser-based methods and their applications. High precision surface processing of various materials is a key technology for practical industrial applications. Well-defined micro-fabrication with high-speed and high-quality treatment of materials was performed by laser irradiation. The technical challenges are particularly great in this area, but recent developments in laser processing have opened up new frontiers. Due to advances in laser processing systems, and greater understanding of the phenomenon of diverse excited states generated by laser irradiation, these methods can be considered mature and versatile techniques that present some key benefits over other more established fabrication techniques.
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  • — Toward end-user development in manufacturing industry —
    Hiroyuki SAWADA, Hitoshi TOKUNAGA, Yoshiyuki FURUKAWA
    2015 Volume 8 Issue 3 Pages 158-168
    Published: 2015
    Released on J-STAGE: September 04, 2015
    JOURNAL FREE ACCESS
    Manufacturing companies are increasingly being called upon to fulfill various social demands, such as rapid delivery, multiobjective production, quality assurance and traceability security. The introduction of information technology is needed to meet these demands and to strengthen competitiveness. However, the development, operation, and maintenance costs of IT systems are too high for their introduction into small and medium-sized companies. To encourage manufacturing companies to introduce IT systems, we have developed an IT system development framework, called "MZ Platform", which enables manufacturing industry workers to construct and operate IT systems without professional IT knowledge. We describe our research and development approaches and dissemination activities, and discuss the effectiveness of the MZ Platform.
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