巻号一覧
100 巻 (1970)
- 4 号 p. 305-
- 3 号 p. 201-
- 2 号 p. 99-
- 1 号 p. 1-
100 巻, 4 号
選択された号の論文の9件中1～9を表示しています
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Yoichiro Sasai1970 年 100 巻 4 号 p. 305-313
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーThe histochemical property of the hyaline material was studied in a case of hyalinosis cutis et mucosae. Alcian blue, azure A and periodic acid Schiff were used for staining mucopolysaceharides. Bromphenol blue was employed for detection of basic proteins. In a further attempt to identify various polyanions histochemically, staining was carried out with alcian blue containing different concentrations of electrolytes. Methylation, saponification, mild acid hydrolysis and digestions by hyaluronidase and sialidase were also employed. The results obtained suggest that the hyaline material found in the case of hyalinosis cutis et mucosae contains a sialic acid-containing mucoprotein.抄録全体を表示PDF形式でダウンロード (4049K) -
Jun Kusakari, Yukio Yoshino, Jiro Hozawa, Shuichi Katagiri1970 年 100 巻 4 号 p. 315-325
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーThe mode of function of the otolith organ was investigated by recording action potentials from the first order neuron of the guinea pig. In the present experiment ‘nose-down’ unit was recorded more frequently than ‘nose-up’ unit, whereas ‘side-up’ unit was almost equal in number to ‘side-down’ unit. The reaction of the otolith organ was much influenced by tilting speed-more remarkable in slow tilt than in rapid one. Two different kinds of units were noted in sustained tilt, one showed remarkable adaptation and the other showed moderate adaptation. They were recorded in the ratio of 1:5. In galvanic stimulation every unit showed enhancement in cathodic stimulation and suppression in anodic stimulation. Two kinds of adaptation were also found in the same fashion as in tilting stimulation. It is the precent authors' working hypothesis that the difference of adaptation is due to different size of the nerve fibers.抄録全体を表示PDF形式でダウンロード (1788K) -
Noriyoshi Hayasaka, Nobuaki Sasano1970 年 100 巻 4 号 p. 327-347
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーHistopathological findings of pancreas freshly obtained from 108 autopsy cases were analyzed and individual lesions were correlated with vascular and ductal patterns revealed by microradiography. As the intralobular artery was demon-strated as a terminal artery, its functional and/or organic occlusion was expected to produce focal atrophy, parenchymal necrosis and fibrosis of lobular unit. Atrophy of acinar cells leading to replacement by isolated fat cells developed presumably from disturbance of systemic arterial circulation. Venous stasis seemed to be responsible for the formation of pseudolobules.
Organic and/or functional obstructions in any part of the pancreatic duct caused various lesions of pancreatitis. Periductal location of focal necrosis and cell infiltration was regarded as a result of pancreatic juice leakage. Because the peripheral range of the pancreas was abundant in ductules, fat necrosis and fibrosis probably of ductal origin preferred the periphery.
It was presumed that the ductal and vascular factors could interact each other in producing pancreatitis and both might even precipitate serious damages of the pancreas.抄録全体を表示PDF形式でダウンロード (4826K) -
Shiro Kosaka1970 年 100 巻 4 号 p. 349-358
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーSerum total sulfhydryl level (SH-level) was determined in 285 cases of rheumatoid arthritis and other allied diseases and of healthy subjects. The SH-level was within the normal limits in 28 of 33 cases of rheumatoid arthritis. However, it was slightly lower than that of the controls. The SH-level was subnormal in the remaining 5 cases. These 5 cases showed high titer of rheumatoid factors and an increase in the amount of IgM. The results suggest that the formation of macroglobulin, particularly that of rheumatoid factor is related to a decrease of SH-level. When L-cysteine was injected into the joint cavity of a patient, IgM disappeared temporarily from the synovial fluid at 30min and 3hr. Glutathione had not such an effect. Thus, different SH-compounds seem to exert different effects on the organism.抄録全体を表示PDF形式でダウンロード (450K) -
Kozo Watanuki, Kazutomo Kawamoto, Shuichi Katagiri1970 年 100 巻 4 号 p. 359-368
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーThe surface structure of the cochlear duct was investigated on experimental animals with light microscope by means of the silver nitrate staining, which gave a fine contrast. The horizontal processes of the interdental cells (superficial cells of the spiral limbus) were rectangular in shape and they formed a radiating mosaic pavement under the inserted portion of the tectorial membrane. The inner spiral sulcus cells became smaller towards the border cells at the free surface. The reticular lamina showed, as a whole, a very regular framework composed of hairs and supporting cells. At the border between Hensen's and Claudius's cells, one row of spirally arranged epithelial cells was observed. The spiral prominence cells and the marginal cells of the vascular atria were clearly viewed from the side of the scala media. Between the marginal cells of the vascular atria and the spiral prominence cells as well as the epithelial cells of the Reissner's membrane, some rows of large spindle-shaped cells were observed on the endolym-phatic surface running parallel with the vascular atria from the base to the apex of the cochlea.抄録全体を表示PDF形式でダウンロード (3605K) -
Tooru Nakao, Yasuo Chiba, Shunzo Chiba1970 年 100 巻 4 号 p. 369-373
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーAntiviral activity is demonstrated in saliva of patients with mumps by hemagglutination inhibition (HI) test. HI antibody against mumps virus in saliva consists mainly in IgA.抄録全体を表示PDF形式でダウンロード (422K) -
Chikako Sato, Masatoshi Sakka1970 年 100 巻 4 号 p. 375-381
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーHuman lymphocytes in heparinized blood were collected through a tetoron fiber column. About 5×105 lymphocytes in a milliliter of Eagle's essential moiium containing 20% autoserum were cultured with phytohemagglutinin (PHA) and exposed to x-irradiation. The results were as follows: (1) Morphological blast formation was not affected by x-rays below 300R. About 60% of lymphocytes could transform even after an exposure to 2, 000 R. (2) Autoradiography after continuous labeling with 3H-thymidine proved that entering of the lymphocytes into the DNA synthetic phase was suppressed by radiation. The percentage of cells entering the first DNA synthesis was dependent on the radiation dose; 96, 92, 73, 48, 37, 42 and 36% after the irradiation of 0, 150, 300, 500, 1, 000, 1, 500 and 2, 000R, respectively, 2 to 3 hours after the addition of PHA. (3) Accumulation of mitosis by coiehicine was prevented by irradiation depending on doses; 72, 36, 37, 8, 8 and 5% of original lymphocytes entered the first mitosis after the irradiation of 0, 140, 300, 500, 1, 000 and 2, 000R, respectively, at 2 to 3 hours culture. At about 2, 000R, not more than 10% of stimulated lymphocytes entered mitosis in 5 days' incubation.抄録全体を表示PDF形式でダウンロード (312K) -
Jiro Kaizawa, Isao Takahashi1970 年 100 巻 4 号 p. 383-394
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーThe rat monosynaptic reflex shows marked depression in response to repetitive stimulation of low frequency, which is called ‘low frequency depression’. The site and the mechanism of this depression was studied and discussed in relation to the characteristic features of the rat spinal cord.
1) The depressive effect of the repetitive stimulation is referable to the motoneurons invaded by the impulses, regardless of number of the mediating synapses, and not by some inhibitory agent on the outside of the impulse circuit. 2) Therefore, in the outlook a synchronous wave showed more marked depression than a dispersed wave, which explained the eminence of the depression of monosynaptic reflex. 3) The depression was caused by two factors: cessation and delaying of a unit discharge in terms of unit activity. The delaying consists of two factors: gradual retreat of firing point owing to reduced EPSP and the skipping from insufficient EPSP to succeeding EPSP.抄録全体を表示PDF形式でダウンロード (2102K) -
Hajime Sugihara1970 年 100 巻 4 号 p. 395-409
発行日: 1970年
公開日: 2008/11/28
ジャーナル フリーThe effects of SU-4885 on the rat adrenal cortex by oral administration of 50mg/kg, single or daily for 10 days, were morphologically studied particularly with histochemical methods for the enzyme and lipid.
Lipid depletion with fragmentation of droplets throughout the zona fasciculata in rats with single administration conformed to the pattern of adreno-cortical response to an acute moderate stimulus.
Reduced activity of secondary alcohol dehydrogenase, fragmentation of lipid droplets, and acidophilic and trabecular changes in the cell cords were observed in the inner fasciculata following a single or daily administration for 10 days. The medication apparently brought about hypersecretion of adrenocortical steroids, which was similar to the effect of ACTH administration.
Reduced activity of secondary alcohol dehydrogenase, which reflected the transformation of cholesterol in the steroid biosynthesis, was always observed in the zona fasciculata following the administration of SU-4885 or ACTH. The result might indicate that the administration inhibits some decrease in the steroid biosynthesis from cholesterol possibly through the ‘short route’.抄録全体を表示PDF形式でダウンロード (2202K)
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