巻号一覧
107 巻 (1972)
- 4 号 p. 303-
- 3 号 p. 203-
- 2 号 p. 105-
- 1 号 p. 1-
107 巻, 2 号
選択された号の論文の14件中1～14を表示しています
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MASANA OGATA, KATSUMARO TOMOKUNI, SHINSAKU WATANABE, HIROKAZU OSAKI, M ...1972 年 107 巻 2 号 p. 105-114
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーProperties of the residual catalase of erythrocytes in the blood of Japanese acatalasemia are almost the same as those of the normal catalase as judged by the elution pattern by Sephadex G-100 gel filtration, affinity toward the substrate, the sedimentation pattern by density gradient centrifugation, and the heat stability. Japanese acatalasemia is different from Swiss one derived from the literature (Matsubara et al. 1967) on the fact that the residual catalase activity is heat-stable, and the catalase activity in reticulocytes is extremely low in Japanese acatalasemia. The catalase activity of Japanese hypocatalasemia (heterozygote) is also lower than that of Swiss case in the literature (Aebi et al. 1961). The results are discussed in terms of the possible difference in the genetic mechanism of the Japanese and Swiss acatalasemias.抄録全体を表示PDF形式でダウンロード (531K) -
MAKOTO SEIJI, TAKESHI OHSUMI1972 年 107 巻 2 号 p. 115-125
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーA statistical study was made on 501 cases of malignant melanoma collected from Japanese literature from 1961 to 1970. Malignant melanoma is still found less in Japanese than in white racial groups but its incidence indicates a definite upward trend in recent years. The incidence of malignant melanoma according to sex is slightly higher in the male group than the female. The distribution of this disease by age presents no significant difference by sex and there are two high incidence peaks in the third and sixth decades in this series of study. The most frequent sites of involvement are the skin (28.5%), mucous membrane (27.0%) and eye (23.9%). In skin lesions, the most common primary site is the lower extremities, especially the sole of the foot. Among the mucous lesions, the mouth is the most popular site of involvement. The relationship between the onset of malignant melanoma and the number of the melanocytes in the different parts of the body has been studied. There seems to be a parallel relationship between the incidence of melanoma and the number of melanocytes per unit skin area. An exceptionally high incidence of melanoma was observed on the sole. The incidence of metastasis appears to be higher in the older age group than in the younger. There were high incidences of metastasis at the trunk, lower limbs and gastrointestinal tract. Fifty-five patients (63%) gave a history of preexisting pigmented lesions at the site of the primary melanoma.抄録全体を表示PDF形式でダウンロード (450K) -
MAKOTO TAMAI, TETSURO OGAWA1972 年 107 巻 2 号 p. 127-142
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーIn chloralose-anesthetized cats, electrical stimulation of the optic tract evoked a negative-positive field potential wave at the surface of the ipsilateral superior colliculus which reversed to a positive-negative wave at the deeper part of the superficial gray layer. The maximal amplitude of the deep positivity was reached at the optic layer. Cortical stimulation of visual and surrounding areas elicited similar field potentials in the ipsilateral superior colliculus. Reversal in polarity occurred at the same depth as did for the tract-evoked field potential. In general, stimulation of cortical areas surrounding the visual cortex, for example, the posterior suprasylvian gyrus, gave rise to a larger response than stimulation of the visual cortex. Reversible inactivation of the cortical visual and adjacent areas by cooling resulted in a reduction of the tract-evoked field potential with a gradual recovery to the initial amplitude after removal of the cooling agent. This finding indicates that the geniculocortico-tectal pathway contributes the generation of collicular response to stimulation of the retinotectal pathway. Topographical interrelationships between the effective cortical area and the superior colliculus were examined with the amplitude of cortically evoked collicular responses as an index. It was revealed that the junctional part between the lateral and postlateral gyri was related to the posterior part of the superior colliculus and that the upper part of the postsuprasylvian gyrus was associated with the anterior part of the superior colliculus. As to interaction between cortico-tectal and retino-tectal inputs, it was found that preceding stimulation of the effective cortical areas produced an initial facilitation from 50 to 200 msec followed by a depression of collicular response to optic tract stimulation lasting for as long as 500 msee.抄録全体を表示PDF形式でダウンロード (864K) -
SHINICHIRO ARASHIMA, ICHIRO MATSUDA1972 年 107 巻 2 号 p. 143-147
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーA case is reported of a 2-month-old female infant with cabamyl phosphate synthetase deficiency in whom persistent vomiting appeared 7 days after birth, with irregular eye movement. Failure to thrive, hypotonia and a generalized atrophy of the brain were observed. This is the fourth case of carbamyl phosphate synthetase deficiency in the literature.抄録全体を表示PDF形式でダウンロード (842K) -
MAKOTO SEIJI, HIDEKO ITAKURA1972 年 107 巻 2 号 p. 149-157
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe effect of deoxycholate (DOC) on smooth-surface membranes was studied by means of electron microscopy. The smooth-surface membranes were isolated from Harding-Passey mouse melanomas and treated with 0.05% DOC. In the sectioned specimens, the untreated smooth-surface membranes appear as unit membranebound, closed vesicles. The unit membranes measure 50 Å across. The treated membranes showed significant vesiculation and swelling. In some parts many small vesicles are grouped in a cluster and enclosed by a membrane. A few to several unit membranes are stuck together to form myelin-like structures. In the negatively stained specimens, varying degrees of smooth-surface membrane vesiculation are apparent. Most large vesicles are found to exhibit myelin-like lamellar structures. From these observations, DOC appears to cause a vesiculation and swelling of the smooth-surface membranes but does not appear to destroy the unit membrane structure. There were a few myelin-like lamellar structures which were thought to have been produced by uniting several unit membranes.抄録全体を表示PDF形式でダウンロード (4378K) -
MASATAKA MARUYAMA, SHISHO ICHIOKA, TADAYOSHI TAKEMOTO, TAIGORO KONDO, ...1972 年 107 巻 2 号 p. 159-165
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーAn attempt to measure a lesion in the stomach through a new model of fibergastroscope (FGS-BLG) is reported. FGS-BLG is equipped with the gauge which is observed as a bright line above the image on view of the scope. The length of this line always corresponds with the length of 1cm on the surface cf the gastric mucosa on which the object lens is just focused. The effective range of the distance between the lesion and the object lens is approximately 2 to 5cm, although the lesions near the pyloric ring and on the posterior wall of the upper portion of the corpus are not always satisfactorily measured because the distance is generally too long and too short respectively. The gauge is easy to photograph, so that the size of lesion in the stomach can be satisfactorily measured even on the developed picture. This device will be widely applicable.抄録全体を表示PDF形式でダウンロード (1933K) -
TAKAYOSHI TOYOTA, SHIN-ICHIRO SATO, AKIRA OHNEDA, YOSHIO GOTO1972 年 107 巻 2 号 p. 167-172
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe present study was undertaken to see whether the function of the pancreas in diabetics is improved by the exogenous insulin treatment. In seven diabetic patients, bonito insulin was injected every day until the urine sugar became negative, and the diurnal change of plasma insulin was estimated before insulin injection and during the urine sugar-free period. Plasma insulin area, calculated by our formula, increased in six of the patients. As bonito insulin does not show any immunological cross-reaction with pork, beef and human insulin, this increase in plasma insulin area after the bonito insulin treatment may be due to an improvement of the impaired function of the pancreas抄録全体を表示PDF形式でダウンロード (322K) -
KINJI ISHIKAWA, TAKASHI HANEDA, SHIGEAKI IKEDA, KAI TSUIKI, KOZUI MIYA ...1972 年 107 巻 2 号 p. 173-183
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーPeripheral arterial dilution curves were recorded by earpiece densitometer following injection of dye into a femoral vein, pulmonary artery, left atrium and aortic root in 14 cases with aortic insufficiency and 56 control cases without heart disease during routine cardiac catheterization. Six indices (tpd/ta, tpd/tap, Spread/ta CL/Cr, Cp+ap/Cp, Cp10/Cp) which have been advocated for diagnosis of mitral insufficiency or left-to-right shunt were calculated from the dilution curves. Cp10/Cp showed significantly higher values in aortic insufficiency than in controls, while there were no significant differences in the other 5 indices between both groups. Aortic regurgitation was quantitated by continuous injection of dye into the aortic root and recording from the left ventricle, and the values were compared with Cp10/Cp. There was a positive correlation between Cp10//Cp and aortic regurgitation. It was concluded that the increase in Cp10/Cp is resulted from a flatness of its peak without prolongation of downslope of the dye curve in aortic insufficiency, so that the index is useful for diagnosis of this disease.抄録全体を表示PDF形式でダウンロード (512K) -
KAORU SAGISAKA, KAZUO TOKIWA, SYUSAKU KATSURA1972 年 107 巻 2 号 p. 185-189
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーIt was reported previously that proteolytic enzyme-treated M red cells lost their reactivity completely with only anti-M IgG antibody. In this paper, M red cells treated with trypsin for 45 min or 3 hr were used to prepare group-specific anti-M IgG and -N IgG antibodies as an adsorbent. It was revealed that M red cells treated for 3 hr could adsorb anti-N antibody in anti-M IgG fraction obtained from crude anti-M serum by DEAE-cellulose column chromatography. The potency of the red cells to adsorb anti-N IgG antibody was similar to that of normal N red cells. Anti-N IgG antibody was prepared by heat-eluting trypsin-treated M red cells sensitized with anti-N fraction. However, the experiments with M red cells treated for 45 min showed unsatisfactory results. It was due to the red cells which could still react with high-titered anti-M IgG antibody but not sufficiently with anti-N IgG antibody.抄録全体を表示PDF形式でダウンロード (322K) -
NORIO TAIRA, KAZUHIKO IWATSUKI, KOROKU HASHIMOTO, HACHIHIKO HIRAYAMA1972 年 107 巻 2 号 p. 191-192
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーA small amount (3-10 μg) of a toxin isolated from the Japanese ivory shell (Babylonia japonica) was injected into the caudal vesical arteries of the dog bladder in situ. This greatly diminished the bladder contraction in response to pelvic nerve stimulation and antagonized that to 1, 1-dimethyl-4-phenylpiperazinium iodide, a nicotinic ganglionic stimulating agent. The toxin was ineffective on the contractile response to 4-(m-chlorophenylcar bamoyloxy)-2-butynyltrimethylammonium chloride, a muscarinic ganglionic stimulating agent. Thus, the toxin appears to be highly specific in blocking the nicotinic receptors at the parasympathetic ganglia of the dog bladder.抄録全体を表示PDF形式でダウンロード (115K) -
TOSHIMI SUZUKI, KEIKO OYAMA, TAKASHI NAKAMURA1972 年 107 巻 2 号 p. 193-195
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーMicrocirculation in the mesentery of rats with DCA induced hypertension was observed in vivo by high-speed cinematography. Tortuosities and lumina narrowings of the arterioles, venules and capillaries were observed. Red blood cells flowing in the capillaries smaller than 4.3 μ in internal diameter took a crushed, elongated cylindrical shape and the ratio of length/diameter was 2.6-4.6. Deformation of red blood cells when passed through narrow capillaries was thought to be an important causative element of hemolytic anemia.抄録全体を表示PDF形式でダウンロード (1001K) -
SHIGETOSHI CHIBA, KATSUMI KUBOTA, KEITARO HASHIMOTO, KOROKU HASHIMOTO1972 年 107 巻 2 号 p. 197-198
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーTen mongrel dogs were used for study of effects of hyperpotassemia on AV conduction, utilizing the direct perfusion technique of the AV node artery in situ. Infusion of potassium at the concentration about 7 to 9 mEq/liter for 1 to 3 minutes induced incomplete AV block, i.e., first and second degree AV blocks, and occasionally bigeminy. The infusion of potassium at the concentration more than 10 mEq/liter produced complete AV block, i.e., AV dissociation with ventricular tachysystoles and occasionally induced ventricular fibrillation.抄録全体を表示PDF形式でダウンロード (88K) -
SHINOBU MATSUDA, HISANAGA IGARASHI, TAKUSEI UMENAI, TAKESHI SASAKI, NA ...1972 年 107 巻 2 号 p. 199-200
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーThe sensitivity of the solid-phase radioimmunoassay (RIA) for detecting Australia (Au) antigen, which was introduced by Abbott Laboratories as Ausria-125 kit, was compared with that of other assay methods using the standard mixture of human sera containing Au antigen. The RIA was more sensitive in detecting Au antigen contained in human sera.抄録全体を表示PDF形式でダウンロード (116K) -
NAKAO ISHIDA, TAKUSEI UMENAI, RYOICHI SHIRACHI, TAKEHIKO SHIRATORI, JI ...1972 年 107 巻 2 号 p. 201-202
発行日: 1972年
公開日: 2008/11/28
ジャーナル フリーAge distribution of per cent positives of Australia (Au) antigen in several counties of Miyagi Prefecture was compared. Although the average incidence throughout the Prefecture was 1.7%, the highest incidence of 4.5% was found in Kurikoma district and the lowest incidence of 0.3%, in Marumori district. For the explanation of such a difference, no particular geographic and anthropological difference could be found. However, the age distribution of antibody was different between these two districts.抄録全体を表示PDF形式でダウンロード (134K)
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