巻号一覧
109 巻 (1973)
- 4 号 p. 309-
- 3 号 p. 205-
- 2 号 p. 97-
- 1 号 p. 1-
109 巻, 1 号
選択された号の論文の13件中1～13を表示しています
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KAORU SAGISAKA, KAZUO TOKIWA1973 年 109 巻 1 号 p. 1-6
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe presence of M and N antigens in the blood components other than the red cells and various tissues has not been settled yet. The elution method in combination with antiglobulin test reported by the present authors has been used for grouping the stains of the leucocytes, platelets, fibrin, and thymic lymphocytes. All of the test-stains showed obviously positive antigen activities which coincided with blood group of the sources. The experiments of the test-stains treated with trypsin revealed that the treated stains showed a similar agglutin-ability to that of the treated red cells. From the results, it is concluded that the blood components have M or N antigen activity which is a little lower than the red cells.抄録全体を表示PDF形式でダウンロード (311K) -
MAKOTO TAMAI1973 年 109 巻 1 号 p. 7-11
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーIn chloralose-anesthetized, immobilized cats, evoked responses in the superior colliculus by the electrical stimulation of the ipsilateral cortex were studied. Systematic electrical stimulation of the hemisphere by the silver ball bipolar electrodes evoked negative-positive or positive field potentials in the stratum opticum of the superior colliculus. The effective sites on the cerebral cortex were found to be the posterior sigmoid, dorsal part of the coronal, the anterior part of the anterior suprasylvian gyri (somatosensory areas) as well as other sensory cortices (acoustic and visual areas). Electrical stimulation of the somatosensory cortex elicited field potentials in the ipsilateral superior colliculus which showed a constant sequence of wave form and amplitude. They increased in amplitude, reached a maximum and then decreased as the electrode was advanced deeper into this organ. The depth at which a maximal response was recorded was in the stratum album intermediale. This was confirmed by the histological examination with the electrolytic lesion technique. These results were compared with those reported in our previous paper (Tamai and Ogawa 1972).抄録全体を表示PDF形式でダウンロード (254K) -
KEIYA TADA, KATSUHIRO SUGITA, KEN FUJITANI, TSUTOMU UESAKAI, GORO TAKA ...1973 年 109 巻 1 号 p. 13-18
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA three-year-old girl with clinical pictures suggestive of Leigh's encephalomyelopathy was described. The patient showed a persistent elevation of pyruvate and lactate in blood and an occasional increase in serum alanine. Serum alanine was found to increase in proportion to blood pyruvate level. Pyruvate level in the cerebrospinal fluid was also elevated. In liver tissue obtained by biopsy there were decrease in the activity of pyruvate carboxylase and normal activity of pyruvate decarboxylase. The cultured skin fibroblasts revealed no significant activity of pyruvate carboxylase in either the patient or controls and no difference in the activity of pyruvate decarboxylase between the patient and controls.抄録全体を表示PDF形式でダウンロード (296K) -
HIROSHI KURIHARA, ALFRED GREGORY, PHILIPPE DEWAILLY, ROGER BOUCHER, JA ...1973 年 109 巻 1 号 p. 19-27
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーPlasma angiotension I converting enzyme activity (PCEA), plasma renin activity (PRA) and plasma renin substrate (PRS) were measured in rabbits with experimental renal hypertension and under various sodium intakes. Hypertension was produced by constriction of one renal artery, with or without contralateral nephrectomy. PCEA remained unchanged up to 6 to 7 weeks after clipping. High PRA and hematocrit were observed in rabbits with a clipped renal artery and an intact contralateral kidney, but not in those with a clipped renal artery and contralateral kidney removed. PCEA was independent of the sodium intake or depletion. From these results, it seems that there is no significant role of PCEA in the pathogenesis of experimental renal hypertension in rabbits, and PCEA does not appear to be affected by the same stimuli which are known for the control of PRA.抄録全体を表示PDF形式でダウンロード (473K) -
NOBUAKI SASANO, HYOTARO KUNII, SHIGEO HONMA, MINEKO FUKUSHIMA1973 年 109 巻 1 号 p. 29-39
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーTwo cases of uterine carcinoma concomitant with choriocarcinoma in the same tumor were reported. The basic pattern was undifferentiated squamous-cell carcinoma of the cervix in the first case and well differentiated adenocarcinoma of the corpus in the second. Both cases had a histological transition from usual patterns to choriocarcinoma in certain areas of the tumor. Urinary gonadotropin was assayed in the first case and the level of hexose was close to that in pituitary FSH rather than pituitary LH and HCG.抄録全体を表示PDF形式でダウンロード (3921K) -
ICHIRO MATSUDA, SHINICHIRO ARASHIMA, MICHIYA ANAKURA, AYAKO EGE, ISAMU ...1973 年 109 巻 1 号 p. 41-48
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA 4 2/12-year-old girl with fucosidosis was described who is a first documented case in Japan. It was noted that α-L-fucosidase activity was completely absent in liver tissue, white blood cells, cultured skin and fibroblasts. In the liver tissue obtained by biopsy, fucose-rich glycolipids as well as glycoprotein was found to be markedly increased, whereas the amounts of acid mucopolysaecharide estimated by the uronic acid content were only slightly elevated.抄録全体を表示PDF形式でダウンロード (2433K) -
ICHIRO MATSUDA, NAOYOSHI SHIDA, KEIKO YAMAMOTO, YASUO TAKEKOSHI1973 年 109 巻 1 号 p. 49-55
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA case is reported of a 13-year-old Japanese boy with idiopathic dwarfism and mild acidosis which was shown to be resulted not from decreased ammonium and titratable acid excretion but from bicarbonate reabsorption. The possibility that growth retardation modifies the renal regulation of acid-base balance was discussed.抄録全体を表示PDF形式でダウンロード (330K) -
TOSHIO KUDO, AKIRA WAKUI, JUN-ICHI KIKKAWA, TSUNEJI ICHIKAWA, TATUO SA ...1973 年 109 巻 1 号 p. 57-67
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーFatty acid composition in the tumor-bearing host liver was analyzed and the following results were obtained: 1) In normal liver, C16:0 was rich in cholesterol ester. The percentage of C18:0 was higher in phospholipid than that in cholesterol ester. The percentage of C18:0 in triglyceride+NEFA fraction was smaller than that in cholesterol ester. C18:1 was abundant in triglyceride+NEFA and the percentage of C18:2 was also high in triglyceride+NEFA. As compared with the normal liver, the fatty acid composition in Ehrlich ascites carcinoma-bearing host liver at 6 days after inoculation was almost at the same level as in the normal liver. On the other hand, the fatty acid composition at 12 and 18 days after inoculation was considerably different from that of normal liver. 2) As regards the fluctuation of main fatty acids in Ehrlich ascites carcinoma-bearing mouse liver during tumor growth, the percentage of C18:0 increased in every fraction except for cholesterol ester in mitochondrial fraction. C18:2 showed a decrease except in two fractions, that is, cholesterol ester in the supernatant and phospholipid in the microsomal fraction. C20:4 of phospholipid in both mitochondrial and microsomal fractions increased gradually.抄録全体を表示PDF形式でダウンロード (505K) -
NAOFUMI IWATSUKI1973 年 109 巻 1 号 p. 69-75
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA direct inotropic effect of CT 1341, a new steroid intravenous anesthetic, upon the myocardium was studied in isolated heart muscles of dogs by measurements of force-velocity relation. CT 1341 at the concentrations over 0.139ml/100ml caused a dose-dependent leftward shift of the force-velocity curve. The maximum velocity of muscle shortening at zero load (Vmax) was decreased progressively with increasing concentration of CT 1341. The values of Vmax at the concentrations of 0.139ml/100ml, 0.279mg/100ml and 0.556ml/100ml were 94.2%, 86.5% and 67.9% of the control, respectively. Peak force, maximum rate of force development and time to peak force during isometric contraction also showed a dose-dependent decrease. Isotonic net shortening, power and work on the heart muscle were decreased dose-dependently at any given load levels. These results suggest that CT 1341 exerts a direct negative inotropic effect on the myocardium. However, the values of Vmax were 98.6% and 94.2% of the control at the concentrations of 0.056ml/100ml and 0.139ml/100ml, which were considered approximately to be the range of blood concentration at the clinically recommended induction doses (0.04-0.1ml/kg). Therefore, the negative inotropic effect of CT 1341 upon the myocardium seems to be minor when it is used within the range of these doses.抄録全体を表示PDF形式でダウンロード (301K) -
KEISHIRO KARITA, SEISHO ITO, KYOJI TASAKI1973 年 109 巻 1 号 p. 77-84
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe electroretinogram of the isolated eye of the gastropod (Haliotis discus) was studied with penetrating microelectrodes. The response recorded from the retinal surface with respect to the back of the eye was a slow negative potential change, but the response from the deeper layer was positive in polarity, indicating a depolarization of the distal part of the receptor cells. The electroretinogram of the dark adapted retina was a monophasic potential which had a smooth rising phase, but that of the light adapted retina was more complex in form, having an inflection which suggests the existence of the two responses in this simple retina of the abalone. Experiment of strong light adaptation and application of hypertonic KCl or ether vapor revealed that the electroretinogram consists of fast and slow components, and that the slow component is more susceptible to light adaptation and chemicals. Since one of the two responses originates undoubtedly from the receptor cells, the other origin was concluded to be the supporting cells, the response of which may be generated by some metabolic processes between the receptor and supporting cells.抄録全体を表示PDF形式でダウンロード (2546K) -
TAEKO HIROSE, RYOZO HIGASHI, HIROYUKI IKEDA, KAZUNORI TAMURA, TATUZI S ...1973 年 109 巻 1 号 p. 85-88
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーConscious dogs were infused intravenously with ethanol solution in a dose of 0.7-1.0g/kg. Before and after the ethanol infusion, the adrenal venous blood samples were collected and analyzed for adrenaline and noradrenaline fluorimetrically. In dogs infused with ethanol in a dose of 0.7g/kg, the blood ethanol concentration was elevated to 70-120mg/100ml. The animals became depressed but did not sleep. No change in adrenaline and noradrenaline secretion of the adrenal gland was observed. In dogs infused with 1.0g/kg of ethanol, the blood ethanol concentration just after the end of the infusion was 191-241mg/100ml. The animals lay down and slept deeply. In 3 out of 5 dogs the adrenal medullary secretion rates remained unaltered and in the other 2 dogs a definite increase in adrenaline and noradrenaline secretion was observed after the administration of ethanol.抄録全体を表示PDF形式でダウンロード (249K) -
TOMIHISA FUNYU, KAZUMI OHNO, YASUO SHIRAIWA, TADASHI SUZUKI1973 年 109 巻 1 号 p. 89-94
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA new operative technique was devised for the undilatable strictures of bulbous and membranous urethra. The principle of our method is to approach the stenotic urethra from lateral portion of urethral bulb by pushing out the bulb (either to the right or to the left) without sectioning. Eleven patients were subjected to the operation and short-term results after operation were favorable.抄録全体を表示PDF形式でダウンロード (340K) -
SHIGETOSHI CHIBA, KOROKU HASHIMOTO1973 年 109 巻 1 号 p. 95-96
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーDirect perfusion of the sinus node artery under a constant pressure of 100mm Hg was arranged in eight canine hearts in situ. The administration of MnCl2, at doses from 10 μg to 10mg into the sinus node artery induced a longlasting negative chronotropic response. MnCl, blocked the effects of caffeine which induced double peaked positive chronotropic responses, i.e., initial rapid acceleration of sinus rate followed by slow and long-lasting acceleration. The initial acceleration was resistant to propranolol or tetrodotoxin, but completely blocked by MnCl2. Thus, the initial positive chronotropic response to caffeine may be probably ascribed to its essential effect of the movement of Ca ions on the SA nodal pacemaker cell.抄録全体を表示PDF形式でダウンロード (93K)
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