巻号一覧
111 巻 (1973)
- 4 号 p. 309-
- 3 号 p. 203-
- 2 号 p. 101-
- 1 号 p. 1-
111 巻, 4 号
選択された号の論文の12件中1～12を表示しています
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Identification of the Bursa-dependent and Thymusdependent Areas in the Tonsilla Caecalis of ChickensHAJIME HOSHI, Tom MORI1973 年 111 巻 4 号 p. 309-322
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーIn this report, on the basis of the difference in lymphocytic make-up, the lymphatic tissue of the tonsilla caecalis was divided into two parts, the mid and deep portion of the lamina propria and its superficial portion which was referred to as a subepithelial zone. In the former there were accumulated small lymphocytes, while in the latter lymphocytes in various sizes, small to large, and cells of plasmocytic series. The germinal centers always appeared in the mid and deep portion and never in the subepithelial zone. Chickens which were bursectomized and X-irradiated at hatching showed a marked depletion of lymphocytes in the subepithelial zone while an increasing accumulation of small lymphocytes was persistent in the mid and deep portion. On the other hand, in chickens which received repeated X-irradiation of the thymus, lymphocyte depletion was striking in the mid and deep portion but not in the subepithelial zone. In both groups of treated chickens the germinal centers were markedly decreased in number or essentially lacking. In the bursectomized-irradiated chickens, foci of reticular cell aggregation usually occurred in the mid and deep portion and were deemed as an incomplete form of the germinal center. It was concluded that in the tonsilla caecalis the bursa-dependent area was the subepithelial zone and the thymus-dependent area was the mid and deep portion of the lamina propria, Possible relation to the germinal center development of three factors, i.e. the formation of the focus of reticular cell aggregation in the thymusdependent area, the accumulation of bursa-derived lymphoid cells and a certain thymus-dependent factor, was discussed.抄録全体を表示PDF形式でダウンロード (6295K) -
AKIRA SAITO1973 年 111 巻 4 号 p. 323-345
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe author has statistically studied the acidity of gastric juice obtained from 1, 100 cases of gastric cancer, 29 cases of gastric polyps, one case of gastric sarcoma, one case of gastric myoma, 5 cases of duodenal cancer, 570 cases of gastric ulcer, 90 cases of gastroduodenal ulcer and 505 cases of duodenal ulcer, and the following conclusions were obtained. (1) In neoplasm, anacidity and hypoacidity appeared in an overwhelming majority of cases; 84.4% of gastric cancer, 89.6% of gastric polyps and 100% of duodenal cancer were of anacidity and hypoacidity. On the contrary, in ulcer, hyperacidity and super-hyperacidity were quite often found; 41.8% of gastric ulcer, 69.7% of duodenal ulcer and 65.5% of gastroduodenal ulcer cases were found to have hyperacidity or super-hyperacitity. (2) Of gastric cancer 60.5% were found to have anacidity during the entire investigation. Some of gastric cancer patients who had once normoacidity or hyperacidity showed anacidity or hypoacidity later and vice versa. It was found that almost all of the gastric cancer patients had anacidity at some stage. (3) 58.6% of gastric ulcer, 85.1% of duodenal ulcer and 86.8% of gastroduodenal ulcer cases showed hyperacidity or super-hyperacidity all the time. On the contrary, 7.3% of gstric ulcer, 2.8% of duodenal ulcer and 1.5% of gastroduodenal ulcer cases showed hypoacidity or anacidity. It should be noted that the number of ulcer patients who had hypoacidity or anacidity could be found to be less if the gastric juice examination was repeated frequently. (4) It has been demonstrated that the gastric secretion is controlled by the autonomic nervous system as other clinical signs and symptoms. In an individual with sympathicotonic type of constitution, anacidity or hypoacidity with clinical signs and symptoms of a sympathicotonic type appears, and a parasympathicotonic type of constitution shows hyperacidity or super-hyperacidity with clinical signs and symptoms of a parasympathicotonic type.抄録全体を表示PDF形式でダウンロード (1172K) -
Preparation of Cell Lysate for Separation of Polyoma DNA from Cellular DNA by Sedimentation VelocityKENTARO TOH, TOMIZO OKUYAMA, MASAKATSU IMAMURA, KOKICHI KIKUCHI1973 年 111 巻 4 号 p. 347-351
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA simple procedure was devised to prepare the cell lysate for clear separation of viral and cellular DNA by sedimentation velocity allowing simultaneous observation of changes of both DNAs. This method was also useful to detect grades of fragmentation of DNA due to treatment of cells with drugs or to physical influences.抄録全体を表示PDF形式でダウンロード (256K) -
KATSUHIRO WATANABE, SHIRO TOMINAGA, TAKASHI NAKAMURA1973 年 111 巻 4 号 p. 353-360
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe activities of crude adenosine and AMP aminohydrolases isolated from skeletal muscle (apparent Km: 68 and 72 μM, respectively), and crude cardiac adenosine aminohydrolase (Km: 48) are spectrophotometrically determined in the presence of some chemical factors. The activity of cardiac AMP aminohydrolase is practically negligible. We apply a simple assay system, which consists of 1.5 ml of 0.05M Tris (hydroxymethyl)-aminomethane-HCl buffer (pH 7.38), 1 ml of substrate solution (10-500 μM of adenosine or AMP, final concentration), and solution of each chemical factor, the concentration of which is assumed to be those in the skeletal muscle during ischemia or contractions. Among such factors, ammonia (0.5-5mM, final concentration), lactate (50-200mM) and phosphoric acid (PO4---: 25-50 mEq/liter) depress in this order, and potassium chloride (K+: 150-250 mEq/liter) activates these enzymes. Bubbling of carbon dioxide and nitrogen gases depresses the activities markedly and slightly, respectively. It is unclear, however, whether carbon dioxide itself has inhibitory action, because there is marked decrease in pH of the medium when its effect was obvious. Bubbling oxygen gas induces an activation of the enzymes. The enzyme activities show no detectable changes in near physiological range of pH (7.0-7.8). Changes in the factors, which occur in the skeletal muscle during ischemia or contractions, induce depression of the enzyme activities except pH. The disputable reports on the deamination of AMP are reviewed and discussed.抄録全体を表示PDF形式でダウンロード (479K) -
MASANA OGATA, JUNKO MIZUGAKI1973 年 111 巻 4 号 p. 361-364
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe single radial diffusion of human erythrocyte catalase against anti-crystalline beef liver catalase rabbit serum can be applied as a screening method of hypocatalasemia.抄録全体を表示PDF形式でダウンロード (591K) -
MASAFUMI SHIRAI, SHOTARO MATSUDA, KENSUKE OZU1973 年 111 巻 4 号 p. 365-369
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe rate of the appearance of F-body in the spermatozoa of oligospermic patients with sterility was compared to that of normal subjects. A five-minute staining method, using a 0.0025% quinacrine mustard solution, was the procedure. The rate of appearance of the F-body in normal males was 42.4% in average, while it was only 9.3% in oligospermia. As the number of spermatozoa decreases, the rate of appearance of F-body appears to fall.抄録全体を表示PDF形式でダウンロード (880K) -
KAZUKUNI YAMASHITA, TAKESHI SHIMIZU, MASAHIRO MIENO, KUNIHIKO KAWAO1973 年 111 巻 4 号 p. 371-375
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーAdult male dogs were injected into the third ventricle (3 rd V) with graded doses of cateeholamines and indoleamines, and changes in secretion of testicular 17-oxosteroids by the testis were investigated for up to 2-4 hr after the injection. The secretion of testicular 17-oxosteroids was not affected by intraventricular treatment with 2, 5 and 10 μg of dopamine but stimulated slightly with 50 μg. The response was transient and occurred for up to 90min after the injection. Intraventricular injection of 50 and 100 μg of noradrenaline or adrenaline had no stimulatory effect nor did it significantly alter the secretion of 17-oxosteroids by the testis for up to 120min after the injection. Furthermore, serotonin and melatonin, given into the 3 rd V with doses of 5 and 50 μg, caused little or no secretion of testicular 17-oxosteroids.抄録全体を表示PDF形式でダウンロード (277K) -
KAORU SAGISAKA, KAZUO TOKIWA1973 年 111 巻 4 号 p. 377-385
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーRabbits were immunized with one of the following four kinds of red cells; M red cells treated with 0.1% trypsin for 60 minutes, N red cells treated likewise for 90 minutes, and non-treated M and N red cells. Trypsin-treated red cells were injected three times a week for five weeks, and non-treated red cells daily for 35 to 45 days. All rabbits produced agglutinins to the four kinds of red cells. As for antisera to treated M or N red cells, titers against treated M and N (mostly 1:2, 560 to 1:5, 120) were much higher than those against non-treated M and N (1:200 to 1:2, 560). When the antisera to treated red cells were adsorbed with non-treated M or N red cells, agglutinins to the adsorbing red cells decreased, but those to treated M and N red cells changed scarcely. On the contrary, treated M and N red cells adsorbed well agglutinins to both treated and non-treated M and N red cells. Adsorptions of the antisera to non-treated red cells showed almost similar results to those of the antisera to treated ones. But repeated adsorptions with non-treated red cells indicated the decrease of agglutinins to treated red cells. From these results, it seemed unlikely that N antigenicity developed in M red cells treated with the enzyme, even though the M red cells were able to react with specific anti-N serum.抄録全体を表示PDF形式でダウンロード (449K) -
KAZUKUNI YAMASHITA, TAKESHI SHIMIZU, MASAHIRO MIENO, KUNIHIKO KAWAO1973 年 111 巻 4 号 p. 387-391
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーThe effect of chronic intraventricular treatment with melatonin on release of interstitial cell-stimulating hormone (ICSH) from the pituitary was studied in adult male dogs. A single intraventricular administration of melatonin at the doses of 1 and 10mg caused a reduction of the pituitary ICSH activity 10 days after the injection. Concomitantly, there was depletion of plasma ICSH activity. Control injection of isotonic saline solution or 1.6% alcohol-isotonic saline solution did not significantly alter the ICSH activity in the pituitary and the plasma of intact animals. The results are in accord with the hypothesis that melatonin exerts an inhibitory action on the release of pituitary ICSH.抄録全体を表示PDF形式でダウンロード (302K) -
HISAO SUZUKI, MASATUGU TAKAHASHI1973 年 111 巻 4 号 p. 393-403
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーA number of lateral geniculate neurons are excited by a volley delivered to either one or the other optic nerve and the resulting excitation is inhibited by stimuli to the other optic nerve. In this report, the distribution of the binocularly interacting (BI) neurons in the three cell laminae A, Al and B of the geniculate nucleus was studied in the cat anesthetized with a chloraloseurethane mixture. Unit discharges of the geniculate neurons were explored with stainless-steel microelectrodes. The neuron responded with an action potential to a volley to either one of the two optic nerves. In some of the neurons, a conditioning volley delivered to the optic nerve inhibited spike generation of the neuron excited by the test volley. The conditioning volley itself evoked no spike in the neuron but produced inhibition. This identified it as a BI neuron. The recording sites of the geniculate neurons were marked by electrolytic deposition of iron and the marking sites were identified by the use of the Prussian blue reaction. Of a total of 169 geniculate neurons thus identified, 42% of the neurons situated in lamina A, 84% of the neurons in Al and 47% in B showed a binocular inhibitory interaction.抄録全体を表示PDF形式でダウンロード (1558K) -
SHIGETOSHI CHIBA, KEISUKE SATOH, KOROKU HASHIMOTO1973 年 111 巻 4 号 p. 405-406
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーMnCl2 induced negative dromotropic effect on the AV node of dogs in situ. At a dose level above 10mg, a transient AV block was observed. The injection of 1-3mg of MnCl2 suppressed the acceleration of AV nodal rhythm, which was induced by administration of 1 μg of norepinephrine.抄録全体を表示PDF形式でダウンロード (627K) -
YOSHITADA TAKING, MASUICHI TAKINO1973 年 111 巻 4 号 p. 407-408
発行日: 1973年
公開日: 2008/11/28
ジャーナル フリーEffects on rheumatoid arthritis of three pteridines contained in fluorescent bacteria, i.e., 6-hydroxyethyl-2. 4. 7-trioxo-8-D-ribityl-pteridine, 8-D-ribityl-trioxopteridine, and 8-D-ribityl-6-methyl-2. 4. 7-trioxopteridine, and of luciopterin (8-methyl-2. 4. 7-trioxo-pteridine) taken from firefly were studied in 20 patients with rheumatoid arthritis. All the pteridines were found to exert a favorable effect upon the ailment. The first pteridine was the most effective, followed by the second and the third in decreasing order of effectiveness.抄録全体を表示PDF形式でダウンロード (136K)
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