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Volume 57 (1952 - 195･･･
- Issue 4 Pages 299-
- Issue 2-3 Pages 101-
- Issue 1 Pages 1-
Volume 57, Issue 2-3
Displaying 1-27 of 27 articles from this issue
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The 3rd Report The Blood and Plasma Catalase Content in Blood DiseasesSyoiti Yamagata, Sukehiko Seino1953 Volume 57 Issue 2-3 Pages 101-107
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSFrom these experiments it can be concluded as follows: the blood catalase content changes in the close connection with erythrocytes and hemoglobin, but the plasma catalase content is influenced to a great extent not only by the hemopoietic function, but also by the hemolysis in a living body and the function of the spleen.View full abstractDownload PDF (386K) -
II. Hydrolysis TestMasabumi Yamasaki1953 Volume 57 Issue 2-3 Pages 108
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Toshihiko Oikawa1953 Volume 57 Issue 2-3 Pages 109-117
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe cone- and rod-responses to various spectral lights were studied-by means of the electro-stimulation method at various parts of the human retina.
1. The cone-curves were found much higher than the rod-curves in every case.
2. The cone-curves for red light showed a maximum at 1 sec. in the central parts of the retina, but its crest began to shift toward a longer time at 30° from the fovea. It was pointed out that the shift was closely connected with the alteration of hue from red to orange.
No such shift could be observed in the curves for yellow and blue, whose maxima were always located at 1.5 and 3 sec. respectively.
3. The magnitude of the rod-response was greatest at the 20° periphery, where the population density of rods was greatest.
4. The response magnitudes of the photopic receptors were represented as a function of distance from the fovea and compared with the distribution curves for color-sensitivity by Wentworth. Agreement was not satisfactory, but the curves representing the ratio of the coneresponse to the rod-response showed more satisfactory agreement with Wentworth's color-sensitivity curves. This fact suggests that some interaction takes place between cones and rods.
Prof. K. Motokawa furnished guidance and helpful criticism, for which I express here hearty thanks.View full abstractDownload PDF (461K) -
Preliminary ReportMasabumi Yamasaki1953 Volume 57 Issue 2-3 Pages 118
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Fourth Report Influence of Ingestion of Water on the Intragastric TemperatureHisayuki Masuda1953 Volume 57 Issue 2-3 Pages 119-127
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSI studied the changes in the intragastric temperature by introducing water into the stomach of healthy adults in comparison with those in the model experiments. Varying both temperature and volume of the water to be introduced, the following facts were confirmed.
1. The intragastric temperature abruptly drops or rises according to the temperature of the introduced water, but it does not reach the latter.
2. The recovery thereafter is expressed by an exponential function.
3. The time for recovery is practically decided by the time when the intragastric temperature returns within 0.1°C from the initial temperature.
4. The temperature of the introduced water essentially determines the change in the intragastric temperature immediately after the introduction of water and the volume of it governs the type of the recovery thereafter.
5. Those which deviate from the above cited relation between the intragastric temperature and temperature or volume of the introduced water seem to be due to the responses of the stomach itself under the control of the autonomic nervous system.View full abstractDownload PDF (429K) -
Fumio Chiba1953 Volume 57 Issue 2-3 Pages 128
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Fifth Report Response of the Intragastric Temperature to Various DrugsHisayuki Masuda, Mitsuo Ohara, Shigeaki Katsura1953 Volume 57 Issue 2-3 Pages 129-135
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSResponse of. the intragastric temperature of healthy men to subcutaneous injection of histamine, adrenaline, pilocarpine and atropine was studied simultaneously with those of the axillary temperature, pulse rate, blood pressure and gastric juice; and the following facts were confirmed.
1. The intragastric temperature drops by the four drugs.
2. The drop by histamine is transient contrary to those by adrenaline and pilocarpine and the drop by atropine is preceded by a slight rise.
3. The maximum drop is large by histamine and pilocarpine and small by adrenaline and atropine.
4. Onset of the drop is more rapid by histamine than by pilocarpine and adrenaline and is slowest by atropine.
5. Combination of the maximum drop and the time for reaching it, is different by the four drugs.
6. Change in the axillary temperature is generally parallel with that in the intragastric.
7. Change in the pulse rate is in intimate relation with that in the intragastric temperature. Blood flow is one of the most important factors in the change in the intragastric temperature.
8. By histamine and pilocarpine which strongly stimulate the gastric secretion, the intragastric temperature is intensely lowered.View full abstractDownload PDF (354K) -
III. Test by Pyronin-Methylgreen StainingMasabumi Yamasaki, Tsunetake Oikawa1953 Volume 57 Issue 2-3 Pages 136
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Sixth Report Response of the Intragastric Temperature to Various Drugs (Part II)Hisayuki Masuda, Mitsuo Ohara, Shieeaki Katsura1953 Volume 57 Issue 2-3 Pages 137-143
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSResponse of the intragastric temperature of healthy men to subcutaneous injection of benzylimidazoline, prostigmine and histamine and to intravenous injection of benzylimidazoline and tetraethylammonium bromide was studied, simultaneously with those of the pulse rate, blood pressure and gastric juice; and the following facts were confirmed.
1. The intragastric temperature drops by benzylimidazoline, tetraethylammonium bromide and histamine, and rises by prostigmine.
2. The drop by benzylimidazoline is generally proportional to the injected dosis but the type is different by the mode of injection-by the subcutaneous injection the drop gradually increases and by the intravenous it rapidly appears and recovers.
3. The drop by tetraethylammonium bromide is approximately the same as that by intravenously injected benzylimidazoline.
4. The drop by histamine is greatest and both the onset and the recovery are most rapid.
5. The rise by prostigmine is preceded by a certain period when no significant change is observed.
6. The change in the intragastric temperature is in intimate relation with the blood flow and is determined by an aggregation of the pulse rate and blood pressure.
7. The change in the intragastric temperature is not related with that in the gastric free acidity.View full abstractDownload PDF (342K) -
Susumu Iijima, Tomonori Kanazawa1953 Volume 57 Issue 2-3 Pages 144
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Rokuro Yabuki1953 Volume 57 Issue 2-3 Pages 145-155
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSSensory terminations of aortic nerve acting reducingly on blood pressure are in the fetal life dispersed over a large area centered on the lower edge of arcus aortae i.e. over the entire of arcus aortae, aorta ascendens, the emergent parts of truncus brachiocephalicus and a. carotis comm. sin. as well as a. pulmonalis. Their development, however, is more remarkable in the earlier half of the fetal life, coming into degenerative change in the later stage, especially in a. pulmonalis.
Sensory terminations of aortic nerve found in arcus aortae and aorta ascendens, widely unlike their counterpart in adult, are formed along the smooth muscle fibres of the media and of uncomparably simpler formation. But in quantity, they surpass by far such terminations in adult. Consequently, these cannot be looked upon as corresponding to the Type I terminations in adult.
As almost no blood vessel is found penetrating the media, no sensory terminations corresponding to the Type II terminations in adult are formed in fetal stage. They are likely to be formed gradually after birth.
Sensory terminations found in the incipient parts of truncus brachio-cephalicus and a. carotis comm. sin. of human embryo pass from the externa into the media and sometimes even the intima and their terminal formation is similar to those seen in aorta. Consequently, they must undoubtedly have their origin in aortic nerve.
In the pulmonary artery also is observed the existence of sensory terminations of similar conformation. They are discovered in a large quantity in 4th month embryo, but in 8th month embryo they are found degenerated to a large extent and remaining as a few simple branched terminations in the externa.
The above described terminations of aortic nerve in embryo are believed to change over into the Type I and Type II terminations after birth. The process of transition, I presume, consists in that the terminations in the media so gradually degenerate and disappear, that the majority of their stem fibres retrocedes to be only limited to the externa of the lower edge of arcus aortae, and then the tips of stem fibres newly develop peculiar terminations coming under the Types I and II.
The reason why the sensory fibres of aortic nerve extended over a large area of major arteries terminate in the media thereof is thought to lie in the fact that the circulation activity in the embryo has to keep up incessant and extremely flexible adaptation to the fluctuation in the flow of blood in the maternal arteries.View full abstractDownload PDF (3000K) -
Masao Ohgaki1953 Volume 57 Issue 2-3 Pages 157-167
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe epithelium of facies inferior linguae mostly is much thinner than that of dorsum linguae, the formation of the papillae being correspondingly weaker, especially as the rear parts are approached. But, in the marginal parts the epithelium is thicker, and large papillae provided with secondary papillae or especially with taste-buds are observable accordingly. As the epithelium of the vicinity of.the median line is thick too, comparatively large papillae or taste-buds.papillae can be seen also here. However, all of the papillae seen in facies inferior linguae even do not admit protrusion of epithelium over the surface, in contradistinction to the papillae in dorsum linguae, and the epithelial surface is kept always smooth and even. The epithelium of the plica fimbraiata is thinnest and the papillae are of poorest development, vet a very few of small taste-buds are provable.
The plexus formed in the subepithelial layer consists of thick sensory and fine vegetative fibres, the latter finally passing into the Stohr's terminalreticulum. The sensory fibres are of much weaker development than in dorsum linguae, but are rather well-developed in accordance with the development of the papillae. So, the development of sensory terminations in marginal parts and the vicinity of the median line is considerable.
The sensory terminations in facies inferior linguae may be divided into simple unbranched and branched terminations, complex branched terminations, non-capsulated and capsulated glomerular terminations, and special terminations for taste-buds.
Of the sensory terminations found in the large papillae without tastebuds, glomerular terminations, especially capsulated ones, and plexuslike terminations may be mentioned as of special interest, though they are much lower numerically than in dorsum linguae. The former consist of thick sensory fibres, which after losing the myelin, show peculiar change in size and a winding course and terminate in simple glomerular arrangement. They are in general capsulated and provided with numerous special nuclei in the inner bulb. Plexus-like terminations are composed of two or three thick sensory fibres dividing into two or three branches, which show the irregular plexus-like terminal arrangement.
The development of sensory fibres for the samil papillae is very weak in comparison with the above, and many of them even lack sensory fibres. And in small papillae where sensory fibres enter, their terminal mode is simple, mostly represented by unbranched or simple branched terminations. However, there are found not rarely corpusclar, especially simple noncapsulated glomerular terminations, and two or three such bodies can be found in one small papilla, though in a small quantity.
In the large taste-bud papillae, plexus is formed at the base, and the sensory fibres penetrate the papillae, being accompanied by vegetative fibres, mostly to pass into simple arborized or undetermined terminations, but partly into corpusclar, especially into non-capsulated glomerular terminations. These bodies are frequently formed just beneath the tastebuds, sometimes sending out intra- and extragemmal fibres.
The small taste-bud papillae are very often devoid of sensory fibres, but sometimes sensory fibres run into them with vegetative fibres, to pass into non-capsulated glomerular terminations in the tip of the papillae, more rarely sending out intragernmal fibres.
As detailed above, since the morphological development of sensory fibres for the taste-buds found in facies inferior linguae is incomparably weaker than in the papillae circumvallatae, it may be assumed that they are also functionally much degenerated ones.View full abstractDownload PDF (2917K) -
Shinichi Okano1953 Volume 57 Issue 2-3 Pages 169-179
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThere is no essential histological difference between the motor end plates in the tongue of dog and that of man. In the former, as well in the latter, the Boeke's accessory fibres are not of sympathetic but of motor nature. In the canine tongue, few if any muscle spindles are found.
The nerve cells found in many places on the nerve bundles running through the tongue muscles and gland parenchyma, the Remak's hemiganglion cells in the basal plexus in the foliate and cirumvallate papillae and the sporadically occurring nerve cells in tela sumbucosa are all small and degenerative, but are multipolar and must be of sympathetic nature. The termination of vegetative fibres in dog tongue is also represented by the terminalreticulum.
The filiform papillae are much smaller in scale than by man, showing low cylindrical form containing 2 or 3 secondary papillae, with very weak cornified surface of epithelium. The sensory fibres thereto are correspondingly very few in number, and the terminations are in general of simple unbranched or branched type consisting of medium or small size fibres, but frequently of larger fibres showing change of size. No intraepithelial fibres are found to exist. Corpusclar terminations as seen in man also are lacking.
The fungiform papillae are small at the fore part of the tongue but larger at the hinder part, with secondary papillae. In the epithelium taste buds are often observed. The innervation is weak in the fore part, but as we go backward, the nerves become better developed, with frequent formation of basal plexus at the base. The sensory fibres originating in it run into the papillae, to pass into simple branched and unbranched or more complex plexuslike terminations. But also here, no corpuslcar terminations may be seen. But as the epithelium is covered by the corneous plate, formation of intraepithelial fibres may be observed, though in a weak development. The development of gustatory fibres to the taste buds is also poor, most of them being out of direct supply of intra- and extragemmal fibres.
In the canine foliate and circumvallate papillae, many taste buds exist not only in the epithelium facing the grooves but also in that facing the mouth cavity. But in the epithelium of the wall surrounding the circumvallate papillae, the existence of taste buds is very limited. At the base of these two kinds of papillae, conspicuous formation of basal plexus is seen, and the sensory fibres originating in it are better developed than in filiform and fungiform papillae, forming terminations of various forms under the epithelium. Simple unbranched terminations are little in number, branched terminations being prevalent. Branched terminations are further divided into simple and complex forms, the latter again into arborized and plexus-like terminations showing change in size and peculiar winding course of the fibres.
The development of sensory fibres to the taste buds in these papillae is rather good, but glomerular terminations observable in man cannot be found, only simple quasi-glomerular bodies being formed rarely in the foliate papillae. However, similarly to the human counterparts, looplike, plexus-like and other simple branched terminations are not lacking under the taste buds here. Intra- and extragemmal fibres often run into or around the taste buds, but these are generally unbranched, ending sharply, never in knob-like nor lamellar bodies. As many of these taste buds are observed without any direct supply of sensory fibres, it may be concluded that the development of the gustatory fibres is much inferior in dog tongue than by human being.View full abstractDownload PDF (5194K) -
(Pyruvaldehyde or Pyruvic Aldehyde) from Human Milk, Parts I & II 264th Report of the Peroxidase Reaction (211th Human Milk Study)Hiroshi Wako1953 Volume 57 Issue 2-3 Pages 181-190
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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(Pyruvaldehyde or Pyruvic Aldehyde) from Human Milk Part III Identification of acetaldehyde and methyl glyoxal from human milk by paper partition chromatography 265th Report of the Peroxidase ReactionHiroshi Wako1953 Volume 57 Issue 2-3 Pages 191-197
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSHitherto it has been accepted without experimental evidence that in athiaminosis pyruvic acid would occur in human milk, while methyl glyoxal or pyruvaldehyde would never occur in it, especially as this substance has generally been discarded since the Embden-Meyerhof theory came into favor.
But my own actual experiment has shown the following results:
The occurrence of acetaldehyde and methyl glyoxal in human milk was assured by paper chromatography. Pyruvic acid was not identified in human milk. In Parts I and II of this treatise, I stated that I had isolated with success acetaldehyde and methyl glyoxal from human milk. Pyruvic acid was never identified. These results were also ascertained by paper partition chromatography. (Cf. Summary for Parts I & II.)
Remarks. Methyl glyoxal as an intermediate of normal carbohydrate metabolism has, as has been stated in Introduction of Part I, lost in favor. Not only that, but also it has been considered sometimes as secondarily produced or even an “artifact” due to the instability of such substances as glyceraldehyde, dioxyacetone, diacetyl, acetol or lactic aldehyde, from which (esp. the first) the glyoxal might be produced. But now I firmly believe, on the basis of many Reports on Human Milk Study from our Laboratory, that there is an abnormal and quite a natural course of production of methyl glyoxal which, in normal metabolism, will not occur in an identifiable form or, if at all, occur in a trace.View full abstractDownload PDF (304K) -
Tsuneo Arakawa, Shigeo Wada1953 Volume 57 Issue 2-3 Pages 199-204
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Studies on the Nutrition of Children in the Hirosaki Area (14th Report)Hirozumi Yoshida1953 Volume 57 Issue 2-3 Pages 205-210
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSElectrophoretic analysis of sera was carried out on 21 cases of ‘normal’ children (Group I), 24 cases of children who were apparently healthy, but showed clinical manifestation of nutritional dystrophy to some extent (Group II), and 13 cases of sick children who showed distinct symptoms of nutritional dystrophy (Group III).
For Group I, total protein, albumin, α-globulin, β-globulin and γ-globulin were found in the averages of 6.76±0.19g. per 100cc., 58.7±2.5%, 10.1±0.8%, 12.5±0.8% and 18.6±1.9% respectively; for Group II, 6.83±0.09g. per 100cc., 55.3±2.1%, 9.7±0.9%, 12.7±0.8% and 22.2±1.5% respectively; and for Group III, 6.62±0.63g. per 100cc., 44.0±1.8%, 15.3±1.8%, 15.6±2.4% and 25.0±2.9% respectively.View full abstractDownload PDF (273K) -
Studies on the Nutrition of Children in the Hirosaki Area (15th Report)Hirozurni Yoshida, Yuji Sato1953 Volume 57 Issue 2-3 Pages 211-220
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSElectrophoretic analysis of sera, liver biopsy and Sato's modified bromsulfalein test were carried out simultaneously upon the sick children, from whom were excluded those who were positive to the ordinary bromsulfalein test in which the dye was injected in an amount of 5mg.per kg. of body weight.
According to the relations among electrophoretic pattern, liver biopsy findings and Sato's bromsulfalein test, all the cases examined were divided into 5 groups (Groups A, B, C, D, and E); Groups A and B included the negative cases to Sato's test and Groups C, D and E included the cases positive to Sato's test; histopathological changes in the livers were revealed by a needle biopsy in Groups B, D and E, and not in Groups A and C.
Histopathological changes in the biopsied livers seemed to be more frequently found in the cases positive to Sato's test (Groups C, D, and E) than in the negative cases (Groups A and B), and pathological changes of cytoplasm with fibrosis were found only in the cases with positive response to Sato's test (Group E).
Irrespective of response to Sato's bromsulfalein test and histopathological findings of the biopsied liver, a significant increase in the averages of alpha and beta globulins was found in almost all groups (Groups A, B, C, D and E) and this finding may be partly ascribed to the fact that not a few cases with clear symptoms of nutritional dystrophy were included in the patients subjected to the present investigation.
The ‘abnormal’ electrophoretic pattern characterized by an increase in gamma globulin accompanied by a decrease in albumin was found in the cases which were positive to Sato's test and, in addition, showed histopathological changes of cytoplasm with fibrosis, in the biopsied livers (Group E).
A tendency toward an increase of gamma globulin as well as a decrease of albumin seemed to be very marked in the cases with histopathological changes in the biopsied livers and in those with positive response to Sato's bromsulfalein test as compared with those without pathological changes in the livers or with negative response to Sato's test.View full abstractDownload PDF (448K) -
Takahiko Asano1953 Volume 57 Issue 2-3 Pages 221-225
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Aminopterin demonstrated a notable inhibiting effect upon the growth of the Yoshida sarcoma, especially in cases which received the repeated intraperitoneal injection of 0.05mg. per 100g. body weight. Non-specific changes in the tumor cells after the injection, such as caryorrhexis and vacuolar degeneration were described. These cellular changes were obtained also by subcutaneous injection of the compound.
2. Other 13 folic acid antagonists including Methopterin and folic acid demonstrated neither remarkable cellular changes nor inhibiting effect.
Acknowledgements. The author wishes to express his gratefulness to the Lederle Laboratories, Dr. Sugiura, and the Iatrochemical Institute for supplying the compounds which made this study possible. This study was supported by the “Grant in Aid for Fundamental Scientific Research” of the Ministry of Education.View full abstractDownload PDF (895K) -
Takahiko Asano1953 Volume 57 Issue 2-3 Pages 227-230
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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The 4th Report The Blood and Plasma Catalase Content in Various Experimental AnemiasSyoiti Yamagata, Sukehiko Seino1953 Volume 57 Issue 2-3 Pages 231-238
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSFrom these experiments with various experimental anemias caused by artificial bleeding, phenylhydrazine, saponin, colloidal silver and sodium nitrite, it can be concluded that the blood and plasma catalase is produced in the hemopoietic organs by different process from that of erythrocytes and hemoglobin, while a larger portion of the plasma catalase is produced by the hemolysis in a living body.View full abstractDownload PDF (359K) -
The 5th Report Influence of the Spleen and Reticulo-Endothelial System upon the Blood and Plasma Catalase ContentSyoiti Yamagata, Sukehiko Seino1953 Volume 57 Issue 2-3 Pages 239-247
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSFrom these experiments it can be concluded as follows: the plasma catalase is produced in the RES, especially in the spleen. That is to say, the elevated function of the RES and the spleen causes to increase the plasma catalase content, but the declined function causes the decrease of the plasma catalase content.View full abstractDownload PDF (423K) -
The 6th Report Influence of the Liver upon the Blood and Plasma Catalase ContentSyoiti Yamagata, Sukehiko Seino1953 Volume 57 Issue 2-3 Pages 249-257
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSFrom these experiments it can be concluded as follows : the promoted liver function causes to increase the blood catalase content, but a liver injury caused by chloroform and phosphor causes to lower the blood catalase content, contrary to the increase of the plasma catalase content. Moreover, the combined use of hypertonic glucose solution with vitamin C can check the variation of the blood and plasma catalase content by a liver injury.View full abstractDownload PDF (445K) -
Eigo Kikegawa1953 Volume 57 Issue 2-3 Pages 259-271
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESSThe Calomel-Solid Food-Hot Compress Therapy of bacillary dysentery, here reported, is based upon the experience of the present writer extending for a long time and consists of three principles, as the title indicates. As soon as a dysentery case is verified, solid food, which is selected from daily diet, is given, and then calomel in a large dose such as 1.0 to 3.0g. given, at the same time a hot compress is applied to the bowels, commonly on the left hypogastrium. The clinical symptoms soon apt to diminish; half a day to one day calomel stools passed, in which dysentery bacilli is found out. In subsequent one to two days all the symptoms disappear and no bacilli is detected, and stools have a normal appearance. The bacillary dysentery thus can be exterminated commonly within two to three days after the onset, provided the therapy be started as early as half a day to one day after onset. The earlier the better. And the trias of the therapy should be exactly kept. The recovery is so rapid, and no signs of intoxication, such as stomatitis, etc. No mortality in my recent experience extending for eight years at least. I am anxious to acknowledge exact data of recent outcome with sulfonamide and antibiotic drugs.View full abstractDownload PDF (808K) -
Itio Ono1953 Volume 57 Issue 2-3 Pages 273-281
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
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Koiti Motokawa, Mituru Ebe1953 Volume 57 Issue 2-3 Pages 283-292
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. It was shown with the “method of seeing-frequency” that the sensitivity of the human fovea to spectral light was enhanced during the passage of a subthreshold alternating current through the eye, if the combination of the wave-length of the test light and the frequency of the A. C. applied was adequate.
2. In a series of experiments performed with A. C. of varying frequencies and test light of a given wave-length, it was found that enhancement of sensitivity occurred only around certain definite frequencies. The optimal frequencies thus established were 77, 62.5, 52.5, 42.5, 35, 27.5, 20, and 7.5 c. p. s.
3. In another series of experiments in which wave-lengths were varied, sharp maxima of sensitivity appeared at 6 definite parts of the spectrum, namely at 650, 610, 575, 520, 465 and 415mμ. The frequencies of A. C. most adequate for revealing these maxima were higher for those at longer wave-lengths and lower for those at shorter wave-lengths.
4. The phenomenon under consideration was interpreted as due to summation of photochemically initiated and electrically evoked electrical changes at the level of intraretinal neurons.View full abstractDownload PDF (559K) -
Studies on the Antibiotic Substances from Aztinomyzes, 8th ReportMasami Kikuchi1953 Volume 57 Issue 2-3 Pages 293-297
Published: February 25, 1953
Released on J-STAGE: November 28, 2008
JOURNAL FREE ACCESS1. Several strains of antagonistic and non-antagonistic streptomyces were tested upon their abilities to grow on the streptomycin containing agar. Beside streptomycin producing ones, many strains were able to grow on the agar containing 10u/cc streptomycin, while only a limited number of streptomyces strains including streptomycin producing ones were capable to grow on the agar containing 100u/cc of streptomycin. Such a concentration of streptomycin, therefore, appeared to be specific and suitable for isolation and preservation of streptomycin producing
strains.
2. Even if the streptomyces strains producing other kind of antibiotics than strptomycin became to grow luxuriantly on streptomycin containing agar, there was seen no tendency to produce streptomycin.
3. It was able to select some, even if weakly, antibiotic colonies from the non-antagonistic strans of streptomyces by serial passages through streptomycin containing agars, although it was impossible to decide whether they were truely streptomycin producing ones, or not. The antibiotic strains thus obtained inhibited B. anthracis or Myco. phlei more strongly.
4. It was confirmed, that the streptomycin producing strains were reduced in colony numbers, became homogeneous in morphological properties and partially increased in inhibitory activities of culture filtrates, when they were cultivated on streptomycin containing agar through several generations.View full abstractDownload PDF (248K)
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