巻号一覧
94 巻 (1968)
- 4 号 p. 327-
- 3 号 p. 231-
- 2 号 p. 117-
- 1 号 p. 3-
94 巻, 1 号
選択された号の論文の10件中1～10を表示しています
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Tsuneo Arakawa, Tsunenobu Tamura, Ototaka Higashi, Kazuo Ohara, Kaneo ...1968 年 94 巻 1 号 p. 3-16
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーA third case of formiminotransferase deficiency syndrome was described, which was associated with megaloblastic-pyridoxine-folic acid-responsive anemia of probably congenital origin. The occurrence of megaloblastic pyridoxine-folic acid-responsive anemia was not observed in two cases of formiminotransferase deficiency syndrome previously reported by us.抄録全体を表示PDF形式でダウンロード (2134K) -
Hiroshi Kurihara, Jun Fujii, Hiroshi Yamaguchi, Masao Ikeda1968 年 94 巻 1 号 p. 17-21
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーA technique for measuring plasma angiotensinase of the rabbit is described. A mixture composed of 2.0ml of 1/15 AI phosphate buffer, 0.5ml of plasma, 0.5ml of saline and 1.0ml of saline containing 1μg of angiotensin is incubated at 37°C for 10 minutes and residual angiotensin is determined by the bracket technique on the rat blood pressure preparation. The plasma angiotensinase activity is indicated by percentage of inactivated angiotensin. Plasma angioten-sinase activity of 20 normal rabbits was 55.6±7%. It remained within normal limits in 5 renal hypertensive rabbits until the 40th week of operative renoarterial constriction.抄録全体を表示PDF形式でダウンロード (256K) -
Satoru Sakuma1968 年 94 巻 1 号 p. 23-35
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリー1) Electron-microscopic findings of the vascular system of the spleen and its relationship to the reticuloendothelial system are described.
2) In the white pulp, fine arterial blood vessels branch from the follicular artery and form a rich plexus of slender capillaries. The follicular arterioles are essentially similar in their fine structure to the arterioles of other organs.
3) The marginal zone of the white pulp is composed of phagocytic reticulum cells. Perifollicular sinusoids are poorly developed in the mouse spleen, but in the dog spleen wide perifollicular spaces form a boundary between the white and red pulp. Its basement membrane is broken in places and the wall is infiltrated by lymphoid cells, thrombocytes and erythrocytes.
4) Sheathed artery is found in the dog spleen. Sheath cells can be regarded as one of the phagocytic reticulum cells, which are differentiated from adventitial cells.
5) A large part of the terminal branches of the vascular system in the red pulp seem to end in a structure resembling a so-called finger-like extension. The basement membrane disappears abruptly and the edge of the vascular channel is structurally open. The open ending is protected by thrombocytes and reticulum cells.抄録全体を表示PDF形式でダウンロード (4144K) -
Takashi Kitabatake, Shinji Takahashi1968 年 94 巻 1 号 p. 37-43
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーA linear accelerator applied to conformation radiotherapy was described. The mechanism and dose distribution in the linear accelerator conformation radiotherapy were discussed, together with a comparison with those in telecobalt therapy. In this machine a collimator was divided into six leaves, which were driven independently by a servo system following signals given by the signal generator. The mechanical error in this system was within a range of +1.47 to-1.80%. The size and shape of radiation-dense area, ‘beam focus’, made by this unit sufficiently coincided geometrically with the region of planned treat-ments. The homogeneity of dose distribution was better than that by telecobalt gamma-rays.抄録全体を表示PDF形式でダウンロード (1259K) -
Chikako Sato, Masatoshi Sakka, Tadashi Hashizume1968 年 94 巻 1 号 p. 45-53
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーAnalysis of Sr and measurements of radioactivity of 90Sr were made on bones obtained from 43 leukemic patients at autopsy performed over a period from 1962 to 1965 at the Department of Pathology, Tohoku University School of Medicine. The quantity of 90Sr in the bones of leukemic patients averaged 3.17±2.69/μμCi Sr/ gCa in cases under 19 years of age and 0.47±0.31μμCi Sr/gCa over 20 years of age. These values are not significantly different from those of normal Japanese. Bone marrow dose from intraosseous 90Sr was estimated at 2. 22 and 0. 33 millirads per year for each age group, respectively. These levels are much lower than the estimated marrow dose of 52. 8 millirads per year at average medical exposure.抄録全体を表示PDF形式でダウンロード (448K) -
Tsuguo Shikata1968 年 94 巻 1 号 p. 55-61
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーMany reports have been made about prolonged survival of transplanted organs by intended decrease of lymphocytes, which are intimately related to homograft rejection.
The author injected 198Au colloid into recipients' lymphatics for selective blockade of lymphatic tissues and proved that this method was applicable to clinical renal transplantation.
After transitory clamping of the thoracic duct at the venous angle, 198Au colloid was injected into lymphatic vessels on the dorsal side of both feet.
By this method, the mesenterial lymphnodes were also blocked so that 198Au col-loid was hardly moved into blood stream. Clamping was released 24 hours after injection. Peripheral lymphocytes began to decrease on the 4th day of injection, and one week later attained a level of 0-2%. The author's clinical data showed that a lymphocyte level of 7-8% was maintained even after six months. It is interesting that only γ-globulin levels were decreased in parallel with the lymphocyte counts.
This safe and simple method can reduce the dosis of immunosuppressants to a minimum and prolong the survival of either experimentally or clinically trans-planted kidneys. Second set reaction is also strongly suppressed.抄録全体を表示PDF形式でダウンロード (383K) -
Tatsuo Koyanagi, Shoji Yamada1968 年 94 巻 1 号 p. 63-68
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーThe effects of supplementary feeding with niacin were investigated upon gastric acidity and vitamin B12 binding capacity of the gastric mucosa in rats which had been placed on two kinds of basal diets: low-protein diet composed of polished rice, fermented soy bean paste and cabbage, and a normal-protein diet sup-plemented with casein, gelatin and several amino acids.
Five and half months after the feeding, hyperfunction of acid secreting cells associated with increased gastric acidity was observed in rats fed on the low-protein-niacin-deficient diet rather than in rats on the normal niacin-protein diet.
Vitamin B12 binding capacity of the gastric mucosa of rats which has been said to be in parallel with the secretion of intrinsic factor was found to be higher in the low-protein-niacin-deficient group than in the normal-niacin-protein group.抄録全体を表示PDF形式でダウンロード (979K) -
Tsuneo Shiratori, Toshihiko Okabayashi, Kyoji Sugawara, Nobumasa Harat ...1968 年 94 巻 1 号 p. 69-80
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーTo elucidate motor function of the pylorus, manometric and electromyographic studies were carried out on the canine stomach following transection and end-to-end anastomosis at various levels such as proximal 1/3, 1/2, distal 1/3, distal 1/4. and at 4, 3, 2, and 1cm proximal to the pyloric ring.
Transections at the body of the stomach caused slight or no increase in contrac-tion pressure of the pylorus, a slight increase in the incidence of anti-peristalsis and slight or no prolongation of the discharge interval. On the other hand, transection at the borderline between the corpus and antrum of the stomach resulted in a marked increase in contraction pressure of the pylorus, a marked increase in the incidence of anti-peristalsis and a marked prolongation of the discharge interval. The results suggested excitation of the pylorus. As the level of transec-tion approached the pyloric ring, the electromyogram taken from the pylorus showed the evidence of excitation but the contraction pressure of the pylorus gradually lowered, probably because of a small amount of muscular remnant in the pyloric portion. The contraction pressure of the pylorus was approximately equal to the control value when a transection was made at 1.5 to 2.0cm proximal to the pyloric ring.抄録全体を表示PDF形式でダウンロード (654K) -
Shinichiro Endo, Takao Shinoki1968 年 94 巻 1 号 p. 81-101
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーExperimental studies were performed to clarify the non-specific defense mechanism of the host (Donryu rat) against tumor growth, chiefly from the view-point of the function of the reticuloendothelial system (RES). The functional activity of the RES, as determined by carbon clearance and the percentage of subcutaneous prehistiocytes, and the grade of the growth of rat ascites hepatoma cells (AH-130) were studied following the intraperitoneal administration of various agents such as polyvinyl pyrolidone (PVP), Evans blue and zymosan. In rats treated with PVP or Evans blue, the RES-function was inhibited and tumor growth was not influenced, whereas in rats administered with zymosan the RES-function was stimulated and tumor growth was inhibited. Thus, intraperitoneally admin-istered zymosan was proved to be effective in tumor inhibition; however, it was also ascertained that zymosan itself did not influence tumor growth in vitro. In addition, almost similar tumor inhibition to that in zymosan treated rats was observed with the recipient rats, which received peritoneal reactive cells obtained from the ascites of zymosan treated donor rats.
Such tumor inhibition, induced by transferred peritoneal reactive cells, was most pronounced in cases which had received these cells prior to tumor inocula-tion. In addition, this tumor inhibitory effect became more prominent from about the 7th day of tumor inoculation.
It seems adequate to assume from these results that the resistance of the host pretreated with zymosan against tumor growth can be sustained by ‘reactivity of the peritoneal cavity’ to zymosan or a ‘non-specific defense mechanism’ linked to the hyperactivity of the RES induced by zymosan.抄録全体を表示PDF形式でダウンロード (2697K) -
Tsutomu Watanuki, Katsuhiro Nakamura, Sadao Takase, Nobuhiko Takahashi1968 年 94 巻 1 号 p. 103-115
発行日: 1968年
公開日: 2008/11/28
ジャーナル フリーThe details of different manifestation patterns of experimental leprous lesions of mice were described from the viewpoint of host vs. parasite relationship and the reticuloendothelial origin of the lepra cell. Three kinds of pretreatment, i. e., typhoid vaccine as a stimulant, Evans blue as a disturbant and cardiolipin as a depressant of the reticuloendothelial function were given to mice of dd-strain before the inoculation of lepra bacilli of Hawaiian strain. The experiments were carried out up to 15 weeks of the infection. The results obtained by histological, hematocytological, electronmicroscopic and enzymohistochemical methods were as follows:
1) The manifestation types of leprous lesion were significantly influenced by functional activity of the reticuloendothelial system of the host.
2) Lepra cells developed from the histiocyte and its precursor, the prehistio-cyte, in the loose connective tissue proper.
3) The functional maturity of histiocytes as indicated by the digestion activity on the bacilli determined whether the involved cells were transformed into the lepra cell or not.抄録全体を表示PDF形式でダウンロード (3612K)
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