Viva Origino
Online ISSN : 1346-6933
Print ISSN : 0910-4003
29 巻, 1 号
  • Makoto Kodama, Masayo Ogiso, Yuko Momose, Noriko Fujii, Shinobu Ojima, ...
    2001 年 29 巻 1 号 p. 45-54
    発行日: 2001年
    公開日: 2022/02/23
    ジャーナル フリー

      It was found by light microscopic observation, using phosphomolibdenic acid hematoxylin and Alcian blue stains, that vitreous body has a three-dimensional meshwork structure and the beads are located at positions of joints in the fibrils. The HA coats the outer surface of the meshwork fibrils and the beads. The protein beads may reinforce the whole meshwork structure. One of non-collagenous protein beads is identified as αA-crystallin, which is a major component of the lens. It was suggested that vitreous liquefaction is induced by deformation of meshwork fibril structure and detachment of the non-collagenous protein beads, located at the joint of meshwork structure, resulting in the collapse of the structure to release watery liquid trapped within the meshwork.