The following 2-aminovinyl-benzothiazole ethiodide were prepared to use them as chemotherapeutic remedies. When condensed 2, 2′-dimethoxy-diphenyl-formamidine upon 2-methyl-benzothiazole ethiodide (I). 2-{ω-[
o-methoxy-anilido]-vinyl}-benzothiazole ethiodide of m.p. 232° (decomp.) is readily obtained The ethiodide (I) also combines with 4, 4′-diethoxy-diphenyl-formamidine at about 90° to form 2-{ω-[
p-diethoxy-anilido]-vinyl}-benzothiazole ethiodide of m.p. 194-196° (decomp.) and 3, 3′-diethyl-2, 2′-trimethine-benzothiazolocyanine (3) iodide (II) of m.p. 268° (decomp), while at about 110° chiefly the latter dyestuff (II). Again, on heating the ethiodide (I) respectively with 5, 5′-dichloro-2, 2′-dipyridylformamidine, 5, 5′-dibromo-2, 2′-dipyridyl-formamidine and 5, 5′-diiodo-2, 2′-dipyridyl-formamidine, 2-{ω-[5′-chloropyridyl-(2′)-amino]-vinyl}-benzothiazole ethiodide of m.p. 236° (decomp.), 2-{ω-[5′-bromopyridyl-(2′)-amino]-vinyl}-benzothiazole ethiodide of m.p. 239° and 2-{ω-[5′-iodopyridyl-(2′)-amino]-vinyl}-benzothiazole ethiodide of m.p. 236-9°, are produced.
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