Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
28 巻, 5-6 号
選択された号の論文の6件中1~6を表示しています
  • I. GEOGRAPHICAL AND SEASONAL FEATURES OF CASE OUTBREAKS
    TAKESHI OKUNO, PO-TSUNG TSENG, SHU-TAO HSU, CHIEN-TAO HUANG, CHAO-CHI ...
    1975 年 28 巻 5-6 号 p. 235-253
    発行日: 1975年
    公開日: 2010/03/19
    ジャーナル フリー
    During 1968-1971 Japanese encephalitis (JE) surveillance was conducted with WHO-assisted programs in Taiwan area. Emphasis was placed on: (1) active case-finding by hospital visits; (2) blood collection from every patient at the suitable time; and (3) the enforcement of standard diagnostic criteria on the results of hemagglutination-inhibition tests.
    Each year, approximately 90% of reported patients were etiologically examined. JE virus etiology was established in 277 (1968), 279 (1969), 269 (1970) and 158 (1971) cases. Despite the apparent concentration of cases in several cities, practically all the cultivated plains and basins were established as potentially endemic for JE.
    JE outbreak is found to have been clearly associated with season, not only in subtropical but also in tropical Taiwan. Each year it occurred consistently in mid July in the southernmost county, 2-3 weeks after the peak of rice transplantation and its duration was a few weeks. On the western side of the island, although less consistently, JE outbreak seems to occur one to three weeks later than in the south. Outbreak in eastern Taiwan was a mid-September phenomenon for 3 years. Observed seasonal lag, which was significant between two neighboring localities on same latitude, suggests that paddy water management is more directly related to date of outbreak than local climate. Seasonal characteristics further suggests that the area may be separated into eight ecologic subdivisions.
    JE-virus transmission to a man during April at temperatures below the average of 20 C was discussed.
  • II. AGE-SPECIFIC INCIDENCE IN CONNECTION WITH JAPANESE ENCEPHALITIS VACCINATION PROGRAM
    TAKESHI OKUNO, PO-TSUNG TSENG, SHU-TAO HSU, CHIEN-TAO HUANG, CHACO-CHI ...
    1975 年 28 巻 5-6 号 p. 255-267
    発行日: 1975年
    公開日: 2010/03/19
    ジャーナル フリー
    A baseline age/morbidity pattern for Japanese encephalitis (JE) epidemic in China (Province of Taiwan) in the 1960s was sought in JE surveillance. The pattern is characterized by: (1) high incidence in age groups 2-4 years, (2) moderately high incidence in age groups 5-7 years, (3) negligible incidence in children under 1 year of age as well as in adults, and (4) the variability of relative height of peak incidence co-incident with the JE-epidemic size in situ.
    Concurrently with surveillance, a JE-vaccination program was implemented by the Government. The children of target age groups received two doses of vaccine each year during April. Vigilant supervision was given to the campaign to achieve a high coverage rate with two-dose vaccination and meticulous record-keeping. During 1969-1972, 2-year olds were the exclusive target; 52.2% (1969), 71.5% (1970), 74.5% (1971) and 83.0% (1972) of the target age group were covered.
    A considerable change from the baseline age/morbidity pattern seen in 1968 occurred during the above period. The comparison of epidemicity-adjusted incidence by year indicates that incidence reduction in the 2- and 3-year-old children in 1971 were substantial and suggests the possible impact of vaccination. The total JE incidence for the period 1968-1971 appears to be much lower in vaccinated population (23 reported and 8 confirmed/0.9 million) than in unvaccinated population (1, 330 reported and 679 confirmed/2.2 million) .
  • 石山 紘, 安田 純一, 奥山 堅司, 増田 和茂, 伊藤 碩候
    1975 年 28 巻 5-6 号 p. 269-277
    発行日: 1975年
    公開日: 2010/03/19
    ジャーナル フリー
    Human HBs antibody was isolated by affinity chromatography on HBs antigen absorbed to concanavalin A linked to Sepharose 4B. When a human anti-HBs immunoglobulin preparation obtained by Cohn's cold ethanol fractionation method was used as a starting material, the antibody was concentrated about 10 times in terms of the passive hemagglutination titer with a recovery rate higher than 50%.
    Latex particles coated with human anti-HBs antibody thus prepared were proved to be useful in detecting HBs antigen in human blood samples. In its sensitivity and in rapidity of its performance, the antibody-coated latex agglutination test seems to be superior to conventional immunodiffusion techniques.
  • 田村 慎一, 江頭 靖之
    1975 年 28 巻 5-6 号 p. 279-283
    発行日: 1975年
    公開日: 2010/03/19
    ジャーナル フリー
  • 北岡 正見, 森 守, 有光 佳子
    1975 年 28 巻 5-6 号 p. 285-290
    発行日: 1975年
    公開日: 2010/03/19
    ジャーナル フリー
  • 1975 年 28 巻 5-6 号 p. 291-340
    発行日: 1975年
    公開日: 2010/03/19
    ジャーナル フリー
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