巻号一覧
30 巻, 6 号
選択された号の論文の5件中1～5を表示しています
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倉田 毅, 青山 友三, 北村 敬1977 年 30 巻 6 号 p. 283-296
発行日: 1977年
公開日: 2010/03/19
ジャーナル フリーThe pathogenicity of the Lister (Elstree) strain, a vaccinia virus, in rabbits after intravenous injection was studied by histopathological and immunofluorescent methods. Inoculation of 1×107PFU (pock-forming unit) virus into weanling and young adult rabbits caused severe emaciation and high mortality within 2 weeks. Pathological findings were characterized by vesicular lesions along muco-cutaneous junction areas of the eyes, nose and mouth and by inflammatory changes in the brain, mainly in the meninges and choroid plexus. Immunofluorescent staining of the tissues of animals sacrificed at intervals demonstrated the accumulation of vaccinia viral antigen (s) in the loci of pathological changes. The suitability of this model system for the study of pathogenesis of human postvaccinal meningoencephalitis is discussed.抄録全体を表示PDF形式でダウンロード (13876K) -
粕谷 志郎, 大友 弘士, 石崎 達1977 年 30 巻 6 号 p. 297-307
発行日: 1977年
公開日: 2010/03/19
ジャーナル フリーHighly purified eosinophil (Eos) fractions were obtained from peritoneal exudate cells of guinea pigs immunized withAscarislumbricoides swumantigen. (Asc) . These Eos suppressed the in vitro DNA synthesis of the lymph node cells (LNC) sensitized with Asc and then activated by this antigen or phytohemagglutinin (PHA) .
Although addition of Eos did not affect the viability of LNC in vitro, the blastformation of LNC was suppressed remarkably when 5-10×105purified Eos were added to 106LNC within 48 hr after the start of stimulation by Asc. The suppressive effects of Eos on the blastformation of LNC immunized with complete Freund's adjuvant with or without ovalbumin were observed when stimulated with purified protein derivatives or ovalbumin. Such suppression was observed beyond the barrier of animal strain specificity; Eos from Hartley guinea pigs suppressed proliferation of LNC from either strain 13 or strain 2, and Eos from strain 13 suppressed that from strain 2.
Such suppressing activity of Eos was reduced by heating them at 56 C for 1 hr or by sonication.抄録全体を表示PDF形式でダウンロード (969K) -
武本 寿行, 吉田 光昭1977 年 30 巻 6 号 p. 309-315
発行日: 1977年
公開日: 2010/03/19
ジャーナル フリーPDF形式でダウンロード (655K) -
近藤 瑩子, 金井 興美1977 年 30 巻 6 号 p. 317-320
発行日: 1977年
公開日: 2010/03/19
ジャーナル フリーPDF形式でダウンロード (344K) -
ROWLAND J. S. TAN, EK WANG LIM1977 年 30 巻 6 号 p. 321-323
発行日: 1977年
公開日: 2010/03/19
ジャーナル フリーPDF形式でダウンロード (280K)
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