Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
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Volume 42, Issue 3
Displaying 1-3 of 3 articles from this issue
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  • COMPARISON OF IMMUNE RESPONSES TO DIPHTHERIA AND TETANUS TOXOIDS OF VARIOUS MOUSE STRAINS
    Shoichi KAMEYAMA, Fumiko NAGAOKA, Tyoku MATUHASI
    1989 Volume 42 Issue 3 Pages 83-99
    Published: 1989
    Released on J-STAGE: March 19, 2010
    DOIhttps://doi.org/10.7883/yoken1952.42.83
    JOURNAL FREE ACCESS
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    Immune responses of 11 mouse strains with. known genetical characteristics and two outbred strains to diphtheria and to tetanus toxoids were compared. Both diphtheria and tetanus antitoxins were titrated by passive hemagglutination. From the pattern of the immune response, the mouse strains tested may be classified into four groups. [1] Strains ddY (SPF) and ddY (cony) and those with haplotype H-2b, such as C57BL/6 and C57BL/10, were high responders to both toxoids. [2] Strains with H-2d, such as BALB/c, B10.D2 and DBA/2Cr, were intermediate responders to both toxoids. [3] Strains with H-2k, H-2a or, H-2m, such as C3H/He, B10.BR, B10.BR/SgSn, B10.A/SgSnJ and B10.AKM/Ola, were high responders to diphtheria toxoid but low responders to tetanus toxoid. [4] The strain with H-2h4, B10.A (4R), was a poor responder to both toxoids.
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  • ANALYSIS OF LYMPHOCYTE RESPONSE TO CHIRONOMID MIDGE ANTIGENS IN ASTHMATIC AND NON-ASTHMATIC INDIVIDUALS
    Toru EDAHIRO, Nobuo OHTA, Hiroyuki MATSUOKA, Akira ISHII, Yoshiro TANI ...
    1989 Volume 42 Issue 3 Pages 101-110
    Published: 1989
    Released on J-STAGE: March 19, 2010
    DOIhttps://doi.org/10.7883/yoken1952.42.101
    JOURNAL FREE ACCESS
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    Chironomid antigens are currently one of the important allergens for bronchial asthma in Japan. We evaluated in vitro responses of peripheral blood lymphocytes (PBLs) to chironomid antigens and compared these responses with serum IgE levels. PBLs from adult asthmatic patients showed stronger proliferation in response to the extract of adult midges of Chironomus yoshimatsui compared with healthy adults. On the other hand, elevated PBL responses of child asthmatic patients to chironomid antigens were not observed. There was no significant correlation between PBL proliferation and the serum IgE level. Our results might suggest that elevated PBL proliferation in response to chiromid allergens has somehow important pathogenic roles in adult cases although this does not correlate directly with specific IgE production.
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  • THE PHYLOGENETIC SYSTEMATICS OF THE MILTOGRAMMATINE FLIES (DIPTERA, SARCOPHAGIDAE) OF THE WORLD
    Yu. G. VERVES
    1989 Volume 42 Issue 3 Pages 111-126
    Published: 1989
    Released on J-STAGE: March 19, 2010
    DOIhttps://doi.org/10.7883/yoken1952.42.111
    JOURNAL FREE ACCESS
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    A new system of Miltogrammatinae is proposed. Forty-six characters were coded in plesiomorphic and apomorphic states. The subfamily consists of six tribes, which are devided into two phylogenetic branches: Chorezmomyiini-Oebaliini-Metopiini and Miltogramrnatini-Phyllotelini-Amobiini. The phylogenetic relationships of subtribes and genera are also discussed. Five new subtribes are described: Mesomelaenina, Phrosinellina, Sphenometopiina (Metopiini) ; Lampometopiina (Phyllotelini) and Aenigmetopiina (Miltogrammatini) .
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