The Yamamoto Dokushoshitsu, a private school of natural history and Chinese classics in Kyoto, continued its activities over a 120-year period 1784 to 1903. Yamamoto Bōyō (1778– 1859), a disciple of the naturalist Ono Ranzan, inherited the school from his father Yamamoto Hōzan (1742–1813). The school reached its peak during the Ansei period (1854–1859).Yamamoto Ayao (1827–1903), the third son of Bōyō, reopened the school in 1875 as a means to maintain the Confucian and educational traditions of the Yamamoto family until his death in 1903. In 1893 he wrote the Senjin Genkōroku as a life of his late father following Confucian ideas of filial duty, but ten years later, in 1903, he rewrote it as a memoir containing, not only anecdotes about his grandfather Hōzan and his father Bōyō, but also histories of students, brothers and relatives and his own autobiography. Here we present for the first time the 1903 manuscript of Senjin Genkōroku with an introduction and notes. The introduction analyzes the process of its transformation using the family’s biographical documents.