Alternation in arterial blood and pulmonary function at various ventilatory situation were subjected to this experiment.
Rabits were used in this experiment, and placed on one of the following 3 maneuvers, i. e.:
1) Tracheal obstruction, 2) pleural thickening. 3) pneumoperitoneum.
The following instrumental setting were used after tracheostomy. These were;
1) Spirogram for gas exchange
2) Scholander for blood gas anlysis
3) Vanslyke microgas analyzer for same purpose.
In the group with obstructed air way, ventilation effect was maintained in relatively adequate level despite of hypoventilation, although Sao
2 showed decreased value.
In the group with pleural thickening, there was no noticeable change atrest, however, there was decline of ventilation effect and limitation of ability on exertion.
In the group with pneumoperitoneum, markedly disturbed ventilation effect and elevation of Paco
2 were recognized even at rest.
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