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全文: "AMEDEO"
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  • Olga Bortolini, Antonio De Nino, Marco Fogagnolo, Giancarlo Fantin, Loredana Mariuolo, Amedeo Tocci
    Chemistry Letters
    2007年 36 巻 3 号 472-473
    発行日: 2007/03/05
    公開日: 2007/02/24
    ジャーナル 認証あり
    電子付録
    Hydrogen peroxide serves as an efficient oxidant for the nitroalkene C=C bond cleavage to aldehydes in ionic liquids.
  • Tomonao Matsushita
    Plant Biotechnology
    2011年 28 巻 5 号 515-519
    発行日: 2011/12/25
    公開日: 2012/02/20
    [早期公開] 公開日: 2011/12/28
    ジャーナル フリー
    Transcriptional gene silencing (TGS) is a phenomenon by which transgenes that share homology in their promoter regions are inactivated. TGS is known to be reduced by using different promoters to drive the expression of each transgene. However, in order to perform a large-scale genetic screen in which overexpression lines are mutagenized by T-DNA tagging and therefore harbor two types of transgene, it is critical to develop a technique that consistently blocks TGS. Here, I report a versatile method that completely prevents TGS in transgenic Arabidopsis. A seedling morphology-based assay demonstrated that TGS could be significantly diminished by using different terminator sequences for each transgene. Furthermore, it was suggested that TGS might be reduced if the orientations of the two T-DNA sequences were reversed relative to each other. By combining these strategies, I showed that TGS was completely blocked in over 50,000 T1 plants. These findings present a thorough and versatile method to prevent TGS that is potentially applicable to various plant species and is expected to be used in diverse situations, from basic to applied research fields.
  • 鎔接協会誌
    1939年 9 巻 4 号 222
    発行日: 1939年
    公開日: 2011/08/05
    ジャーナル フリー
  • 木幡 桂, 藤原 亨, 山本 譲司, 山田 実名美, 石澤 賢一, 佐藤 和重, 関口 悟, 亀岡 淳一, 里見 進, 張替 秀郎
    日本臨床免疫学会会誌
    2010年 33 巻 1 号 20-23
    発行日: 2010年
    公開日: 2010/02/28
    ジャーナル フリー
      ABO一致生体肝移植後に発症した重症自己免疫性溶血性貧血(AIHA)を経験したので報告する.症例は56歳男性,2007年7月に,息子をドナーとして生体肝移植を受け,術後経過は良好であったが,移植後8週後よりビリルビンの上昇,貧血が進行.Direct Antiglobulin Test (DAT)陽性であり,自己免疫性溶血性貧血(AIHA)の診断にて,プレドニゾロン,アザチオプリン,リツキシマブの投与に加え,血漿交換を実施したが,治療抵抗性であった.サイクロフォスファミドパルス療法とリツキシマブの併用にて,最終的に寛解が得られた.現在,DATも陰性化し無治療にて経過観察中である.本症例のAIHAの発症機序は明らかではないが,肝移植を契機に発症しており,極期の重症度に比較してその後の経過が良好であることから,その発症にドナー由来リンパ球が関与している可能性が否定できないと考えられた.
  • 松原
    東京化學會誌
    1909年 30 巻 12 号 1368-1370
    発行日: 1909年
    公開日: 2009/02/05
    ジャーナル フリー
  • 石原 潤
    人文地理
    1974年 26 巻 6 号 686-688
    発行日: 1974/12/28
    公開日: 2009/04/28
    ジャーナル フリー
  • Shu IMAIZUMI, Akira IWAYA, Haruo HIBINO, Shinichi KOYAMA
    デザイン学研究
    2015年 62 巻 3 号 3_35-3_38
    発行日: 2015/09/30
    公開日: 2016/04/12
    ジャーナル フリー
    Patients with migraine are susceptible to visual discomfort. Some painters who suffer from migraine express their migraine experience and visual discomfort through their paintings, which we refer to as migraine art. Several famous painters (e.g., Picasso) also have been reported to suffer from migraine; therefore, we refer to their paintings as "possible-migraine art." Although paintings with excessive energy at mid-spatial frequencies are uncomfortable to view, it remains unknown whether migraine art and possible-migraine art contain spatial characteristics that contribute to visual discomfort. We performed a spatial-frequency analysis on migraine art, possible-migraine art, and non-migraine art images. The results revealed that migraine art contains more energy at mid-spatial frequencies than non-migraine art. Possible-migraine art also contains this spectral characteristic. We propose that painters who suffer from migraine may utilize rather than avoid spatial characteristics that contribute to visual discomfort.
  • Miku YOSHIDA
    日本科学教育学会研究会研究報告
    2016年 31 巻 4 号 1-4
    発行日: 2016年
    公開日: 2018/04/07
    研究報告書・技術報告書 フリー
    This research aimed at exploring science teachers’ subject specific beliefs in Denmark and Japan. Phenomenological approach has been taken in order to analyse semi-structured interview data from 6 in-service science teachers at lower middle school from each Denmark and Japan. As a result, Danish teachers showed the importance of interest and curiosity as a commonality while Japanese teachers showed more focus on helping students’ understandings. It showed different subject specific beliefs reflected in their practices.
  • 武藤 伸
    化学と教育
    1988年 36 巻 1 号 96-97
    発行日: 1988/02/20
    公開日: 2017/07/13
    解説誌・一般情報誌 フリー
  • Pietro Amedeo Modesti, Eleonora Perruolo, Gianfranco Parati
    Journal of Epidemiology
    2015年 25 巻 2 号 91-98
    発行日: 2015/02/05
    公開日: 2015/02/05
    [早期公開] 公開日: 2014/11/22
    ジャーナル フリー
    Hypertension is now the foremost cause of disability and is responsible for the highest percentage of attributable death among risk factors. These global changes are mainly due to the increase in the prevalence of hypertension in most low- and middle-income countries (LMICs) as a consequence of relevant socioeconomic changes occurring during the last decades. Implementation of global prevention efforts urgently needs to be accelerated because of the increasing incidence of haemorrhagic stroke, renal failure, and hypertensive heart disease in developing countries. Blood pressure (BP) measurement has different implications in epidemiological studies performed in low-resource settings. First, the frequency of blood pressure measurement is a simple but reliable indicator of access to healthcare in epidemiological studies, which may disclose the favourable effects of urbanization; the opportunity to have BP measured increases hypertension awareness, facilitates drug treatment, and leads to better achievement of BP control. Second, BP measurement is a key element in cardiovascular risk stratification, focusing solely on the preferred strategy in low-resource settings where costs of biochemical tests might be less sustainable. Third, the issue of obtaining reliable estimation of BP values is crucial to achieve sound data on the burden of hypertension in LMICs, and some aspects of BP measurement, such as the use of reliable automated devices, the number of measurements/visits to achieve a consistent diagnosis of hypertension, and the possible confounding effect of environmental factors, must be closely considered.
  • Mamoru UMEDA, Tsugiyasu KANDA, Masami MURAKAMI
    Hypertension Research
    2003年 26 巻 6 号 485-492
    発行日: 2003年
    公開日: 2003/12/31
    ジャーナル フリー
    In order to investigate the usefulness of angiotensin II type 1 receptor (AT1) antagonists (ARA) in the treatment of hypertension with insulin resistance syndrome, we studied the effects of a high dose sucrose diet and ARA on insulin sensitivity, plasma lipids, and leptin in spontaneous hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). SHR and WKY were divided into three groups and treated for 12 weeks: those fed a standard chow, those given a sucrose-rich chow or those given a sucrose-rich chow and ARA. While in SHR the weight of both subcutaneous and mesenteric adipose tissue was greater in the sucrose-rich chow fed animals than in the standard chow fed animals, ARA treatment significantly decreased the weights of both subcutaneous and mesenteric adipose tissue. ARA treatment decreased free fatty acid and triglyceride in SHR, and increased high density lipoprotein cholesterol in SHR and WKY. Homeostasis model assessment-insulin resistance (HOMA-IR) index, plasma levels of leptin, and leptin mRNA in mesenteric adipose tissue were significantly greater in the sucrose-rich chow fed animals than in the standard chow fed animals, and significantly lower in the ARA-treated sucrose-rich chow fed animals than in the sucrose-rich chow fed animals in both SHR and WKY. ARA improved insulin resistance, and reduced plasma leptin and leptin mRNA in adipose tissue. These results suggest that the improvement of insulin resistance by ARA may be attributed, at least in part, to the reduction of adipose tissue weight. It is concluded that ARA is useful in the treatment of patients with hypertension and concomitant insulin resistance syndrome. (Hypertens Res 2003; 26: 485-492)
  • Pierluigi IMBIMBO, Lorenzo CASTIGLIEGO, Andrea ARMANI, Bartolomeo BIOLATTI, Francesca Tiziana CANNIZZO, Daniela GIANFALDONI, Alessandra GUIDI
    Journal of Veterinary Medical Science
    2012年 74 巻 10 号 1253-1259
    発行日: 2012年
    公開日: 2012/11/02
    [早期公開] 公開日: 2012/05/22
    ジャーナル フリー
    A gross pathology and histological investigation was carried out on bovine target organs of anabolic substances in the Molise Region (Italy). One hundred forty-four bovines (12–24 months old, 123 males and 21 females) were included in the survey. An antemortem assessment of their behavior and clinical examination were performed. After slaughter, samples of prostate, Cowper’s glands, Bartholin’s glands, mammary gland, ovaries, thymus and thyroid were collected, inspected and processed for histopathology, as suggested in the guidelines of the Italian national program for residue surveillance (PNR). Overall, 15.3% of the examined animals were classified as “suspect,” 44.4% were classified as “uncertain,” and the remaining 40.3% were classified as “negative.” The most frequent lesion was a severe thymus atrophy with fat infiltration (15.4% of males and 14.3% of females), strongly suggesting the illegal use of corticosteroids.
  • Marco MORABITO, Lorenzo CECCHI, Alfonso CRISCI, Pietro Amedeo MODESTI, Simone ORLANDINI
    Industrial Health
    2006年 44 巻 3 号 458-464
    発行日: 2006年
    公開日: 2006/08/28
    ジャーナル フリー
    Nowadays, no studies have been published on the relationship between meteorological conditions and work-related mortality and morbidity in Italy. The aim of this study was to evaluate the relationship between hot weather conditions and hospital admissions due to work-related accidents in Tuscany (central Italy) over the period 1998-2003. Apparent temperature (AT) values were calculated to evaluate human weather discomfort due to hot conditions and then tested for work accident differences using non-parametric procedures. Present findings showed that hot weather conditions might represent a risk factor for work-related accidents in Italy during summer. In particular early warming days during June, characterized by heat discomfort, are less tolerated by workers than warming days of the following summer months. The peak of work-related accidents occurred on days characterized by high, but not extreme, thermal conditions. Workers maybe change their behaviour when heat stress increases, reducing risks by adopting preventive measures. Results suggested that days with an average daytime AT value ranged between 24.8°C and 27.5°C were at the highest risk of work-related accidents. In conclusion, present findings might represent the first step for the development of a watch/warning system for workers that might be used by employers for planning work activities.
  • MAY D. LEE, AMEDEO A. FANTINI, NYDIA A. KUCK, MICHAEL GREENSTEIN, RAYMOND T. TESTA, DONALD B. BORDERS
    The Journal of Antibiotics
    1987年 40 巻 12 号 1657-1663
    発行日: 1987/12/25
    公開日: 2006/04/19
    ジャーナル フリー
    The LL-D05139 complex, containing LL-D05139β and azaserine, was recovered from the fermentation filtrate of Glycomyces harbinensis (NRRL 15337). A chemically defined medium was developed which favored the production of LL-D05139β. Antibiotic LL-D05139β was isolated from the fermentation filtrate by adsorption on granular carbon and further purified by chromatography on microcrystalline cellulose. Acid hydrolysis of LL-D05139β gave one molar equivalent each of alanine and serine. Both amino acids were found to have the L-configuration by GC analysis on a chiral column and alanine was assigned to be the N-terminal amino acid by Edman degradation. This information coupled with IR, UV, 1H NMR, 13C NMR and MS spectral data allowed us to assign the structure of LL-D05139β as alanylazaserine. LL-D05139β demonstrated greater antibacterial and biochemical induction assay activities than azaserine. The two drugs showed similar antitumor activities.
  • 第2部 酸素切断作業(3)
    中川 清
    鎔接協会誌
    1941年 11 巻 7 号 239-249
    発行日: 1941年
    公開日: 2011/08/05
    ジャーナル フリー
  • 第2部 酸素切断作業(1)
    W. Spraragen, G. E. Claussen
    鎔接協会誌
    1941年 11 巻 5 号 154-167
    発行日: 1941年
    公開日: 2011/08/05
    ジャーナル フリー
  • 現象学的アプローチへの一考察
    吉田 実久
    日本科学教育学会年会論文集
    2017年 41 巻 2G1-C1
    発行日: 2017年
    公開日: 2018/08/16
    会議録・要旨集 フリー

    本研究は,科学教育の教育者の信念(belief)研究における質的分析方法としての現象学的アプローチの意義について検討を行った。信念研究に関する文献を整理し,日本の学校教員へのインタビューデータを現象学的アプローチに分析した結果,現象学的アプローチが教員の信念の振り返りとともに,教育の動機付けにつながる科学教育の意義を検討する上で有用である可能性が示唆された。

  • Amedeo CAPOZZOLI, Claudio CURCIO, Antonio DI VICO, Angelo LISENO
    IEICE Transactions on Communications
    2011年 E94.B 巻 7 号 2092-2103
    発行日: 2011/07/01
    公開日: 2011/07/01
    ジャーナル 認証あり
    We develop an effective algorithm, based on the filtered backprojection (FBP) approach, for the imaging of vegetation. Under the FBP scheme, the reconstruction amounts at a non-trivial Fourier inversion, since the data are Fourier samples arranged on a non-Cartesian grid. The computational issue is efficiently tackled by Non-Uniform Fast Fourier Transforms (NUFFTs), whose complexity grows asymptotically as that of a standard FFT. Furthermore, significant speed-ups, as compared to fast CPU implementations, are obtained by a parallel versions of the NUFFT algorithm, purposely designed to be run on Graphic Processing Units (GPUs) by using the CUDA language. The performance of the parallel algorithm has been assessed in comparison to a CPU-multicore accelerated, Matlab implementation of the same routine, to other CPU-multicore accelerated implementations based on standard FFT and employing linear, cubic, spline and sinc interpolations and to a different, parallel algorithm exploiting a parallel linear interpolation stage. The proposed approach has resulted the most computationally convenient. Furthermore, an indoor, polarimetric experimental setup is developed, capable to isolate and introduce, one at a time, different non-idealities of a real acquisition, as the sources (wind, rain) of temporal decorrelation. Experimental far-field polarimetric measurements on a thuja plicata (western redcedar) tree point out the performance of the set up algorithm, its robustness against data truncation and temporal decorrelation as well as the possibility of discriminating scatterers with different features within the investigated scene.
  • Stefano FRANGINI, Angelo Di BARTOLOMEO, Leonardo GIORGI, Amedeo MASCI
    電気化学および工業物理化学
    1996年 64 巻 6 号 508-512
    発行日: 1996/06/05
    公開日: 2019/09/15
    ジャーナル オープンアクセス
  • 中川 清
    鎔接協会誌
    1940年 10 巻 4 号 157-164
    発行日: 1940/04/25
    公開日: 2011/08/05
    ジャーナル フリー
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