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全文: "Angular gyrus"
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  • Masanori KURIMOTO, Takashi ASAHI, Takashi SHIBATA, Chiaki TAKAHASHI, Shoichi NAGAI, Nakamasa HAYASHI, Mie MATSUI, Shunro ENDO
    Neurologia medico-chirurgica
    2006年 46 巻 1 号 46-50
    発行日: 2006年
    公開日: 2006/01/25
    ジャーナル オープンアクセス
    A 67-year-old patient presented with progressive agraphia, alexia, and impaired ability to calculate persisting for 4 weeks. He showed preserved ability to do single-digit addition and subtraction. Magnetic resonance imaging demonstrated a tumor in the left parietal lobe. A malignant glioma was suspected, and awake craniotomy was performed to remove the tumor with functional cortical mapping to determine the cortices involved in calculation and language. His calculation ability was mapped on the angular gyrus, and partial resection of the tumor was achieved without deterioration of that ability. The histological diagnosis was glioblastoma multiforme. The patient’s calculation ability improved dramatically after the operation.
  • MAKOTO IWATA
    The Tohoku Journal of Experimental Medicine
    1990年 161 巻 Supplement 号 61-78
    発行日: 1990年
    公開日: 2011/03/14
    ジャーナル フリー
    Visual information processings are realized by the posterior association cortex spreading in front of the striate and parastriate areas from which two major visual association pathways arise. The dorsal or the occipito-parietal pathway which transmits the inputs from the peripheral as well as the central visual field to the parietal association cortex is responsible for the visuospatial analysis of the visual informations. The occipito-temporal or the ventral pathway originates only from the foveal vision area, and sends the visual inputs to the inferior temporal lobe which engages in visual pattern or whole gestalt recognition of the visual informations. In addition to this dichotomous disposition of the dorsal and the ventral visual association pathways in each cerebral hemisphere, there is another type of functional specialization which is hierarchical rather than dichotomous. In the left cerebral hemisphere, the collateral pathways arise from both dorsal and ventral main streams and engage in the process of reading, or the verbal mode of visual information processing.
  • Yasuhiro Funakoshi, Masafumi Harada, Hideki Otsuka, Kenji Mori, Hiromichi Ito, Takashi Iwanaga
    The Journal of Medical Investigation
    2016年 63 巻 3.4 号 204-208
    発行日: 2016年
    公開日: 2016/09/17
    ジャーナル フリー

    Purpose: The purpose of this study was to investigate changes in the functional connectivity of the default mode network (DMN) in normal aging and in children with autistic spectrum disorder (ASD) by using resting-state functional magnetic resonance imaging (rsfMRI) and independent component analysis. Methods: Thirty-one healthy controls (HC) in four age groups (1-3, 4-8, 20-29, and 50-59 years) and 14 childhood ASD cases (1-8 years of age) were examined by rsfMRI echo-planar imaging on a clinical 3-T MRI scanner. Imaging of all children (1-8 years) was conducted under sedation, while adults were scanned in the awake state with eyes closed. Results: The regions of DMN functional connectivity in the bilateral inferior parietal lobule and posterior cingulate cortex were smaller in HC children than in HC adults, and smaller in the ASD group than in the HC children. Conclusion: It is possible to observe developmental and pathological changes in the DMN by rsfMRI. Reduced DMN functional connectivity in children may be a useful biomarker for ASD diagnosis. J. Med. Invest. 63: 204-208, August, 2016

  • Ji Heon Hong, Sung Ho Jang
    Journal of Physical Therapy Science
    2011年 23 巻 1 号 97-101
    発行日: 2011年
    公開日: 2011/04/28
    ジャーナル フリー
    [Purpose] Little is known about the detailed anatomical connections of the neural network related to hand movement in the human brain. We investigated the neural network using diffusion tensor tractography (DTT) data analyzed in conjunction with functional MRI (fMRI) activation results. [Subjects and Method] We recruited 19 healthy volunteers for this study. Probabilistic tractography was used to analyze diffusion tensor imaging (DTI) data that were collected using fMRI activation induced by grasp-release movements of the hand at a rate of 1 Hz. [Results] The brain areas connected to the primary sensorimotor cortex (SM1), which is activated by hand movements, were the premotor cortex (100%), superior parietal lobule (100%), intraparietal sulcus (100%), supramarginal gyrus (97.37%), supplementary motor area (89.47%), thalamus (86.84%), putamen (81.58%), pars opercularis (81.58%), pars triangularis (68.42%), angular gyrus (65.79%), and cerebellum (60.53%) in the same hemisphere and the contralateral primary motor cortex (60.53%) in the opposite hemisphere. No significant difference was observed in the total incidence of connected tracts between hemispheres. [Conclusion] These results reveal that more brain areas are involved in hand movements than were previously thought necessary for motor planning and execution in the human brain.
  • Yukihisa Suzuki, Motohiro Kiyosawa, Kiichi Ishiwata, Keiichi Oda, Kenji Ishii
    The Tohoku Journal of Experimental Medicine
    2016年 240 巻 2 号 141-146
    発行日: 2016年
    公開日: 2016/10/08
    ジャーナル フリー HTML

    Bell’s phenomenon is a physiological phenomenon wherein the eye ball involuntarily rolls upward during eyelid closing. Although this phenomenon occurs in healthy individuals, the neural mechanism related to Bell’s phenomenon has not yet been identified. We aimed to investigate the brain regions relevant to Bell’s phenomenon and volitional eye movement using [15O] H2O and positron emission tomography (PET). We measured regional cerebral blood flow (rCBF) in 8 normal subjects under 3 conditions: at rest with eyes closed, during opening and closing of the eyelids in response to sound stimuli (lid opening/closing), and during vertical movement of the eyes with lids closed in response to sound stimuli (volitional eye movement). The supplementary motor area (SMA) proper, right superior temporal gyrus, right insular cortex and left angular gyrus were activated during lid opening/closing. The right frontal eye field (FEF), pre-SMA, left primary motor area, right angular gyrus, and SMA proper were activated during volitional eye movement. The SMA proper was active during both tasks, while the FEF and pre-SMA were active during volitional eye movement, but not during eyelid opening/closing. A comparison of activation during volitional eye movements and lid opening/closing tasks revealed a relative increase in rCBF in the FEF. There were no areas that are activated in relation to Bell’s phenomenon. In conclusion, activation in the FEF mainly occurs during volitional eye movement. Since Bell’s phenomenon is a reflexive eye movement, the FEF is scarcely concerned in Bell’s phenomenon.

  • Keiji TAKAMI, Akira SAKURAI, Fumio MUKAI, Takashi YAMADORI
    Okajimas Folia Anatomica Japonica
    1993年 70 巻 2-3 号 59-61
    発行日: 1993/08/20
    公開日: 2012/09/24
    ジャーナル フリー
    By means of a rubbed copy method using India ink and an image-analysis system (IBAS 2000), the areas of 106left-right plana temporalia were compared using fixed brains of both sexes. The left planum was of a larger size than the right planum in two-thirds of the cases. This result was confirmed statistically by the least-squares analysis of variance method (p<0.01).
  • Masanaka TAKEDA, Hisao TACHIBANA, Naomi SHIBUYA, Yatuka NAKAJIMA, Bungo OKUDA, Minoru SUGITA, Harumi TANAKA
    Internal Medicine
    1999年 38 巻 3 号 293-295
    発行日: 1999年
    公開日: 2006/03/27
    ジャーナル フリー
    There have been few case reports of pure anomic aphasia and the underlying mechanism remains to be clarified. We report a patient in whom pure anomic aphasia was caused by subcortical hemorrhage in the left temporo-parieto-occipital lobe. Based on magnetic resonance images and cerebral blood flow imaging, the structural lesion underlying the pure anomic aphasia was thought to be located at the left temporo-occipital junction.
    (Internal Medicine 38: 293-295, 1999)
  • 川村 光毅
    失語症研究
    1982年 2 巻 1 号 208-214
    発行日: 1982年
    公開日: 2006/11/22
    ジャーナル フリー
         The present paper deals with crticocortical connections of the posterior association cortex in cats, monkeys and man with particular empha sis on the most “developed” cortical region ; particularly the angular gyrus in man.
        Organization patterns of association fibers to the posterior association area are basically identical on several points in cats and monkeys. Thus, for example, convergence of association fibers from the somatosensory, auditory and visual cortical areas to a certain region in the posterior association area ( MSs, middle suprasylvian sulcus area in cat; STs, superior temporal sulcus area in monkey) is evident in both animal species. However, several dissimilarities, reflecting evolutionary development from carnivores to primates, do exist within the formation of some long association bundles, which have been revealed from a comparison of the findings obtained from the two kinds of animals.
        The angular gyrus (area 39) together with its adjacent areas can be considered from the evolutionary point of view as being homologue of part of the MSs and STs in the cat and monkey, respectively.
        Some aspects of the angular gyrus are discussed with relation to the monkey and crossmodal association (Geschwind, 1965), and the possibility of cortical connections between the angular gyrus and Broca's area is also commented with reference to our new findings obtained with the HRP method in monkeys.
  • Hong-Seng Gan, Tatsuya Suzuki, Koichi Yokosawa, Yumie Ono
    Advanced Biomedical Engineering
    2019年 8 巻 23-29
    発行日: 2019年
    公開日: 2019/01/09
    ジャーナル フリー

    Individual capacity of recall memory varies greatly even among healthy young adults. Nevertheless, the difference in brain circuitry underlying varied memory capacity has yet to be fully investigated. We acquired electroencephalographic measurements from 43 healthy young adults while performing a demanding working memory task and studied the changes in regional cortical activity in relation to different levels of memory performance. The memory task involved sequentially presenting seven arrow pictures to a participant during the encoding period, who was then asked to recall the direction of one of the arrows in the sequence within the retrieval period. We divided the participants into three groups of high, intermediate, and low performance based on the weighted hierarchical grouping method. Regional brain activities were source-localized using multiple sparse priors method in the high- and low-performance groups, and group differences were determined by non-parametric permutation tests. Our findings showed that participants with higher memory performance exhibited wider distribution of cortical activity including the prefrontal and parieto-posterior cortices, whereas lower performance participants only exhibited stable activations across occipital regions. The results implied the importance of selective attention in order to attain optimal individual working memory performance. Furthermore, we suggest the potential role of the angular gyrus as an interplay between the prefrontal and posterior regions for the management of stimulus flow and signal control. Future works should focus on conducting more thorough connectivity analysis to investigate the relationship of cortical activations with individual working memory performance.

  • 兒玉 裕司, 大西 英之, 垰本 勝司, 久我 純弘, 富永 貴志, 林 真人, 山下 太郎, 福留 賢二
    脳神経外科ジャーナル
    2012年 21 巻 6 号 495-500
    発行日: 2012/06/20
    公開日: 2017/06/02
    ジャーナル フリー
    Hemangiopericytomaの脳室内発生はまれである.われわれは,非優位半球側脳室三角部に発生した79歳女性の症例を経験したため報告する.腫瘍は最大径60mmで脳室内出血をきたし強い周辺浮腫を伴っていた.術前血管撮影所見にて腫瘍は豊富な血行を有し,術中出血量増多が予想された.神経学的異常のうち左半側空間無視,左同名半盲は回復不能と考えられた.この2点を考慮し,出血量を抑えるため広い術野を得るべく,腫瘍に近いangular gyrusを経由し摘出を行った.腫瘍は全摘出し出血量は420mlのみであった.
  • 福永 典子, 徳田 佳生
    The Japanese Journal of Rehabilitation Medicine
    2011年 48 巻 9 号 628-634
    発行日: 2011/09/18
    公開日: 2011/09/30
    ジャーナル フリー
    Paragraphia due to cerebellar cognitive affective syndrome (CCAS) has not been reported previously. This report presents a patient with cerebellar hemorrhage, showing cognitive dysfunctions including paragraphia. A 74-year-old right-handed man was hospitalized with sudden dizziness. CT demonstrated a small hemorrhage in the right cerebellar dentate nucleus. He also exhibited gait disturbance due to mild truncal ataxia and became aware of errors while writing his dairy. Neuropsychological assessments showed phonological paragraphia with Kana characters and semantic paragraphia with Kanji characters, as well as mild auditory comprehension and verbal memory disorders. Although MRI did not detect any abnormality in the cerebral hemispheres, SPECT demonstrated decreased cerebral blood flow in the left angular gyrus, frontal lobe and parieto-occipital lobe, predominantly on the left side. On neuropsychological assessment 3 months after stroke, the patient's paragraphia and auditory comprehension disorder had subsided, but his verbal memory disturbance remained. The clinical features in this case differed from those of CCAS cases previously reported. In particular, the lesion considered responsible for the cognitive dysfunctions in this case involved the right dentate nucleus, which is supplied by the superior cerebellar artery, but not the posterior inferior cerebellar artery, and especially the presence of dis-orders in writing ability, such as paragraphia. The possible mechanism of paragraphia in this case might be a reduction of cerebral blood flow in the angular gyrus due to a crossed cerebello-cerebral diaschisis. However, this case suggests that the right dentate nucleus contributes to the neuropsychological mechanism of writing.
  • Tetsuo Hamamatsu, Yoichi Nakagawa, Makoto Tamai, Masatoshi Ito
    The Tohoku Journal of Experimental Medicine
    2000年 190 巻 4 号 249-260
    発行日: 2000年
    公開日: 2005/05/25
    ジャーナル フリー
    Macular hole is a specific disease of the central retina that affects central visual acuity and central visual field. The purpose of this study is to investigate the alteration of visual processing in patients with macular hole who had small central scotoma. Six patients with macular hole participated in this study. We used positron emission tomography (PET) to measure task-related changes in regional cerebral blood flow to identify regions of the brain activated during visual stimulation. Three tasks were performed in each eye: control task, checkerboard task, shape-discrimination task. Checkerboard stimuli caused a greater blood flow activation response in normal eyes than in affected eyes at the occipital cortex. The area involved in the macular hole appeared to be 20 mm or more anteriorly from the occipital pole. The Shape-discrimination task in affected eyes activated angular gyrus, inferoparietal lobule, and middle frontal gyrus. Our findings demonstrated greater confidence in Horton's new retinotopic map than in Holmes' retinotopic map in cortical areas involved in macular function. The dorsal pathway of the visual system was activated more than the ventral pathway in patients with macular hole.
  • Takahiro YAMANOI, Toshimasa YAMAZAKI, Elie Sanchez, Michio SUGENO
    バイオメディカル・ファジィ・システム学会大会講演論文集
    2005年 18 巻
    発行日: 2005/10/29
    公開日: 2017/10/25
    会議録・要旨集 フリー
    The authors recorded nineteen-channel event-related potentials (ERPs) during recognition of two types of Japanese character ; Kanji (Chinese characters) and Hiragana (one type of phonetic characters). By field-sequential stereoscopic 3D display with liquid crystal shutter, a word and a non-word were simultaneously and independently presented to the left (right) eye and right (left) one, respectively. Each word consists of two Kanji or three Hiragana characters. Three subjects were instructed to press a button when understanding the meaning of the visual stimuli after 3000 ms poststimulus. Equivalent current dipole source localization (ECDL) with three unconstrained ECD was applied to the ERPs. For both Kanji and Hiragana, the ECDs were localized at the occipital and inferior temporal gyrus at 200 400ms, and those at the Wernicke area at 300 600ms. The latter ECD for one left-handed subject was localized at the homologue of Wernicke area.
  • 大東 祥孝, 浜中 淑彦
    失語症研究
    1982年 2 巻 1 号 225-235
    発行日: 1982年
    公開日: 2006/11/22
    ジャーナル フリー
         The author investigated first the clinical significance of so-called “Gerstmann syndrome” and secondly the anatomoclinical correlation between Gerstmann syndrome and left angular gyrus lesion. Conclusions obtained are as follows :
        1) Gerstman syndrome may not necessarily homogeneous. This point has already been indicated by many authors.
        2) Left angular gyrus lesionmight not be necessary and sufficient condition of manifestation of the Gerstmann syndrome, because of existence of cases with angular lesion without Gerstmann syndrome and of cases without angulra lesion with Gerstmann syndrome. However, it is not doubtful that almost all cases of Gerstmann syndrome have left parietooccipital lesions including angular gyrus.
        3) Why bilateral asomatognosia (Gerstmann syndrome and autotopagnosia) do appear with dominant parieto-occipital lesions is the problem which may be worth while to reexamine from neuropsychological point of view.
        4) A few cases reported of Gerstmann syndrome with frontal lobe lesions may suggest the presence of certain roles played by frontal lobe in somatognosic and spatial-gnostic processes, in contrast to that played by parietal lobe. We must investigate in the future this difficult problem which remains unsolved.
  • 名取 良弘
    脳神経外科ジャーナル
    2012年 21 巻 6 号 500-
    発行日: 2012/06/20
    公開日: 2017/06/02
    ジャーナル フリー
  • Yukihisa Suzuki, Motohiro Kiyosawa, Manabu Mochizuki, Kiichi Ishiwata, Kenji Ishii
    The Tohoku Journal of Experimental Medicine
    2010年 222 巻 2 号 97-104
    発行日: 2010年
    公開日: 2010/09/18
    ジャーナル フリー
    Blinking and opening/closing of the eyelid are considered to be different movements with independent control mechanisms. Apraxia of lid opening (ALO) is a clinical syndrome in which patients experience difficulty in opening their eyes voluntarily. Our previous study with fluorodeoxyglucose and positron emission tomography (PET) has suggested that functional impairments in the supplementary motor area (SMA) and the anterior cingulate gyrus may be involved in the pathophysiology of ALO. The aim of this study was to explore the physiological mechanisms for voluntary eyelid opening/closing and the difference between self-initiated and triggered movements, using [15O]H2O and PET. We measured the regional cerebral blood flow in 8 healthy subjects under 3 conditions: [A] at rest with eyes closed, [B] with self-paced lid opening/closing, and [C] with triggered lid opening/closing. All tasks were done with a blindfold to exclude the influence of visual input. The SMA proper and the angular gyrus were activated during self-paced and triggered lid opening/closing movements; however, the pre-SMA and the primary motor area (M1) were activated only during self-paced movements. The anterior cingulate gyrus and the cerebellum were activated during self-paced condition over triggered condition. The roles of SMA, M1 and cerebellum were assumed in eyelid opening/closing movements: the preparation and processing of movements in SMA, execution of movements in M1, and rhythmic generation in pre-SMA, M1 and cerebellum. We suggest that the activation in pre-SMA, anterior cingulate gyrus, and cerebellum may be responsible for the self-initiated eyelid opening/closing movements.
  • Hiroki Masuda, Shoichi Ito, Shigeyuki Kojima, Satoshi Kuwabara
    Internal Medicine
    2013年 52 巻 20 号 2347-2349
    発行日: 2013年
    公開日: 2013/10/15
    ジャーナル オープンアクセス
    Pseudoperipheral palsy can be caused by cerebral cortical infarctions; however, it is rarely caused by lacunar infarctions, including those in the posterior limb of the internal capsule. Meanwhile, the somatotopic localization of the corticospinal tract in the posterior limb of the internal capsule remains unknown. We herein report the case of an 81-year-old Japanese woman who presented with a left hand drop. Brain magnetic resonance imaging revealed an acute infarction as the causative lesion at the inferior level of the anteromedial portion of the posterior limb of the right internal capsule. This case report indicates the topography of hand fibers in the internal capsule.
  • 下竹 昭寛, 藤田 祐之, 池田 昭夫, 冨本 秀和, 高橋 潤, 高橋 良輔
    臨床神経学
    2008年 48 巻 3 号 208-210
    発行日: 2008年
    公開日: 2008/04/15
    ジャーナル フリー
    発作時に失算,失書,手指失認を呈した症候性部分てんかんの1例を報告した.症例は34歳の男性である.反復的に,携帯電話でのメールの文字がさがしにくい,文字が書けない,計算ができなくなるエピソードを自覚し,頻回に検査課題を試みることでGerstmann症候群の3徴が明らかとなった.脳波と画像所見より左頭頂部からの部分発作による機能脱落症状と考えられた.
  • 田中 良典, 山ノ井 髙洋, 大槻 美佳, 豊島 恒
    会議録・要旨集 フリー
    著者らは,被験者がひらがなの単語を見ている時,そして一文字漢字を想起している時の脳波(EEGs)を計測した.ひらがなは被験者に対し,ランダムに提示された.各単語は複数のひらがなから成り,いくつかの同音漢字を持つ.これらの脳波を加算した事象関連電位(ERPs)に等価電流双極子推定法(ECDL)を適用した.ECDは初期視覚野(V1),腹側経路(下側頭回),Broca野などで推定された.その他にもECDは海馬傍回,紡錘状回などで推定された.これらの推定結果を比較することで被験者間の差異を確認する.
  • Wang CHUNG-CHENG, Yang JUNG-DA
    脳卒中
    1984年 6 巻 1 号 39-41
    発行日: 1984/03/25
    公開日: 2009/09/03
    ジャーナル フリー
    In 1979, Goldsmith et al, first reported on the topic of “Omental transposition to brain of stroke patients”. Since then, China began top ractise this procedure in many parts of the country. This paper presents 66 cases treated with omentum transplantation collected from nine medical units in this country.
    Sex : male 55, Female 13. Age ranged from 25 to 68; the duration of illness from 2 months to 5 years.
    Out of the 66 cases, 62 were studied angiographically before operation, which revealed evidence of internal carotid artery occulusion in 19 cases, internal carotid artery stenosis in 8, middle cerebral artery occlusion in 26, Moyamoya disease in 4, normal findings in 5.
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